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Article
2020

Aggressive periodontitis and NOD2 variants

Mizuno, N., Kume, K., Nagatani, Y., Matsuda, S., Iwata, T., Ouhara, K., Kajiya, M., Takeda, K., Matsuda, Y., Tada, Y., Ohsawa, R., Morino, H., Mihara, K., Fujita, T., Kawaguchi, H., Shiba, H., Kawakami, H. & Kurihara, H., 01-01-2020, (Accepted/In press) : : Journal of Human Genetics.

研究成果: Article

Analysis of O-glycoforms of the IgA1 hinge region by sequential deglycosylation

Ohyama, Y., Yamaguchi, H., Nakajima, K., Mizuno, T., Fukamachi, Y., Yokoi, Y., Tsuboi, N., Inaguma, D., Hasegawa, M., Renfrow, M. B., Novak, J., Yuzawa, Y. & Takahashi, K., 01-12-2020, : : Scientific reports. 10, 1, 671.

研究成果: Article

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An analysis of monocytes and dendritic cells differentiated from human peripheral blood monocyte-derived induced pluripotent stem cells

Hiramatsu, N., Yamamoto, N., Isogai, S., Onouchi, T., Hirayama, M., Maeda, S., Ina, T., Kondo, M. & Imaizumi, K., 01-06-2020, : : Medical Molecular Morphology. 53, 2, p. 63-72 10 p.

研究成果: Article

Comparison of physiological and behavioral responses to chronic restraint stress between C57BL/6J and BALB/c mice

Tsuchimine, S., Matsuno, H., O'Hashi, K., Chiba, S., Yoshimura, A., Kunugi, H. & Sohya, K., 23-04-2020, : : Biochemical and Biophysical Research Communications. 525, 1, p. 33-38 6 p.

研究成果: Article

Development and evaluation of a novel loop-mediated isothermal amplification (LAMP) method targeting Theileria parasites infecting Yezo sika deer

Shirozu, T., Badolo, A., Soga, A., Yoshimura, A., Morishita, Y. K., Koketsu, M., Shirafuji, R. U., Inokuma, H., Yokoyama, N. & Fukumoto, S., 08-2020, : : Parasitology International. 77, 102130.

研究成果: Article

Evaluation of a weighted genetic risk score for the prediction of biomarkers of CYP2A6 activity

El-Boraie, A., Taghavi, T., Chenoweth, M. J., Fukunaga, K., Mushiroda, T., Kubo, M., Lerman, C., Nollen, N. L., Benowitz, N. L. & Tyndale, R. F., 01-01-2020, : : Addiction Biology. 25, 1, e12741.

研究成果: Article

1 引用 (Scopus)

Full genome characterization of novel DS-1like G9P[8] rotavirus strains that have emerged in Thailand

Fukuda, S., Tacharoenmuang, R., Guntapong, R., Upachai, S., Singchai, P., Ide, T., Hatazawa, R., Sutthiwarakom, K., Kongjorn, S., Onvimala, N., Ruchusatsawast, K., Rungnopakun, P., Mekmallika, J., Kawamura, Y., Motomura, K., Tatsumi, M., Takeda, N., Murata, T., Yoshikawa, T., Uppapong, B. および2人, Taniguchi, K. & Komoto, S., 04-2020, : : PloS one. 15, 4, e0231099.

研究成果: Article

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Functional variants in ADH1B and ALDH2 are non-additively associated with all-cause mortality in Japanese population

Sakaue, S., Akiyama, M., Hirata, M., Matsuda, K., Murakami, Y., Kubo, M., Kamatani, Y. & Okada, Y., 01-03-2020, : : European Journal of Human Genetics. 28, 3, p. 378-382 5 p.

