研究支援推進本部

研究成果

2020

2-Nitroimidazoles induce mitochondrial stress and ferroptosis in glioma stem cells residing in a hypoxic niche

Koike, N., Kota, R., Naito, Y., Hayakawa, N., Matsuura, T., Hishiki, T., Onishi, N., Fukada, J., Suematsu, M., Shigematsu, N., Saya, H. & Sampetrean, O., 01-12-2020, : : Communications biology. 3, 1, 450.

研究成果: Article

公開

Aggressive periodontitis and NOD2 variants

Mizuno, N., Kume, K., Nagatani, Y., Matsuda, S., Iwata, T., Ouhara, K., Kajiya, M., Takeda, K., Matsuda, Y., Tada, Y., Ohsawa, R., Morino, H., Mihara, K., Fujita, T., Kawaguchi, H., Shiba, H., Kawakami, H. & Kurihara, H., 2020, (Accepted/In press) : : Journal of Human Genetics. 65, 10, p. 841-846 6 p.

研究成果: Article

A Glimpse of the Peptide Profile Presentation by Xenopus laevis MHC Class I: Crystal structure of PxeLA-UAA reveals a distinct peptide-binding groove

Ma, L., Zhang, N., Qu, Z., Liang, R., Zhang, L., Zhang, B., Meng, G., Dijkstra, J. M., Li, S. & Xia, M. C., 2020, : : Journal of Immunology. 204, 1

研究成果: Article

公開

Analysis of O-glycoforms of the IgA1 hinge region by sequential deglycosylation

Ohyama, Y., Yamaguchi, H., Nakajima, K., Mizuno, T., Fukamachi, Y., Yokoi, Y., Tsuboi, N., Inaguma, D., Hasegawa, M., Renfrow, M. B., Novak, J., Yuzawa, Y. & Takahashi, K., 01-12-2020, : : Scientific reports. 10, 1, 671.

研究成果: Article

公開
1 引用 (Scopus)

A potent blood–brain barrier-permeable mutant IDH1 inhibitor suppresses the growth of glioblastoma with IDH1 mutation in a patient-derived orthotopic xenograft model

Machida, Y., Nakagawa, M., Matsunaga, H., Yamaguchi, M., Ogawara, Y., Shima, Y., Yamagata, K., Katsumoto, T., Hattori, A., Itoh, M., Seki, T., Nishiya, Y., Nakamura, K., Suzuki, K., Imaoka, T., Baba, D., Suzuki, M., Sampetrean, O., Saya, H., Ichimura, K. および1人, Kitabayashi, I., 02-2020, : : Molecular Cancer Therapeutics. 19, 2, p. 375-383 9 p.

研究成果: Article

2 引用 (Scopus)
公開

AUTS2 Regulation of Synapses for Proper Synaptic Inputs and Social Communication

Hori, K., Yamashiro, K., Nagai, T., Shan, W., Egusa, S. F., Shimaoka, K., Kuniishi, H., Sekiguchi, M., Go, Y., Tatsumoto, S., Yamada, M., Shiraishi, R., Kanno, K., Miyashita, S., Sakamoto, A., Abe, M., Sakimura, K., Sone, M., Sohya, K., Kunugi, H. および4人, Wada, K., Yamada, M., Yamada, K. & Hoshino, M., 26-06-2020, : : iScience. 23, 6, 101183.

研究成果: Article

公開

Comparison of physiological and behavioral responses to chronic restraint stress between C57BL/6J and BALB/c mice

Tsuchimine, S., Matsuno, H., O'Hashi, K., Chiba, S., Yoshimura, A., Kunugi, H. & Sohya, K., 23-04-2020, : : Biochemical and Biophysical Research Communications. 525, 1, p. 33-38 6 p.

