医学部

研究成果 1975 2020

1993
6 引用 (Scopus)

Clinical features of primary human herpesvirus-6 infection in an infant with acute lymphoblastic leukemia

Yoshikawa, T., Kobayashi, I., Asano, Y., Nakashima, T., Yazaki, T., Kojima, S. & Yamada, A., 01-01-1993, : : American Journal of Pediatric Hematology/Oncology. 15, 4, p. 424-426 3 p.

研究成果: Article

Human Herpesvirus 6
Herpesviridae Infections
Exanthema
Precursor Cell Lymphoblastic Leukemia-Lymphoma
DNA Viruses
35 引用 (Scopus)

Clonal Analysis of Multiple Point Mutations in the N‐ras Gene in Patients with Acute Myeloid Leukemia

Kubo, K., Naoe, T., Kiyoi, H., Fukutani, H., Kato, Y., Oguri, T., Yamamori, S., Akatsuka, Y., Kodera, Y. & Ohno, R., 04-1993, : : Japanese Journal of Cancer Research. 84, 4, p. 379-387 9 p.

研究成果: Article

Point Mutation
Acute Myeloid Leukemia
Leukemia
Genes
Missense Mutation
47 引用 (Scopus)

Cloning and sequencing of cDNA encoding mouse GTP cyclohydrolase 1

Nomura, T., Ichinose, H., Sumi-Ichinose, C., Nomura, H., Hagino, Y., Fujita, K. & Nagatsu, T., 15-03-1993, : : Biochemical and Biophysical Research Communications. 191, 2, p. 523-527 5 p.

研究成果: Article

GTP Cyclohydrolase
Cloning
Organism Cloning
Complementary DNA
Amino Acids
52 引用 (Scopus)

Differential sequestration of parasitized erythrocytes in the cerebrum and cerebellum in human cerebral malaria

Kyaw Kyaw Sein, K. S., Maeno, Y., Hoang Van Thuc, V. T., Trinh Kim Anh, K. A. & Aikawa, M., 01-01-1993, : : American Journal of Tropical Medicine and Hygiene. 48, 4, p. 504-511 8 p.

研究成果: Article

Cerebral Malaria
Cerebrum
Cerebellum
Erythrocytes
Microvessels
46 引用 (Scopus)

Differential vulnerability in the hindbrain neurons and local cerebral blood flow during bilateral vertebral occlusion in gerbils

Hata, R., Matsumoto, M., Hatakeyama, T., Ohtsuki, T., Handa, N., Niinobe, M., Mikoshiba, K., Sakaki, S., Nishimura, T., Yanagihara, T. & Kamada, T., 09-1993, : : Neuroscience. 56, 2, p. 423-439 17 p.

研究成果: Article

Cerebrovascular Circulation
Rhombencephalon
Gerbillinae
Ischemia
Neurons
23 引用 (Scopus)

Distribution of NADPH-diaphorase in the cerebral blood vessels of rats: a histochemical study

Tomimoto, H., Akiguchi, I., Wakita, H., Nakamura, S. & Kimura, J., 25-06-1993, : : Neuroscience Letters. 156, 1-2, p. 105-108 4 p.

研究成果: Article

NADPH Dehydrogenase
Adventitia
Blood Vessels
Nitric Oxide
Endothelial Cells
22 引用 (Scopus)

Dopamine D2 receptor SPECT imaging: Basic in vivo characteristics and clinical applications of123I-IBZM in humans

Toyama, H., Ichise, M., Ballinger, J. R., Fornazzari, L. & Kirsh, J. C., 01-03-1993, : : Annals of Nuclear Medicine. 7, 1, p. 29-38 10 p.

研究成果: Article

Dopamine D2 Receptors
Frontal Lobe
Basal Ganglia
Single-Photon Emission-Computed Tomography
Huntington Disease
95 引用 (Scopus)

Effect of Glutamine on Protein Synthesis in Isolated Intestinal Epithelial Cells

Higashiguchi, T., Hasselgren, P. O., Wagner, K. & Fischer, J. E., 07-1993, : : Journal of Parenteral and Enteral Nutrition. 17, 4, p. 307-314 8 p.

