Zinc-dependent binding between peptides derived from rainbow trout CD8α and LCK

Nobuhiro Hayashi, Masami Takeuchi, Teruyuki Nakanishi, Keiichiro Hashimoto, J・m Dijkstra

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

The cytoplasmic tail of mammalian CD8α binds the kinase LCK in a zinc-dependent manner. In analogy with a previous study for humans (Kim et al., 2003) peptides were synthesized from rainbow trout CD8α and LCK. Surface plasmon resonance (SPR) analysis indicated that also in fish these molecules bind to each other in a zinc-dependent manner.

Original languageEnglish
Pages (from-to)72-76
Number of pages5
JournalFish and Shellfish Immunology
Volume28
Issue number1
DOIs
Publication statusPublished - 01-01-2010

All Science Journal Classification (ASJC) codes

  • Environmental Chemistry
  • Aquatic Science

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