Wickerhamomyces anomalus fungal keratitis responds to topical treatment with antifungal micafungin

Mamoru Kamoshita; Yukihiro Matsumoto; Kazuko Nishimura; Yasuhiro Katono; Mitsuru Murata; Yoko Ozawa; Shigeto Shimmura; Kazuo Tsubota

doi:10.1016/j.jiac.2014.08.019

Wickerhamomyces anomalus fungal keratitis responds to topical treatment with antifungal micafungin

Mamoru Kamoshita, Yukihiro Matsumoto, Kazuko Nishimura, Yasuhiro Katono, Mitsuru Murata, Yoko Ozawa, Shigeto Shimmura, Kazuo Tsubota

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Abstract

We describe a 91-year-old woman who suffered from fungal keratitis after corneal transplantation. The causative organism was identified as Wickerhamomyces anomalus (formerly Pichia anomala or Hansenula anomala) on the basis of morphological characteristics and the sequence of the internal transcribed spacer region of the ribosomal RNA gene. The patient was successfully treated with topical micafungin (MCFG) only. We present the first report of a case of W.anomalus fungal keratitis that responded to topical treatment with the antifungal MCFG.

Original language	English
Pages (from-to)	141-143
Number of pages	3
Journal	Journal of Infection and Chemotherapy
Volume	21
Issue number	2
DOIs	https://doi.org/10.1016/j.jiac.2014.08.019
Publication status	Published - 01-02-2015
Externally published	Yes

All Science Journal Classification (ASJC) codes

Microbiology (medical)
Pharmacology (medical)
Infectious Diseases

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10.1016/j.jiac.2014.08.019

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title = "Wickerhamomyces anomalus fungal keratitis responds to topical treatment with antifungal micafungin",

abstract = "We describe a 91-year-old woman who suffered from fungal keratitis after corneal transplantation. The causative organism was identified as Wickerhamomyces anomalus (formerly Pichia anomala or Hansenula anomala) on the basis of morphological characteristics and the sequence of the internal transcribed spacer region of the ribosomal RNA gene. The patient was successfully treated with topical micafungin (MCFG) only. We present the first report of a case of W.anomalus fungal keratitis that responded to topical treatment with the antifungal MCFG.",

author = "Mamoru Kamoshita and Yukihiro Matsumoto and Kazuko Nishimura and Yasuhiro Katono and Mitsuru Murata and Yoko Ozawa and Shigeto Shimmura and Kazuo Tsubota",

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doi = "10.1016/j.jiac.2014.08.019",

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T1 - Wickerhamomyces anomalus fungal keratitis responds to topical treatment with antifungal micafungin

AU - Kamoshita, Mamoru

AU - Matsumoto, Yukihiro

AU - Nishimura, Kazuko

AU - Katono, Yasuhiro

AU - Murata, Mitsuru

AU - Ozawa, Yoko

AU - Shimmura, Shigeto

AU - Tsubota, Kazuo

PY - 2015/2/1

Y1 - 2015/2/1

N2 - We describe a 91-year-old woman who suffered from fungal keratitis after corneal transplantation. The causative organism was identified as Wickerhamomyces anomalus (formerly Pichia anomala or Hansenula anomala) on the basis of morphological characteristics and the sequence of the internal transcribed spacer region of the ribosomal RNA gene. The patient was successfully treated with topical micafungin (MCFG) only. We present the first report of a case of W.anomalus fungal keratitis that responded to topical treatment with the antifungal MCFG.

AB - We describe a 91-year-old woman who suffered from fungal keratitis after corneal transplantation. The causative organism was identified as Wickerhamomyces anomalus (formerly Pichia anomala or Hansenula anomala) on the basis of morphological characteristics and the sequence of the internal transcribed spacer region of the ribosomal RNA gene. The patient was successfully treated with topical micafungin (MCFG) only. We present the first report of a case of W.anomalus fungal keratitis that responded to topical treatment with the antifungal MCFG.

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JO - Journal of Infection and Chemotherapy

JF - Journal of Infection and Chemotherapy

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ER -

Wickerhamomyces anomalus fungal keratitis responds to topical treatment with antifungal micafungin

Abstract

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