医学部

研究成果 1975 2020

1994
41 引用 (Scopus)

Brain activation study by use of positron emission tomography in unanesthetized monkeys

Takechi, H., Onoe, H., Imamura, K., Onoe, K., Kakiuchi, T., Nishiyama, S., Yoshikawa, E., Mori, S., Kosugi, T., Okada, H., Tsukada, H. & Watanabe, Y., 05-12-1994, : : Neuroscience Letters. 182, 2, p. 279-282 4 p.

研究成果: Article

Positron-Emission Tomography
Haplorhini
Cerebrovascular Circulation
Photic Stimulation
Regional Blood Flow
3 引用 (Scopus)

Changes in glial cells in Binswanger-type infarction

Tomimoto, H., Akiguchi, I., Wakita, H. & Kimura, J., 01-01-1994, : : Brain and Nerve. 46, 8, p. 771-779 9 p.

研究成果: Article

Neuroglia
Infarction
Microglia
Astrocytes
Brain Infarction
141 引用 (Scopus)

Clinical features of infants with primary human herpesvirus 6 infection (exanthem subitum, roseola infantum)

Asano, Y., Yoshikawa, T., Suga, S., Kobayashi, I., Nakashima, T., Yazaki, T., Kajita, Y. & Ozaki, T., 01-01-1994, : : Pediatrics. 93, 1, p. 104-108 5 p.

研究成果: Article

Exanthema Subitum
Human Herpesvirus 6
Herpesviridae Infections
Exanthema
Fever
6 引用 (Scopus)

Combined method of mechanical chopper and automated digestion system for islet isolation

Jingu, K., Asano, T., Kenmochi, T., Enomoto, K., Uematsu, T., Nakagohri, T., Tokoro, Y., Matsui, Y., Maruyama, M., Miyauchi, H. & Isono, K., 01-01-1994, : : Transplantation Proceedings. 26, 2, p. 634-636 3 p.

研究成果: Article

Ficoll
Density Gradient Centrifugation
Cell Separation
Automation
Islets of Langerhans
2 引用 (Scopus)

Cryopreservation of fetal porcine proislets using a fully automated cryounit

Miyamoto, M., Kenmochi, T., Nakagawa, Y., Une, S. & Mullen, Y., 01-12-1994, : : Transplantation Proceedings. 26, 6, 1 p.

研究成果: Article

Islets of Langerhans Transplantation
Heterologous Transplantation
C-Peptide
Automation
Cryopreservation

Cystine storage disease (Lignac-Fanconi disease)

Ito, T. & Wada, Y., 1994, : : Ryōikibetsu shōkōgun shirīzu. 4, p. 605-607 3 p.

研究成果: Review article

Cystinosis
Fanconi Syndrome
Differential Diagnosis

Detection of coronary reperfusion using biochemical markers

Ishii, J. & Nomura, M., 07-1994, : : Nippon rinsho. Japanese journal of clinical medicine. 52 Suppl, Pt 1, p. 813-819 7 p.

研究成果: Review article

Neoplasm Proteins
Vascular Patency
Tumor Suppressor Proteins
MB Form Creatine Kinase
Fatty Acid-Binding Proteins
64 引用 (Scopus)

Differential induction of mRNA species encoding several classes of stress proteins following focal cerebral ischemia in rats

Higashi, T., Takechi, H., Uemura, Y., Kikuchi, H. & Nagata, K., 11-07-1994, : : Brain Research. 650, 2, p. 239-248 10 p.

研究成果: Article

Heat-Shock Proteins
Brain Ischemia
Ischemia
Messenger RNA
Physiological Stress
55 引用 (Scopus)

Distribution of nitric oxide synthase in the human cerebral blood vessels and brain tissues

Tomimoto, H., Nishimura, M., Suenaga, T., Nakamura, S., Akiguchi, I., Wakita, H., Kimura, J. & Mayer, B., 11-1994, : : Journal of Cerebral Blood Flow and Metabolism. 14, 6, p. 930-938 9 p.

研究成果: Article

Nitric Oxide Synthase
Blood Vessels
Neurons
NADPH Dehydrogenase
Brain
29 引用 (Scopus)

Early detection of successful coronary reperfusion based on serum myoglobin concentration: Comparison with serum creatine kinase isoenzyme MB activity

Ishii, J., Nomura, M., Ando, T., Hasegawa, H., Kimura, M., Kurokawa, H., Iwase, M., Kondo, T., Watanabe, Y., Hishida, H., Sotohata, I. & Mizuno, Y., 10-1994, : : American Heart Journal. 128, 4, p. 641-648 8 p.

