研究推進ﾕﾆｯﾄ・ﾚｷﾞｭﾗﾄﾘｰｻｲｴﾝｽ分野

2024

Chronic social defeat stress induces the down-regulation of the Nedd4L-GLT-1 ubiquitination pathway in the prefrontal cortex of mice

Kosuge, A., Kunisawa, K., Iida, T., Wulaer, B., Kawai, T., Tanabe, M., Saito, K., Nabeshima, T. & Mouri, A., 09-2024, In: Journal of neurochemistry. 168, 9, p. 2479-2494 16 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Human metaphase II oocytes with narrow perivitelline space have poor fertilization, developmental, and pregnancy potentials

Shioya, M., Okabe-Kinoshita, M., Kobayashi, T., Fujita, M. & Takahashi, K., 05-2024, In: Journal of Assisted Reproduction and Genetics. 41, 5, p. 1449-1458 10 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

1 被引用数 (Scopus)

Ido2 Deficiency Exacerbates Motor Impairment and Reduces Aryl Hydrocarbon Receptor Activity through Decreased Kynurenine in a Chronic Demyelinating Mouse Model

Kunisawa, K., Hara, M., Yoshidomi, K., Kon, Y., Yamamoto, Y., Fujigaki, S., Wulaer, B., Kosuge, A., Tanabe, M., Saitoh, S., Takahashi, K., Saito, K., Nabeshima, T. & Mouri, A., 2024, (印刷中) In: Molecular Neurobiology.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Indoleamine 2,3-dioxygenase 2 deficiency associates with autism-like behavior via dopaminergic neuronal dysfunction

Ishikawa, M., Yamamoto, Y., Wulaer, B., Kunisawa, K., Fujigaki, H., Ando, T., Kimura, H., Kushima, I., Arioka, Y., Torii, Y., Mouri, A., Ozaki, N., Nabeshima, T. & Saito, K., 03-2024, In: FEBS Journal. 291, 5, p. 945-964 20 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

1 被引用数 (Scopus)

2023

An evaluation method for developing abuse-deterrent opioid formulations with agonist and antagonist combinations using conditioned place preference

Zhang, X., Kitaichi, K., Mouri, A., Zhou, X., Nabeshima, T., Yamada, K. & Nagai, T., 08-01-2023, In: Biochemical and Biophysical Research Communications. 639, p. 100-105 6 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

2 被引用数 (Scopus)

Diagnoses and new therapeutic strategy focused on physiological alteration of tryptophan metabolism

Mouri, A., Hasegawa, M., Kunisawa, K., Saito, K. & Nabeshima, T., 2023, In: Folia Pharmacologica Japonica. 158, 3, p. 233-237 5 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

High salt induces cognitive impairment via the interaction of the angiotensin II-AT₁ and prostaglandin E2-EP₁ systems

Kubota, H., Kunisawa, K., Wulaer, B., Hasegawa, M., Kurahashi, H., Sakata, T., Tezuka, H., Kugita, M., Nagao, S., Nagai, T., Furuyashiki, T., Narumiya, S., Saito, K., Nabeshima, T. & Mouri, A., 09-2023, In: British Journal of Pharmacology. 180, 18, p. 2393-2411 19 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

2 被引用数 (Scopus)

Preface

Ago, Y. & Mouri, A., 2023, In: Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 158, 3, p. 228 1 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Role of MED12 mutation in the pathogenesis of uterine fibroids

Ishikawa, H., Kobayashi, T., Kaneko, M., Saito, Y., Shozu, M. & Koga, K., 11-2023, In: Journal of Molecular Endocrinology. 71, 4, e230039.

研究成果: ジャーナルへの寄稿 › 総説 › 査読

Open Access

2022

Deficiency of kynurenine 3-monooxygenase exacerbates impairment of prepulse inhibition induced by phencyclidine

Kubota, H., Kunisawa, K., Niijima, M., Hirakawa, M., Mori, Y., Hasegawa, M., Fujigaki, S., Fujigaki, H., Yamamoto, Y., Saito, K., Nabeshima, T. & Mouri, A., 12-11-2022, In: Biochemical and Biophysical Research Communications. 629, p. 142-151 10 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

3 被引用数 (Scopus)

Loureirin C and Xanthoceraside Prevent Abnormal Behaviors Associated with Downregulation of Brain Derived Neurotrophic Factor and AKT/mTOR/CREB Signaling in the Prefrontal Cortex Induced by Chronic Corticosterone Exposure in Mice

