• 1028 引用
  • 15 h指数
1986 …2017

年単位の研究成果

Pureに変更を加えた場合、すぐここに表示されます。

研究成果

  • 1028 引用
  • 15 h指数
  • 35 Article
  • 2 Chapter
  • 1 Review article
2017

Sepiapterin reductase gene-disrupted mice suffer from hypertension with fluctuation and bradycardia

Sumi-Ichinose, C., Suganuma, Y., Kano, T., Ihira, N., Nomura, H., Ikemoto, K., Hata, T., Katoh, S., Ichinose, H. & Kondo, K., 01-03-2017, : : Physiological Reports. 5, 6, e13196.

研究成果: Article

3 引用 (Scopus)
2014

Disturbed biopterin and folate metabolism in the Qdpr-deficient mouse

Xu, F., Sudo, Y., Sanechika, S., Yamashita, J., Shimaguchi, S., Honda, S. I., Sumi-Ichinose, C., Mori-Kojima, M., Nakata, R., Furuta, T., Sakurai, M., Sugimoto, M., Soga, T., Kondo, K. & Ichinose, H., 03-11-2014, : : FEBS Letters. 588, 21, p. 3924-3931 8 p.

研究成果: Article

11 引用 (Scopus)

Targeted deletion of the C-terminus of the mouse adenomatous polyposis coli tumor suppressor results in neurologic phenotypes related to schizophrenia

Onouchi, T., Kobayashi, K., Sakai, K., Shimomura, A., Smits, R., Sumi-Ichinose, C., Kurosumi, M., Takao, K., Nomura, R., Iizuka-Kogo, A., Suzuki, H., Kondo, K., Akiyama, T., Miyakawa, T., Fodde, R. & Senda, T., 29-03-2014, : : Molecular brain. 7, 1, 21.

研究成果: Article

18 引用 (Scopus)
2013

GTP cyclohydrolase regulation. Implications for brain development and function.

Ichinose, H., Homma, D., Sumi-Ichinose, C., Nomura, T. & Kondo, K., 2013, Advances in Pharmacology. Academic Press Inc., p. 23-35 13 p. (Advances in Pharmacology; 巻数 68).

研究成果: Chapter

2 引用 (Scopus)
2012

Recovery of neurogenic amines in phenylketonuria mice after liver-targeted gene therapy

Yagi, H., Sanechika, S., Ichinose, H., Sumi-Ichinose, C., Mizukami, H., Urabe, M., Ozawa, K. & Kume, A., 04-01-2012, : : NeuroReport. 23, 1, p. 30-34 5 p.

研究成果: Article

7 引用 (Scopus)
2011

Cilostazol inhibits cytokine-induced tetrahydrobiopterin biosynthesis in human umbilical vein endothelial cells.

Shiraishi, H., Ikemoto, K., Tada, S., Udagawa, Y., Ohtsuki, M., Sumi-Ichinose, C., Kondo, K. & Nomura, T., 27-04-2011, : : Journal of atherosclerosis and thrombosis. 18, 4, p. 312-317 6 p.

研究成果: Article

4 引用 (Scopus)

Compensatory regulation of dopamine after ablation of the tyrosine hydroxylase gene in the nigrostriatal projection

Tokuoka, H., Muramatsu, S. I., Sumi-Ichinose, C., Sakane, H., Kojima, M., Aso, Y., Nomura, T., Metzger, D. & Ichinose, H., 16-12-2011, : : Journal of Biological Chemistry. 286, 50, p. 43549-43558 10 p.

研究成果: Article

14 引用 (Scopus)

Partial biopterin deficiency disturbs postnatal development of the dopaminergic system in the brain

Homma, D., Sumi-Ichinose, C., Tokuoka, H., Ikemoto, K., Nomura, T., Kondo, K., Katoh, S. & Ichinose, H., 14-01-2011, : : Journal of Biological Chemistry. 286, 2, p. 1445-1452 8 p.