研究成果: Article

Glutamine
Epithelial Cells
Enterocytes
Proteins
Diazooxonorleucine
1 引用 (Scopus)
Sepsis
Skeletal Muscle
Fibrosis
Amino Acids
Liver
55 引用 (Scopus)

Effect of oral acyclovir against primary and secondary viraemia in incubation period of varicella

Suga, S., Yoshikawa, T., Ozaki, T., Asano, Y. & Conway, S. P., 28-12-1993, : : Archives of Disease in Childhood. 69, 6, p. 639-643 5 p.

研究成果: Article

Acyclovir
Chickenpox
Viremia
Human Herpesvirus 3
Antibodies
30 引用 (Scopus)

Effect of tumor necrosis factor or interleukin-1 on muscle amino acid uptake and the role of glucocorticoids

Zamir, O., Hasselgren, P. O., James, H., Higashiguchi, T. & Fischer, J. E., 01-01-1993, : : Surgery Gynecology and Obstetrics. 177, 1, p. 27-32 6 p.

研究成果: Article

Interleukin-1
Glucocorticoids
Tumor Necrosis Factor-alpha
Amino Acids
Muscles
18 引用 (Scopus)

Exacerbation of idiopathic thrombocytopenic purpura by primary human herpesvirus 6 infection

Yoshikawa, T., Asano, Y., Kobayashi, I., Nakashima, T. & Yazaki, T., 01-01-1993, : : Pediatric Infectious Disease Journal. 12, 5, p. 409-410 2 p.

研究成果: Article

Exanthema Subitum
Human Herpesvirus 6
Herpesviridae Infections
Purpura
Idiopathic Thrombocytopenic Purpura
117 引用 (Scopus)

Experimental validation of geometric and densitometric coronary measurements on the new generation cardiovascular angiography analysis system (caas ii)

Haase, JÜR., Escaned, J., van Swijndregt, E. M., Ozaki, Y., Gronenschild, E., Slager, C. J. & Serruys, P. W., 10-1993, : : Catheterization and Cardiovascular Diagnosis. 30, 2, p. 104-114 11 p.

研究成果: Article

Angiography
Coronary Vessels
Pathologic Constriction
Polymethyl Methacrylate
Swine
32 引用 (Scopus)

Favorable treatment outcome in children with acute myeloid leukemia and Down syndrome [1]

Kojima, S., Kato, K., Matsuyama, T., Yoshikawa, T. & Horibe, K., 01-01-1993, : : Blood. 81, 11, 1 p.

研究成果: Letter

Antineoplastic Combined Chemotherapy Protocols
Leukemia, Megakaryoblastic, Acute
Preschool Children
Down Syndrome
Acute Myeloid Leukemia
11 引用 (Scopus)

Human herpesvirus-6 and parvovirus B19 infections in children

Asano, Y. & Yoshikawa, T., 01-01-1993, : : Current Opinion in Pediatrics. 5, 1, p. 14-20 7 p.

研究成果: Review article

Parvoviridae Infections
Human Herpesvirus 6
Erythema Infectiosum
Human Parvovirus B19
Parvovirus
29 引用 (Scopus)

Immunoglobulin complex deposits in Plasmodium falciparum-infected placentas from Malawi and Papua New Guinea

Maeno, Y., Steketee, R. W., Nagatake, T., Tegoshi, T., Desowitz, R. S., Wirima, J. J. & Aikawa, M., 01-01-1993, : : American Journal of Tropical Medicine and Hygiene. 49, 5, p. 574-580 7 p.

研究成果: Article

Papua New Guinea
Malawi
Plasmodium falciparum
Placenta
Immunoglobulins
21 引用 (Scopus)

Induced resistance and susceptibility to cerebral ischemia in gerbil hippocampal neurons by prolonged but mild hypoperfusion

Ohtsuki, T., Matsumoto, M., Kitagawa, K., Taguchi, A., Maeda, Y., Hata, R., Ogawa, S., Ueda, H., Handa, N. & Kamada, T., 18-06-1993, : : Brain Research. 614, 1-2, p. 279-284 6 p.

