血液内科学

研究成果

  • 5793 引用
  • 37 h指数
  • 213 Article
  • 11 Letter
  • 8 Review article
  • 2 Comment/debate
2020
公開

Pembrolizumab monotherapy in patients with primary refractory classical hodgkin lymphoma who relapsed after salvage autologous stem cell transplantation and/or brentuximab vedotin therapy: KEYNOTE-087 subgroup analysis

Zinzani, P. L., Chen, R., Armand, P., Johnson, N. A., Brice, P., Radford, J., Ribrag, V., Molin, D., Vassilakopoulos, T. P., Tomita, A., von Tresckow, B., Shipp, M. A., Lin, J., Nahar, A., Balakumaran, A. & Moskowitz, C. H., 20-03-2020, : : Leukemia and Lymphoma. 61, 4, p. 950-954 5 p.

研究成果: Letter

Prospective evaluation of prognostic impact of KIT mutations on acute myeloid leukemia with RUNX1-RUNX1T1 and CBFB-MYH11

Ishikawa, Y., Kawashima, N., Atsuta, Y., Sugiura, I., Sawa, M., Dobashi, N., Yokoyama, H., Doki, N., Tomita, A., Kiguchi, T., Koh, S., Kanamori, H., Iriyama, N., Kohno, A., Moriuchi, Y., Asada, N., Hirano, D., Togitani, K., Sakura, T., Hagihara, M. および8人, Tomikawa, T., Yokoyama, Y., Asou, N., Ohtake, S., Matsumura, I., Miyazaki, Y., Naoe, T. & Kiyoi, H., 14-01-2020, : : Blood Advances. 4, 1, p. 66-75 10 p.

研究成果: Article

公開

Rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone combined with high-dose methotrexate plus intrathecal chemotherapy for newly diagnosed intravascular large B-cell lymphoma (PRIMEUR-IVL): a multicentre, single-arm, phase 2 trial

Shimada, K., Yamaguchi, M., Atsuta, Y., Matsue, K., Sato, K., Kusumoto, S., Nagai, H., Takizawa, J., Fukuhara, N., Nagafuji, K., Miyazaki, K., Ohtsuka, E., Okamoto, M., Sugita, Y., Uchida, T., Kayukawa, S., Wake, A., Ennishi, D., Kondo, Y., Izumi, T. および14人, Kin, Y., Tsukasaki, K., Hashimoto, D., Yuge, M., Yanagisawa, A., Kuwatsuka, Y., Shimada, S., Masaki, Y., Niitsu, N., Kiyoi, H., Suzuki, R., Tokunaga, T., Nakamura, S. & Kinoshita, T., 04-2020, : : The Lancet Oncology. 21, 4, p. 593-602 10 p.

研究成果: Article

1 引用 (Scopus)
2019

Effect of L-leucine therapy on hematopoietic function in elderly myelodysplastic syndrome patients

Ito, K., Hayashi, T., Inaguma, Y., Terazawa, T., Ando, M., Ando, Y., Tsuge, M., Kato, A., Shimato, A., Suzuki, S., Kato, S., Tomita, A., Yamada, S. & Emi, N., 01-01-2019, : : Biological and Pharmaceutical Bulletin. 42, 10, p. 1651-1657 7 p.

研究成果: Article

公開
7 引用 (Scopus)

Epstein-Barr virus (EBV)-positive diffuse large B-cell lymphoma arising in patient with a history of EBV-positive mucocutaneous ulcer and EBV-positive nodal polymorphous B-lymphoproliferative disorder

Daroontum, T., Kohno, K., Inaguma, Y., Okamoto, A., Okamoto, M., Kimura, Y., Nagahama, M., Sakakibara, A., Satou, A. & Nakamura, S., 01-2019, : : Pathology International. 69, 1, p. 37-41 5 p.

