Chiho Sumi-Ichinose

2022

Perturbation of monoamine metabolism and enhanced fear responses in mice defective in the regeneration of tetrahydrobiopterin

Miyajima, K., Sudo, Y., Sanechika, S., Hara, Y., Horiguchi, M., Xu, F., Suzuki, M., Hara, S., Tanda, K., Inoue, K. I., Takada, M., Yoshioka, N., Takebayashi, H., Mori-Kojima, M., Sugimoto, M., Sumi-Ichinose, C., Kondo, K., Takao, K., Miyakawa, T. & Ichinose, H., 04-2022, In: Journal of neurochemistry. 161, 2, p. 129-145 17 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

1 被引用数 (Scopus)

Priapism caused by partial deficiency of tetrahydrobiopterin through hypofunction of the sympathetic neurons in sepiapterin reductase gene-disrupted mice

Sumi-Ichinose, C., Suganuma, Y., Kano, T., Ikemoto, K., Ihira, N., Ichinose, H. & Kondo, K., 05-2022, In: Journal of Inherited Metabolic Disease. 45, 3, p. 621-634 14 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

1 被引用数 (Scopus)

Quinonoid dihydropteridine reductase, a tetrahydrobiopterin-recycling enzyme, contributes to 5-hydroxytryptamine-associated platelet aggregation in mice

Suganuma, Y., Sumi-Ichinose, C., Kano, T., Ikemoto, K., Matsui, T., Ichinose, H. & Kondo, K., 11-2022, In: Journal of Pharmacological Sciences. 150, 3, p. 173-179 7 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

2021

Salivary neopterin and related pterins: Their comparison to those in plasma and changes in individuals

Ikemoto, K., Sumi-Ichinose, C., Suganuma, Y., Kano, T., Ihira, N., Nagatsu, T. & Kondo, K., 01-10-2021, In: Journal of Biochemistry. 170, 4, p. 559-567 9 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

2 被引用数 (Scopus)

Tyrosine hydroxylase conditional KO mice reveal peripheral tissue-dependent differences in dopamine biosynthetic pathways

Miyajima, K., Kawamoto, C., Hara, S., Mori-Kojima, M., Ohye, T., Sumi-Ichinose, C., Saito, N., asaoka, T., Metzger, D. & Ichinose, H., 01-01-2021, In: Journal of Biological Chemistry. 296, 100544.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

5 被引用数 (Scopus)

2017

Sepiapterin reductase gene-disrupted mice suffer from hypertension with fluctuation and bradycardia

Sumi-Ichinose, C., Suganuma, Y., Kano, T., Ihira, N., Nomura, H., Ikemoto, K., Hata, T., Katoh, S., Ichinose, H. & Kondo, K., 01-03-2017, In: Physiological Reports. 5, 6, e13196.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

13 被引用数 (Scopus)

2014

Disturbed biopterin and folate metabolism in the Qdpr-deficient mouse

Xu, F., Sudo, Y., Sanechika, S., Yamashita, J., Shimaguchi, S., Honda, S. I., Sumi-Ichinose, C., Mori-Kojima, M., Nakata, R., Furuta, T., Sakurai, M., Sugimoto, M., Soga, T., Kondo, K. & Ichinose, H., 03-11-2014, In: FEBS Letters. 588, 21, p. 3924-3931 8 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

29 被引用数 (Scopus)

Targeted deletion of the C-terminus of the mouse adenomatous polyposis coli tumor suppressor results in neurologic phenotypes related to schizophrenia

Onouchi, T., Kobayashi, K., Sakai, K., Shimomura, A., Smits, R., Sumi-Ichinose, C., Kurosumi, M., Takao, K., Nomura, R., Iizuka-Kogo, A., Suzuki, H., Kondo, K., Akiyama, T., Miyakawa, T., Fodde, R. & Senda, T., 29-03-2014, In: Molecular brain. 7, 1, 21.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

26 被引用数 (Scopus)

2012

Recovery of neurogenic amines in phenylketonuria mice after liver-targeted gene therapy

Yagi, H., Sanechika, S., Ichinose, H., Sumi-Ichinose, C., Mizukami, H., Urabe, M., Ozawa, K. & Kume, A., 04-01-2012, In: Neuroreport. 23, 1, p. 30-34 5 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

8 被引用数 (Scopus)

2011

Cilostazol inhibits cytokine-induced tetrahydrobiopterin biosynthesis in human umbilical vein endothelial cells.