研究成果: Article

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1 引用 (Scopus)

Generation and analysis of novel Reln-deleted mouse model corresponding to exonic Reln deletion in schizophrenia

Sawahata, M., Mori, D., Arioka, Y., Kubo, H., Kushima, I., Kitagawa, K., Sobue, A., Shishido, E., Sekiguchi, M., Kodama, A., Ikeda, R., Aleksic, B., Kimura, H., Ishizuka, K., Nagai, T., Kaibuchi, K., Nabeshima, T., Yamada, K. & Ozaki, N., 01-05-2020, : : Psychiatry and clinical neurosciences. 74, 5, p. 318-327 10 p.

研究成果: Article

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Gene Therapy Using Neural Stem/Progenitor Cells Derived from Human Induced Pluripotent Stem Cells: Visualization of Migration and Bystander Killing Effect

Tamura, R., Miyoshi, H., Morimoto, Y., Oishi, Y., Sampetrean, O., Iwasawa, C., Mine, Y., Saya, H., Yoshida, K., Okano, H. & Toda, M., 03-2020, : : Human Gene Therapy. 31, 5-6, p. 352-366 15 p.

研究成果: Article

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Genome-Wide Natural Selection Signatures Are Linked to Genetic Risk of Modern Phenotypes in the Japanese Population

Yasumizu, Y., Sakaue, S., Konuma, T., Suzuki, K., Matsuda, K., Murakami, Y., Kubo, M., Palamara, P. F., Kamatani, Y. & Okada, Y., 01-05-2020, : : Molecular biology and evolution. 37, 5, p. 1306-1316 11 p.

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Germline Pathogenic Variants in 7636 Japanese Patients with Prostate Cancer and 12 366 Controls

Momozawa, Y., Iwasaki, Y., Hirata, M., Liu, X., Kamatani, Y., Takahashi, A., Sugano, K., Yoshida, T., Murakami, Y., Matsuda, K., Nakagawa, H., Spurdle, A. B. & Kubo, M., 01-04-2020, : : Journal of the National Cancer Institute. 112, 4, p. 369-376 8 p., djz124.

研究成果: Article

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4 引用 (Scopus)

GWAS of 165,084 Japanese individuals identified nine loci associated with dietary habits

Matoba, N., Akiyama, M., Ishigaki, K., Kanai, M., Takahashi, A., Momozawa, Y., Ikegawa, S., Ikeda, M., Iwata, N., Hirata, M., Matsuda, K., Murakami, Y., Kubo, M., Kamatani, Y. & Okada, Y., 01-03-2020, : : Nature Human Behaviour. 4, 3, p. 308-316 9 p.

研究成果: Article

3 引用 (Scopus)

GWAS of five gynecologic diseases and cross-trait analysis in Japanese

Masuda, T., Low, S. K., Akiyama, M., Hirata, M., Ueda, Y., Matsuda, K., Kimura, T., Murakami, Y., Kubo, M., Kamatani, Y. & Okada, Y., 01-01-2020, : : European Journal of Human Genetics. 28, 1, p. 95-107 13 p.

研究成果: Article

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1 引用 (Scopus)

High prevalence of equine-like G3P[8] rotavirus in children and adults with acute gastroenteritis in Thailand

Tacharoenmuang, R., Komoto, S., Guntapong, R., Upachai, S., Singchai, P., Ide, T., Fukuda, S., Ruchusatsawast, K., Sriwantana, B., Tatsumi, M., Motomura, K., Takeda, N., Murata, T., Sangkitporn, S., Taniguchi, K. & Yoshikawa, T., 01-02-2020, : : Journal of Medical Virology. 92, 2, p. 174-186 13 p.

研究成果: Article

4 引用 (Scopus)

HLA-B*51:01 and CYP2C9*3 Are Risk Factors for Phenytoin-Induced Eruption in the Japanese Population: Analysis of Data From the Biobank Japan Project

Hikino, K., Ozeki, T., Koido, M., Terao, C., Kamatani, Y., Mizukawa, Y., Shiohara, T., Tohyama, M., Azukizawa, H., Aihara, M., Nihara, H., Morita, E., Murakami, Y., Kubo, M. & Mushiroda, T., 01-05-2020, : : Clinical Pharmacology and Therapeutics. 107, 5, p. 1170-1178 9 p.