研究成果: Article

Gerbillinae
Brain Ischemia
Ischemia
Neurons
HSP72 Heat-Shock Proteins
58 引用 (Scopus)
Dopamine D2 Receptors
Huntington Disease
Technetium
Single-Photon Emission-Computed Tomography
Iodine
9 引用 (Scopus)

Isolation of the Complementary DNA Encoding a Mouse Heparin-binding Growth Factor Receptor with the Use of a Unique Kinase Insert Sequence

Katoh, O., Hattori, Y., Sasaki, H., Sakamoto, H., Fujimoto, K., Fujii, T., Sugimura, T. & Terada, M., 03-1993, : : Cancer Research. 53, 5, p. 1136-1141 6 p.

研究成果: Article

Fibroblast Growth Factor Receptors
Phosphotransferases
Complementary DNA
Proteins
Genes
22 引用 (Scopus)

Long-term follow-up study of 268 diabetic patients undergoing haemodialysis, with special attention to visual acuity and heterogeneity

Watanabe, Y., Yuzawa, Y., Mizumoto, D., Tamai, H., Itoh, Y., Kumon, S. & Yamazaki, C., 01-01-1993, : : Nephrology Dialysis Transplantation. 8, 8, p. 725-734 10 p.

研究成果: Article

Visual Acuity
Chronic Kidney Failure
Renal Dialysis
Macular Edema
Body Fluids
7 引用 (Scopus)
Myeloid Leukemia
Macrophage Colony-Stimulating Factor
G2 Phase
G1 Phase
Myeloid Cells
5 引用 (Scopus)

Mesangial proliferative glomerulonephritis induced in rats by a lentil lectin and its antibodies

Sekiyama, S., Yoshida, F., Yuzawa, Y., Fukatsu, A., Suzuki, N., Sakamoto, N. & Matsuo, S., 01-1993, : : The Journal of Laboratory and Clinical Medicine. 121, 1, p. 71-82 12 p.

研究成果: Article

Glomerulonephritis
Rats
Deposits
Lens Plant
Antibodies
10 引用 (Scopus)

Modulation of prostaglandin E2-induced Ca2+ influx by steroid hormones in osteoblast-like cells

Kozawa, O., Tokuda, H., Kotoyori, J., Suzuki, A., Ito, Y. & Oiso, Y., 09-1993, : : Prostaglandins, Leukotrienes and Essential Fatty Acids. 49, 3, p. 711-714 4 p.

研究成果: Article

Steroid hormones
Osteoblasts
Dinoprostone
Steroids
Modulation
5 引用 (Scopus)

Molecular cloning of cDNA encoding rat homologue of CD5 and CD8α: Evidence that R1-3B3 and R1-10B5 monoclonal antibodies detect rat CD5 and CD8 antigens, respectively

Matsuura, A., Murakami, T., Kozutsumi, D., Kinebuchi, M., Onodera, K., Kon, S. & Kikuchi, K., 01-01-1993, : : Transplantation Proceedings. 25, 5, p. 2793-2794 2 p.

研究成果: Article

Molecular Sequence Data
CD5 Antigens
CD Antigens
CD8 Antigens
Molecular Cloning
3 引用 (Scopus)

Molecular cloning of rat class I genes related to the mouse TL gene subfamily of the major histocompatibility complex

Matsuura, A., Takayama, S., Kozutsumi, D., Ichimiya, S., Honda, R., Shen, M., Natori, T. & Kikuchi, K., 01-01-1993, : : Transplantation Proceedings. 25, 5, p. 2754-2755 2 p.

研究成果: Article

71 引用 (Scopus)

Morphologic effects of artemisinin in Plasmodium falciparum

Maeno, Y., Toyoshima, T., Fujioka, H., Ito, Y., Meshnick, S. R., Benakis, A., Milhous, W. K. & Aikawa, M., 01-01-1993, : : American Journal of Tropical Medicine and Hygiene. 49, 4, p. 485-491 7 p.

研究成果: Article

Plasmodium falciparum
Parasites
dihydroartemisinin
Nuclear Envelope
Vacuoles
21 引用 (Scopus)

Nephrotic syndrome with massive accumulation of type I and type III collagen in the glomeruli

Yoshida, F., Yuzawa, Y., Matsuo, S., Shigematsu, H., Ito, A., Yamazaki, C., Yoshioka, K. & Ooshima, A., 01-01-1993, : : Internal Medicine. 32, 2, p. 171-176 6 p.