研究成果: Article

Comprehensive analysis of a novel mouse model of the 22q11.2 deletion syndrome: a model with the most common 3.0-Mb deletion at the human 22q11.2 locus

Saito, R., Koebis, M., Nagai, T., Shimizu, K., Liao, J., Wulaer, B., Sugaya, Y., Nagahama, K., Uesaka, N., Kushima, I., Mori, D., Maruyama, K., Nakao, K., Kurihara, H., Yamada, K., Kano, M., Fukada, Y., Ozaki, N. & Aiba, A., 01-12-2020, : : Translational psychiatry. 10, 1, 35.

研究成果: Article

公開
1 引用 (Scopus)
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Development and characterisation of NKp44-based chimeric antigen receptors that confer T cells with NK cell-like specificity

Kasahara, Y., Shin, C., Kubo, N., Mihara, K., Iwabuchi, H., Takachi, T., Imamura, M., Saitoh, A. & Imai, C., 2020, : : Clinical and Translational Immunology. 9, 7, e1147.

研究成果: Article

公開

Development and evaluation of a novel loop-mediated isothermal amplification (LAMP) method targeting Theileria parasites infecting Yezo sika deer

Shirozu, T., Badolo, A., Soga, A., Yoshimura, A., Morishita, Y. K., Koketsu, M., Shirafuji, R. U., Inokuma, H., Yokoyama, N. & Fukumoto, S., 08-2020, : : Parasitology International. 77, 102130.

研究成果: Article

Development of anti-human CADM1 monoclonal antibodies as a potential therapy for adult T-cell leukemia/lymphoma

Chilmi, S., Nakahata, S., Fauzi, Y. R., Ichikawa, T., Tani, C., Suwanruengsri, M., Yamaguchi, R., Matsuura, T., Kurosawa, G. & Morishita, K., 2020, (Accepted/In press) : : International Journal of Hematology.

研究成果: Article

Differential labeling of glycoproteins with alkynyl fucose analogs

Ma, C., Takeuchi, H., Hao, H., Yonekawa, C., Nakajima, K., Nagae, M., Okajima, T., Haltiwanger, R. S. & Kizuka, Y., 01-09-2020, : : International journal of molecular sciences. 21, 17, p. 1-18 18 p., 6007.

研究成果: Article

公開

Enhanced homologous recombination by the modulation of targeting vector ends

Hirotsune, S., Kiyonari, H., Jin, M., Kumamoto, K., Yoshida, K., Shinohara, M., Watanabe, H., Wynshaw-Boris, A. & Matsuzaki, F., 01-12-2020, : : Scientific reports. 10, 1, 2518.

研究成果: Article

公開

Evaluation of a weighted genetic risk score for the prediction of biomarkers of CYP2A6 activity

El-Boraie, A., Taghavi, T., Chenoweth, M. J., Fukunaga, K., Mushiroda, T., Kubo, M., Lerman, C., Nollen, N. L., Benowitz, N. L. & Tyndale, R. F., 01-01-2020, : : Addiction Biology. 25, 1, e12741.

研究成果: Article

2 引用 (Scopus)
公開
1 引用 (Scopus)
1 引用 (Scopus)

Eye lens dosimetry for workers at Fukushima Daiichi Nuclear Power Plant—2: Field study using humanoid phantoms

Tsujimura, N., Hoshi, K., Aoki, K., Yoshitomi, H., Tanimura, Y. & Yokoyama, S., 06-2020, : : Radiation Measurements. 134, 106305.

研究成果: Article

Full genome characterization of novel DS-1like G9P[8] rotavirus strains that have emerged in Thailand

Fukuda, S., Tacharoenmuang, R., Guntapong, R., Upachai, S., Singchai, P., Ide, T., Hatazawa, R., Sutthiwarakom, K., Kongjorn, S., Onvimala, N., Ruchusatsawast, K., Rungnopakun, P., Mekmallika, J., Kawamura, Y., Motomura, K., Tatsumi, M., Takeda, N., Murata, T., Yoshikawa, T., Uppapong, B. および2人, Taniguchi, K. & Komoto, S., 04-2020, : : PloS one. 15, 4, e0231099.