研究成果: Article

1 引用 (Scopus)

Identification of kit-ligand a as the gene responsible for the medaka pigment cell mutant few melanophore

Otsuki, Y., Okuda, Y., Naruse, K. & Saya, H., 01-01-2020, : : G3: Genes, Genomes, Genetics. 10, 1, p. 311-319 9 p.

研究成果: Article

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Kynurenine plays an immunosuppressive role in 2,4,6-trinitrobenzene sulfate-induced colitis in mice

Tashita, C., Hoshi, M., Hirata, A., Nakamoto, K., Ando, T., Hattori, T., Yamamoto, Y., Tezuka, H., Tomita, H., Hara, A. & Saito, K., 07-03-2020, : : World Journal of Gastroenterology. 26, 9, p. 918-932 15 p.

研究成果: Article

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1 引用 (Scopus)

Mechanism of atopic cataract caused by eosinophil granule major basic protein

Yamamoto, N., Hiramatsu, N., Isogai, S., Kondo, M., Imaizumi, K. & Horiguchi, M., 01-06-2020, : : Medical Molecular Morphology. 53, 2, p. 94-103 10 p.

研究成果: Article

Optineurin regulates osteoblastogenesis through STAT1

Mizuno, N., Iwata, T., Ohsawa, R., Ouhara, K., Matsuda, S., Kajiya, M., Matsuda, Y., Kume, K., Tada, Y., Morino, H., Yoshimoto, T., Ueki, Y., Mihara, K., Sotomaru, Y., Takeda, K., Munenaga, S., Fujita, T., Kawaguchi, H., Shiba, H., Kawakami, H. および1人, Kurihara, H., 14-05-2020, : : Biochemical and Biophysical Research Communications. 525, 4, p. 889-894 6 p.

研究成果: Article

Oral intake of α-glucosyl-hesperidin ameliorates selenite-induced cataract formation

Nakazawa, Y., Aoki, M., Ishiwa, S., Morishita, N., Endo, S., Nagai, N., Yamamoto, N., Funakoshi-Tago, M. & Tamura, H., 01-01-2020, : : Molecular Medicine Reports. 21, 3, p. 1258-1266 9 p.

研究成果: Article

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Polygenic risk scores in schizophrenia with clinically significant copy number variants

Taniguchi, S., Ninomiya, K., Kushima, I., Saito, T., Shimasaki, A., Sakusabe, T., Momozawa, Y., Kubo, M., Kamatani, Y., Ozaki, N., Ikeda, M. & Iwata, N., 01-01-2020, : : Psychiatry and clinical neurosciences. 74, 1, p. 35-39 5 p.

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Radiolabeled human monoclonal antibody 067-213 has the potential for noninvasive quantification of cd73 expression

Sudo, H., Tsuji, A. B., Sugyo, A., Kurosawa, G., Kurosawa, Y., Alexander, D., Tsuda, H., Saga, T. & Higashi, T., 01-04-2020, : : International journal of molecular sciences. 21, 7, 2304.

研究成果: Article

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Selective accumulation of adiponectin in the cerebral cortex under chronic cerebral hypoperfusion in the rat

Takahashi, Y., Wakita, H., Mizutani, K., Watanabe, A., Sonoda, S. & Tomimoto, H., 27-01-2020, : : Neuroreport. 31, 2, p. 148-155 8 p.

研究成果: Article

The intravitreal injection of lanosterol nanoparticles rescues lens structure collapse at an early stage in shumiya cataract rats

Nagai, N., Fukuoka, Y., Sato, K., Otake, H., Taga, A., Oka, M., Hiramatsu, N. & Yamamoto, N., 01-02-2020, : : International journal of molecular sciences. 21, 3, 1048.