Yang, Y., Mouri, A., Lu, Q., Kunisawa, K., Kubota, H., Hasegawa, M., Hirakawa, M., Mori, Y., Libo, Z., Saito, K. & Nabeshima, T., 09-2022, In: Neurochemical Research. 47, 9, p. 2865-2879 15 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

9 被引用数 (Scopus)

Phosphoproteomic of the acetylcholine pathway enables discovery of the PKC-β-PIX-Rac1-PAK cascade as a stimulatory signal for aversive learning

Yamahashi, Y., Lin, Y. H., Mouri, A., Iwanaga, S., Kawashima, K., Tokumoto, Y., Watanabe, Y., Faruk, M. O., Zhang, X., Tsuboi, D., Nakano, T., Saito, N., Nagai, T., Yamada, K. & Kaibuchi, K., 08-2022, In: Molecular Psychiatry. 27, 8, p. 3479-3492 14 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

12 被引用数 (Scopus)

Target enrichment long-read sequencing with adaptive sampling can determine the structure of the small supernumerary marker chromosomes

Mariya, T., Kato, T., Sugimoto, T., Miyai, S., Inagaki, H., Ohye, T., Sugihara, E., Muramatsu, Y., Mizuno, S. & Kurahashi, H., 06-2022, In: Journal of Human Genetics. 67, 6, p. 363-368 6 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

10 被引用数 (Scopus)

2021

Coinfection with Human Herpesvirus (HHV)-6B in Immunocompetent, Healthy Individuals with Chromosomally Integrated HHV-6A

Miura, H., Ohye, T., Kozawa, K., Hattori, F., Kawamura, Y., Ihira, M., Kurahashi, H. & Yoshikawa, T., 01-02-2021, In: Journal of the Pediatric Infectious Diseases Society. 10, 2, p. 175-178 4 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

1 被引用数 (Scopus)

Kynurenine 3-monooxygenase deficiency induces depression-like behavior via enhanced antagonism of α7 nicotinic acetylcholine receptors by kynurenic acid

Mori, Y., Mouri, A., Kunisawa, K., Hirakawa, M., Kubota, H., Kosuge, A., Niijima, M., Hasegawa, M., Kurahashi, H., Murakami, R., Hoshi, M., Nakano, T., Fujigaki, S., Fujigaki, H., Yamamoto, Y., Nabeshima, T. & Saito, K., 07-05-2021, In: Behavioural Brain Research. 405, 113191.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

18 被引用数 (Scopus)

Shati/Nat8l deficiency disrupts adult neurogenesis and causes attentional impairment through dopaminergic neuronal dysfunction in the dentate gyrus

Wulaer, B., Kunisawa, K., Hada, K., Jaya Suento, W., Kubota, H., Iida, T., Kosuge, A., Nagai, T., Yamada, K., Nitta, A., Yamamoto, Y., Saito, K., Mouri, A. & Nabeshima, T., 05-2021, In: Journal of neurochemistry. 157, 3, p. 642-655 14 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

14 被引用数 (Scopus)

Tyrosine hydroxylase conditional KO mice reveal peripheral tissue-dependent differences in dopamine biosynthetic pathways

Miyajima, K., Kawamoto, C., Hara, S., Mori-Kojima, M., Ohye, T., Sumi-Ichinose, C., Saito, N., asaoka, T., Metzger, D. & Ichinose, H., 01-01-2021, In: Journal of Biological Chemistry. 296, 100544.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

6 被引用数 (Scopus)

2020

Focal loss of the paranodal domain protein Neurofascin155 in the internal capsule impairs cortically induced muscle activity in vivo

Kunisawa, K., Hatanaka, N., Shimizu, T., Kobayashi, K., Osanai, Y., Mouri, A., Shi, Q., Bhat, M. A., Nambu, A. & Ikenaka, K., 12-2020, In: Molecular brain. 13, 1, 159.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

2 被引用数 (Scopus)

Inherited chromosomally integrated human herpesvirus-6 in a patient with XIAP deficiency

Inoue, K., Miura, H., Hoshino, A., Kamiya, T., Tanita, K., Ohye, T., Park, M. J., Yanagimachi, M., Takagi, M., Imai, K., Morio, T., Yoshikawa, T. & Kanegane, H., 01-10-2020, In: Transplant Infectious Disease. 22, 5, e13331.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

6 被引用数 (Scopus)

Serum Metabolic Profiles of the Tryptophan-Kynurenine Pathway in the high risk subjects of major depressive disorder

