年別の研究成果
年別の研究成果
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2025
Efficacy and Safety of BI 1358894 in Patients With Borderline Personality Disorder: Results of a Phase 2 Randomized, Placebo-Controlled, Parallel Group Dose-Ranging Trial
Dwyer, J. B., Schmahl, C., Makinodan, M., Fineberg, S. K., Sommer, S., Wruck, J., Jelaska, A., Adeniji, A. & Goodman, M., 13-01-2025, In: Diseases of the Nervous System. 86, 1研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
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2024
Association of plasma arachidonic acid levels with a bipolar disorder and the effects of a FADS gene variant
Ashizawa, T., Saito, T., Okochi, T., Ninomiya, K., Ito, K., Aoki, R., Ikeda, M. & Iwata, N., 12-2024, In: Translational psychiatry. 14, 1, 435.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access -
Impacts of adverse childhood experiences on individuals with autism spectrum disorder
Takeda, T., Makinodan, M., Toritsuka, M. & Iwata, N., 12-2024, In: Current Opinion in Neurobiology. 89, 102932.研究成果: ジャーナルへの寄稿 › 総説 › 査読
Open Access -
Reduced prefrontal hemodynamic responses measured using near-infrared spectroscopy in adults with autism spectrum disorder
Kamikawa, K., Yamamuro, K., Mizui, R., Kashida, N., Ishida, R., Okada, T., Iwata, N. & Makinodan, M., 2024, In: Frontiers in Psychiatry. 15, 1507890.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
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Theta burst stimulation for depression: a systematic review and network and pairwise meta-analysis.
Kishi, T., Ikuta, T., Sakuma, K., Hatano, M., Matsuda, Y., Wilkening, J., Goya-Maldonado, R., Tik, M., Williams, N. R., Kito, S. & Iwata, N., 06-06-2024, In: Molecular Psychiatry.研究成果: ジャーナルへの寄稿 › 学術論文
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2023
Differential genetic correlations across major psychiatric disorders between Eastern and Western countries
Saito, T., Ikeda, M., Terao, C., Ashizawa, T., Miyata, M., Tanaka, S., Kanazawa, T., Kato, T., Kishi, T. & Iwata, N., 02-2023, In: Psychiatry and clinical neurosciences. 77, 2, p. 118-119 2 p.研究成果: ジャーナルへの寄稿 › Letter › 査読
Open Access2 被引用数 (Scopus) -
Intermittent theta burst stimulation vs. high-frequency repetitive transcranial magnetic stimulation for major depressive disorder: A systematic review and meta-analysis.
Kishi, T., Sakuma, K., Matsuda, Y., Kito, S. & Iwata, N., 28-08-2023, In: Psychiatry Research. 328, p. 115452-115452 1 p.研究成果: ジャーナルへの寄稿 › 学術論文
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Newer antidepressant for Japanese adults with major depressive disorder: A systematic review and meta-analysis.
Kishi, T., Sakuma, K., Hatano, M., Matsuda, Y., Esumi, S., Miyake, N., Miura, I., Hori, H., Kato, M. & Iwata, N., 30-08-2023, In: Neuropsychopharmacology reports.研究成果: ジャーナルへの寄稿 › 学術論文
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Oral appliance therapy for obstructive sleep apnea: a retrospective study in a psychiatric sleep clinic
Funahashi, K., Hirose, M., Kondo, S., Sano, Y., Fujita, S., Iwata, N. & Kitajima, T., 01-08-2023, In: Fujita Medical Journal. 9, 3, p. 218-224 7 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
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Repetitive transcranial magnetic stimulation for bipolar depression: a systematic review and pairwise and network meta-analysis.
Kishi, T., Ikuta, T., Sakuma, K., Hatano, M., Matsuda, Y., Kito, S. & Iwata, N., 05-04-2023, In: Molecular Psychiatry.研究成果: ジャーナルへの寄稿 › 学術論文
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Repetitive Transcranial Magnetic Stimulation for Mania: A Systematic Review and Meta-analysis.
Kishi, T., Sakuma, K., Matsuda, Y., Kito, S. & Iwata, N., 20-01-2023, In: Bipolar Disorders.研究成果: ジャーナルへの寄稿 › 学術論文
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Repetitive transcranial magnetic stimulation for preventing relapse in antidepressant treatment-resistant depression: A systematic review and meta-analysis of randomized controlled trials.