研究成果: Article

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Variants encoding a restricted carboxy-terminal domain of SLC12A2 cause hereditary hearing loss in humans

Mutai, H., Wasano, K., Momozawa, Y., Kamatani, Y., Miya, F., Masuda, S., Morimoto, N., Nara, K., Takahashi, S., Tsunoda, T., Homma, K., Kubo, M. & Matsunaga, T., 04-2020, : : PLoS Genetics. 16, 4, e1008643.

研究成果: Article

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2019
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2 引用 (Scopus)

A genome-wide association study of coping behaviors suggests FBXO45 is associated with emotional expression

Shimanoe, C., Hachiya, T., Hara, M., Nishida, Y., Tanaka, K., Sutoh, Y., Shimizu, A., Hishida, A., Kawai, S., Okada, R., Tamura, T., Matsuo, K., Ito, H., Ozaki, E., Matsui, D., Ibusuki, R., Shimoshikiryo, I., Takashima, N., Kadota, A., Arisawa, K. および12人, Uemura, H., Suzuki, S., Watanabe, M., Kuriki, K., Endoh, K., Mikami, H., Nakamura, Y., Momozawa, Y., Kubo, M., Nakatochi, M., Naito, M. & Wakai, K., 01-02-2019, : : Genes, Brain and Behavior. 18, 2, e12481.

研究成果: Article

4 引用 (Scopus)

Anastrozole Aromatase Inhibitor Plasma Drug Concentration Genome-Wide Association Study: Functional Epistatic Interaction Between SLC38A7 and ALPPL2

Dudenkov, T. M., Liu, D., Cairns, J., Devarajan, S., Zhuang, Y., Ingle, J. N., Buzdar, A. U., Robson, M. E., Kubo, M., Batzler, A., Barman, P., Jenkins, G. D., Carlson, E. E., Goetz, M. P., Northfelt, D. W., Moreno-Aspitia, A., Desta, Z., Reid, J. M., Kalari, K. R., Wang, L. および1人, Weinshilboum, R. M., 01-07-2019, : : Clinical Pharmacology and Therapeutics. 106, 1, p. 219-227 9 p.

研究成果: Article

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1 引用 (Scopus)

An initial genetic analysis of gemcitabine-induced high-grade neutropenia in pancreatic cancer patients in CALGB 80303 (Alliance)

Innocenti, F., Jiang, C., Sibley, A. B., Denning, S., Etheridge, A. S., Watson, D., Niedzwiecki, D., Hatch, A. J., Hurwitz, H. I., Nixon, A. B., Furukawa, Y., Kubo, M., Crona, D. J., Kindler, H. L., McLeod, H. L., Ratain, M. J. & Owzar, K., 01-08-2019, : : Pharmacogenetics and Genomics. 29, 6, p. 123-131 9 p.

研究成果: Article

A novel intragenic deletion in OPHN1 in a Japanese patient with Dandy-Walker malformation

Iida, A., Takeshita, E., Kosugi, S., Kamatani, Y., Momozawa, Y., Kubo, M., Nakagawa, E., Kurosawa, K., Inoue, K. & Goto, Y. I., 01-12-2019, : : Human Genome Variation. 6, 1, 1.

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A Pharmacogenetic Prediction Model of Progression-Free Survival in Breast Cancer using Genome-Wide Genotyping Data from CALGB 40502 (Alliance)

Rashkin, S. R., Chua, K. C., Ho, C., Mulkey, F., Jiang, C., Mushiroda, T., Kubo, M., Friedman, P. N., Rugo, H. S., McLeod, H. L., Ratain, M. J., Castillos, F., Naughton, M., Overmoyer, B., Toppmeyer, D., Witte, J. S., Owzar, K. & Kroetz, D. L., 03-2019, : : Clinical Pharmacology and Therapeutics. 105, 3, p. 738-745 8 p.