研究成果: Article

公開
1 引用 (Scopus)

Functional variants in ADH1B and ALDH2 are non-additively associated with all-cause mortality in Japanese population

Sakaue, S., Akiyama, M., Hirata, M., Matsuda, K., Murakami, Y., Kubo, M., Kamatani, Y. & Okada, Y., 01-03-2020, : : European Journal of Human Genetics. 28, 3, p. 378-382 5 p.

研究成果: Article

公開
2 引用 (Scopus)

Generation and analysis of novel Reln-deleted mouse model corresponding to exonic Reln deletion in schizophrenia

Sawahata, M., Mori, D., Arioka, Y., Kubo, H., Kushima, I., Kitagawa, K., Sobue, A., Shishido, E., Sekiguchi, M., Kodama, A., Ikeda, R., Aleksic, B., Kimura, H., Ishizuka, K., Nagai, T., Kaibuchi, K., Nabeshima, T., Yamada, K. & Ozaki, N., 01-05-2020, : : Psychiatry and clinical neurosciences. 74, 5, p. 318-327 10 p.

研究成果: Article

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Gene Therapy Using Neural Stem/Progenitor Cells Derived from Human Induced Pluripotent Stem Cells: Visualization of Migration and Bystander Killing Effect

Tamura, R., Miyoshi, H., Morimoto, Y., Oishi, Y., Sampetrean, O., Iwasawa, C., Mine, Y., Saya, H., Yoshida, K., Okano, H. & Toda, M., 03-2020, : : Human Gene Therapy. 31, 5-6, p. 352-366 15 p.

研究成果: Article

公開

Genome-Wide Natural Selection Signatures Are Linked to Genetic Risk of Modern Phenotypes in the Japanese Population

Yasumizu, Y., Sakaue, S., Konuma, T., Suzuki, K., Matsuda, K., Murakami, Y., Kubo, M., Palamara, P. F., Kamatani, Y. & Okada, Y., 01-05-2020, : : Molecular biology and evolution. 37, 5, p. 1306-1316 11 p.

研究成果: Article

公開

Germline Pathogenic Variants in 7636 Japanese Patients with Prostate Cancer and 12 366 Controls

Momozawa, Y., Iwasaki, Y., Hirata, M., Liu, X., Kamatani, Y., Takahashi, A., Sugano, K., Yoshida, T., Murakami, Y., Matsuda, K., Nakagawa, H., Spurdle, A. B. & Kubo, M., 01-04-2020, : : Journal of the National Cancer Institute. 112, 4, p. 369-376 8 p., djz124.

研究成果: Article

公開
4 引用 (Scopus)

GWAS of 165,084 Japanese individuals identified nine loci associated with dietary habits

Matoba, N., Akiyama, M., Ishigaki, K., Kanai, M., Takahashi, A., Momozawa, Y., Ikegawa, S., Ikeda, M., Iwata, N., Hirata, M., Matsuda, K., Murakami, Y., Kubo, M., Kamatani, Y. & Okada, Y., 01-03-2020, : : Nature Human Behaviour. 4, 3, p. 308-316 9 p.

研究成果: Article

4 引用 (Scopus)

GWAS of five gynecologic diseases and cross-trait analysis in Japanese

Masuda, T., Low, S. K., Akiyama, M., Hirata, M., Ueda, Y., Matsuda, K., Kimura, T., Murakami, Y., Kubo, M., Kamatani, Y. & Okada, Y., 01-01-2020, : : European Journal of Human Genetics. 28, 1, p. 95-107 13 p.

研究成果: Article

公開
3 引用 (Scopus)

High prevalence of equine-like G3P[8] rotavirus in children and adults with acute gastroenteritis in Thailand

Tacharoenmuang, R., Komoto, S., Guntapong, R., Upachai, S., Singchai, P., Ide, T., Fukuda, S., Ruchusatsawast, K., Sriwantana, B., Tatsumi, M., Motomura, K., Takeda, N., Murata, T., Sangkitporn, S., Taniguchi, K. & Yoshikawa, T., 01-02-2020, : : Journal of Medical Virology. 92, 2, p. 174-186 13 p.