研究成果: Article

17 引用 (Scopus)
2010
9 引用 (Scopus)
2009

Nurr1 is required for maintenance of maturing and adult midbrain dopamine neurons

Kadkhodaei, B., Ito, T., Joodmardi, E., Mattsson, B., Rouillard, C., Carta, M., Muramatsu, S. I., Sumi-Ichinose, C., Nomura, T., Metzger, D., Chambon, P., Lindqvist, E., Larsson, N. G., Olson, L., Björklund, A., Ichinose, H. & Perlmann, T., 16-12-2009, : : Journal of Neuroscience. 29, 50, p. 15923-15932 10 p.

研究成果: Article

219 引用 (Scopus)
2008

2,4-Diamino-6-hydroxypyrimidine (DAHP) suppresses cytokine-induced VCAM-1 expression on the cell surface of human umbilical vein endothelial cells in a BH4-independent manner

Ikemoto, K., Matsumoto, T., Ohtsuki, M., Itoh, M., Tada, S., Udagawa, Y., Sumi-Ichinose, C., Kondo, K. & Nomura, T., 01-07-2008, : : Biochimica et Biophysica Acta - General Subjects. 1780, 7-8, p. 960-965 6 p.

研究成果: Article

4 引用 (Scopus)

A brain-specific decrease of the tyrosine hydroxylase protein in sepiapterin reductase-null mice-as a mouse model for Parkinson's disease

Takazawa, C., Fujimoto, K., Homma, D., Sumi-Ichinose, C., Nomura, T., Ichinose, H. & Katoh, S., 21-03-2008, : : Biochemical and Biophysical Research Communications. 367, 4, p. 787-792 6 p.

研究成果: Article

24 引用 (Scopus)

Differential involvement of striosome and matrix dopamine systems in a transgenic model of dopa-responsive dystonia

Sato, K., Sumi-Ichinose, C., Kaji, R., Ikemoto, K., Nomura, T., Nagatsu, I., Ichinose, H., Ito, M., Sako, W., Nagahiro, S., Graybiel, A. M. & Goto, S., 26-08-2008, : : Proceedings of the National Academy of Sciences of the United States of America. 105, 34, p. 12551-12556 6 p.

研究成果: Article

61 引用 (Scopus)

Increased expression of tyrosine hydroxylase and anomalous neurites in catecholaminergic neurons of ATF-2 null mice

Kojima, M., Suzuki, T., Maekawa, T., Ishii, S., Sumi-Ichinose, C., Nomura, T. & Ichinose, H., 15-02-2008, : : Journal of Neuroscience Research. 86, 3, p. 544-552 9 p.

研究成果: Article

3 引用 (Scopus)

Metabolism of tetrahydrobiopterin: Its relevance in monoaminergic neurons and neurological disorders

Ichinose, H., Nomura, T. & Ichinose, C., 01-12-2008, : : Chemical Record. 8, 6, p. 378-385 8 p.

研究成果: Article

13 引用 (Scopus)
2005

Genetically rescued tetrahydrobiopterin-depleted mice survive with hyperphenylalaninemia and region-specific monoaminergic abnormalities

Sumi-Ichinose, C., Urano, F., Shimomura, A., Sato, T., Ikemoto, K., Shiraishi, H., Senda, T., Ichinose, H. & Nomura, T., 14-11-2005, : : Journal of Neurochemistry. 95, 3, p. 703-714 12 p.

研究成果: Article

19 引用 (Scopus)
2003

cGMP inhibits GTP cyclohydrolase I activity and biosynthesis of tetrahydrobiopterin in human umbilical vein endothelial cells

Shiraishi, H., Kato, T., Atsuta, K., Sumi-Ichinose, C., Ohtsuki, M., Itoh, M., Hishida, H., Tada, S., Udagawa, Y., Nagatsu, T., Hagino, Y., Ichinose, H. & Nomura, T., 01-11-2003, : : Journal of Pharmacological Sciences. 93, 3, p. 265-271 7 p.

研究成果: Article

7 引用 (Scopus)

Dopa-Responsive Dystonia

Ichinose, H., Nagatsu, T., Ichinose, C. & Nomura, T., 01-01-2003, Genetics of Movement Disorders. Elsevier Inc., p. 419-428 10 p.