研究成果: Article

3 引用 (Scopus)

Association between Genetic Risk and Development of Type 2 Diabetes in a General Japanese Population: The Hisayama Study

Inaishi, J., Hirakawa, Y., Horikoshi, M., Akiyama, M., Higashioka, M., Yoshinari, M., Hata, J., Mukai, N., Kamatani, Y., Momozawa, Y., Kubo, M. & Ninomiya, T., 19-06-2019, : : Journal of Clinical Endocrinology and Metabolism. 104, 8, p. 3213-3222 10 p.

研究成果: Article

3 引用 (Scopus)

Bactericidal/Permeability-Increasing Fold-Containing Family B Member 4 May Be Associated with NSAID-Induced Enteropathy

Fujimori, S., Fukunaga, K., Takahashi, A., Mushiroda, T., Kubo, M., Hanada, R., Hayashida, M., Sakurai, T., Iwakiri, K. & Sakamoto, C., 15-02-2019, : : Digestive Diseases and Sciences. 64, 2, p. 401-408 8 p.

研究成果: Article

Balance between dopamine and adenosine signals regulates the PKA/Rap1 pathway in striatal medium spiny neurons

Zhang, X., Nagai, T., Ahammad, R. U., Kuroda, K., Nakamuta, S., Nakano, T., Yukinawa, N., Funahashi, Y., Yamahashi, Y., Amano, M., Yoshimoto, J., Yamada, K. & Kaibuchi, K., 01-2019, : : Neurochemistry International. 122, p. 8-18 11 p.

研究成果: Article

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2 引用 (Scopus)

Bisecting GlcNAc is a general suppressor of terminal modification of N-glycan

Nakano, M., Mishra, S. K., Tokoro, Y., Sato, K., Nakajima, K., Yamaguchi, Y., Taniguchi, N. & Kizuka, Y., 01-01-2019, : : Molecular and Cellular Proteomics. 18, 10, p. 2044-2057 14 p.

研究成果: Article

4 引用 (Scopus)

Characterization of an unusual DS-1-like G8P[8] rotavirus strain from Japan in 2017: Evolution of emerging DS-1-like G8P[8] strains through reassortment

Kamiya, H., Tacharoenmuang, R., Ide, T., Negoro, M., Tanaka, T., Asada, K., Nakamura, H., Sugiura, K., Umemoto, M., Kuroki, H., Ito, H., Tanaka, S., Ito, M., Fukuda, S., Hatazawa, R., Hara, Y., Guntapong, R., Murata, T., Taniguchi, K., Suga, S. および3人, Nakano, T., Taniguchi, K. & Komoto, S., 01-01-2019, : : Japanese journal of infectious diseases. 72, 4, p. 256-260 5 p.

研究成果: Article

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3 引用 (Scopus)

Clinical and genome-wide analysis of cisplatininduced tinnitus implicates novel ototoxic mechanisms

El Charif, O., Mapes, B., Trendowski, M. R., Wheeler, H. E., Wing, C., Dinh, P. C., Frisina, R. D., Feldman, D. R., Hamilton, R. J., Vaughn, D. J., Fung, C., Kollmannsberger, C., Mushiroda, T., Kubo, M., Gamazon, E. R., Cox, N. J., Huddart, R., Ardeshir-Rouhani-Fard, S., Monahan, P., Fossa, S. D. および3人, Einhorn, L. H., Travis, L. B. & Dolan, M. E., 01-01-2019, : : Clinical Cancer Research. 25, 13, p. 4104-4116 13 p.