研究成果: Article

Collagen Type III
Nephrotic Syndrome
Collagen Type I
Periodic Acid
Collagen Type IV
54 引用 (Scopus)

Nitric Oxide May Upregulate In Vivo Hepatic Protein Synthesis During Endotoxemia

Frederick, J. A., Hasselgren, P. O., Davis, S., Higashiguchi, T., Jacob, T. D. & Fischer, J. E., 02-1993, : : Archives of Surgery. 128, 2, p. 152-157 6 p.

研究成果: Article

Endotoxemia
Nitric Oxide
Up-Regulation
Nitroarginine
Liver
107 引用 (Scopus)

Postexposure prophylaxis of varicella in family contact by oral acyclovir

Asano, Y., Yoshikawa, T., Suga, S., Kobayashi, I., Nakashima, T., Yazaki, T., Ozaki, T., Yamada, A. & Imanishi, J., 01-01-1993, : : Pediatrics. 92, 2 I, p. 219-222 4 p.

研究成果: Article

Acyclovir
Chickenpox
Human Herpesvirus 3
Fever
Oral Administration
5 引用 (Scopus)

Prediction of future trends of HIV infection and AIDS in Japan

Hashimoto, S., Fukutomi, K., Morio, S., Ichikawa, S., Soda, K., Yamamoto, N. & Naemura, M., 10-1993, : : [Nippon kōshū eisei zasshi] Japanese journal of public health. 40, 10, p. 926-933 8 p.

研究成果: Article

HIV Infections
Japan
Acquired Immunodeficiency Syndrome
HIV
30 引用 (Scopus)

Sequestration pattern of parasitized erythrocytes in cerebrum, mid-brain, and cerebellum of Plasmodium coatneyi-infected rhesus monkeys (Macaca mulatta)

Kyaw Kyaw Sein, K. S., Brown, A. E., Maeno, Y., Smith, C. D., Corcoran, K. D., Hansukjariya, P., Webster, H. K. & Aikawa, M., 01-01-1993, : : American Journal of Tropical Medicine and Hygiene. 49, 4, p. 513-519 7 p.

研究成果: Article

Plasmodium
Cerebrum
Macaca mulatta
Cerebellum
Microvessels
79 引用 (Scopus)

Seroepidemiology of human herpesvirus 7 in healthy children and adults in Japan

Yoshikawa, T., Asano, Y., Kobayashi, I., Nakashima, T., Yazaki, T., Suga, S., Ozaki, T., Wyatt, L. S. & Frenkel, N., 01-01-1993, : : Journal of Medical Virology. 41, 4, p. 319-323 5 p.

研究成果: Article

Human Herpesvirus 7
Human Herpesvirus 6
Japan
Antibodies
Saliva
13 引用 (Scopus)

Structural analysis of the CD3 ζ/η locus of the rat: Expression of ζ but not η transcripts by rat T cells

Itoh, Y., Matsuura, A., Kinebuchi, M., Honda, R., Takayama, S., Ichimiya, S., Kon, S. & Kikuchi, K., 01-01-1993, : : Journal of Immunology. 151, 9, p. 4705-4717 13 p.

研究成果: Article

T-Lymphocytes
Peptides
Nucleotides
Frameshift Mutation
Thymocytes
32 引用 (Scopus)

Structure of the gene encoding the mouse 47-kDa heat-shock protein (HSP47)

Nobuko, H., Hajime, T., Shinichi, Y., Kazunori, H. & Kazuhiro, N., 30-04-1993, : : Gene. 126, 2, p. 187-193 7 p.

研究成果: Article

Serine Proteinase Inhibitors
Hot Temperature
Genetic Promoter Regions
Introns
Exons

The administered activity of radionuclides in nuclear medicine. Rational reduction of medical radiation exposure

Nakamura, M., Koga, S., Kondo, T., Tachiki, S., Anno, H., Ejiri, K., Toyama, H., Takeshita, G., Nakane, K., Tokuda, M., Yokoyama, K. & Takeuchi, A., 01-01-1993, : : Kakuigaku. 30, 3, p. 295-301 7 p.