Matsuda, Y., Sakuma, K., Kishi, T., Esaki, K., Kito, S., Shigeta, M. & Iwata, N., 2023, In: Brain Stimulation. 16, 2, p. 458-461 4 p.研究成果: ジャーナルへの寄稿 › 学術論文
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Safety profile of antidepressant for Japanese adults with major depressive disorder: a systematic review and network meta-analysis.
Kishi, T., Ikuta, T., Sakuma, K., Hatano, M., Matsuda, Y., Esumi, S., Miyake, N., Miura, I., Kato, M. & Iwata, N., 20-11-2023, In: Psychiatry and clinical neurosciences.研究成果: ジャーナルへの寄稿 › 学術論文
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Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions
Brain Somatic Mosaicism Network & Psychiatric Genomic Consortium Schizophrenia and CNV workgroup, 09-08-2023, In: Cell Genomics. 3, 8, 100356.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access13 被引用数 (Scopus) -
Subjective assessment of brexpiprazole in patients with schizophrenia: a prospective observational study
Yokoi, R., Hatano, M., Kamei, H., Morita, A., Hanya, M., Iwata, N. & Yamada, S., 01-08-2023, In: Fujita Medical Journal. 9, 3, p. 231-235 5 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
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Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia
Schizophrenia Working Group of the Psychiatric Genomics Consortium, Stanley Global Asia Initiatives, Psychosis Endophenotypes International Consortium & Wellcome Trust Case Control Consortium, 19-05-2023, In: iScience. 26, 5, 106701.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access2 被引用数 (Scopus) -
2022
Association between long-term alcohol consumption and insomnia symptoms in civil servants: Aichi Workers’ Cohort Study
Terabe, M., Kitajima, T., Ota, A., Yatsuya, H. & Iwata, N., 01-11-2022, In: Fujita Medical Journal. 8, 4, p. 103-107 5 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
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Author Correction: Improving polygenic prediction in ancestrally diverse populations (Nature Genetics, (2022), 54, 5, (573-580), 10.1038/s41588-022-01054-7)
Stanley Global Asia Initiatives, 08-2022, In: Nature Genetics. 54, 8, p. 1259 1 p.研究成果: ジャーナルへの寄稿 › コメント/討論 › 査読
Open Access4 被引用数 (Scopus) -
Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors
Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Eating Disorders Working Group of the Psychiatric Genomics Consortium, German Borderline Genomics Consortium, MVP Suicide Exemplar Workgroup & VA Million Veteran Program, 01-02-2022, In: Biological Psychiatry. 91, 3, p. 313-327 15 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access133 被引用数 (Scopus) -
Improving polygenic prediction in ancestrally diverse populations
Stanley Global Asia Initiatives, 05-2022, In: Nature Genetics. 54, 5, p. 573-580 8 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access235 被引用数 (Scopus) -
Ketoacidosis, Hypertriglyceridemia and Acute Pancreatitis Induced by Soft Drink Polydipsia in a Patient with Occult Central Diabetes Insipidus
Tsujimoto, Y., Nakamura, T., Onishi, J., Ishimaru, N., Iwata, N., Fujisawa, H., Suzuki, A., Sugimura, Y. & Chihara, K., 2022, In: Internal Medicine. 61, 3, p. 365-371 7 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access3 被引用数 (Scopus) -
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
PsychENCODE, Psychosis Endophenotypes International Consortium, The SynGO Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium & Indonesia Schizophrenia Consortium, 21-04-2022, In: Nature. 604, 7906, p. 502-508 7 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access1167 被引用数 (Scopus) -
Relapse and its modifiers in major depressive disorder after antidepressant discontinuation: meta-analysis and meta-regression.
