• 2814 引用
  • 30 h指数
1992 …2020

Research output per year

Pureに変更を加えた場合、すぐここに表示されます。

研究成果

  • 2814 引用
  • 30 h指数
  • 62 Article
  • 2 Comment/debate
  • 2 Letter
  • 1 Review article
フィルター
Article

A cyclooxygenase-2 inhibitor attenuates white matter damage in chronic cerebral ischemia

Wakita, H., Tomimoto, H., Akiguchi, I., Lin, J. X., Miyamoto, K. & Oka, N., 14-05-1999, : : Neuroreport. 10, 7, p. 1461-1465 5 p.

研究成果: Article

44 引用 (Scopus)

Alterations in glia and axons in the brains of Binswanger's disease patients

Akiguchi, I., Tomimoto, H., Suenaga, T., Wakita, H. & Budka, H., 07-1997, : : Stroke. 28, 7, p. 1423-1429 7 p.

研究成果: Article

105 引用 (Scopus)

Alterations of the blood-brain barrier and glial cells in white-matter lesions in cerebrovascular and Alzheimer's disease patients

Tomimoto, H., Akiguchi, I., Suenaga, T., Nishimura, M., Wakita, H., Nakamura, S. & Kimura, J., 11-1996, : : Stroke. 27, 11, p. 2069-2074 6 p.

研究成果: Article

142 引用 (Scopus)

A novel stem cell source for vasculogenesis in ischemia: Subfraction of side population cells from dental pulp

Iohara, K., Zheng, L., Wake, H., Ito, M., Nabekura, J., Wakita, H., Nakamura, H., Into, T., Matsushita, K. & Nakashima, M., 01-09-2008, : : Stem Cells. 26, 9, p. 2408-2418 11 p.

研究成果: Article

168 引用 (Scopus)

Astroglial expression of ATL-derived factor, a human thioredoxin homologue, in the gerbil brain after transient global ischemia

Tomimoto, H., Akiguchi, I., Wakita, H., Kimura, J., Hori, K. & Yodoi, J., 15-10-1993, : : Brain Research. 625, 1, p. 1-8 8 p.

研究成果: Article

47 引用 (Scopus)

Axonal damage and demyelination in the white matter after chronic cerebral hypoperfusion in the rat

Wakita, H., Tomimoto, H., Akiguchi, I., Matsuo, A., Lin, J. X., Ihara, M. & McGeer, P. L., 04-01-2002, : : Brain Research. 924, 1, p. 63-70 8 p.

研究成果: Article

141 引用 (Scopus)

Blood-brain barrier disruption in white matter lesions in a rat model of chronic cerebral hypoperfusion

Ueno, M., Tomimoto, H., Akiguchi, I., Wakita, H. & Sakamoto, H., 01-01-2002, : : Journal of Cerebral Blood Flow and Metabolism. 22, 1, p. 97-104 8 p.

研究成果: Article

98 引用 (Scopus)

Blood-brain barrier dysfunction in Binswanger's disease; An immunohistochemical study

Akiguchi, I., Tomimoto, H., Suenaga, T., Wakita, H. & Budka, H., 12-1997, : : Acta Neuropathologica. 95, 1, p. 78-84 7 p.

研究成果: Article

82 引用 (Scopus)

Caudoputamen is damaged by hypocapnia during mechanical ventilation in a rat model of chronic cerebral hypoperfusion

Miyamoto, E., Tomimoto, H., Nakao, S. I., Wakita, H., Akiguchi, I., Miyamoto, K. & Shingu, K., 01-01-2001, : : Stroke. 32, 12, p. 2920-2925 6 p.

研究成果: Article

20 引用 (Scopus)

Changes in glial cells in Binswanger-type infarction

Tomimoto, H., Akiguchi, I., Wakita, H. & Kimura, J., 01-01-1994, : : Brain and Nerve. 46, 8, p. 771-779 9 p.

研究成果: Article

3 引用 (Scopus)

Chronic cerebral hypoperfusion activates AIM2 and NLRP3 inflammasome

Matsuyama, H., Shindo, A., Shimada, T., Yata, K., Wakita, H., Takahashi, R. & Tomimoto, H., 01-06-2020, : : Brain Research. 1736, 146779.

研究成果: Article

Chronic cerebral hypoperfusion induced by right unilateral common carotid artery occlusion causes delayed white matter lesions and cognitive impairment in adult mice

Yoshizaki, K., Adachi, K., Kataoka, S., Watanabe, A., Tabira, T., Takahashi, K. & Wakita, H., 01-04-2008, : : Experimental Neurology. 210, 2, p. 585-591 7 p.