研究成果: Article

2 引用 (Scopus)

Frequent structural variations involving programmed death ligands in Epstein-Barr virus-associated lymphomas

Kataoka, K., Miyoshi, H., Sakata, S., Dobashi, A., Couronné, L., Kogure, Y., Sato, Y., Nishida, K., Gion, Y., Shiraishi, Y., Tanaka, H., Chiba, K., Watatani, Y., Kakiuchi, N., Shiozawa, Y., Yoshizato, T., Yoshida, K., Makishima, H., Sanada, M., Onozawa, M. および18人, Teshima, T., Yoshiki, Y., Ishida, T., Suzuki, K., Shimada, K., Tomita, A., Kato, M., Ota, Y., Izutsu, K., Demachi-Okamura, A., Akatsuka, Y., Miyano, S., Yoshino, T., Gaulard, P., Hermine, O., Takeuchi, K., Ohshima, K. & Ogawa, S., 01-07-2019, : : Leukemia. 33, 7, p. 1687-1699 13 p.

研究成果: Article

公開
11 引用 (Scopus)

IV. Mantle cell lymphoma

Okamoto, M., Inaguma, Y. & Okamoto, A., 05-2019, : : Japanese Journal of Cancer and Chemotherapy. 46, 5, p. 878-883 6 p.

研究成果: Article

Pembrolizumab in relapsed or refractory Hodgkin lymphoma: 2-year follow-up of KEYNOTE-087

Chen, R., Zinzani, P. L., Lee, H. J., Armand, P., Johnson, N. A., Brice, P., Radford, J., Ribrag, V., Molin, D., Vassilakopoulos, T. P., Tomita, A., von Tresckow, B., Shipp, M. A., Lin, J., Kim, E., Nahar, A., Balakumaran, A. & Moskowitz, C. H., 03-10-2019, : : Blood. 134, 14, p. 1144-1153 10 p.

研究成果: Article

16 引用 (Scopus)

Pyruvate secreted from patient-derived cancer-associated fibroblasts supports survival of primary lymphoma cells

Sakamoto, A., Kunou, S., Shimada, K., Tsunoda, M., Aoki, T., Iriyama, C., Tomita, A., Nakamura, S., Hayakawa, F. & Kiyoi, H., 01-2019, : : Cancer science. 110, 1, p. 269-278 10 p.

研究成果: Article

10 引用 (Scopus)
2018

Comparison of the tube test and column agglutination techniques for anti-A/-B antibody titration in healthy individuals

Matsuura, H., Akatsuka, Y., Matsuno, T., Sugiura, Y., Arakawa, S., Oikawa, S., Yoshida, J., Kosugi, M. & Emi, N., 11-2018, : : Vox Sanguinis. 113, 8, p. 787-794 8 p.

研究成果: Article

1 引用 (Scopus)

Hematopoiesis by iPSC-derived hematopoietic stem cells of aplastic anemia that escape cytotoxic T-cell attack

Espinoza, J. L., Elbadry, M. I., Chonabayashi, K., Yoshida, Y., Katagiri, T., Harada, K., Nakagawa, N., Zaimoku, Y., Imi, T., Takamatsu, H., Ozawa, T., Maruyama, H., Hassanein, H. A., Noreldin, A. K. A., Takenaka, K., Akashi, K., Hamana, H., Kishi, H., Akatsuka, Y. & Nakao, S., 27-02-2018, : : Blood Advances. 2, 4, p. 390-400 11 p.

研究成果: Article

9 引用 (Scopus)
5 引用 (Scopus)
1 引用 (Scopus)

Rearrangement of VPS13B, a causative gene of Cohen syndrome, in a case of RUNX1–RUNX1T1 leukemia with t(8;12;21)

Abe, A., Yamamoto, Y., Katsumi, A., Okamoto, A., Tokuda, M., Inaguma, Y., Yamamoto, K., Yanada, M., Kanie, T., Tomita, A., Akatsuka, Y., Okamoto, M., Kameyama, T., Mayeda, A. & Emi, N., 01-08-2018, : : International Journal of Hematology. 108, 2, p. 208-212 5 p.

