研究成果 1984 2019

2019
1 引用 (Scopus)
公開
metastasis
cancer
Neoplasm Metastasis
Proteins
Messenger RNA
1 引用 (Scopus)
Polyribosomes
Endoplasmic Reticulum
Protein Biosynthesis
Protein Splicing
Messenger RNA
2018
5 引用 (Scopus)

HMGA1a induces alternative splicing of estrogen receptor alpha in MCF-7 human breast cancer cells

Ohe, K., Miyajima, S., Abe, I., Tanaka, T., Hamaguchi, Y., Harada, Y., Horita, Y., Beppu, Y., Ito, F., Yamasaki, T., Terai, H., Mori, M., Murata, Y., Tanabe, M., Ashida, K., Kobayashi, K., Enjoji, M., Yanase, T., Harada, N., Utsumi, T. および1人, Mayeda, A., 09-2018, : : Journal of Steroid Biochemistry and Molecular Biology. 182, p. 21-26 6 p.

研究成果: Article

High Mobility Group Proteins
Estrogen Receptor alpha
Alternative Splicing
Cells
Breast Neoplasms
2 引用 (Scopus)

HMGA1a induces alternative splicing of the estrogen receptor-alpha gene by trapping U1 snRNP to an upstream pseudo-5' splice site

Ohe, K., Miyajima, S., Tanaka, T., Hamaguchi, Y., Harada, Y., Horita, Y., Beppu, Y., Ito, F., Yamasaki, T., Terai, H., Mori, M., Murata, Y., Tanabe, M., Abe, I., Ashida, K., Kobayashi, K., Enjoji, M., Nomiyama, T., Yanase, T., Harada, N. および2人, Utsumi, T. & Mayeda, A., 08-06-2018, : : Frontiers in Molecular Biosciences. 5, JUN, 52.

研究成果: Article

U1 Small Nuclear Ribonucleoproteins
High Mobility Group Proteins
RNA Splice Sites
Estrogen Receptor alpha
Alternative Splicing
2 引用 (Scopus)

Rearrangement of VPS13B, a causative gene of Cohen syndrome, in a case of RUNX1–RUNX1T1 leukemia with t(8;12;21)

Abe, A., Yamamoto, Y., Katsumi, A., Okamoto, A., Tokuda, M., Inaguma, Y., Yamamoto, K., Yanada, M., Kanie, T., Tomita, A., Akatsuka, Y., Okamoto, M., Kameyama, T., Mayeda, A. & Emi, N., 01-08-2018, : : International Journal of Hematology. 108, 2, p. 208-212 5 p.

研究成果: Article

Acute Myeloid Leukemia
Leukemia
Reading Frames
Genetic Translocation
Gene Fusion
3 引用 (Scopus)
Aurora Kinase B
RNA Precursors
Quality Control
Quality control
Messenger RNA
2017
8 引用 (Scopus)
bootstrapping
topology
user interface
phylogeny
Phylogeny
16 引用 (Scopus)

Global analysis of pre-mRNA subcellular localization following splicing inhibition by spliceostatin A

Yoshimoto, R., Kaida, D., Furuno, M., Burroughs, A. M., Noma, S., Suzuki, H., Kawamura, Y., Hayashizaki, Y., Mayeda, A. & Yoshida, M., 01-2017, : : RNA. 23, 1, p. 47-57 11 p.

研究成果: Article

RNA Precursors
RNA Splice Sites
Introns
U2 Small Nuclear Ribonucleoproteins
Cyclin-Dependent Kinase Inhibitor p27
2016
10 引用 (Scopus)

Control of the heat stress-induced alternative splicing of a subset of genes by hnRNP K

Yamamoto, K., Furukawa, M. T., Fukumura, K., Kawamura, A., Yamada, T., Suzuki, H., Hirose, T., Sakamoto, H. & Inoue, K., 01-09-2016, : : Genes to Cells. 21, 9, p. 1006-1014 9 p.