研究成果: Article

6 引用 (Scopus)

High Salt Intake Impairs Erectile Function in Salt-Sensitive Rats Through Mineralocorticoid Receptor Pathway Beyond Its Effect on Blood Pressure

Kishimoto, T., Kataoka, T., Yamamoto, Y., Asano, G., Fukamoto, A., Hotta, Y., Maeda, Y., Takahashi, M., Kanayama, H. O. & Kimura, K., 07-2020, : : Journal of Sexual Medicine. 17, 7, p. 1280-1287 8 p.

研究成果: Article

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HLA-B*51:01 and CYP2C9*3 Are Risk Factors for Phenytoin-Induced Eruption in the Japanese Population: Analysis of Data From the Biobank Japan Project

Hikino, K., Ozeki, T., Koido, M., Terao, C., Kamatani, Y., Mizukawa, Y., Shiohara, T., Tohyama, M., Azukizawa, H., Aihara, M., Nihara, H., Morita, E., Murakami, Y., Kubo, M. & Mushiroda, T., 01-05-2020, : : Clinical Pharmacology and Therapeutics. 107, 5, p. 1170-1178 9 p.

研究成果: Article

3 引用 (Scopus)

Identification of kit-ligand a as the gene responsible for the medaka pigment cell mutant few melanophore

Otsuki, Y., Okuda, Y., Naruse, K. & Saya, H., 01-01-2020, : : G3: Genes, Genomes, Genetics. 10, 1, p. 311-319 9 p.

研究成果: Article

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Kynurenine plays an immunosuppressive role in 2,4,6-trinitrobenzene sulfate-induced colitis in mice

Tashita, C., Hoshi, M., Hirata, A., Nakamoto, K., Ando, T., Hattori, T., Yamamoto, Y., Tezuka, H., Tomita, H., Hara, A. & Saito, K., 07-03-2020, : : World Journal of Gastroenterology. 26, 9, p. 918-932 15 p.

研究成果: Article

公開
1 引用 (Scopus)

Measurements of the doses of eye lens for the workers of Fukushima Daiichi Nuclear Power Plant

Yokoyama, S., Ezaki, I., Tatsuzaki, H., Tachiki, S., Hirao, S., Aoki, K., Tanimura, Y., Hoshi, K., Yoshitomi, H. & Tsujimura, N., 11-2020, : : Radiation Measurements. 138, 106399.

研究成果: Article

Mechanism of atopic cataract caused by eosinophil granule major basic protein

Yamamoto, N., Hiramatsu, N., Isogai, S., Kondo, M., Imaizumi, K. & Horiguchi, M., 01-06-2020, : : Medical Molecular Morphology. 53, 2, p. 94-103 10 p.

研究成果: Article

Molecular and cellular mechanisms underlying brain metastasis of breast cancer

Hosonaga, M., Saya, H. & Arima, Y., 01-09-2020, : : Cancer and Metastasis Reviews. 39, 3, p. 711-720 10 p.

研究成果: Review article

公開

Morphological and functional abnormalities of hippocampus in APC 1638T/1638T mice

Li, C., Onouchi, T., Hirayama, M., Sakai, K., Matsuda, S., Yamada, N. O. & Senda, T., 2020, (Accepted/In press) : : Medical Molecular Morphology.

研究成果: Article

Optineurin regulates osteoblastogenesis through STAT1

Mizuno, N., Iwata, T., Ohsawa, R., Ouhara, K., Matsuda, S., Kajiya, M., Matsuda, Y., Kume, K., Tada, Y., Morino, H., Yoshimoto, T., Ueki, Y., Mihara, K., Sotomaru, Y., Takeda, K., Munenaga, S., Fujita, T., Kawaguchi, H., Shiba, H., Kawakami, H. および1人, Kurihara, H., 14-05-2020, : : Biochemical and Biophysical Research Communications. 525, 4, p. 889-894 6 p.