研究成果: Article

3 引用 (Scopus)

Role of exosomes as a proinflammatory mediator in the development of EBV-associated lymphoma

Higuchi, H., Yamakawa, N., Imadome, K. I., Yahata, T., Kotaki, R., Ogata, J., Kakizaki, M., Fujita, K., Lu, J., Yokoyama, K., Okuyama, K., Sato, A., Takamatsu, M., Kurosaki, N., Alba, S. M., Azhim, A., Horie, R., Watanabe, T., Kitamura, T., Ando, K. および7人, Kashiwagi, T., Matsui, T., Okamoto, A., Handa, H., Kuroda, M., Nakamura, N. & Kotani, A., 07-06-2018, : : Blood. 131, 23, p. 2552-2567 16 p.

研究成果: Article

16 引用 (Scopus)
2017

Altered EZH2 splicing and expression is associated with impaired histone H3 lysine 27 tri-Methylation in myelodysplastic syndrome

Shirahata-Adachi, M., Iriyama, C., Tomita, A., Suzuki, Y., Shimada, K. & Kiyoi, H., 12-2017, : : Leukemia Research. 63, p. 90-97 8 p.

研究成果: Article

13 引用 (Scopus)

A nationwide survey of hypoplastic myelodysplastic syndrome (a multicenter retrospective study)

for National Research Group on Idiopathic Bone Marrow Failure Syndromes, 12-2017, : : American Journal of Hematology. 92, 12, p. 1324-1332 9 p.

研究成果: Article

4 引用 (Scopus)

Elevated serum interferon Î 3-induced protein 10 kDa is associated with TAFRO syndrome

Iwaki, N., Gion, Y., Kondo, E., Kawano, M., Masunari, T., Moro, H., Nikkuni, K., Takai, K., Hagihara, M., Hashimoto, Y., Yokota, K., Okamoto, M., Nakao, S., Yoshino, T. & Sato, Y., 13-02-2017, : : Scientific reports. 7, 42316.

研究成果: Article

公開
27 引用 (Scopus)

Emetine elicits apoptosis of intractable B-cell lymphoma cells with MYC rearrangement through inhibition of glycolytic metabolism

Aoki, T., Shimada, K., Sakamoto, A., Sugimoto, K., Morishita, T., Kojima, Y., Shimada, S., Kato, S., Iriyama, C., Kuno, S., Harada, Y., Tomita, A., Hayakawa, F. & Kiyoi, H., 01-01-2017, : : Oncotarget. 8, 8, p. 13085-13098 14 p.

研究成果: Article

9 引用 (Scopus)

Erratum to: Japanese phase II study of rituximab maintenance for untreated indolent B-cell non-Hodgkin lymphoma with high tumor burden (International Journal of Hematology, (2016), 104, 6, (700-708), 10.1007/s12185-016-2097-9)

Igarashi, T., Ogura, M., Itoh, K., Taniwaki, M., Ando, K., Kuroda, Y., Yamamoto, K., Uike, N., Tomita, A., Nagai, H., Kurosawa, M., Mori, S., Nawano, S., Terauchi, T., Ohashi, Y. & Tobinai, K., 01-01-2017, : : International Journal of Hematology. 105, 1, p. 109-110 2 p.

研究成果: Comment/debate

Reappraisal of Epstein–Barr virus (EBV) in diffuse large B-cell lymphoma (DLBCL): comparative analysis between EBV-positive and EBV-negative DLBCL with EBV-positive bystander cells

Ohashi, A., Kato, S., Okamoto, A., Inaguma, Y., Satou, A., Tsuzuki, T., Emi, N., Okamoto, M. & Nakamura, S., 07-2017, : : Histopathology. 71, 1, p. 89-97 9 p.

