病態モデル先端医学研究センター

2023

Examination of postmortem changes in the lungs, trachea, and bronchi in a rat model imaged with small-animal computed tomography

Matsuyama, T., Ota, S., Inui, Y., Fujii, N., Tsukamoto, T., Isobe, I., Tsujioka, K., Nagao, S., Tanabe, R. & Toyama, H., 01-05-2023, In: Fujita medical journal. 9, 2, p. 101-104 4 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

High salt induces cognitive impairment via the interaction of the angiotensin II-AT₁ and prostaglandin E2-EP₁ systems

Kubota, H., Kunisawa, K., Wulaer, B., Hasegawa, M., Kurahashi, H., Sakata, T., Tezuka, H., Kugita, M., Nagao, S., Nagai, T., Furuyashiki, T., Narumiya, S., Saito, K., Nabeshima, T. & Mouri, A., 2023, (印刷中) In: British Journal of Pharmacology.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Treatment of tubular damage in high-fat-diet-fed obese mice using sodium-glucose cotransporter inhibitors

Saitoh, S., Takaki, T., Nakajima, K., Wo, B., Terashima, H., Shimo, S., Nguyen, H. B., Thai, T. Q., Kumamoto, K., Kunisawa, K., Nagao, S., Tojo, A., Ohno, N. & Takahashi, K., 02-2023, In: PloS one. 18, 2 February, e0281770.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

2022

Association between vascular endothelial growth factor-mediated blood–brain barrier dysfunction and stress-induced depression

Matsuno, H., Tsuchimine, S., O’Hashi, K., Sakai, K., Hattori, K., Hidese, S., Nakajima, S., Chiba, S., Yoshimura, A., Fukuzato, N., Kando, M., Tatsumi, M., Ogawa, S., Ichinohe, N., Kunugi, H. & Sohya, K., 09-2022, In: Molecular Psychiatry. 27, 9, p. 3822-3832 11 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

12 被引用数 (Scopus)

Rotavirus incapable of NSP6 expression can cause diarrhea in suckling mice

Fukuda, S., Kugita, M., Higashimoto, Y., Shiogama, K., Tsujikawa, H., Moriguchi, K., Ito, N., Sugiyama, M., Nagao, S., Murata, T., Taniguchi, K. & Komoto, S., 2022, In: Journal of General Virology. 103, 5, 001745.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

1 被引用数 (Scopus)

2020

Development and evaluation of a novel loop-mediated isothermal amplification (LAMP) method targeting Theileria parasites infecting Yezo sika deer

Shirozu, T., Badolo, A., Soga, A., Yoshimura, A., Morishita, Y. K., Koketsu, M., Shirafuji, R. U., Inokuma, H., Yokoyama, N. & Fukumoto, S., 08-2020, In: Parasitology International. 77, 102130.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

2 被引用数 (Scopus)

2019

Generation of infectious recombinant human rotaviruses from just 11 cloned cDNAs encoding the rotavirus genome

Komoto, S., Fukuda, S., Kugita, M., Hatazawa, R., Koyama, C., Katayama, K., Murata, T. & Taniguchi, K., 2019, In: Journal of Virology. 93, 8, Y.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

30 被引用数 (Scopus)

Gut microbiome-derived phenyl sulfate contributes to albuminuria in diabetic kidney disease

Kikuchi, K., Saigusa, D., Kanemitsu, Y., Matsumoto, Y., Thanai, P., Suzuki, N., Mise, K., Yamaguchi, H., Nakamura, T., Asaji, K., Mukawa, C., Tsukamoto, H., Sato, T., Oikawa, Y., Iwasaki, T., Oe, Y., Tsukimi, T., Fukuda, N. N., Ho, H. J., Nanto-Hara, F., & 36 othersOgura, J., Saito, R., Nagao, S., Ohsaki, Y., Shimada, S., Suzuki, T., Toyohara, T., Mishima, E., Shima, H., Akiyama, Y., Akiyama, Y., Ichijo, M., Matsuhashi, T., Matsuo, A., Ogata, Y., Yang, C. C., Suzuki, C., Breeggemann, M. C., Heymann, J., Shimizu, M., Ogawa, S., Takahashi, N., Suzuki, T., Owada, Y., Kure, S., Mano, N., Soga, T., Wada, T., Kopp, J. B., Fukuda, S., Hozawa, A., Yamamoto, M., Ito, S., Wada, J., Tomioka, Y. & Abe, T., 01-12-2019, In: Nature communications. 10, 1, 1835.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

125 被引用数 (Scopus)

Increased salt intake does not worsen the progression of renal cystic disease in high water-loaded PCK rats

Nagao, S., Kugita, M., Kumamoto, K., Yoshimura, A., Nishii, K. & Yamaguchi, T., 03-2019, In: PloS one. 14, 3, e0207461.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

1 被引用数 (Scopus)

2018

The Sox2 promoter-driven CD63-GFP transgenic rat model allows tracking of neural stem cell-derived extracellular vesicles