研究成果: Article

MB Form Creatine Kinase
Myocardial Reperfusion
Myoglobin
Isoenzymes
Reperfusion

Effect of amurinone on human pulmonary artery in vitro

Ono, S., Ueda, S., Sakuma, T., Noda, M., Tabata, T., Hoshikawa, Y., Ashino, Y., Tanita, T., Koike, K. & Fujimura, S., 01-01-1994, : : Japanese Journal of Thoracic Diseases. 32, 7, p. 650-654 5 p.

研究成果: Article

Pulmonary Artery
Lung
Vasodilation
Cyclic AMP
Meclofenamic Acid
9 引用 (Scopus)
Phosphoinositide Phospholipase C
Phospholipases A2
Prostaglandins F
Osteoblasts
Dinoprostone
18 引用 (Scopus)

Effect of prostaglandin F on Ca2+ influx in osteoblast‐like cells: Function of tyrosine kinase

Suzuki, A., Kozawa, O., Saito, H. & Oiso, Y., 04-1994, : : Journal of Cellular Biochemistry. 54, 4, p. 487-493 7 p.

研究成果: Article

Dinoprost
Protein-Tyrosine Kinases
Phosphatidylinositols
Hydrolysis
Inositol Phosphates
3 引用 (Scopus)

Effect of retinoic acid on prostaglandin F(2α)-induced prostaglandin E2 synthesis in osteoblast-like cells

Kozawa, O., Suzuki, A., Tokuda, H., Kotoyori, J., Ito, Y. & Oiso, Y., 01-01-1994, : : Hormone and Metabolic Research. 26, 8, p. 374-378 5 p.

研究成果: Article

Osteoblasts
Prostaglandins F
Tretinoin
Dinoprostone
Phospholipases A2
27 引用 (Scopus)

Effect of sepsis on musocal protein synthesis in different parts of the gastrointestinal tract in rats

Higashiguchi, T., Noguchi, Y., O'Brien, W., Wagner, K., Fischer, J. E. & Hasselgren, P. O., 01-01-1994, : : Clinical Science. 87, 2, p. 207-211 5 p.

研究成果: Article

Gastrointestinal Tract
Sepsis
Proteins
Gastric Mucosa
Punctures
4 引用 (Scopus)

Effect of vitamin D3 on prostaglandin E2 synthesis in osteoblast-like cells

Suzuki, A., Tokuda, H., Kotoyori, J., Ito, Y., Oiso, Y. & Kozawa, O., 07-1994, : : Prostaglandins, Leukotrienes and Essential Fatty Acids. 51, 1, p. 27-31 5 p.

研究成果: Article

Dinoprost
Cholecalciferol
Osteoblasts
Dinoprostone
Protein Kinase C
57 引用 (Scopus)

Effects of hemodialysis on cerebral circulation evaluated by transcranial doppler ultrasonography

Hata, R., Matsumoto, M., Handa, N., Terakawa, H., Sugitani, Y. & Kamacta, T., 02-1994, : : Stroke. 25, 2, p. 408-412 5 p.

研究成果: Article

Cerebrovascular Circulation
Doppler Transcranial Ultrasonography
Renal Dialysis
Basilar Artery
Middle Cerebral Artery
1 引用 (Scopus)

Environmental versus Genetic Effects on Serum Levels of High Density Lipoprotein Cholesterol and Apolipoproteins A-I and A-II in the Japanese Fifth Grade Schoolchildren

Toyoshima, H., Hashimoto, S., Miyanishi, K., Hayashi, S., Tanabe, N., Aizaki, T., Satoh, T., Wakai, S. & Fujiwara, M., 01-01-1994, : : Journal of epidemiology. 4, 2, p. 73-82 10 p.

研究成果: Article

Apolipoprotein A-I
HDL Cholesterol
Apolipoproteins A
HDL Lipoproteins
Fathers
17 引用 (Scopus)

Evaluation of regional cerebral blood flow changes on perifocal brain tissue spect before and after removal of arteriovenous malformations

Takeshita, G., Toyama, H., Nakane, K., Nomura, M., Osawa, H., Ogura, Y., Katada, K., Takeuchi, A., Koga, S., Kato, Y., Sano, H. & Kanno, T., 06-1994, : : Nuclear medicine communications. 15, 6, p. 461-468 8 p.

研究成果: Article

Cerebrovascular Circulation
Arteriovenous Malformations
Regional Blood Flow
Perfusion
Single-Photon Emission-Computed Tomography
169 引用 (Scopus)

Experience and reason: Twenty-year follow-up of protective immunity of the Oka strain live varicella vaccine

Asano, Y., Suga, S., Yoshikawa, T., Kobayashi, I., Yazaki, T., Shibata, M., Tsuzuki, K. & Ito, S., 01-01-1994, : : Pediatrics. 94, 4 I, p. 524-526 3 p.