研究成果: Article

8 引用 (Scopus)

Successful treatment with allogeneic stem cell transplantation followed by DLI and TKIs for e6a2 BCR-ABL -positive acute myeloid leukaemia: A case report and literature review

Harada, Y., Nishiwaki, S., Sugimoto, T., Onodera, K., Goto, T., Sato, T., Kamoshita, S., Kawashima, N., Seto, A., Okuno, S., Yamamoto, S., Iwasaki, T., Ozawa, Y., Miyamura, K., Akatsuka, Y. & Sugiura, I., 01-12-2017, : : Medicine (United States). 96, 50, e9160.

研究成果: Article

4 引用 (Scopus)

The prognostic significance of EBV DNA load and EBER status in diagnostic specimens from diffuse large B-cell lymphoma patients

Okamoto, A., Yanada, M., Inaguma, Y., Tokuda, M., Morishima, S., Kanie, T., Yamamoto, Y., Mizuta, S., Akatsuka, Y., Yoshikawa, T., Mizoguchi, Y., Nakamura, S., Okamoto, M. & Emi, N., 01-03-2017, : : Hematological Oncology. 35, 1, p. 87-93 7 p.

研究成果: Article

8 引用 (Scopus)
2016

Clinicopathologic analysis of TAFRO syndrome demonstrates a distinct subtype of HHV-8-negative multicentric Castleman disease

Iwaki, N., Fajgenbaum, D. C., Nabel, C. S., Gion, Y., Kondo, E., Kawano, M., Masunari, T., Yoshida, I., Moro, H., Nikkuni, K., Takai, K., Matsue, K., Kurosawa, M., Hagihara, M., Saito, A., Okamoto, M., Yokota, K., Hiraiwa, S., Nakamura, N., Nakao, S. および2人, Yoshino, T. & Sato, Y., 01-02-2016, : : American Journal of Hematology. 91, 2, p. 220-226 7 p.

研究成果: Article

81 引用 (Scopus)

Development and analysis of patient-derived xenograft mouse models in intravascular large B-cell lymphoma

Shimada, K., Shimada, S., Sugimoto, K., Nakatochi, M., Suguro, M., Hirakawa, A., Hocking, T. D., Takeuchi, I., Tokunaga, T., Takagi, Y., Sakamoto, A., Aoki, T., Naoe, T., Nakamura, S., Hayakawa, F., Seto, M., Tomita, A. & Kiyoi, H., 01-07-2016, : : Leukemia. 30, 7, p. 1568-1579 12 p.

研究成果: Article

9 引用 (Scopus)

Efficacy and safety of febuxostat for prevention of tumor lysis syndrome in patients with malignant tumors receiving chemotherapy: a phase III, randomized, multi-center trial comparing febuxostat and allopurinol

Tamura, K., Kawai, Y., Kiguchi, T., Okamoto, M., Kaneko, M., Maemondo, M., Gemba, K., Fujimaki, K., Kirito, K., Goto, T., Fujisaki, T., Takeda, K., Nakajima, A. & Ueda, T., 01-10-2016, : : International Journal of Clinical Oncology. 21, 5, p. 996-1003 8 p.

研究成果: Article

23 引用 (Scopus)

Erratum: Evaluation of high-throughput genomic assays for the Fc gamma receptor locus (PLoSONE (2015) 10:11 (e0142379))

Hargreaves, C. E., Iriyama, C., Rose-Zerilli, M. J. J., Nagelkerke, S. Q., Hussain, K., Ganderton, R., Lee, C., Machado, L. R., Hollox, E. J., Parker, H., Latham, K. V., Kuijpers, T. W., Potter, K. N., Coupland, S. E., Davies, A., Stackpole, M., Oates, M., Pettitt, A. R., Glennie, M. J., Cragg, M. S. および1人, Strefford, J. C., 03-2016, : : PloS one. 11, 3, e0145040.

研究成果: Comment/debate

公開
1 引用 (Scopus)

ETV6-LPXN fusion transcript generated by t(11;12)(q12.1;p13) in a patient with relapsing acute myeloid leukemia with NUP98-HOXA9

Abe, A., Yamamoto, Y., Iba, S., Kanie, T., Okamoto, A., Tokuda, M., Inaguma, Y., Yanada, M., Morishima, S., Mizuta, S., Akatsuka, Y., Okamoto, M., Kameyama, T., Mayeda, A. & Emi, N., 01-03-2016, : : Genes Chromosomes and Cancer. 55, 3, p. 242-250 9 p.

