年別の研究成果
年別の研究成果
検索結果
-
2023
Antisense oligonucleotide induced pseudoexon skipping and restoration of functional protein for Fukuyama muscular dystrophy caused by a deep-intronic variant
Enkhjargal, S., Sugahara, K., Khaledian, B., Nagasaka, M., Inagaki, H., Kurahashi, H., Koshimizu, H., Toda, T. & Taniguchi-Ikeda, M., 15-04-2023, In: Human molecular genetics. 32, 8, p. 1301-1312 12 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
5 被引用数 (Scopus) -
2021
Brain-derived neurotrophic factor predominantly regulates the expression of synapse-related genes in the striatum: Insights from in vitro transcriptomics
Koshimizu, H., Matsuoka, H., Nakajima, Y., Kawai, A., Ono, J., Ohta, K. I., Miki, T., Sunagawa, M., Adachi, N. & Suzuki, S., 12-2021, In: Neuropsychopharmacology reports. 41, 4, p. 485-495 11 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access10 被引用数 (Scopus) -
2020
Vexin is upregulated in cerebral cortical neurons by brain-derived neurotrophic factor
Koshimizu, H., Suzuki, S., Kawai, A., Miura, R., Ohta, K. I., Miki, T., Adachi, N. & Matsuoka, H., 01-09-2020, In: Neuropsychopharmacology reports. 40, 3, p. 275-280 6 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access2 被引用数 (Scopus) -
2019
Comprehensive behavioral analysis and quantification of brain free amino acids of C57BL/6J congenic mice carrying the 1473G allele in tryptophan hydroxylase-2
Koshimizu, H., Hirata, N., Takao, K., Toyama, K., Ichinose, T., Furuya, S. & Miyakawa, T., 03-2019, In: Neuropsychopharmacology reports. 39, 1, p. 56-60 5 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access5 被引用数 (Scopus) -
Genome-wide association study identifies a novel locus associated with psychological distress in the Japanese population
Koshimizu, H., Nogawa, S., Asano, S., Ikeda, M., Iwata, N., Takahashi, S., Saito, K. & Miyakawa, T., 01-12-2019, In: Translational psychiatry. 9, 1, 52.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access5 被引用数 (Scopus) -
2018
Corticotropin-releasing hormone-binding protein is up-regulated by brain-derived neurotrophic factor and is secreted in an activity-dependent manner in rat cerebral cortical neurons
Adachi, N., Suzuki, S., Matsuoka, H., Fushimi, S., Ono, J., Ohta, K. I., Hirai, Y., Miki, T. & Koshimizu, H., 07-2018, In: Journal of neurochemistry. 146, 1, p. 99-110 12 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access9 被引用数 (Scopus) -
2017
Functional interaction between BDNF and mGluR II in vitro: BDNF down-regulated mGluR II gene expression and an mGluR II agonist enhanced BDNF-induced BDNF gene expression in rat cerebral cortical neurons
Suzuki, S., Koshimizu, H., Adachi, N., Matsuoka, H., Fushimi, S., Ono, J., Ohta, K. I. & Miki, T., 01-03-2017, In: Peptides. 89, p. 42-49 8 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
16 被引用数 (Scopus) -
Transcriptomic immaturity of the hippocampus and prefrontal cortex in patients with alcoholism
Murano, T., Koshimizu, H., Hagihara, H. & Miyakawa, T., 15-03-2017, In: Scientific reports. 7, 44531.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access17 被引用数 (Scopus) -
2014
Comprehensive behavioral analysis of cluster of differentiation 47 knockout mice
Koshimizu, H., Takao, K., Matozaki, T., Ohnishi, H. & Miyakawa, T., 24-02-2014, In: PloS one. 9, 2, e89584.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access20 被引用数 (Scopus) -
2013
Deficiency of schnurri-2, an MHC enhancer binding protein, induces mild chronic inflammation in the brain and confers molecular, neuronal, and behavioral phenotypes related to schizophrenia
Takao, K., Kobayashi, K., Hagihara, H., Ohira, K., Shoji, H., Takai, S., Koshimizu, H., Umemori, J., Toyama, K., Nakamura, H. K., Kuroiwa, M., Maeda, J., Atsuzawa, K., Esaki, K., Yamaguchi, S., Furuya, S., Takagi, T., Walton, N. M., Hayashi, N. & Suzuki, H. & 7 others, , 07-2013, In: Neuropsychopharmacology. 38, 8, p. 1409-1425 17 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access138 被引用数 (Scopus) -
ENU-mutagenesis mice with a non-synonymous mutation in Grin1 exhibit abnormal anxiety-like behaviors, impaired fear memory, and decreased acoustic startle response