研究成果: Article

Nuclear Medicine
Radioisotopes
Radionuclide Imaging
Inosine Monophosphate
Myocardial Perfusion Imaging
4 引用 (Scopus)

Twenty one multicentral studies on prognosis of advanced ovarian cancer: Focused on correlation between primary surgical procedure following adjuvant chemotherapies and 4 year survival rates

Terashima, Y., Sasaki, H., Yokoyama, S., Ochiai, K., Ueda, K., Yoshikawa, H., Mizutani, K., Yakushiji, M., Nishimura, H., Tsunematsu, R., Tanaka, K., Kodama, S., Takeuchi, S., Yamashita, Y., Namiki, T., Morizuka, T., Mushika, M., Fujii, T. & Hiura, M., 01-01-1993, : : Acta Obstetrica et Gynaecologica Japonica. 45, 4, p. 363-370 8 p.

研究成果: Article

Antineoplastic Combined Chemotherapy Protocols
Ovariectomy
Adjuvant Chemotherapy
Hysterectomy
Ovarian Neoplasms
10 引用 (Scopus)

Varicella‐zoster virus replication site in internal organs of an otherwise healthy child with varicella and sudden death

ASANO, YOSHIZO., YOSHIKAWA, TETSUSHI., URISU, ATSUO., YAZAKI, TAKEHIKO., MIZOGUCHI, YOSHIKAZU. & KURATA, TAKESHI., 08-1993, : : Pediatrics International. 35, 4, p. 348-351 4 p.

研究成果: Article

Chickenpox
Virus Replication
Sudden Death
Viruses
Skin
11 引用 (Scopus)

α1B-Adrenoceptor-mediated stimulation of Ca2+ mobilization and cAMP accumulation in isolated rat hepatocytes

Nomura, T., Kondo, H., Hasegawa, S., Watanabe, T., Yokoyama, R., Ukai, K., Tachibana, M., Ichinose, C., Nomura, H. & Hagino, Y., 15-07-1993, : : European Journal of Pharmacology: Molecular Pharmacology. 246, 2, p. 113-120 8 p.

研究成果: Article

Adrenergic Receptors
Hepatocytes
Norepinephrine
Prazosin
Pertussis Toxin
1994
5 引用 (Scopus)

A case of lung cancer combined with ocular myopathy and idiopathic thrombocytopenic purpura which was presumed to be caused by heart catheterization

Tanita, T., Nishimura, T., Kubo, H., Handa, M., Okada, Y., Hoshikawa, Y., Ueda, S., Shibuya, J., Iwabuchi, S. & Ashino, Y., 04-1994, : : Kyobu geka. The Japanese journal of thoracic surgery. 47, 4, p. 328-331 4 p.

研究成果: Article

Platelet Transfusion
Idiopathic Thrombocytopenic Purpura
gamma-Globulins
Muscular Diseases
Thoracotomy
13 引用 (Scopus)

A case of renal sarcoidosis showing central necrosis and abnormal expression of angiotensin converting enzyme in the granuloma

Ito, Y., Suzuki, T., Mizuno, M., Morita, Y., Muto, E., Ichida, S., Hananouchi, M., Yuzawa, Y. & Matsuo, S., 01-01-1994, : : Clinical nephrology. 42, 5, p. 331-336 6 p.

研究成果: Article

Peptidyl-Dipeptidase A
Sarcoidosis
Granuloma
Necrosis
Kidney
1 引用 (Scopus)

Advantages and Limitations of Intracoronary Ultrasound for the Assessment of Vascular Dimensions

DI MARIO, CARLO., ESCANED‐BARBOSA, JAVIER., BAPTISTA, JOSE., HAASE, JURGEN., OZAKI, YUKIO., ROELANDT, JOS. R. T. C. & SERRUYS, PATRICK. W., 02-1994, : : Journal of Interventional Cardiology. 7, 1, p. 43-56 14 p.

研究成果: Article

Interventional Ultrasonography
Coronary Angiography
Reproducibility of Results
Contrast Media
Calibration
2 引用 (Scopus)

Allogeneic cryopreserved marrow transplantation in a patient with chronic myelogenous leukemia

Akatsuka, Y., Takeshita, T., Tsuzuki, S., Suzuki, R., Sugihara, T., Minami, S. & Kodera, Y., 03-1994, : : [Rinshō ketsueki] The Japanese journal of clinical hematology. 35, 3, p. 304-308 5 p.