研究成果: Chapter

1 引用 (Scopus)
2002

cAMP inhibits cytokine-induced biosynthesis of tetrahydrobiopterin in human umbilical vein endothelial cells

Ohtsuki, M., Shiraishi, H., Kato, T., Kuroda, R., Tazawa, M., Sumi-Ichinose, C., Tada, S., Udagawa, Y., Itoh, M., Hishida, H., Ichinose, H., Nagatsu, T., Hagino, Y. & Nomura, T., 22-03-2002, : : Life Sciences. 70, 18, p. 2187-2198 12 p.

研究成果: Article

7 引用 (Scopus)
2001

Catecholamines and serotonin are differently regulated by tetrahydrobiopterin. A study from 6-pyruvoyltetrahydropterin synthase knockout mice

Sumi-Ichinose, C., Urano, F., Kuroda, R., Ohye, T., Kojima, M., Tazawa, M., Shiraishi, H., Hagino, Y., Nagatsu, T., Nomura, T. & Ichinose, H., 02-11-2001, : : Journal of Biological Chemistry. 276, 44, p. 41150-41160 11 p.

研究成果: Article

106 引用 (Scopus)

Perspectives on tetrahydrobiopterin research

Sumi-Ichinose, C., Ohtsuki, M., Shiraishi, H. & Nomura, T., 29-12-2001, : : Folia Pharmacologica Japonica. 118, 6, p. 371-377 7 p.

研究成果: Review article

2 引用 (Scopus)
2000

Effects of sulfhydryl reagents on nitric oxide release from a nitric oxide donor NOR 3 in the presence of rat hepatocytes

Nomura, H., Tazawa, M., Kuroda, R., Shiraishi, H., Sumi-Ichinose, C., Matsui, S., Ohtsuki, M., Hagino, Y. & Nomura, T., 11-2000, : : Pharmacology and Toxicology. 87, 5, p. 246-248 3 p.

研究成果: Article

GTP cyclohydrolase I from Tetrahymena pyriformis: Cloning of cDNA and expression

Tazawa, M., Ohtsuki, M., Sumi-Ichinose, C., Shiraishi, H., Kuroda, R., Hagino, Y., Nakashima, S., Nozawa, Y., Ichinose, H., Nagatsu, T. & Nomura, T., 01-09-2000, : : Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology. 127, 1, p. 65-73 9 p.

研究成果: Article

4 引用 (Scopus)
1999

Molecular cloning of the human Nurr1 gene: Characterization of the human gene and cDNAs

Ichinose, H., Ohye, T., Suzuki, T., Sumi-Ichinose, C., Nomura, T., Hagino, Y. & Nagatsu, T., 16-04-1999, : : Gene. 230, 2, p. 233-239 7 p.

研究成果: Article

45 引用 (Scopus)
1998

Enzymes related to catecholamine biosynthesis in Tetrahymena pyriformis. Presence of GTP cyclohydrolase I

Nomura, T., Tazawa, M., Ohtsuki, M., Sumi-Ichinose, C., Hagino, Y., Ota, A., Nakashima, A., Mori, K., Sugimoto, T., Ueno, O., Nozawa, Y., Ichinose, H. & Nagatsu, T., 01-01-1998, : : Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology. 120, 4, p. 753-760 8 p.

研究成果: Article

10 引用 (Scopus)

Nitric oxide donor NOR 3 inhibits ketogenesis from oleate in isolated rat hepatocytes by a cyclic GMP-independent mechanism

Nomura, T., Ohtsuki, M., Matsui, S., Sumi-Ichinose, C., Nomura, H. & Hagino, Y., 01-01-1998, : : Pharmacology and Toxicology. 82, 1, p. 40-46 7 p.

研究成果: Article

7 引用 (Scopus)
1997

SNF2β-BRG1 is essential for the viability of F9 murine embryonal carcinoma cells

Sumi-Ichinose, C., Ichinose, H., Metzger, D. & Chambon, P., 01-10-1997, : : Molecular and Cellular Biology. 17, 10, p. 5976-5986 11 p.