研究成果: Article

Heterogeneous-Nuclear Ribonucleoprotein K
Alternative Splicing
Hot Temperature
Heat-Shock Response
Exons
18 引用 (Scopus)

Endogenous multiple exon skipping and back-splicing at the DMD mutation hotspot

Suzuki, H., Aoki, Y., Kameyama, T., Saito, T., Masuda, S., Tanihata, J., Nagata, T., Mayeda, A., Takeda, SI. & Tsukahara, T., 13-10-2016, : : International journal of molecular sciences. 17, 10, 1722.

研究成果: Article

splicing
Duchenne Muscular Dystrophy
mutations
RNA
Exons
7 引用 (Scopus)

ETV6-LPXN fusion transcript generated by t(11;12)(q12.1;p13) in a patient with relapsing acute myeloid leukemia with NUP98-HOXA9

Abe, A., Yamamoto, Y., Iba, S., Kanie, T., Okamoto, A., Tokuda, M., Inaguma, Y., Yanada, M., Morishima, S., Mizuta, S., Akatsuka, Y., Okamoto, M., Kameyama, T., Mayeda, A. & Emi, N., 01-03-2016, : : Genes Chromosomes and Cancer. 55, 3, p. 242-250 9 p.

研究成果: Article

Acute Myeloid Leukemia
Leukemia
Granulocyte Colony-Stimulating Factor
Exons
Chemokine CXCL12

Fluvoxamine reverses estrogen-dependent decline in voluntary activities and decreased amygdala levels of serotonin in ovariectomized rats

Lshibashi, Y., Lzumo, N., Lwata, K., Morikawa, T., Kameyama, T., Watanabe, Y., Manabe, T. & Matsuzaki, H., 30-06-2016, : : Journal of Brain Science. 46, p. 5-19 15 p.

研究成果: Article

Fluvoxamine
Amygdala
Serotonin
Estrogens
Brain-Derived Neurotrophic Factor
102 引用 (Scopus)

MALAT1 long non-coding RNA in cancer

Yoshimoto, R., Mayeda, A., Yoshida, M. & Nakagawa, S., 01-01-2016, : : Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1859, 1, p. 192-199 8 p.

研究成果: Article

Long Noncoding RNA
Neoplasm Metastasis
Untranslated RNA
Alternative Splicing
Pathology
6 引用 (Scopus)

Selection pressure on human STR loci and its relevance in repeat expansion disease

Shimada, M. K., Sanbonmatsu, R., Yamaguchi-Kabata, Y., Yamasaki, C., Suzuki, Y., Chakraborty, R., Gojobori, T. & Imanishi, T., 01-10-2016, : : Molecular Genetics and Genomics. 291, 5, p. 1851-1869 19 p.

研究成果: Article

Microsatellite Repeats
Pressure
Neurodegenerative Diseases
DNA
Biological Phenomena
10 引用 (Scopus)
splicing
progressions
set theory
Exons
Cell Cycle
1 引用 (Scopus)
Proto-Oncogene Proteins c-ets
Platelet-Derived Growth Factor alpha Receptor
Repressor Proteins
Homeodomain Proteins
Chemical activation
2015
6 引用 (Scopus)
genome
RNA Precursors
nucleotides
Human Genome
Nucleotides

Identification of the specific interactors of the human lariat RNA debranching enzyme 1 protein

Masaki, S., Yoshimoto, R., Kaida, D., Hata, A., Satoh, T., Ohno, M. & Kataoka, N., 09-02-2015, : : International journal of molecular sciences. 16, 2, p. 3705-3721 17 p.

研究成果: Article

RNA
enzymes
Enzymes
proteins
Proteins

NUP214-RAC1 and RAC1-COL12A1 Fusion in Complex Variant Translocations Involving Chromosomes 6, 7 and 9 in an Acute Myeloid Leukemia Case with DEK-NUP214

Abe, A., Yamamoto, Y., Iba, S., Okamoto, A., Tokuda, M., Inaguma, Y., Yanada, M., Morishima, S., Kanie, T., Tsuzuki, M., Akatsuka, Y., Mizuta, S., Okamoto, M., Kameyama, T., Maeda, A. & Emi, N., 01-12-2015, : : Cytogenetic and Genome Research. 146, 4, p. 279-284 6 p.