Sakurai, M., Yamamoto, Y., Kanayama, N., Hasegawa, M., Mouri, A., Takemura, M., Matsunami, H., Miyauchi, T., Tokura, T., Kimura, H., Ito, M., Umemura, E., Boku, A. S., Nagashima, W., Tonoike, T., Kurita, K., Ozaki, N., Nabeshima, T. & Saito, K., 01-12-2020, In: Scientific reports. 10, 1, 1961.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

50 被引用数 (Scopus)

2019

Acute administration of ketamine attenuates the impairment of social behaviors induced by social defeat stress exposure as juveniles via activation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors

Hasegawa, S., Yoshimi, A., Mouri, A., Uchida, Y., Hida, H., Mishina, M., Yamada, K., Ozaki, N., Nabeshima, T. & Noda, Y., 04-2019, In: Neuropharmacology. 148, p. 107-116 10 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

14 被引用数 (Scopus)

Chronic unpredictable mild stress-induced behavioral changes are coupled with dopaminergic hyperfunction and serotonergic hypofunction in mouse models of depression

Lu, Q., Mouri, A., Yang, Y., Kunisawa, K., Teshigawara, T., Hirakawa, M., Mori, Y., Yamamoto, Y., Libo, Z., Nabeshima, T. & Saito, K., 17-10-2019, In: Behavioural Brain Research. 372, 112053.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

63 被引用数 (Scopus)

Disruption of the responsible gene in a phosphoglucomutase 1 deficiency patient by homozygous chromosomal inversion

Yokoi, K., Nakajima, Y., Ohye, T., Inagaki, H., Wada, Y., Fukuda, T., Sugie, H., Yuasa, I., Ito, T. & Kurahashi, H., 2019, JIMD Reports. Springer, p. 85-90 6 p. (JIMD Reports; vol. 43).

研究成果: 書籍/レポートタイプへの寄稿 › 章

Open Access

9 被引用数 (Scopus)

Indoleamine 2,3-dioxygenase 2 depletion suppresses tumor growth in a mouse model of Lewis lung carcinoma

Yamasuge, W., Yamamoto, Y., Fujigaki, H., Hoshi, M., Nakamoto, K., Kunisawa, K., Mouri, A., Nabeshima, T. & Saito, K., 01-10-2019, In: Cancer science. 110, 10, p. 3061-3067 7 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

22 被引用数 (Scopus)

Linking phencyclidine intoxication to the tryptophan-kynurenine pathway: Therapeutic implications for schizophrenia

Fujigaki, H., Mouri, A., Yamamoto, Y., Nabeshima, T. & Saito, K., 05-2019, In: Neurochemistry International. 125, p. 1-6 6 p.

研究成果: ジャーナルへの寄稿 › 総説 › 査読

22 被引用数 (Scopus)

Selective and competitive inhibition of kynurenine aminotransferase 2 by glycyrrhizic acid and its analogues

Yoshida, Y., Fujigaki, H., Kato, K., Yamazaki, K., Fujigaki, S., Kunisawa, K., Yamamoto, Y., Mouri, A., Oda, A., Nabeshima, T. & Saito, K., 01-12-2019, In: Scientific reports. 9, 1, 10243.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

18 被引用数 (Scopus)

2018

Astroglial major histocompatibility complex class I following immune activation leads to behavioral and neuropathological changes

Sobue, A., Ito, N., Nagai, T., Shan, W., Hada, K., Nakajima, A., Murakami, Y., Mouri, A., Yamamoto, Y., Nabeshima, T., Saito, K. & Yamada, K., 05-2018, In: GLIA. 66, 5, p. 1034-1052 19 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

42 被引用数 (Scopus)

Dysfunction of serotonergic and dopaminergic neuronal systems in the antidepressant-resistant impairment of social behaviors induced by social defeat stress exposure as juveniles

Hasegawa, S., Miyake, Y., Yoshimi, A., Mouri, A., Hida, H., Yamada, K., Ozaki, N., Nabeshima, T. & Noda, Y., 01-09-2018, In: International Journal of Neuropsychopharmacology. 21, 9, p. 837-846 10 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

25 被引用数 (Scopus)

Juvenile social defeat stress exposure persistently impairs social behaviors and neurogenesis

Mouri, A., Ukai, M., Uchida, M., Hasegawa, S., Taniguchi, M., Ito, T., Hida, H., Yoshimi, A., Yamada, K., Kunimoto, S., Ozaki, N., Nabeshima, T. & Noda, Y., 01-05-2018, In: Neuropharmacology. 133, p. 23-37 15 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