研究成果: Article

Chickenpox Vaccine
Viral Vaccines
Viral Antibodies
Attenuated Vaccines
Human Herpesvirus 3
71 引用 (Scopus)

Fas antigen mRNA induction in postischemic murine brain

Matsuyama, T., Hata, R., Tagaya, M., Yamamoto, Y., Nakajima, T., Furuyama, J. I., Wanaka, A. & Sugita, M., 19-09-1994, : : Brain Research. 657, 1-2, p. 342-346 5 p.

研究成果: Article

CD95 Antigens
Messenger RNA
Brain
Inbred BALB C Mouse
Transient Ischemic Attack
215 引用 (Scopus)
Neuroglia
Brain
Major Histocompatibility Complex
Internal Capsule
Histocompatibility Antigens Class I
19 引用 (Scopus)

Glial conditioned medium alters the expression of amyloid precursor protein in SH-SY5Y neuroblastoma cells

Hirose, Y., Imai, Y., Nakajima, K., Takemoto, N., Toya, S. & Kohsaka, S., 31-01-1994, : : Biochemical and Biophysical Research Communications. 198, 2, p. 504-509 6 p.

研究成果: Article

Amyloid beta-Protein Precursor
Conditioned Culture Medium
Neuroblastoma
Neuroglia
Messenger RNA
13 引用 (Scopus)

Glucocorticoid inhibits cAMP production induced by vasoactive agents in aortic smooth muscle cells

Ito, Y., Kozawa, O., Tokuda, H., Suzuki, A., Watanabe, Y., Kotoyori, J. & Oiso, Y., 30-09-1994, : : Atherosclerosis. 110, 1, p. 69-76 8 p.

研究成果: Article

Dexamethasone
Glucocorticoids
Smooth Muscle Myocytes
Adenylyl Cyclases
Pituitary Adenylate Cyclase-Activating Polypeptide
22 引用 (Scopus)

Histochemical demonstration of membranous localization of endothelial nitric oxide synthase in endothelial cells of the rat brain

Tomimoto, H., Akiguchi, I., Wakita, H., Nakamura, S. & Kimura, J., 19-12-1994, : : Brain Research. 667, 1, p. 107-110 4 p.

研究成果: Article

Nitric Oxide Synthase Type III
Endothelial Cells
Cytoplasmic Vesicles
NADPH Dehydrogenase
Immunoelectron Microscopy
118 引用 (Scopus)

Human ISLET isolation in 104 consecutive cases: Factors affecting isolation success

Benhamou, P. Y., Watt, P. C., Mullen, Y., Ingles, S., Watanabe, Y., Nomura, Y., Hober, C., Miyamoto, M., Kenmochi, T., Passaro, E. P., Zinner, M. J. & Brunicardi, F. C., 07-1994, : : Transplantation. 57, 12, p. 1804-1810 7 p.

研究成果: Article

Collagenases
Blood Glucose
Hospitalization
Cold Ischemia
Islets of Langerhans Transplantation

Hybrid FES orthosis for standing up in Paraplegia

Komiyama, C., Saito, E., Tomita, Y. & Honda, S., 01-01-1994, Conference Proceedings - 10th Anniv., IMTC 1994: Advanced Technologies in I and M. 1994 IEEE Instrumentation and Measurement Technology Conference. Institute of Electrical and Electronics Engineers Inc., p. 575-578 4 p. 351894. (Conference Proceedings - 10th Anniv., IMTC 1994: Advanced Technologies in I and M. 1994 IEEE Instrumentation and Measurement Technology Conference).

研究成果: Conference contribution

stimulation
Muscle
stimuli
Electrodes
Neurology
20 引用 (Scopus)

Identification of risk factors on secondary hyperparathyroidism undergoing long-term haemodialysis with vitamin D3

Mizumoto, D., Watanabe, Y., Fukuzawa, Y., Yuzawa, Y. & Yamazaki, C., 01-01-1994, : : Nephrology Dialysis Transplantation. 9, 12, p. 1751-1758 8 p.

研究成果: Article

Secondary Hyperparathyroidism
Cholecalciferol
Renal Dialysis
Dialysis
Parathyroid Hormone
3 引用 (Scopus)

Immunological tolerance in liver transplantation: The beneficial effect of cytokine down-regulation and Kupffer cell chimerism

Sakurai, H., Mizuno, S., Ohtakura, K., Itoh, F., Machishi, H., Maruyama, A., Higashiguchi, T., Yokoi, H., Noguchi, T., Kawarada, Y. & Mizumoto, R., 01-01-1994, : : Transplantation Proceedings. 26, 2, p. 898-901 4 p.