研究成果: Article

Chromosomes, Human, Pair 9
Chromosomes, Human, Pair 6
Chromosomes, Human, Pair 7
Acute Myeloid Leukemia
Introns
2014
9 引用 (Scopus)

Fluvoxamine moderates reduced voluntary activity following chronic dexamethasone infusion in mice via recovery of BDNF signal cascades

Terada, K., Izumo, N., Suzuki, B., Karube, Y., Morikawa, T., Ishibashi, Y., Kameyama, T., Chiba, K., Sasaki, N., Iwata, K., Matsuzaki, H. & Manabe, T., 01-01-2014, : : Neurochemistry International. 69, 1, p. 9-13 5 p.

研究成果: Article

Fluvoxamine
Brain-Derived Neurotrophic Factor
Dexamethasone
Locomotion
Serotonin Uptake Inhibitors
10 引用 (Scopus)
RNA Precursors
Introns
Proteins
Immunoprecipitation
Mass Spectrometry
15 引用 (Scopus)
Zinc Fingers
Nervous System
Transcription Factors
Genes
Nerve Tissue
4 引用 (Scopus)

Splicing inhibition induces gene expression through canonical NF-κB pathway and extracellular signal-related kinase activation

Khan, K., Schneider-Poetsch, T., Ishfaq, M., Ito, A., Yoshimoto, R., Mukaida, N. & Yoshida, M., 18-03-2014, : : FEBS Letters. 588, 6, p. 1053-1057 5 p.

研究成果: Article

Gene expression
Signal Transduction
Phosphotransferases
Chemical activation
Gene Expression
2013
21 引用 (Scopus)

HnRNP L and hnRNP LL antagonistically modulate PTB-mediated splicing suppression of CHRNA1 pre-mRNA

Rahman, M. A., Masuda, A., Ohe, K., Ito, M., Hutchinson, D. O., Mayeda, A., Engel, A. G. & Ohno, K., 25-10-2013, : : Scientific reports. 3, 2931.

研究成果: Article

Heterogeneous-Nuclear Ribonucleoprotein L
RNA Precursors
Exons
Heterogeneous-Nuclear Ribonucleoproteins
RNA-Binding Proteins
18 引用 (Scopus)

Nested introns in an intron: Evidence of multi-step splicing in a large intron of the human dystrophin pre-mRNA

Suzuki, H., Kameyama, T., Ohe, K., Tsukahara, T. & Mayeda, A., 18-03-2013, : : FEBS Letters. 587, 6, p. 555-561 7 p.

研究成果: Article

Dystrophin
RNA Precursors
RNA Splice Sites
Introns
Exoribonucleases
2012
8 引用 (Scopus)

Detection of pre-mRNA splicing in vitro by an RNA-templated fluorogenic reaction

Tamura, Y., Furukawa, K., Yoshimoto, R., Kawai, Y., Yoshida, M., Tsuneda, S., Ito, Y. & Abe, H., 01-12-2012, : : Bioorganic and Medicinal Chemistry Letters. 22, 23, p. 7248-7251 4 p.

研究成果: Article

RNA Precursors
Fluorescence
RNA
RNA Splicing
Messenger RNA
107 引用 (Scopus)

Identification of cis- and trans-acting factors involved in the localization of MALAT-1 noncoding RNA to nuclear speckles

Miyagawa, R., Tano, K., Mizuno, R. I. E., Nakamura, Y. O., Ijiri, K., Rakwal, R., Shibato, J., Masuo, Y., Mayeda, A., Hirose, T. & Akimitsu, N., 01-04-2012, : : RNA. 18, 4, p. 738-751 14 p.

研究成果: Article

Untranslated RNA
Trans-Activators
Gene Expression
Messenger RNA
Gene Expression Regulation
4 引用 (Scopus)

In Vitro Splicing Assays

Mayeda, A. & Krainer, A. R., 02-02-2012, Alternative pre-mRNA Splicing: Theory and Protocols. Wiley-VCH, p. 320-329 10 p.