Kishi, T., Sakuma, K., Hatano, M., Okuya, M., Matsuda, Y., Kato, M. & Iwata, N., 23-12-2022, In: Molecular Psychiatry. 28, 3, p. 974-976 3 p.研究成果: ジャーナルへの寄稿 › 学術論文
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Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders
iPSYCH, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium & Sex Differences Cross-Disorder Analysis Group of the Psychiatric Genomics Consortium, 01-01-2022, In: Biological Psychiatry. 91, 1, p. 102-117 16 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access66 被引用数 (Scopus) -
Shared genetic components between metabolic syndrome and schizophrenia: Genetic correlation using multipopulation data sets
Aoki, R., Saito, T., Ninomiya, K., Shimasaki, A., Ashizawa, T., Ito, K., Ikeda, M. & Iwata, N., 08-2022, In: Psychiatry and clinical neurosciences. 76, 8, p. 361-366 6 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access11 被引用数 (Scopus) -
X chromosome aneuploidies and schizophrenia: association analysis and phenotypic characterization
Kushima, I., Aleksic, B., Kimura, H., Nakatochi, M., Lo, T., Ikeda, M., Arai, M., Hashimoto, R., Numata, S., Okamura, Y., Obara, T., Inada, T. & Ozaki, N., 12-2022, In: Psychiatry and clinical neurosciences. 76, 12, p. 667-673 7 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access4 被引用数 (Scopus) -
2021
A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts
Schizophrenia Working Group of the Psychiatric Genomics Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 01-11-2021, In: Biological Psychiatry. 90, 9, p. 611-620 10 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access109 被引用数 (Scopus) -
A polygenic resilience score moderates the genetic risk for schizophrenia
The Schizophrenia Working Group of the Psychiatric Genomics Consortium & Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), 01-03-2021, In: Molecular Psychiatry. 26, 3, p. 800-815 16 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access39 被引用数 (Scopus) -
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
HUNT All-In Psychiatry, 06-2021, In: Nature Genetics. 53, 6, p. 817-829 13 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access710 被引用数 (Scopus) -
Insomnia disorder: clinical and research challenges for the 21st century
the European Sleep Foundation, 07-2021, In: European Journal of Neurology. 28, 7, p. 2156-2167 12 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access33 被引用数 (Scopus) -
2020
Complement genes contribute sex-biased vulnerability in diverse disorders
Schizophrenia Working Group of the Psychiatric Genomics Consortium, Psychosis Endophenotypes International Consortium & Wellcome Trust Case Control Consortium 2, 25-06-2020, In: Nature. 582, 7813, p. 577-581 5 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access166 被引用数 (Scopus) -
Human leukocyte antigen DRB1*04:05 and clozapine-induced agranulocytosis/granulocytopenia
Clozapine Pharmacogenomics Consortium of Japan (CPC-J), 01-05-2020, In: Australian and New Zealand Journal of Psychiatry. 54, 5, p. 545-546 2 p.研究成果: ジャーナルへの寄稿 › Letter › 査読
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Retrospective analysis of the incidence of neurodegenerative disorders in idiopathic rapid eye movement sleep behavior disorder: a preliminary study in Japanese patients
Kumagai, R., Kitajima, T., Hirose, M. & Iwata, N., 2020, In: Fujita Medical Journal. 6, 2, p. 54-58 5 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
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2019
Brexpiprazole as Adjunctive Treatment for Major Depressive Disorder Following Treatment Failure With at Least One Antidepressant in the Current Episode: a Systematic Review and Meta-Analysis
Kishi, T., Sakuma, K., Nomura, I., Matsuda, Y., Mishima, K. & Iwata, N., 01-11-2019, In: The international journal of neuropsychopharmacology. 22, 11, p. 698-709 12 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access12 被引用数 (Scopus) -
Comparative genetic architectures of schizophrenia in East Asian and European populations
Schizophrenia Working Group of the Psychiatric Genomics Consortium, Indonesia Schizophrenia Consortium & Genetic REsearch on schizophreniA neTwork-China and the Netherlands (GREAT-CN), 01-12-2019, In: Nature Genetics. 51, 12, p. 1670-1678 9 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access423 被引用数 (Scopus) -
Gene expression imputation across multiple brain regions provides insights into schizophrenia risk
CommonMind Consortium, The Schizophrenia Working Group of the PsyUniversity of Copenhagenchiatric Genomics Consortium & iPSYCH-GEMS Schizophrenia Working Group, 01-04-2019, In: Nature Genetics. 51, 4, p. 659-674 16 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access134 被引用数 (Scopus) -
Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders
Wellcome Trust Case Control Consortium, Cross-Disorder Group of the Psychiatric Genomics Consortium, 23andMe Research Team & Psychosis Endophenotypes International Consortium, 12-12-2019, In: Cell. 179, 7, p. 1469-1482.e11研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access788 被引用数 (Scopus) -
Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia
Wellcome Trust Case Control Consortium 2 & Schizophrenia Working Group of the Psychiatric Genomics Consortium, 01-04-2019, In: American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 180, 3, p. 223-231 9 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access2 被引用数 (Scopus) -
Publisher Correction: Gene expression imputation across multiple brain regions provides insights into schizophrenia risk (Nature Genetics, (2019), 51, 4, (659-674), 10.1038/s41588-019-0364-4)
CommonMind Consortium, The Schizophrenia Working Group of the Psychiatric Genomics Consortium & iPSYCH-GEMS Schizophrenia Working Group, 01-06-2019, In: Nature Genetics. 51, 6, p. 1068 1 p.研究成果: ジャーナルへの寄稿 › コメント/討論 › 査読
Open Access3 被引用数 (Scopus) -
2018
A correction for sample overlap in genome-wide association studies in a polygenic pleiotropy-informed framework
Schizophrenia and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium, 25-06-2018, In: BMC Genomics. 19, 1, 494.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access29 被引用数 (Scopus) -
A genome-wide association study identifies two novel susceptibility loci and trans population polygenicity associated with bipolar disorder
Advanced Collaborative Study of Mood Disorder (COSMO) team, 01-03-2018, In: Molecular Psychiatry. 23, 3, p. 639-647 9 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access133 被引用数 (Scopus) -
Estimation of Genetic Correlation via Linkage Disequilibrium Score Regression and Genomic Restricted Maximum Likelihood
Wellcome Trust Case Control Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium & Psychosis Endophenotypes International Consortium, 07-06-2018, In: American Journal of Human Genetics. 102, 6, p. 1185-1194 10 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access111 被引用数 (Scopus) -
Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes
Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium [email protected], Psychosis Endophenotypes International Consortium & Wellcome Trust Case Control Consortium, 14-06-2018, In: Cell. 173, 7, p. 1705-1715.e16研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access460 被引用数 (Scopus) -
The genetics of antipsychotic response in schizophrenia
Ikeda, M. & Mushiroda, T., 04-2018, In: The Lancet Psychiatry. 5, 4, p. 291-292 2 p.研究成果: ジャーナルへの寄稿 › コメント/討論 › 査読
4 被引用数 (Scopus) -
Treatment outcome of non-24-hour sleep–wake rhythm disorder: a retrospective study of 24 consecutive cases in a sleep clinic
Hirose, M., Arakawa, C., Watanabe, A., Esaki, Y., Kawai, R., Iwata, N. & Kitajima, T., 2018, In: Fujita Medical Journal. 4, 3, p. 70-76 7 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
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2017
Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects
Psychosis Endophenotypes International Consortium & CNV and Schizophrenia Working Groups of the Psychiatric Genomics Consortium, 01-01-2017, In: Nature Genetics. 49, 1, p. 27-35 9 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access727 被引用数 (Scopus) -
JSNP excellent presentation award for CINP2016
Sugawara, H., Bundo, M., Ikegame, T., Kondo, K., Lkeda, M., Iwata, N., Ishigooka, J., Kasai, K. L., Kato, T. & Iwamoto, K., 06-2017, In: Japanese Journal of Neuropsychopharmacology. 37, 3, p. 81 1 p.研究成果: ジャーナルへの寄稿 › コメント/討論 › 査読
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Transethnic Replication Study to Assess the Association Between Clozapine-Induced Agranulocytosis/Granulocytopenia and Genes at 12p12.2 in a Japanese Population
Members of the Clozapine Pharmacogenomics Consortium of Japan are the following, 01-07-2017, In: Biological Psychiatry. 82, 1, p. e9-e10研究成果: ジャーナルへの寄稿 › Letter › 査読
7 被引用数 (Scopus) -
2016
Erratum: Emerging roles of ARHGAP33 in intracellular trafficking of TrkB and pathophysiology of neuropsychiatric disorders (Nature Communications (2016) 7 (10594) DOI: 10.1038/ncomms10594)
Nakazawa, T., Hashimoto, R., Sakoori, K., Sugaya, Y., Tanimura, A., Hashimotodani, Y., Ohi, K., Yamamori, H., Yasuda, Y., Umeda-Yano, S., Kiyama, Y., Konno, K., Inoue, T., Yokoyama, K., Inoue, T., Numata, S., Ohnuma, T., Iwata, N., Ozaki, N. & Hashimoto, H. & 5 others, , 20-04-2016, In: Nature communications. 7, 11466.研究成果: ジャーナルへの寄稿 › コメント/討論 › 査読
Open Access -
Genetic influences on schizophrenia and subcortical brain volumes: Large-scale proof of concept
Psychosis Endophenotypes International Consortium, 23-02-2016, In: Nature Neuroscience. 19, 3, p. 420-431 12 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access169 被引用数 (Scopus)