Yoshimura, A., Adachi, N., Matsuno, H., Kawamata, M., Yoshioka, Y., Kikuchi, H., Odaka, H., Numakawa, T., Kunugi, H., Ochiya, T. & Tamai, Y., 01-2018, In: DMM Disease Models and Mechanisms. 11, 1, dmm028779.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

14 被引用数 (Scopus)

2017

Beneficial effect of combined treatment with octreotide and pasireotide in PCK rats, an orthologous model of human autosomal recessive polycystic kidney disease

Kugita, M., Nishii, K., Yamaguchi, T., Suzuki, A., Yuzawa, Y., Horie, S., Higashihara, E. & Nagao, S., 05-2017, In: PloS one. 12, 5, e0177934.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

14 被引用数 (Scopus)

Mitochondrial abnormality facilitates cyst formation in autosomal dominant polycystic kidney disease

Ishimoto, Y., Inagi, R., Yoshihara, D., Kugita, M., Nagao, S., Shimizu, A., Takeda, N., Wake, M., Honda, K., Zhou, J. & Nangaku, M., 01-12-2017, In: Molecular and Cellular Biology. 37, 24, e00337-17.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

77 被引用数 (Scopus)

Reverse genetics system demonstrates that rotavirus nonstructural protein NSP6 is not essential for viral replication in cell cultures

Komoto, S., Kanai, Y., Fukuda, S., Kugita, M., Kawagishi, T., Ito, N., Sugiyama, M., Matsuura, Y., Kobayashi, T. & Taniguchi, K., 01-11-2017, In: Journal of Virology. 91, 21, e00695-17.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

35 被引用数 (Scopus)

2015

Cyclooxygenase product inhibition with acetylsalicylic acid slows disease progression in the Han:SPRD-Cy rat model of polycystic kidney disease

Ibrahim, N. H. M., Gregoire, M., Devassy, J. G., Wu, Y., Yoshihara, D., Yamaguchi, T., Nagao, S. & Aukema, H. M., 01-2015, In: Prostaglandins and Other Lipid Mediators. 116-117, p. 19-25 7 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

16 被引用数 (Scopus)

2013

Telmisartan ameliorates fibrocystic liver disease in an orthologous rat model of human autosomal recessive polycystic kidney disease

Yoshihara, D., Kugita, M., Sasaki, M., Horie, S., Nakanishi, K., Abe, T., Aukema, H. M., Yamaguchi, T. & Nagao, S., 06-12-2013, In: PloS one. 8, 12, e81480.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

20 被引用数 (Scopus)

2012

Global gene expression profiling in PPAR-γ agonist-treated kidneys in an orthologous rat model of human autosomal recessive polycystic kidney disease

Yoshihara, D., Kugita, M., Yamaguchi, T., Aukema, H. M., Kurahashi, H., Morita, M., Hiki, Y., Calvet, J. P., Wallace, D. P., Toyohara, T., Abe, T. & Nagao, S., 2012, In: PPAR Research. 695898.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

11 被引用数 (Scopus)

Structure and function of the pancreas in the polycystic kidney rat

Yi, L., Naruse, S., Furuya, S., Yamamoto, A., Nakakuki, M., Nagao, S., Yoshihara, D., Ko, S. B. H., Wei, M., Kondo, T. & Ishiguro, H., 11-2012, In: Pancreas. 41, 8, p. 1292-1298 7 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

2 被引用数 (Scopus)

2011

PPAR-γ agonist ameliorates kidney and liver disease in an orthologous rat model of human autosomal recessive polycystic kidney disease

Yoshihara, D., Kurahashi, H., Morita, M., Kugita, M., Hiki, Y., Aukema, H. M., Yamaguchi, T., Calvet, J. P., Wallace, D. P. & Nagao, S., 02-2011, In: American Journal of Physiology - Renal Physiology. 300, 2, p. F465-F474

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

71 被引用数 (Scopus)

2010

Effects of transgenic Pit-1 overexpression on calcium phosphate and bone metabolism

Suzuki, A., Ammann, P., Nishiwaki-Yasuda, K., Sekiguchi, S., Asano, S., Nagao, S., Kaneko, R., Hirabayashi, M., Oiso, Y., Itoh, M. & Caverzasio, J., 03-2010, In: Journal of Bone and Mineral Metabolism. 28, 2, p. 139-148 10 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

34 被引用数 (Scopus)

PD-1/B7-H1 interaction contribute to the spontaneous acceptance of mouse liver allograft

Morita, M., Fujino, M., Jiang, G., Kitazawa, Y., Xie, L., Azuma, M., Yagita, H., Nagao, S., Sugioka, A., Kurosawa, Y., Takahara, S., Fung, J., Qian, S., Lu, L. & Li, X. K., 01-2010, In: American Journal of Transplantation. 10, 1, p. 40-46 7 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

62 被引用数 (Scopus)

Polycystic kidney disease in Han:SPRD Cy rats is associated with elevated expression and mislocalization of SamCystin