研究成果: Article

7 引用 (Scopus)

Improved yield and survival of porcine islets with newly developed LAP-1 solution

Kenmochi, T., Miyamoto, M., Nakagawa, Y., Une, S., Benhamou, P. Y. & Mullen, Y., 01-12-1994, : : Transplantation Proceedings. 26, 6, 1 p.

研究成果: Article

Tissue Preservation
Miniature Swine
Cell Separation
Disaccharides
Mannitol
3 引用 (Scopus)

In vivo characteristics of IBZM in rat brains: An agent for quantitative SPECT imaging of D2 dopamine receptors - A basis for semiquantitative measurement of the receptor density using equilibrium analysis

Toyama, H., Matsumura, K., Nakashima, H., Ichise, M., Kurami, M., Nakagawa, T., Maeda, H., Takeuchi, A. & Koga, S., 01-01-1994, : : Kakuigaku. 31, 9, p. 1117-1120 4 p.

研究成果: Article

Dopamine D2 Receptors
Frontal Lobe
Single-Photon Emission-Computed Tomography
Cerebellum
Brain
130 引用 (Scopus)

Localization of the complement regulatory proteins in the normal human kidney

Ichida, S., Yuzawa, Y., Okada, H., Yoshioka, K. & Matsuo, S., 07-1994, : : Kidney International. 46, 1, p. 89-96 8 p.

研究成果: Article

CD46 Antigens
CD59 Antigens
CD55 Antigens
Complement System Proteins
Kidney
1 引用 (Scopus)

Lung 3H-thymidine incorporation in monocrotaline (MCT)-treated rats - Role of platelet-activating factor (PAF)

Ono, S., Tanita, T., Ashino, Y., Noda, M., Tabata, S., Hoshikawa, Y., Ueda, S., Nishimura, T. & Fujimura, S., 01-01-1994, : : Japanese Journal of Thoracic Diseases. 32, 5, p. 441-445 5 p.

研究成果: Article

Monocrotaline
Platelet Activating Factor
Thymidine
Lung
Pulmonary Hypertension
24 引用 (Scopus)

Malaria-induced increase of splenic γδ T cells in humans, monkeys, and mice

Nakazawa, S., Brown, A. E., Maeno, Y., Smith, C. D. & Aikawa, M., 11-1994, : : Experimental Parasitology. 79, 3, p. 391-398 8 p., 71101.

研究成果: Article

Malaria
Haplorhini
T-Lymphocytes
Parasitemia
Spleen
21 引用 (Scopus)

Monoclonal antibody specifically reacting against 73-kilodalton heat shock cognate protein: Possible expression on mammalian cell surface

Tsuboi, N., Ishikawa, M., Tamura, Y., Takayama, S., Tobioka, H., Matsuura, A., Hirayoshi, K., Nagata, K., Sato, N. & Kikuchi, K., 01-01-1994, : : Hybridoma. 13, 5, p. 373-381 9 p.

研究成果: Article

Heat-Shock Proteins
Monoclonal Antibodies
HSP70 Heat-Shock Proteins
B-Lymphocytes
Antigens
4 引用 (Scopus)

Okadaic acid reverses the inhibitory effect of protein kinase C on alkaline phosphatase activity in osteoblast-like cells

Watanabe, Y., Kozawa, O., Suzuki, A., Kotoyori, J., Ito, Y. & Oiso, Y., 07-1994, : : Molecular and Cellular Endocrinology. 103, 1-2, p. 115-118 4 p.

研究成果: Article

Okadaic Acid
Osteoblasts
Protein Kinase C
Alkaline Phosphatase
Serum
12 引用 (Scopus)

Parental origin of 11p15 deletions in human lung cancer

Kondo, M., Suzuki, H., Ueda, R., Takagi, K., Takahashi, T. & Takahashi, T., 01-10-1994, : : Oncogene. 9, 10, p. 3063-3065 3 p.

研究成果: Article

Lung Neoplasms
Alleles
Wilms Tumor
Neoplasms
Loss of Heterozygosity
8 引用 (Scopus)

Phase I study of paclitaxel

Horikoshi, N., Inoue, K., Aiba, K., Mukaiyama, T., Ogihara, A., Sumida, T., Akatsuka, Y., Bessho, A., Inamoto, Y., Uchida, T., Koga, H. & Ogawa, M., 15-11-1994, : : Japanese Journal of Cancer and Chemotherapy. 21, 14, p. 2407-2414 8 p.