研究成果: Article

123 引用 (Scopus)
1996

Analysis of an alternative promoter that regulates tissue-specific expression of the human aromatic L-amino acid decarboxylase gene in cultured cell lines

Sumi-Ichinose, C., Hasegawa, S., Ohtsuki, M., Nomura, H., Nomura, T., Hagino, Y., Fujita, K. & Nagatsu, T., 01-01-1996, : : Journal of Neural Transmission. 103, 1-2, p. 1-15 15 p.

研究成果: Article

3 引用 (Scopus)
1995

Analysis of the Alternative Promoters that Regulate Tissue‐Specific Expression of Human Aromatic l‐Amino Acid Decarboxylase

Sumi‐Ichinose, C., Hasegawa, S., Ichinose, H., Sawada, H., Kobayashi, K., Sakai, M., Fujii, T., Nomura, H., Nomura, T., Nagatsu, I., Hagino, Y., Fujita, K. & Nagatsu, T., 01-01-1995, : : Journal of Neurochemistry. 64, 2, p. 514-524 11 p.

研究成果: Article

29 引用 (Scopus)

Isolation of a full-length cDNA clone for human GTP cyclohydrolase I type 1 from pheochromocytoma

Nomura, T., Ohtsuki, M., Matsui, S., Sumi-Ichinose, C., Nomura, H., Hagino, Y., Iwase, K., Ichinose, H., Fujita, K. & Nagatsu, T., 01-02-1995, : : Journal of Neural Transmission. 101, 1-3, p. 237-242 6 p.

研究成果: Article

13 引用 (Scopus)

Metabolic Effects of Glibenclamide in Isolated Rat Hepatocytes in the Absence of Extracellular Ca2+

Nomura, T., Ohtsuki, M., Watanabe, T., Hasegawa, S., Matsui, S., Tomita, A., Sumi-Ichinose, C., Nomura, H. & Hagino, Y., 01-01-1995, : : The Japanese Journal of Pharmacology. 69, 2, p. 173-176 4 p.

研究成果: Article

1993

Cloning and sequencing of cDNA encoding mouse GTP cyclohydrolase 1

Nomura, T., Ichinose, H., Sumi-Ichinose, C., Nomura, H., Hagino, Y., Fujita, K. & Nagatsu, T., 15-03-1993, : : Biochemical and Biophysical Research Communications. 191, 2, p. 523-527 5 p.

研究成果: Article

47 引用 (Scopus)

α1B-Adrenoceptor-mediated stimulation of Ca2+ mobilization and cAMP accumulation in isolated rat hepatocytes

Nomura, T., Kondo, H., Hasegawa, S., Watanabe, T., Yokoyama, R., Ukai, K., Tachibana, M., Sumi-Ichinose, C., Nomura, H. & Hagino, Y., 15-07-1993, : : European Journal of Pharmacology: Molecular Pharmacology. 246, 2, p. 113-120 8 p.

研究成果: Article

11 引用 (Scopus)
1992
81 引用 (Scopus)

Tissue-Specific Alternative Splicing of the First Exon Generates Two Types of mRNAs in Human Aromatic L-Amino Acid Decarboxylase

Ichinose, H., Ohye, T., Fujita, K., Nagatsu, T., Sumi-Ichinose, C. & Hagino, Y., 01-02-1992, : : Biochemistry. 31, 46, p. 11546-11550 5 p.

研究成果: Article

49 引用 (Scopus)
1990

Characterization of Recombinant Human Aromatic l‐Amino Acid Decarboxylase Expressed in COS Cells

Sumi, C., Ichinose, H. & Nagatsu, T., 09-1990, : : Journal of neurochemistry. 55, 3, p. 1075-1078 4 p.

研究成果: Article

35 引用 (Scopus)
1986

The presence of catechol-o-methyltransferase activity in separately cultured cerebromicrovascular endothelial and smooth muscle cells

Spatz, M., Kaneda, N., Sumi, C., Nagatsu, I., Creveling, C. R. & Nagatsu, T., 03-09-1986, : : Brain Research. 381, 2, p. 363-367 5 p.

研究成果: Article

20 引用 (Scopus)