研究成果: Chapter

Assays
Trans-Activators
RNA Precursors
Alternative Splicing
Cell Extracts
10 引用 (Scopus)
RNA Precursors
Introns
Genes
U2 Small Nuclear Ribonucleoproteins
Protein Splicing
3 引用 (Scopus)

Prediction of Protein-Destabilizing Polymorphisms by Manual Curation with Protein Structure

Gough, C. A., Homma, K., Yamaguchi-Kabata, Y., Shimada, M. K., Chakraborty, R., Fujii, Y., Iwama, H., Minoshima, S., Sakamoto, S., Sato, Y., Suzuki, Y., Tada-Umezaki, M., Nishikawa, K., Imanishi, T. & Gojobori, T., 26-11-2012, : : PloS one. 7, 11, e50445.

研究成果: Article

protein structure
Polymorphism
genetic polymorphism
prediction
single nucleotide polymorphism
19 引用 (Scopus)
RNA Splice Sites
Exons
Messenger RNA
Neoplasms
RNA Precursors
15 引用 (Scopus)

SAP155-mediated splicing of FUSE-binding protein-interacting repressor serves as a molecular switch for c-myc gene expression

Matsushita, K., Kajiwara, T., Tamura, M., Satoh, M., Tanaka, N., Tomonaga, T., Matsubara, H., Shimada, H., Yoshimoto, R., Ito, A., Kubo, S., Natsume, T., Levens, D., Yoshida, M. & Nomura, F., 01-06-2012, : : Molecular Cancer Research. 10, 6, p. 787-799 13 p.

研究成果: Article

myc Genes
RNA Precursors
Carrier Proteins
Gene Expression
Colorectal Neoplasms
2011
85 引用 (Scopus)

Competition between a noncoding exon and introns: Gomafu contains tandem UACUAAC repeats and associates with splicing factor-1

Tsuiji, H., Yoshimoto, R., Hasegawa, Y., Furuno, M., Yoshida, M. & Nakagawa, S., 01-05-2011, : : Genes to Cells. 16, 5, p. 479-490 12 p.

研究成果: Article

Tandem Repeat Sequences
Introns
Exons
RNA
Physiological Phenomena
24 引用 (Scopus)

Fluorescence detection of intron lariat RNA with reduction-triggered fluorescent probes

Furukawa, K., Abe, H., Tamura, Y., Yoshimoto, R., Yoshida, M., Tsuneda, S. & Ito, Y., 09-12-2011, : : Angewandte Chemie - International Edition. 50, 50, p. 12020-12023 4 p.

研究成果: Article

Fluorescein
RNA
Fluorescent Dyes
Introns
Bearings (structural)
11 引用 (Scopus)

Myt/NZF family transcription factors regulate neuronal differentiation of P19 cells

Kameyama, T., Matsushita, F., Kadokawa, Y. & Marunouchi, T., 22-06-2011, : : Neuroscience Letters. 497, 2, p. 74-79 6 p.

研究成果: Article

Zinc Fingers
Myelin Sheath
Cell Differentiation
Transcription Factors
Myelin Proteolipid Protein
2010
9 引用 (Scopus)
alternative splicing
exons
polymorphism
genetic polymorphism
single nucleotide polymorphism
23 引用 (Scopus)
U1 Small Nuclear Ribonucleoproteins
Small Nuclear Ribonucleoproteins
High Mobility Group Proteins
RNA Splice Sites
Exons
24 引用 (Scopus)
Untranslated RNA
Heterochromatin
Schizosaccharomyces
Centromere
Gene Silencing
9 引用 (Scopus)

The expression of HMGA1a is increased in lymphoblastoid cell lines from schizophrenia patients

Morikawa, T., Manabe, T., Ito, Y., Yamada, S., Yoshimi, A., Nagai, T., Ozaki, N. & Mayeda, A., 01-05-2010, : : Neurochemistry International. 56, 6-7, p. 736-739 4 p.