研究成果: Article

104 引用 (Scopus)

Chronic cerebral hypoperfusion induces MMP-2 but not MMP-9 expression in the microglia and vascular endothelium of white matter

Ihara, M., Tomimoto, H., Kinoshita, M., Oh, J., Noda, M., Wakita, H., Akiguchi, I. & Shibasaki, H., 01-01-2001, : : Journal of Cerebral Blood Flow and Metabolism. 21, 7, p. 828-834 7 p.

研究成果: Article

80 引用 (Scopus)

Chronic cerebral hypoperfusion induces white matter lesions and loss of oligodendroglia with DNA fragmentation in the rat

Tomimoto, H., Ihara, M., Wakita, H., Ohtani, R., Lin, J. X., Akiguchi, I., Kinoshita, M. & Shibasaki, H., 01-12-2003, : : Acta Neuropathologica. 106, 6, p. 527-534 8 p.

研究成果: Article

120 引用 (Scopus)

Chronic cerebral hypoperfusion upregulates leptin receptor expression in astrocytes and tau phosphorylation in tau transgenic mice

Shimada, T., Shindo, A., Matsuyama, H., Yata, K., Niwa, A., Sasaki, R., Ayaki, T., Maki, T., Wakita, H. & Tomimoto, H., 21-06-2019, : : Neuroscience Letters. 704, p. 133-140 8 p.

研究成果: Article

1 引用 (Scopus)

Coagulation activation in patients with Binswanger disease

Tomimoto, H., Akiguchi, I., Wakita, H., Osaki, A., Hayashi, M. & Yamamoto, Y., 01-09-1999, : : Archives of Neurology. 56, 9, p. 1104-1108 5 p.

研究成果: Article

40 引用 (Scopus)
13 引用 (Scopus)

Cyclooxygenase-2 is induced in microglia during chronic cerebral ischemia in humans

Tomimoto, H., Akiguchi, I., Wakita, H., Lin, J. X. & Budka, H., 01-2000, : : Acta Neuropathologica. 99, 1, p. 26-30 5 p.

研究成果: Article

82 引用 (Scopus)

Cytopathological alterations and therapeutic approaches in Binswanger's disease

Akiguchi, I., Tomimoto, H., Wakita, H., Yamamoto, Y., Suenaga, T., Ueno, M. & Budka, H., 08-03-1999, : : Neuropathology. 19, 1, p. 119-128 10 p.

研究成果: Article

5 引用 (Scopus)

Dental pulp-derived CD31-/CD146- side population stem/progenitor cells enhance recovery of focal cerebral ischemia in rats

Sugiyama, M., Iohara, K., Wakita, H., Hattori, H., Ueda, M., Matsushita, K. & Nakashima, M., 01-05-2011, : : Tissue Engineering - Part A. 17, 9-10, p. 1303-1311 9 p.

研究成果: Article

62 引用 (Scopus)

Distribution of ischemic leukoaraiosis in MRI: A difference from white matter lesions in CADASIL

Tomimoto, H., Ohtani, R., Wakita, H., Lin, J. X., Miki, Y. & Mizuno, T., 01-02-2005, : : Brain and Nerve. 57, 2, p. 125-130 6 p.

研究成果: Article

5 引用 (Scopus)

Distribution of NADPH-diaphorase in the cerebral blood vessels of rats: a histochemical study

Tomimoto, H., Akiguchi, I., Wakita, H., Nakamura, S. & Kimura, J., 25-06-1993, : : Neuroscience Letters. 156, 1-2, p. 105-108 4 p.

研究成果: Article

23 引用 (Scopus)

Distribution of nitric oxide synthase in the human cerebral blood vessels and brain tissues

Tomimoto, H., Nishimura, M., Suenaga, T., Nakamura, S., Akiguchi, I., Wakita, H., Kimura, J. & Mayer, B., 11-1994, : : Journal of Cerebral Blood Flow and Metabolism. 14, 6, p. 930-938 9 p.

研究成果: Article

55 引用 (Scopus)

Dose-dependent, protective effect of FK506 against white matter changes in the rat brain after chronic cerebral ischemia

Wakita, H., Tomimoto, H., Akiguchi, I. & Kimura, J., 04-05-1998, : : Brain Research. 792, 1, p. 105-113 9 p.