研究成果: Article

Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Transplantation
Bone Marrow
Tissue Donors
Glycocalyx
48 引用 (Scopus)

Alternative 5' splice site selection induced by heat shock

Takechi, H., Hosokawa, N., Hirayoshi, K. & Nagata, K., 01-01-1994, : : Molecular and Cellular Biology. 14, 1, p. 567-575 9 p.

研究成果: Article

RNA Splice Sites
Shock
Hot Temperature
Alternative Splicing
Introns

An Evaluation of Stroke Patients in Rehabilitation Medicine

Kimura, A., Chino, N., Saitoh, E., Sonoda, S. & Domen, K., 01-01-1994, : : the keio journal of medicine. 43, 3, p. 143-148 6 p.

研究成果: Article

Rehabilitation
Stroke
Medicine
Rehabilitation Research
8 引用 (Scopus)

A new gerbil model of hindbrain ischemia by extracranial occlusion of the bilateral vertebral arteries

Hata, R., Matsumoto, M., Kitagawa, K., Matsuyama, T., Ohtsuki, T., Tagaya, M., Handa, N., Niinobe, M., Mikoshiba, K., Nishimura, T., Yanagihara, T. & Kamada, T., 01-01-1994, : : Journal of the Neurological Sciences. 121, 1, p. 79-89 11 p.

研究成果: Article

Rhombencephalon
Vertebral Artery
Gerbillinae
Ischemia
Arterial Pressure

An ischemic opening of the blood-brain barrier may deteriorate brain stem auditory evoked potentials following transient hindbrain ischemia in gerbils.

Hata, R., Matsumoto, M., Yamamoto, K., Ohtsuki, T., Ogawa, S., Handa, N., Kubo, T., Matsunaga, T., Nishimura, T. & Kamada, T., 1994, : : Acta neurochirurgica. Supplementum. 60, p. 197-199 3 p.

研究成果: Article

Rhombencephalon
Brain Stem Auditory Evoked Potentials
Gerbillinae
Blood-Brain Barrier
Evans Blue
49 引用 (Scopus)

A nonhuman primate model for human cerebral malaria: Rhesus-monkeys experimentally infected with plasmodium fragile

Fujioka, H., Millet, P., Maeno, Y., Nakazawa, S., Ito, Y., Howard, R. J., Collins, W. E. & Aikawa, M., 06-1994, : : Experimental Parasitology. 78, 4, p. 371-376 6 p., 71040.

研究成果: Article

Cerebral Malaria
Plasmodium
Microvessels
Macaca mulatta
Primates
9 引用 (Scopus)

Anti-oncogene product p53 binds DNA helicase

Sakurai, T., Suzuki, M., Sawazaki, T., Ishii, S. & Yoshida, S., 11-1994, : : Experimental Cell Research. 215, 1, p. 57-62 6 p.

研究成果: Article

DNA Helicases
Oncogene Proteins
Tumor Suppressor Genes
Glutathione Transferase
Glutathione
2 引用 (Scopus)

Bone marrow transplantation from donors other than HLA matched siblings for hematological malignancies. Nagoya Bone Marrow Transplantation Group and Tokai Marrow Donor Bank

Matsumoto, K., Horibe, K., Akatsuka, Y., Minami, S., Matsuyama, T., Hirabayashi, N., Tanimoto, M., Yamada, H., Sobue, R. & Morishima, Y., 08-1994, : : [Rinshō ketsueki] The Japanese journal of clinical hematology. 35, 8, p. 729-737 9 p.

研究成果: Article

Hematologic Neoplasms
Bone Marrow Transplantation
Siblings
Graft vs Host Disease
Bone Marrow
42 引用 (Scopus)

Bone marrow transplant recipients harbor the B variant of human herpesvirus 6

Frenkel, N., Katsafanas, G. C., Wyatt, L. S., Yoshikawa, T. & Asano, Y., 01-12-1994, : : Bone Marrow Transplantation. 14, 5, p. 839-843 5 p.

研究成果: Article

Human Herpesvirus 6
Bone Marrow Transplantation
Bone Marrow
Viremia
Viruses