研究成果: Article

4 引用 (Scopus)

Clinical and genome-wide analysis of serum platinum levels after cisplatin-based chemotherapy

Trendowski, M. R., El-Charif, O., Ratain, M. J., Monahan, P., Mu, Z., Wheeler, H. E., Dinh, P. C., Feldman, D. R., Ardeshir-Rouhani-Fard, S., Hamilton, R. J., Vaughn, D. J., Fung, C., Kollmannsberger, C., Mushiroda, T., Kubo, M., Hannigan, R., Strathmann, F., Einhorn, L. H., Fossa, S. D., Travis, L. B. および1人, Eileen Dolan, M., 01-10-2019, : : Clinical Cancer Research. 25, 19, p. 5913-5924 12 p.

研究成果: Article

2 引用 (Scopus)
6 引用 (Scopus)

Comparative genetic architectures of schizophrenia in East Asian and European populations

Schizophrenia Working Group of the Psychiatric Genomics Consortium, Indonesia Schizophrenia Consortium & Genetic REsearch on schizophreniA neTwork-China and the Netherlands (GREAT-CN), 01-12-2019, : : Nature Genetics. 51, 12, p. 1670-1678 9 p.

研究成果: Article

17 引用 (Scopus)

Comparison of effects of UGT1A1*6 and UGT1A1*28 on irinotecan-induced adverse reactions in the Japanese population: analysis of the Biobank Japan Project

Hikino, K., Ozeki, T., Koido, M., Terao, C., Kamatani, Y., Murakami, Y., Kubo, M. & Mushiroda, T., 01-12-2019, : : Journal of Human Genetics. 64, 12, p. 1195-1202 8 p.

研究成果: Article

2 引用 (Scopus)

Comprehensive evaluation of structural variation detection algorithms for whole genome sequencing

Kosugi, S., Momozawa, Y., Liu, X., Terao, C., Kubo, M. & Kamatani, Y., 03-06-2019, : : Genome Biology. 20, 1, 117.

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17 引用 (Scopus)

CXCL12 regulates differentiation of human immature melanocyte precursors as well as their migration

Yamada, T., Hasegawa, S., Hasebe, Y., Kawagishi-Hotta, M., Arima, M., Iwata, Y., Kobayashi, T., Numata, S., Yamamoto, N., Nakata, S., Sugiura, K. & Akamatsu, H., 22-01-2019, : : Archives of Dermatological Research. 311, 1, p. 55-62 8 p.

研究成果: Article

Cytohistology of morule in cribriform-morular variant of papillary thyroid carcinoma

Sakurai, K., Onouchi, T., Yamada, S., Baba, Y., Murata, T., Tsukamoto, T., Kuroda, M. & Urano, M., 01-01-2019, : : Malaysian Journal of Pathology. 41, 3, p. 339-343 5 p.

研究成果: Article

Cytokine expression profiles in cervical mucus from patients with cervical cancer and its precursor lesions

Otani, S., Fujii, T., Kukimoto, I., Yamamoto, N., Tsukamoto, T., Ichikawa, R., Nishio, E. & Iwata, A., 08-2019, : : Cytokine. 120, p. 210-219 10 p.

研究成果: Article

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Deep sequencing across germline genome-wide association study signals relating to breast cancer events in women receiving aromatase inhibitors for adjuvant therapy of early breast cancer

Ingle, J. N., Kalari, K. R., Momozawa, Y., Kubo, M., Furukawa, Y., Shepherd, L. E., Ellis, M. J., Goss, P. E., Barman, P., Carlson, E. E., Sinnwell, J. P., Tang, X., Goetz, M. P., Chen, B. E., Cairns, J., Weinshilboum, R. M. & Wang, L., 01-10-2019, : : Pharmacogenetics and genomics. 29, 8, p. 183-191 9 p.

研究成果: Article

Diabetes and cancer risk: A Mendelian randomization study

Goto, A., Yamaji, T., Sawada, N., Momozawa, Y., Kamatani, Y., Kubo, M., Shimazu, T., Inoue, M., Noda, M., Tsugane, S. & Iwasaki, M., 01-01-2019, : : International Journal of Cancer.

研究成果: Article

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4 引用 (Scopus)