研究成果: Article

Oral intake of α-glucosyl-hesperidin ameliorates selenite-induced cataract formation

Nakazawa, Y., Aoki, M., Ishiwa, S., Morishita, N., Endo, S., Nagai, N., Yamamoto, N., Funakoshi-Tago, M. & Tamura, H., 2020, : : Molecular Medicine Reports. 21, 3, p. 1258-1266 9 p.

研究成果: Article

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Overexpression of a panel of cancer stem cell markers enhances the predictive capability of the progression and recurrence in the early stage cholangiocarcinoma

Padthaisong, S., Thanee, M., Namwat, N., Phetcharaburanin, J., Klanrit, P., Khuntikeo, N., Titapun, A., Sungkhamanon, S., Saya, H. & Loilome, W., 10-02-2020, : : Journal of Translational Medicine. 18, 1, 64.

研究成果: Article

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Phosphorylation of the Anaphase Promoting Complex activator FZR1/CDH1 is required for Meiosis II entry in mouse male germ cell

Tanno, N., Kuninaka, S., Fujimura, S., Takemoto, K., Okamura, K., Takeda, N., Araki, K., Araki, M., Saya, H. & Ishiguro, K. I., 01-12-2020, : : Scientific reports. 10, 1, 10094.

研究成果: Article

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Polygenic risk scores in schizophrenia with clinically significant copy number variants

Taniguchi, S., Ninomiya, K., Kushima, I., Saito, T., Shimasaki, A., Sakusabe, T., Momozawa, Y., Kubo, M., Kamatani, Y., Ozaki, N., Ikeda, M. & Iwata, N., 01-01-2020, : : Psychiatry and clinical neurosciences. 74, 1, p. 35-39 5 p.

研究成果: Article

公開
1 引用 (Scopus)

Preliminary investigation of pretreatment methods for liquid scintillation measurements of environmental water samples using ion exchange resins

Nakasone, S., Yokoyama, S., Takahashi, T., Ota, M., Kakiuchi, H., Sugihara, S., Hirao, S., Momoshima, N., Tamari, T., Shima, N., Atarashi-Andoh, M., Fukutani, S., Ishimine, A., Furukawa, M., Tanaka, M. & Akata, N., 2020, : : Plasma and Fusion Research. 15, SpecialIssue1, 2405027.

研究成果: Article

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Radiolabeled human monoclonal antibody 067-213 has the potential for noninvasive quantification of cd73 expression

Sudo, H., Tsuji, A. B., Sugyo, A., Kurosawa, G., Kurosawa, Y., Alexander, D., Tsuda, H., Saga, T. & Higashi, T., 01-04-2020, : : International journal of molecular sciences. 21, 7, 2304.

研究成果: Article

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Rare primary extramedullary hematopoiesis of the thyroid without intranodular vascularity and mutations in the JAK2, MPL, and calreticulin genes

Matsumura, N., Sasaki, N., Cho, Y., Daimaru, Y., Nojima, T., Mizuno, N., Takei, Y. & Mihara, K., 01-09-2020, : : Annals of Hematology. 99, 9, p. 2211-2213 3 p.

研究成果: Letter

Risk Factors of Infectious Complications After Endobronchial Ultrasound-Guided Transbronchial Biopsy

Souma, T., Minezawa, T., Yatsuya, H., Okamura, T., Yamatsuta, K., Morikawa, S., Horiguchi, T., Maeda, S., Goto, Y., Hayashi, M., Isogai, S., Yamamoto, N., Kondo, M. & Imaizumi, K., 08-2020, : : Chest. 158, 2, p. 797-807 11 p.

研究成果: Article

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3 引用 (Scopus)