48 被引用数 (Scopus)

Lipopolysaccharide shock reveals the immune function of indoleamine 2,3-dioxygenase 2 through the regulation of IL-6/stat3 signalling

Yamamoto, Y., Yamasuge, W., Imai, S., Kunisawa, K., Hoshi, M., Fujigaki, H., Mouri, A., Nabeshima, T. & Saito, K., 01-12-2018, In: Scientific reports. 8, 1, 15917.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

33 被引用数 (Scopus)

Ritanserin, a serotonin-2 receptor antagonist, inhibits functional recovery after cerebral infarction

Mizutani, K., Sonoda, S. & Wakita, H., 03-01-2018, In: Neuroreport. 29, 1, p. 54-58 5 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

6 被引用数 (Scopus)

2017

Absence of kynurenine 3-monooxygenase reduces mortality of acute viral myocarditis in mice

Kubo, H., Hoshi, M., Mouri, A., Tashita, C., Yamamoto, Y., Nabeshima, T. & Saito, K., 01-01-2017, In: Immunology Letters. 181, p. 94-100 7 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

26 被引用数 (Scopus)

JSNP excellent presentation award for CINP2016: Changes of serotonergic functions are mediated via metabolic control of serotonin transporter in stressed Mice

Ito, T., Hida, H., Yamamoto, F., Hasegawa, S., Mouri, A., Ozaki, N. & Noda, Y., 06-2017, In: Japanese Journal of Neuropsychopharmacology. 37, 3, p. 79-80 2 p.

研究成果: ジャーナルへの寄稿 › 簡易調査 › 査読

JSNP excellent presentation award for CINP2016: A strategy for treating in deficits of social behaviors induced by exposure to social defeat stress as juveniles

Hasegawa, S., Miyake, Y., Yoshimi, A. S., Hida, H., Mouri, A., Yamada, K., Ozaki, N., Nabeshima, T. & Noda, Y., 06-2017, In: Japanese Journal of Neuropsychopharmacology. 37, 3, p. 93-94 2 p.

研究成果: ジャーナルへの寄稿 › 簡易調査 › 査読

Kynurenine 3-monooxygenase is implicated in antidepressants-responsive depressive-like behaviors and monoaminergic dysfunctions

Tashiro, T., Murakami, Y., Mouri, A., Imamura, Y., Nabeshima, T., Yamamoto, Y. & Saito, K., 15-01-2017, In: Behavioural Brain Research. 317, p. 279-285 7 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

26 被引用数 (Scopus)

The involvement of brain-derived neurotrophic factor in 3,4-methylenedioxymethamphetamine-induced place preference and behavioral sensitization

Mouri, A., Noda, Y., Niwa, M., Matsumoto, Y., Mamiya, T., Nitta, A., Yamada, K., Furukawa, S., Iwamura, T. & Nabeshima, T., 30-06-2017, In: Behavioural Brain Research. 329, p. 157-165 9 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

12 被引用数 (Scopus)

2016

The ubiquitination of serotonin transporter in lymphoblasts derived from fluvoxamine-resistant depression patients

Mouri, A., Ikeda, M., Koseki, T., Iwata, N. & Nabeshima, T., 23-03-2016, In: Neuroscience Letters. 617, p. 22-26 5 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

10 被引用数 (Scopus)

2015

Nine-year follow-up in a child with chromosomal integration of human herpesvirus 6 transmitted from an unrelated donor through the Japan Marrow Donor Program

Yagasaki, H., Shichino, H., Shimizu, N., Ohye, T., Kurahashi, H., Yoshikawa, T. & Takahashi, S., 01-02-2015, In: Transplant Infectious Disease. 17, 1, p. 160-161 2 p.