研究成果: Article

High Mobility Group Proteins
Schizophrenia
Cell Line
Presenilin-2
RNA
2009
U1 Small Nuclear Ribonucleoproteins
Alternative Splicing
Introns
Exons
Messenger RNA
HMGA1a Protein
Presenilin-2
Small Nuclear Ribonucleoproteins
RNA Splicing
RNA Splice Sites
44 引用 (Scopus)

Isolation and characterization of post-splicing lariat-intron complexes

Yoshimoto, R., Kataoka, N., Okawa, K. & Ohno, M., 24-07-2009, : : Nucleic Acids Research. 37, 3, p. 891-902 12 p.

研究成果: Article

Introns
Spliceosomes
Inteins
Protein Splicing
RNA Precursors
7 引用 (Scopus)
RNA Precursors
Alternative Splicing
U1 Small Nuclear Ribonucleoproteins
RNA Splice Sites
Gene Expression Regulation
7 引用 (Scopus)

Skewed matrilineal genetic composition in a small wild chimpanzee community

Shimada, M., Hayakawa, S., Fujita, S., Sugiyama, Y. & Saitou, N., 01-04-2009, : : Folia Primatologica. 80, 1, p. 19-32 14 p.

研究成果: Article

Pan troglodytes
haplotypes
mitochondrial DNA
kinship
extinction
23 引用 (Scopus)

U1-independent pre-mRNA splicing contributes to the regulation of alternative splicing

Fukumura, K., Taniguchi, I., Sakamoto, H., Ohno, M. & Inoue, K., 21-04-2009, : : Nucleic Acids Research. 37, 6, p. 1907-1914 8 p.

研究成果: Article

RNA Precursors
Alternative Splicing
Introns
U1 Small Nuclear Ribonucleoproteins
RNA Splice Sites
13 引用 (Scopus)

VarySysDB: A human genetic polymorphism database based on all H-InvDB transcripts

Shimada, M. K., Matsumoto, R., Hayakawa, Y., Sanbonmatsu, R., Gough, C., Yamaguchi-Kabata, Y., Yamasaki, C., Imanishi, T. & Gojobori, T., 09-01-2009, : : Nucleic Acids Research. 37, SUPPL. 1, p. D810-D815

研究成果: Article

Genetic Databases
Medical Genetics
Genetic Polymorphisms
DNA Copy Number Variations
Linkage Disequilibrium
2008
30 引用 (Scopus)

Distribution and effects of nonsense polymorphisms in human genes

Yamaguchi-Kabata, Y., Shimada, M. K., Hayakawa, Y., Minoshima, S., Chakraborty, R., Gojobori, T. & Imanishi, T., 14-10-2008, : : PloS one. 3, 10, e3393.

研究成果: Article

Polymorphism
single nucleotide polymorphism
Single Nucleotide Polymorphism
Genes
genetic polymorphism
55 引用 (Scopus)

The H-Invitational Database (H-InvDB), a comprehensive annotation resource for human genes and transcripts

Genome Information Integration Project and H-Invitational 2 Consortium, 01-2008, : : Nucleic Acids Research. 36, SUPPL. 1, p. D793-D799

研究成果: Article

Databases
Genes
Molecular Sequence Annotation
Proteins
Transcriptome
2007
13 引用 (Scopus)

Divergent haplotypes and human history as revealed in a worldwide survey of X-linked DNA sequence variation

Shimada, M. K., Panchapakesan, K., Tishkoff, S. A., Nato, A. Q. & Hey, J., 01-03-2007, : : Molecular Biology and Evolution. 24, 3, p. 687-698 12 p.

研究成果: Article

Haplotypes
haplotypes
History
nucleotide sequences
DNA
22 引用 (Scopus)

HMGA1a: Sequence-specific RNA-binding factor causing sporadic Alzheimer's disease-linked exon skipping of presenilin-2 pre-mRNA

Manabe, T., Ohe, K., Katayama, T., Matsuzaki, S., Yanagita, T., Okuda, H., Bando, Y., Imaizumi, K., Reeves, R., Tohyama, M. & Mayeda, A., 01-10-2007, : : Genes to Cells. 12, 10, p. 1179-1191 13 p.

研究成果: Article

Presenilin-2
High Mobility Group Proteins
RNA Precursors
Exons
Alzheimer Disease