研究成果: Article

88 引用 (Scopus)

Effects of an antithrombin drug in patients with subacute exacerbations of Binswanger disease

Tomimoto, H., Akiguchi, I., Ohtani, R., Yagi, H., Ogura, S. & Wakita, H., 11-2000, : : Internal Medicine. 39, 11, p. 966-969 4 p.

研究成果: Article

5 引用 (Scopus)

Effects of antithrombin on Binswanger's disease with antiphospholipid antibody syndrome

Akiguchi, I., Tomimoto, H., Kinoshita, M., Wakita, H., Osaki, A., Nishimura, M. & Kimura, J., 15-01-1999, : : Neurology. 52, 2, p. 398-401 4 p.

研究成果: Article

13 引用 (Scopus)

Effects of exercise and bryostatin-1 on serotonin dynamics after cerebral infarction

Mizutani, K., Sonoda, S., Wakita, H., Okazaki, H., Katoh, Y., Chihara, T. & Shimpo, K., 15-06-2016, : : NeuroReport. 27, 9, p. 659-664 6 p.

研究成果: Article

5 引用 (Scopus)

Effects of perindopril-based blood pressure lowering and of patient characteristics on the progression of silent brain infarct: The perindopril protection against recurrent stroke study (PROGRESS) CT substudy in Japan

Hasegawa, Y., Yamaguchi, T., Omae, T., Woodward, M., Chalmers, J., Takasaki, M., Iwamoto, T., Tohgi, H., Takahashi, H., Konno, S., Uchiyama, S., Kimura, Y., Hayakawa, I., Miyamori, T., Ishitsuka, T., Shiokawa, O., Nakano, M., Takenoyama, T., Fukiyama, K., Muratani, H. および47人, Hirose, G., Kataoka, S., Sakai, F., Kanda, T., Kitagawa, Y., Yoshitoshi, M., Shinohara, Y., Takizawa, S., Kazabari, S., Mihara, B., Kawagishi, Y., Makishita, H., Isomura, K., Tabata, K., Nakagawa, S., Okada, H., Takeda, A., Nakajima, K., Makino, M., Hirata, Y., Watahiki, Y., Kawamura, J., Yoshikawa, N., Takastuka, K., Akiguchi, I., Wakita, H., Tomimoto, H., Nakamura, S., Kohriyama, T., Hiwada, K., Shigematsu, Y., Yanagihara, T., Matsumoto, M., Ueda, H., Nishimaru, K., Setsu, K., Kobayashi, S., Yamaguchi, S., Hashimoto, S., Nakamura, M., Mitake, S., Uchida, M., Ishihara, N., Imai, N., Imaizumi, M., Hokezu, Y. & Satake, M., 01-03-2004, : : Hypertension Research. 27, 3, p. 147-156 10 p.

研究成果: Article

22 引用 (Scopus)

Encephalitogenic peptide (EP) in human cerebrovascular white matter lesions

Tomimoto, H., Akiguchi, I., Matsuo, A., Terai, K., Wakita, H., Kimura, J., McGeer, P. L. & Budka, H., 01-01-1997, : : Neuroreport. 8, 17, p. 3727-3730 4 p.

研究成果: Article

5 引用 (Scopus)

E-selectin targeting to visualize tumors in vivo

Hirai, M., Hiramatsu, Y., Iwashita, S., Otani, T., Chen, L., Li, Y. G., Okada, M., Oie, K., Igarashi, K., Wakita, H. & Seno, M., 01-03-2010, : : Contrast Media and Molecular Imaging. 5, 2, p. 70-77 8 p.

研究成果: Article

10 引用 (Scopus)

Expression of S100 protein and protective effect of arundic acid on the rat brain in chronic cerebral hypoperfusion

Ohtani, R., Tomimoto, H., Wakita, H., Kitaguchi, H., Nakaji, K. & Takahashi, R., 02-03-2007, : : Brain Research. 1135, 1, p. 195-200 6 p.

研究成果: Article

18 引用 (Scopus)
8 引用 (Scopus)
220 引用 (Scopus)

Glial expression of cytokines in the brains of cerebrovascular disease patients

Tomimoto, H., Akiguchi, I., Wakita, H., Kinoshita, A., Ikemoto, A., Nakamura, S. & Kimura, J., 01-09-1996, : : Acta Neuropathologica. 92, 3, p. 281-287 7 p.

研究成果: Article

71 引用 (Scopus)

Histochemical demonstration of membranous localization of endothelial nitric oxide synthase in endothelial cells of the rat brain

Tomimoto, H., Akiguchi, I., Wakita, H., Nakamura, S. & Kimura, J., 19-12-1994, : : Brain Research. 667, 1, p. 107-110 4 p.