研究成果: ジャーナルへの寄稿 › Letter › 査読

4 被引用数 (Scopus)

2014

An immunocompetent child with chromosomally integrated human herpesvirus 6B accidentally identified during the care of Mycoplasma pneumoniae infection

Oikawa, J., Tanaka, J., Yoshikawa, T., Morita, Y., Hishiki, H., Ishiwada, N., Ohye, T., Kurahashi, H. & Kohno, Y., 01-2014, In: Journal of Infection and Chemotherapy. 20, 1, p. 65-67 3 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

4 被引用数 (Scopus)

Changes in serum growth factors in stroke rehabilitation patients and their relation to hemiparesis improvement

Okazaki, H., Beppu, H., Mizutani, K., Okamoto, S. & Sonoda, S., 07-2014, In: Journal of Stroke and Cerebrovascular Diseases. 23, 6, p. 1703-1708 6 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

14 被引用数 (Scopus)

Dual roles for the telomeric repeats in chromosomally integrated human herpesvirus-6

Ohye, T., Inagaki, H., Ihira, M., Higashimoto, Y., Kato, K., Oikawa, J., Yagasaki, H., Niizuma, T., Takahashi, Y., Kojima, S., Yoshikawa, T. & Kurahashi, H., 02-04-2014, In: Scientific reports. 4, 4559.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

23 被引用数 (Scopus)

Molecular and virological evidence of viral activation from chromosomally integrated human herpesvirus 6A in a patient with X-linked severe combined immunodeficiency

Endo, A., Watanabe, K., Ohye, T., Suzuki, K., Matsubara, T., Shimizu, N., Kurahashi, H., Yoshikawa, T., Katano, H., Inoue, N., Imai, K., Takagi, M., Morio, T. & Mizutani, S., 15-08-2014, In: Clinical Infectious Diseases. 59, 4, p. 545-548 4 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

119 被引用数 (Scopus)

Pheochromocytoma as the first manifestation of MEN2A with RET mutation S891A: report of a case

Hibi, Y., Ohye, T., Ogawa, K., Shimizu, Y., Shibata, M., Kagawa, C., Mizuno, Y., Uchino, S., Kosugi, S., Kurahashi, H. & Iwase, K., 11-10-2014, In: Surgery Today. 44, 11, p. 2195-2200 6 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

3 被引用数 (Scopus)

2013

Identification of an enhancer region for immune activation in the human GTP cyclohydrolase i gene

Liang, Y., Inagaki, H., Hao, Q., Sakamoto, M., Ohye, T., Suzuki, T. & Ichinose, H., 06-12-2013, In: Biochemical and Biophysical Research Communications. 442, 1-2, p. 72-78 7 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

2 被引用数 (Scopus)

2012

JSNP Excellent Presentation Award for AsCNP 2011: Combination of a neonatal viral infection with an adolescent substance use affect psychological function in adult

Hida, H., Mouri, A., Taniguchi, M., Ukai, A., Ozaki, N., Yamada, K., Nabeshima, T. & Noda, Y., 04-2012, In: Japanese Journal of Neuropsychopharmacology. 32, 2, p. 101-103 3 p.

研究成果: ジャーナルへの寄稿 › 簡易調査 › 査読

JSNP Excellent Presentation Award for AsCNP 2011: Enriched environment in adolescence prevents abnormal behavior associated with histone deacetylation in phencyclidine-treated mice

Koseki, T., Mouri, A., Mamiya, T., Aoyama, Y., Toriumi, K., Suzuki, S., Nakajima, A., Yamada, T., Nagai, T. & Nabeshima, T., 04-2012, In: Japanese Journal of Neuropsychopharmacology. 32, 2, p. 87-89 3 p.

研究成果: ジャーナルへの寄稿 › 簡易調査 › 査読

2007

Behavioral evaluation in animal models of schizophrenia

Noda, Y., Nabeshima, T. & Mouri, A., 2007, In: Folia Pharmacologica Japonica. 130, 2, p. 117-123 7 p.

研究成果: ジャーナルへの寄稿 › 総説 › 査読

Open Access

Evaluation of latent learning in a water-finding test by using model animals

Mouri, A., Noda, Y. & Nabeshima, T., 2007, In: Folia Pharmacologica Japonica. 130, 2, p. 141-146 6 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

1 被引用数 (Scopus)

2006

Dysfunction of glutamatergic systems and potential animal models of schizophrenia

Mouri, A., Noda, Y., Mizoguchi, H. & Nabeshima, T., 2006, In: Folia Pharmacologica Japonica. 127, 1, p. 4-8 5 p.

研究成果: ジャーナルへの寄稿 › 総説 › 査読

Open Access

1996

A novel strategy for the negative selection in mouse embryonic stem cells operated with immunotoxin-mediated cell targeting

Kobayashi, K., Ohye, T., Pastan, I. & Nagatsu, T., 1996, In: Nucleic acids research. 24, 18, p. 3653-3655 3 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

7 被引用数 (Scopus)

研究推進ﾕﾆｯﾄ・ﾚｷﾞｭﾗﾄﾘｰｻｲｴﾝｽ分野

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