Zinc-dependent binding between peptides derived from rainbow trout CD8α and LCK

Nobuhiro Hayashi; Masami Takeuchi; Teruyuki Nakanishi; Keiichiro Hashimoto; J・m Dijkstra

doi:10.1016/j.fsi.2009.09.020

Zinc-dependent binding between peptides derived from rainbow trout CD8α and LCK

Nobuhiro Hayashi, Masami Takeuchi, Teruyuki Nakanishi, Keiichiro Hashimoto, J・m Dijkstra

Division of Biomedical Polymer Science

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Abstract

The cytoplasmic tail of mammalian CD8α binds the kinase LCK in a zinc-dependent manner. In analogy with a previous study for humans (Kim et al., 2003) peptides were synthesized from rainbow trout CD8α and LCK. Surface plasmon resonance (SPR) analysis indicated that also in fish these molecules bind to each other in a zinc-dependent manner.

Original language	English
Pages (from-to)	72-76
Number of pages	5
Journal	Fish and Shellfish Immunology
Volume	28
Issue number	1
DOIs	https://doi.org/10.1016/j.fsi.2009.09.020
Publication status	Published - 01-01-2010

All Science Journal Classification (ASJC) codes

Environmental Chemistry
Aquatic Science

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abstract = "The cytoplasmic tail of mammalian CD8α binds the kinase LCK in a zinc-dependent manner. In analogy with a previous study for humans (Kim et al., 2003) peptides were synthesized from rainbow trout CD8α and LCK. Surface plasmon resonance (SPR) analysis indicated that also in fish these molecules bind to each other in a zinc-dependent manner.",

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