研究成果: Article

22 引用 (Scopus)

Homocysteine, another risk factor for Alzheimer disease, impairs apolipoprotein E3 function

Minagawa, H., Watanabe, A., Akatsu, H., Adachi, K., Ohtsuka, C., Terayama, Y., Hosono, T., Takahashi, S., Wakita, H., Jung, C. G., Komano, H. & Michikawa, M., 03-12-2010, : : Journal of Biological Chemistry. 285, 49, p. 38382-38388 7 p.

研究成果: Article

29 引用 (Scopus)

Hypophosphorylation of ribosomal protein S6 is a molecular mechanism underlying ischemic tolerance induced by either hibernation or preconditioning

Miyake, S. I., Wakita, H., Bernstock, J. D., Castri, P., Ruetzler, C., Miyake, J., Lee, Y. J. & Hallenbeck, J. M., 01-12-2015, : : Journal of neurochemistry. 135, 5, p. 943-957 15 p.

研究成果: Article

9 引用 (Scopus)

Ibudilast, a phosphodiesterase inhibitor, protects against white matter damage under chronic cerebral hypoperfusion in the rat

Wakita, H., Tomimoto, H., Akiguchi, I., Lin, J. X., Ihara, M., Ohtani, R. & Shibata, M., 28-11-2003, : : Brain Research. 992, 1, p. 53-59 7 p.

研究成果: Article

59 引用 (Scopus)

Immunohistochemical study of apolipoprotein E in human cerebrovascular white matter lesions

Tomimoto, H., Akiguchi, I., Suenaga, T., Wakita, H., Nakamura, S., Kimura, J. & Budka, H., 01-12-1995, : : Acta Neuropathologica. 90, 6, p. 608-614 7 p.

研究成果: Article

11 引用 (Scopus)

Ketamine attenuates hypocapnia-induced neuronal damage in the caudoputamen in a rat model of chronic cerebral hypoperfusion

Miyamoto, E., Nakao, S., Tomimoto, H., Wakita, H., Yamada, M., Masuzawa, M., Takahira, K., Sakamoto, S. & Shingu, K., 02-01-2004, : : Neuroscience Letters. 354, 1, p. 26-29 4 p.

研究成果: Article

12 引用 (Scopus)

Mucosal tolerization to E-selectin protects against memory dysfunction and white matter damage in a vascular cognitive impairment model

Wakita, H., Ruetzler, C., Illoh, K. O., Chen, Y., Takanohashi, A., Spatz, M. & Hallenbeck, J. M., 01-02-2008, : : Journal of Cerebral Blood Flow and Metabolism. 28, 2, p. 341-353 13 p.

研究成果: Article

30 引用 (Scopus)
5 引用 (Scopus)

Protective effect of cyclosporin a on white matter changes in the rat brain after chronic cerebral hypoperfusion

Wakita, H., Tomimoto, H., Akiguchi, I. & Kimura, J., 08-1995, : : Stroke. 26, 8, p. 1415-1422 8 p.

研究成果: Article

89 引用 (Scopus)

Protective effect of nicardipine hydrochloride on the evolution of delayed neuronal death. An immunohistochemical study

Tomimoto, H., Wakita, H., Akiguchi, I. & Kimura, J., 01-01-1994, : : Brain and Nerve. 46, 3, p. 251-256 6 p.

研究成果: Article

1 引用 (Scopus)
9 引用 (Scopus)
142 引用 (Scopus)

Regional accumulation of amyloid β A4 protein precursor in the gerbil brain following transient cerebral ischemia

Wakita, H., Tomimoto, H., Akiguchi, I., Ohnishi, K., Nakamura, S. & Kimura, J., 09-11-1992, : : Neuroscience Letters. 146, 2, p. 135-138 4 p.

研究成果: Article

56 引用 (Scopus)

Regressive changes of astroglia in white matter lesions in cerebrovascular disease and Alzheimer's disease patients

Tomimoto, H., Akiguchi, I., Wakita, H., Suenaga, T., Nakamura, S. & Kimura, J., 01-08-1997, : : Acta Neuropathologica. 94, 2, p. 146-152 7 p.

研究成果: Article

79 引用 (Scopus)

Selective accumulation of adiponectin in the cerebral cortex under chronic cerebral hypoperfusion in the rat

Takahashi, Y., Wakita, H., Mizutani, K., Watanabe, A., Sonoda, S. & Tomimoto, H., 27-01-2020, : : Neuroreport. 31, 2, p. 148-155 8 p.

研究成果: Article