Shiraishi, H., Ikemoto, K., Tada, S., Udagawa, Y., Ohtsuki, M., Sumi-Ichinose, C., Kondo, K. & Nomura, T., 27-04-2011, In: Journal of atherosclerosis and thrombosis. 18, 4, p. 312-317 6 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

5 被引用数 (Scopus)

Compensatory regulation of dopamine after ablation of the tyrosine hydroxylase gene in the nigrostriatal projection

Tokuoka, H., Muramatsu, S. I., Sumi-Ichinose, C., Sakane, H., Kojima, M., Aso, Y., Nomura, T., Metzger, D. & Ichinose, H., 16-12-2011, In: Journal of Biological Chemistry. 286, 50, p. 43549-43558 10 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

24 被引用数 (Scopus)

Partial biopterin deficiency disturbs postnatal development of the dopaminergic system in the brain

Homma, D., Sumi-Ichinose, C., Tokuoka, H., Ikemoto, K., Nomura, T., Kondo, K., Katoh, S. & Ichinose, H., 14-01-2011, In: Journal of Biological Chemistry. 286, 2, p. 1445-1452 8 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

25 被引用数 (Scopus)

2010

Advanced research on dopamine signaling to develop drugs for the treatment of mental disorders: Regulation of dopaminergic neural transmission by tyrosine hydroxylase protein at nerve terminals

Sumi-Ichinose, C., Ichinose, H., Ikemoto, K., Nomura, T. & Kondo, K., 2010, In: Journal of Pharmacological Sciences. 114, 1, p. 17-24 8 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

10 被引用数 (Scopus)

2009

Nurr1 is required for maintenance of maturing and adult midbrain dopamine neurons

Kadkhodaei, B., Ito, T., Joodmardi, E., Mattsson, B., Rouillard, C., Carta, M., Muramatsu, S. I., Sumi-Ichinose, C., Nomura, T., Metzger, D., Chambon, P., Lindqvist, E., Larsson, N. G., Olson, L., Björklund, A., Ichinose, H. & Perlmann, T., 16-12-2009, In: Journal of Neuroscience. 29, 50, p. 15923-15932 10 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

274 被引用数 (Scopus)

2008

2,4-Diamino-6-hydroxypyrimidine (DAHP) suppresses cytokine-induced VCAM-1 expression on the cell surface of human umbilical vein endothelial cells in a BH₄-independent manner

Ikemoto, K., Matsumoto, T., Ohtsuki, M., Itoh, M., Tada, S., Udagawa, Y., Sumi-Ichinose, C., Kondo, K. & Nomura, T., 07-2008, In: Biochimica et Biophysica Acta - General Subjects. 1780, 7-8, p. 960-965 6 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

7 被引用数 (Scopus)

A brain-specific decrease of the tyrosine hydroxylase protein in sepiapterin reductase-null mice-as a mouse model for Parkinson's disease

Takazawa, C., Fujimoto, K., Homma, D., Sumi-Ichinose, C., Nomura, T., Ichinose, H. & Katoh, S., 21-03-2008, In: Biochemical and Biophysical Research Communications. 367, 4, p. 787-792 6 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

34 被引用数 (Scopus)

Differential involvement of striosome and matrix dopamine systems in a transgenic model of dopa-responsive dystonia

Sato, K., Sumi-Ichinose, C., Kaji, R., Ikemoto, K., Nomura, T., Nagatsu, I., Ichinose, H., Ito, M., Sako, W., Nagahiro, S., Graybiel, A. M. & Goto, S., 26-08-2008, In: Proceedings of the National Academy of Sciences of the United States of America. 105, 34, p. 12551-12556 6 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

81 被引用数 (Scopus)

Increased expression of tyrosine hydroxylase and anomalous neurites in catecholaminergic neurons of ATF-2 null mice

Kojima, M., Suzuki, T., Maekawa, T., Ishii, S., Sumi-Ichinose, C., Nomura, T. & Ichinose, H., 15-02-2008, In: Journal of Neuroscience Research. 86, 3, p. 544-552 9 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

4 被引用数 (Scopus)

Metabolism of tetrahydrobiopterin: Its relevance in monoaminergic neurons and neurological disorders

Ichinose, H., Nomura, T. & Sumi-Ichinose, C., 2008, In: Chemical Record. 8, 6, p. 378-385 8 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

20 被引用数 (Scopus)

2005

Genetically rescued tetrahydrobiopterin-depleted mice survive with hyperphenylalaninemia and region-specific monoaminergic abnormalities