研究成果: Article

Paclitaxel
Hypersensitivity
Diphenhydramine
Agranulocytosis
Ranitidine
5 引用 (Scopus)
Viral Antibodies
Human Herpesvirus 3
Acyclovir
Chickenpox
55 引用 (Scopus)

Prostaglandin F activates phospholipase D independently from activation of protein kinase C in osteoblast‐like cells

Kozawa, O., Suzuki, A., Kotoyori, J., Tokuda, H., Watanabe, Y., Ito, Y. & Oiso, Y., 07-1994, : : Journal of Cellular Biochemistry. 55, 3, p. 373-379 7 p.

研究成果: Article

Phospholipase D
Dinoprost
Choline
Protein Kinase C
Chemical activation
10 引用 (Scopus)
Inbred BALB C Mouse
Isogeneic Transplantation
Heterotopic Transplantation
Islets of Langerhans Transplantation
Niacinamide
19 引用 (Scopus)

Radiological quality of coronary guiding catheters: A quantitative analysis

Herrman, JP. R., Keane, D., Ozaki, Y., Boer, A. D. & Serruys, P. W., 09-1994, : : Catheterization and Cardiovascular Diagnosis. 33, 1, p. 55-60 6 p.

研究成果: Article

Catheters
Calibration
Coronary Angiography
Angiography
Atherectomy
8 引用 (Scopus)
Molecular Sequence Data
Antigen Receptors, T-Cell, gamma-delta
Amino Acid Sequence Homology
Conserved Sequence
Amino Acid Sequence
5 引用 (Scopus)

Retrovirus-mediated transfer of a hygromycin phosphotransferase-thymidine kinase fusion gene into human CD34+ bone marrow cells

Akatsuka, Y., Emi, N., Kato, H., Abe, A., Tanimoto, M., Lupton, S. D. & Saito, H., 01-12-1994, : : International Journal of Hematology. 60, 4, p. 251-261 11 p.

研究成果: Article

hygromycin-B kinase
Granulocyte-Macrophage Progenitor Cells
Thymidine Kinase
Gene Fusion
Retroviridae
15 引用 (Scopus)

Sepsis increases production of total secreted proteins, vasoactive intestinal peptide, and peptide YY in isolated rat enterocytes

Higashiguchi, T., Noguchi, Y., Noffsinger, A., Fischer, J. E. & Hasselgren, P. O., 09-1994, : : The American Journal of Surgery. 168, 3, p. 251-256 6 p.

研究成果: Article

Peptide YY
Enterocytes
Vasoactive Intestinal Peptide
Sepsis
Proteins
57 引用 (Scopus)
Rodentia
Inbred Strains Rats
Inbred F344 Rats
Thymocytes
Southern Blotting
19 引用 (Scopus)

Swine as an allotransplantation model

Kenmochi, T., Mullen, Y., Miyamoto, M. & Stein, E., 01-01-1994, : : Veterinary Immunology and Immunopathology. 43, 1-3, p. 177-183 7 p.

研究成果: Article

Transplantation Tolerance
Miniature Swine
graft rejection
miniature swine
bone marrow transplant
44 引用 (Scopus)

Temporal profiles of accumulation of amyloid β/A4 protein precursor in the gerbil after graded ischemic stress

Tomimoto, H., Wakita, H., Akiguchi, I., Nakamura, S. & Kimura, J., 01-01-1994, : : Journal of Cerebral Blood Flow and Metabolism. 14, 4, p. 565-573 9 p.

研究成果: Article

Gerbillinae
Amyloid beta-Protein Precursor
Neurons
Reperfusion
Hippocampus
5 引用 (Scopus)

Temporal variability and correlation with geometric parameters in vasospastic angina: A quantitative angiographic study

Ozaki, Y., Keane, D., Haase, J., Baptista, J., Maneveau, N., de feyter, P. J., Takatsu, F. & Serruys, P. W., 01-1994, : : European Heart Journal. 15, 1, p. 61-67 7 p.

研究成果: Article

Pathologic Constriction
Ergonovine
Vasoconstriction
Coronary Angiography
3 引用 (Scopus)

The granulocyte colony-stimulating factor produced in the human lung and its effect on liquid movement in the rabbit lung

Sakuma, T., Nakada, T., Nishimura, T., Hoshikawa, Y. & Fujimura, S., 01-12-1994, : : Surgery Today. 24, 12, p. 1050-1055 6 p.

研究成果: Article

Granulocyte Colony-Stimulating Factor
Rabbits
Lung
Endothelium
Permeability