研究成果: Article

8 引用 (Scopus)
1 引用 (Scopus)
13 引用 (Scopus)

Induction of HLA-B*40:02-restricted T cells possessing cytotoxic and suppressive functions against haematopoietic progenitor cells from a patient with severe aplastic anaemia

Inaguma, Y., Akatsuka, Y., Hosokawa, K., Maruyama, H., Okamoto, A., Katagiri, T., Shiraishi, K., Murayama, Y., Tsuzuki-Iba, S., Mizutani, Y., Nishii, C., Yamamoto, N., Demachi-Okamura, A., Kuzushima, K., Ogawa, S., Emi, N. & Nakao, S., 01-01-2016, : : British Journal of Haematology. 172, 1, p. 131-134 4 p.

研究成果: Article

10 引用 (Scopus)

Influence of R-CHOP therapy on immune system restoration in patients with b-cell lymphoma

Ito, K., Okamoto, M., Inaguma, Y., Okamoto, A., Ando, M., Ando, Y., Tsuge, M., Tomono, A., Kakumae, Y., Hayashi, T., Yamada, S. & Emi, N., 01-11-2016, : : Oncology (Switzerland). 91, 6, p. 302-310 9 p.

研究成果: Article

7 引用 (Scopus)

In vitro antiproliferative activity of 2,3-dihydroxy-9,10-anthraquinone induced apoptosis against COLO320 cells through cytochrome c release caspase mediated pathway with PI3K/AKT and COX-2 inhibition

Balachandran, C., Emi, N., Arun, Y., Yamamoto, N., Duraipandiyan, V., Inaguma, Y., Okamoto, A., Ignacimuthu, S., Al-Dhabi, N. A. & Perumal, P. T., 05-04-2016, : : Chemico-Biological Interactions. 249, p. 23-35 13 p.

研究成果: Article

6 引用 (Scopus)

Isolation and characterization of 2-hydroxy-9,10-anthraquinone from Streptomyces olivochromogenes (ERINLG-261) with antimicrobial and antiproliferative properties

Balachandran, C., Duraipandiyan, V., Arun, Y., Sangeetha, B., Emi, N., Al-Dhabi, N. A., Ignacimuthu, S., Inaguma, Y., Okamoto, A. & Perumal, P. T., 01-05-2016, : : Brazilian Journal of Pharmacognosy. 26, 3, p. 285-295 11 p.

研究成果: Article

10 引用 (Scopus)

Japanese phase II study of rituximab maintenance for untreated indolent B-cell non-Hodgkin lymphoma with high tumor burden

Igarashi, T., Ogura, M., Itoh, K., Taniwaki, M., Ando, K., Kuroda, Y., Yamamoto, K., Uike, N., Tomita, A., Nagai, H., Kurosawa, M., Mori, S., Nawano, S., Terauchi, T., Ohashi, Y. & Tobinai, K., 01-12-2016, : : International Journal of Hematology. 104, 6, p. 700-708 9 p.

研究成果: Article

6 引用 (Scopus)

Live-cell single-molecule imaging of the cytokine receptor MPL for analysis of dynamic dimerization

Sakamoto, A., Tsukamoto, T., Furutani, Y., Sudo, Y., Shimada, K., Tomita, A., Kiyoi, H., Kato, T. & Funatsu, T., 01-01-2016, : : Journal of Molecular Cell Biology. 8, 6, p. 553-555 3 p.

研究成果: Letter

5 引用 (Scopus)

Peripheral blood cell-free DNA is an alternative tumor DNA source reflecting disease status in myelodysplastic syndromes

Suzuki, Y., Tomita, A., Nakamura, F., Iriyama, C., Shirahata-Adachi, M., Shimada, K., Akashi, A., Ishikawa, Y., Kaneda, N. & Kiyoi, H., 01-09-2016, : : Cancer science. 107, 9, p. 1329-1337 9 p.