Sumi-Ichinose, C., Urano, F., Shimomura, A., Sato, T., Ikemoto, K., Shiraishi, H., Senda, T., Ichinose, H. & Nomura, T., 2005, In: Journal of neurochemistry. 95, 3, p. 703-714 12 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

22 被引用数 (Scopus)

2003

cGMP inhibits GTP cyclohydrolase I activity and biosynthesis of tetrahydrobiopterin in human umbilical vein endothelial cells

Shiraishi, H., Kato, T., Atsuta, K., Sumi-Ichinose, C., Ohtsuki, M., Itoh, M., Hishida, H., Tada, S., Udagawa, Y., Nagatsu, T., Hagino, Y., Ichinose, H. & Nomura, T., 11-2003, In: Journal of Pharmacological Sciences. 93, 3, p. 265-271 7 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

8 被引用数 (Scopus)

2002

cAMP inhibits cytokine-induced biosynthesis of tetrahydrobiopterin in human umbilical vein endothelial cells

Ohtsuki, M., Shiraishi, H., Kato, T., Kuroda, R., Tazawa, M., Sumi-Ichinose, C., Tada, S., Udagawa, Y., Itoh, M., Hishida, H., Ichinose, H., Nagatsu, T., Hagino, Y. & Nomura, T., 22-03-2002, In: Life Sciences. 70, 18, p. 2187-2198 12 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

8 被引用数 (Scopus)

Regulations and pathophysiological significance of the biosynthesis of tetrahydrobiopterin in human endothelial cells

Shiraishi, H., Ohtsuki, M., Sumi-Ichinose, C. & Nomura, T., 2002, In: Folia Pharmacologica Japonica. 120, SUPPL. 1, p. 73P-75P

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

2001

Catecholamines and serotonin are differently regulated by tetrahydrobiopterin. A study from 6-pyruvoyltetrahydropterin synthase knockout mice

Sumi-Ichinose, C., Urano, F., Kuroda, R., Ohye, T., Kojima, M., Tazawa, M., Shiraishi, H., Hagino, Y., Nagatsu, T., Nomura, T. & Ichinose, H., 02-11-2001, In: Journal of Biological Chemistry. 276, 44, p. 41150-41160 11 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

124 被引用数 (Scopus)

2000

Effects of sulfhydryl reagents on nitric oxide release from a nitric oxide donor NOR 3 in the presence of rat hepatocytes

Nomura, H., Tazawa, M., Kuroda, R., Shiraishi, H., Sumi-Ichinose, C., Matsui, S., Ohtsuki, M., Hagino, Y. & Nomura, T., 11-2000, In: Pharmacology and Toxicology. 87, 5, p. 246-248 3 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

GTP cyclohydrolase I from Tetrahymena pyriformis: Cloning of cDNA and expression

Tazawa, M., Ohtsuki, M., Sumi-Ichinose, C., Shiraishi, H., Kuroda, R., Hagino, Y., Nakashima, S., Nozawa, Y., Ichinose, H., Nagatsu, T. & Nomura, T., 01-09-2000, In: Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology. 127, 1, p. 65-73 9 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

6 被引用数 (Scopus)

1999

Molecular cloning of the human Nurr1 gene: Characterization of the human gene and cDNAs

Ichinose, H., Ohye, T., Suzuki, T., Sumi-Ichinose, C., Nomura, T., Hagino, Y. & Nagatsu, T., 16-04-1999, In: Gene. 230, 2, p. 233-239 7 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

50 被引用数 (Scopus)

1998

Enzymes related to catecholamine biosynthesis in Tetrahymena pyriformis. Presence of GTP cyclohydrolase I

Nomura, T., Tazawa, M., Ohtsuki, M., Sumi-Ichinose, C., Hagino, Y., Ota, A., Nakashima, A., Mori, K., Sugimoto, T., Ueno, O., Nozawa, Y., Ichinose, H. & Nagatsu, T., 1998, In: Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology. 120, 4, p. 753-760 8 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

10 被引用数 (Scopus)

Nitric oxide donor NOR 3 inhibits ketogenesis from oleate in isolated rat hepatocytes by a cyclic GMP-independent mechanism

Nomura, T., Ohtsuki, M., Matsui, S., Sumi-Ichinose, C., Nomura, H. & Hagino, Y., 1998, In: Pharmacology and Toxicology. 82, 1, p. 40-46 7 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

7 被引用数 (Scopus)