Nagao, S., Morita, M., Kugita, M., Yoshihara, D., Yamaguchi, T., Kurahashi, H., Calvet, J. P. & Wallace, D. P., 11-2010, In: American Journal of Physiology - Renal Physiology. 299, 5, p. F1078-F1086

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

21 被引用数 (Scopus)

2008

Generation of recombinant rotavirus with an antigenic mosaic of cross-reactive neutralization epitopes on VP4

Komoto, S., Kugita, M., Sasaki, J. & Taniguchi, K., 07-2008, In: Journal of Virology. 82, 13, p. 6753-6757 5 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

33 被引用数 (Scopus)

2007

Expression levels of Egr-1 and Nur77 proteins in mouse brain are increased by withdrawal of nicotine

Yamada, K., Sawada, H., Nishii, K., Ichino, N., Hida, T., Nagao, S., Takahashi, H., Ishiguro, H. & Nagatsu, T., 2007, In: Biogenic Amines. 21, 4, p. 183-194 12 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

2006

Increased water intake decreases progression of polycystic kidney disease in the PCK rat

Nagao, S., Nishii, K., Katsuyama, M., Kurahashi, H., Marunouchi, T., Takahashi, H. & Wallace, D. P., 08-2006, In: Journal of the American Society of Nephrology. 17, 8, p. 2220-2227 8 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

194 被引用数 (Scopus)

2003

Cyclic AMP activates B-Raf and ERK in cyst epithelial cells from autosomal-dominant polycystic kidneys

Yamaguchi, T., Nagao, S., Wallace, D. P., Belibi, F. A., Cowley, B. D., Pelling, J. C. & Grantham, J. J., 01-06-2003, In: Kidney International. 63, 6, p. 1983-1994 12 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

146 被引用数 (Scopus)

1997

A renal carcinogen causes inhibition of cyst formation in the Cy rat model of polycystic kidney disease

Nagao, S., Tsuda, H., Kato, M., Ogiso, N., Yamaguchi, T., Marunouchi, T., Kasahara, M. & Takahashi, H., 1997, In: FASEB Journal. 11, 3, p. A518

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Evidence for increased renal production of cyclic AMP in mice with hereditary slowly progressive polycystic kidney disease

Yamaguchi, T., Ito, S., Nagao, S., Kasahara, M., Takahashi, H. & Grantham, J. J., 01-12-1997, In: FASEB Journal. 11, 3, p. A82

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Renal accumulation and excretion of cyclic adenosine monophosphate in a murine model of slowly progressive polycystic kidney disease

Yamaguchi, T., Nagao, S., Kasahara, M., Takahashi, H. & Grantham, J. J., 11-1997, In: American Journal of Kidney Diseases. 30, 5, p. 703-709 7 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

110 被引用数 (Scopus)

The effect of paclitaxel on the progression of polycystic kidney disease in rodents

Martinez, J. R., Cowley, B. D., Gattone, V. H., Nagao, S., Yamaguchi, T., Kaneta, S., Takahashi, H. & Grantham, J. J., 03-1997, In: American Journal of Kidney Diseases. 29, 3, p. 435-444 10 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

12 被引用数 (Scopus)

1993

Decreased Dimethylnitrosamine‐induced O⁶‐ and N7‐Methyldeoxyguanosine Levels Correlate with Development and Progression of Lesions in Rat Hepatocarcinogenesis

Ozaki, K., Kato, T., Asamoto, M., Wild, C. P., Montesano, R., Nagao, S., Iwase, T., Matsumoto, K. & Tsuda, H., 12-1993, In: Japanese Journal of Cancer Research. 84, 12, p. 1245-1251 7 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

Number of Simultaneously Expressed Enzyme Alterations Correlates with Progression of N‐Ethyl‐N‐hydroxyethylnitrosamine‐induced Hepatocarcinogenesis in Rats

Yamaguchi, S., Hakoi, K., Ozaki, K., Kato, T., Tiwawech, D., Nagao, S., Takahashi, H., Matsumoto, K. & Tsuda, H., 12-1993, In: Japanese Journal of Cancer Research. 84, 12, p. 1237-1244 8 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

1 被引用数 (Scopus)

1990

Isolation and culture of panning method-enriched Langerhans cells from dispase-dissociated epidermal cells of the mouse

Koyama, Y., Kobayashi, M., Ohashi, K., Nagao, S., Niwa, J., Takahashi, H., Hoshino, T. & Marunouchi, T., 1990, In: Journal of Dermatology. 17, 4, p. 211-217 7 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

10 被引用数 (Scopus)

1989

Effect of systemic and topical application of testosterone propionate on the density of epidermal langerhans cells in the mouse

Koyama, Y. I., Nagao, S., Ohashi, K., Takahashi, H. & Marunouchi, T., 01-1989, In: Journal of Investigative Dermatology. 92, 1, p. 86-90 5 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

10 被引用数 (Scopus)

病態モデル先端医学研究センター

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