研究成果: Article

6 引用 (Scopus)

SPIB is a novel prognostic factor in diffuse large B-cell lymphoma that mediates apoptosis via the PI3K-AKT pathway

Takagi, Y., Shimada, K., Shimada, S., Sakamoto, A., Naoe, T., Nakamura, S., Hayakawa, F., Tomita, A. & Kiyoi, H., 01-09-2016, : : Cancer science. 107, 9, p. 1270-1280 11 p.

研究成果: Article

8 引用 (Scopus)

Synthetic investigation on chirally pure Mannich derivatives of pseudophenylpropanolamine and their anticancer properties against HepG-2 cells with inhibition of JAK2/STAT3

Balachandran, C., Chennakesava Rao, K., Arun, Y., Emi, N., Yamamoto, N., Inaguma, Y., Okamoto, A., Easwaramoorthi, K. & Perumal, P. T., 01-01-2016, : : RSC Advances. 6, 99, p. 96946-96962 17 p.

研究成果: Article

6 引用 (Scopus)

TP53 mutations in older adults with acute myeloid leukemia

Yanada, M., Yamamoto, Y., Iba, S., Okamoto, A., Inaguma, Y., Tokuda, M., Morishima, S., Kanie, T., Mizuta, S., Akatsuka, Y., Okamoto, M. & Emi, N., 01-04-2016, : : International Journal of Hematology. 103, 4, p. 429-435 7 p.

研究成果: Article

12 引用 (Scopus)
2015

Discovery of a drug targeting microenvironmental support for lymphoma cells by screening using patient-derived xenograft cells

Sugimoto, K., Hayakawa, F., Shimada, S., Morishita, T., Shimada, K., Katakai, T., Tomita, A., Kiyoi, H. & Naoe, T., 17-08-2015, : : Scientific reports. 5, 13054.

研究成果: Article

18 引用 (Scopus)

Evaluation of the potassium adsorption capacity of a potassium adsorption filter during rapid blood transfusion

Matsuura, H., Akatsuka, Y., Muramatsu, C., Isogai, S., Sugiura, Y., Arakawa, S., Murayama, M., Kurahashi, M., Takasuga, H., Oshige, T., Yuba, T., Mizuta, S. & Emi, N., 01-05-2015, : : Vox Sanguinis. 108, 4, p. 428-431 4 p.

研究成果: Article

4 引用 (Scopus)

Genome-wide surveillance of mismatched alleles for graft-versus-host disease in stem cell transplantation

Sato-Otsubo, A., Nannya, Y., Kashiwase, K., Onizuka, M., Azuma, F., Akatsuka, Y., Ogino, Y., Satake, M., Sanada, M., Chiba, S., Saji, H., Inoko, H., Kennedy, G. C., Yamamoto, K., Morishima, S., Morishima, Y., Kodera, Y., Sasazuki, T. & Ogawa, S., 17-12-2015, : : Blood. 126, 25, p. 2752-2763 12 p.

研究成果: Article

17 引用 (Scopus)

Increased T-cell responses to Epstein-Barr virus with high viral load in patients with Epstein-Barr virus-positive diffuse large B-cell lymphoma

Morishima, S., Nakamura, S., Yamamoto, K., Miyauchi, H., Kagami, Y., Kinoshita, T., Onoda, H., Yatabe, Y., Ito, M., Miyamura, K., Nagai, H., Moritani, S., Sugiura, I., Tsushita, K., Mihara, H., Ohbayashi, K., Iba, S., Emi, N., Okamoto, M., Iwata, S. および3人, Kimura, H., Kuzushima, K. & Morishima, Y., 01-04-2015, : : Leukemia and Lymphoma. 56, 4, p. 1072-1078 7 p.

研究成果: Article

5 引用 (Scopus)