1997

SNF2β-BRG1 is essential for the viability of F9 murine embryonal carcinoma cells

Sumi-Ichinose, C., Ichinose, H., Metzger, D. & Chambon, P., 10-1997, In: Molecular and Cellular Biology. 17, 10, p. 5976-5986 11 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

143 被引用数 (Scopus)

1996

Analysis of an alternative promoter that regulates tissue-specific expression of the human aromatic L-amino acid decarboxylase gene in cultured cell lines

Sumi-Ichinose, C., Hasegawa, S., Ohtsuki, M., Nomura, H., Nomura, T., Hagino, Y., Fujita, K. & Nagatsu, T., 1996, In: Journal of Neural Transmission. 103, 1-2, p. 1-15 15 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

3 被引用数 (Scopus)

1995

Analysis of the alternative promoters that regulate tissue-specific expression of human aromatic L-amino acid decarboxylase

Sumi-Ichinose, C., Hasegawa, S., Ichinose, H., Sawada, H., Kobayashi, K., Sakai, M., Fujii, T., Nomura, H., Nomura, T., Nagatsu, I., Hagino, Y., Fujita, K. & Nagatsu, T., 02-1995, In: Journal of neurochemistry. 64, 2, p. 514-524 11 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

35 被引用数 (Scopus)

Isolation of a full-length cDNA clone for human GTP cyclohydrolase I type 1 from pheochromocytoma

Nomura, T., Ohtsuki, M., Matsui, S., Sumi-Ichinose, C., Nomura, H., Hagino, Y., Iwase, K., Ichinose, H., Fujita, K. & Nagatsu, T., 02-1995, In: Journal of Neural Transmission. 101, 1-3, p. 237-242 6 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

13 被引用数 (Scopus)

Metabolic Effects of Glibenclamide in Isolated Rat Hepatocytes in the Absence of Extracellular Ca²⁺

Nomura, T., Ohtsuki, M., Watanabe, T., Hasegawa, S., Matsui, S., Tomita, A., Sumi-Ichinose, C., Nomura, H. & Hagino, Y., 1995, In: The Japanese Journal of Pharmacology. 69, 2, p. 173-176 4 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

1993

Cloning and sequencing of cDNA encoding mouse GTP cyclohydrolase 1

Nomura, T., Ichinose, H., Sumi-Ichinose, C., Nomura, H., Hagino, Y., Fujita, K. & Nagatsu, T., 15-03-1993, In: Biochemical and Biophysical Research Communications. 191, 2, p. 523-527 5 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

49 被引用数 (Scopus)

α_1B-Adrenoceptor-mediated stimulation of Ca²⁺ mobilization and cAMP accumulation in isolated rat hepatocytes

Nomura, T., Kondo, H., Hasegawa, S., Watanabe, T., Yokoyama, R., Ukai, K., Tachibana, M., Sumi-Ichinose, C., Nomura, H. & Hagino, Y., 15-07-1993, In: European Journal of Pharmacology: Molecular Pharmacology. 246, 2, p. 113-120 8 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

11 被引用数 (Scopus)

1992

Molecular Cloning of Genomic DNA and Chromosomal Assignment of the Gene for Human Aromatic L-Amino Acid Decarboxylase, the Enzyme for Catecholamine and Serotonin Biosynthesis

Sumi-Ichinose, C., Ichinose, H., Nagatsu, T., Takahashi, E. I. & Hon, T. A., 01-02-1992, In: Biochemistry. 31, 8, p. 2229-2238 10 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

94 被引用数 (Scopus)

Tissue-Specific Alternative Splicing of the First Exon Generates Two Types of mRNAs in Human Aromatic L-Amino Acid Decarboxylase

Ichinose, H., Ohye, T., Fujita, K., Nagatsu, T., Sumi-Ichinose, C. & Hagino, Y., 01-02-1992, In: Biochemistry. 31, 46, p. 11546-11550 5 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

60 被引用数 (Scopus)

1990

Characterization of Recombinant Human Aromatic l‐Amino Acid Decarboxylase Expressed in COS Cells

Sumi, C., Ichinose, H. & Nagatsu, T., 09-1990, In: Journal of neurochemistry. 55, 3, p. 1075-1078 4 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

39 被引用数 (Scopus)

1986

The presence of catechol-o-methyltransferase activity in separately cultured cerebromicrovascular endothelial and smooth muscle cells

Spatz, M., Kaneda, N., Sumi, C., Nagatsu, I., Creveling, C. R. & Nagatsu, T., 03-09-1986, In: Brain Research. 381, 2, p. 363-367 5 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

20 被引用数 (Scopus)

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