Umemori, J., Takao, K., Koshimizu, H., Takai, S., Furuse, T., Wakana, S. & Miyakawa, T., 2013, In: BMC Research Notes. 6, 1, 203.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access30 被引用数 (Scopus) -
2012
M 4muscarinic receptor knockout mice display abnormal social behavior and decreased prepulse inhibition
Koshimizu, H., Leiter, L. M. & Miyakawa, T., 2012, In: Molecular brain. 5, 1, 10.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access53 被引用数 (Scopus) -
Serpinins: Role in granule biogenesis, inhibition of cell death and cardiac function
Loh, Y. P., Koshimizu, H., Cawley, N. X. & Tota, B., 08-2012, In: Current Medicinal Chemistry. 19, 24, p. 4086-4092 7 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access9 被引用数 (Scopus) -
The novel chromogranin A-derived serpinin and pyroglutaminated serpinin peptides are positive cardiac β-adrenergic-like inotropes
Tota, B., Gentile, S., Pasqua, T., Bassino, E., Koshimizu, H., Cawley, N. X., Cerra, M. C., Loh, Y. P. & Angelone, T., 07-2012, In: FASEB Journal. 26, 7, p. 2888-2898 11 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access44 被引用数 (Scopus) -
2011
Adenomatous polyposis coli heterozygous knockout mice display hypoactivity and age-dependent working memory deficits
Koshimizu, H., Fukui, Y., Takao, K., Ohira, K., Tanda, K., Nakanishi, K., Toyama, K., Oshima, M., Taketo, M. M. & Miyakawa, T., 12-2011, In: Frontiers in Behavioral Neuroscience. DECEMBER研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access18 被引用数 (Scopus) -
BIT/SHPS-1 promotes antiapoptotic effect of BDNF on low potassium-induced cell death of cultured cerebellar granule neurons.
Koshimizu, H., Suzuki, S., Araki, T., Yamada, M., Kojima, M. & Hatanaka, H., 10-2011, In: Cellular and molecular neurobiology. 31, 7, p. 1027-1032 6 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
4 被引用数 (Scopus) -
Role of pGlu-serpinin, a novel chromogranin a-derived peptide in inhibition of cell death
Koshimizu, H., Cawley, N. X., Yergy, A. L. & Loh, Y. P., 10-2011, In: Journal of Molecular Neuroscience. 45, 2, p. 294-303 10 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access19 被引用数 (Scopus) -
Serpinin: A novel chromogranin a-derived, secreted peptide up-regulates protease nexin-1 expression and granule biogenesis in endocrine cells
Koshimizu, H., Cawley, N. X., Kim, T., Yergey, A. L. & Loh, Y. P., 05-2011, In: Molecular Endocrinology. 25, 5, p. 732-744 13 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access43 被引用数 (Scopus) -
2010
Carboxypeptidase E knockout mice exhibit abnormal dendritic arborization and spine morphology in central nervous system neurons
Woronowicz, A., Cawley, N. X., Chang, S. Y., Koshimizu, H., Phillips, A. W., Xiong, Z. G. & Loh, Y. P., 01-2010, In: Journal of Neuroscience Research. 88, 1, p. 64-72 9 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access28 被引用数 (Scopus) -
Chromogranin A: A new proposal for trafficking, processing and induction of granule biogenesis
Koshimizu, H., Kim, T., Cawley, N. X. & Loh, Y. P., 25-02-2010, In: Regulatory Peptides. 160, 1-3, p. 153-159 7 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access38 被引用数 (Scopus) -
Distinct signaling pathways of precursor BDNF and mature BDNF in cultured cerebellar granule neurons
Koshimizu, H., Hazama, S., Hara, T., Ogura, A. & Kojima, M., 04-2010, In: Neuroscience Letters. 473, 3, p. 229-232 4 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
62 被引用数 (Scopus) -
Reprint of: Chromogranin A: A new proposal for trafficking, processing and induction of granule biogenesis
Koshimizu, H., Kim, T., Cawley, N. X. & Loh, Y. P., 30-11-2010, In: Regulatory Peptides. 165, 1, p. 95-101 7 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access9 被引用数 (Scopus) -
2009
Biogenesis and transport of secretory granules to release site in neuroendocrine cells
Park, J. J., Koshimizu, H. & Loh, Y. P., 02-2009, In: Journal of Molecular Neuroscience. 37, 2, p. 151-159 9 p.研究成果: ジャーナルへの寄稿 › 総説 › 査読
25 被引用数 (Scopus) -
Multiple functions of precursor BDNF to CNS neurons: Negative regulation of neurite growth, spine formation and cell survival
Koshimizu, H., Kiyosue, K., Hara, T., Hazama, S., Suzuki, S., Uegaki, K., Nagappan, G., Zaitsev, E., Hirokawa, T., Tatsu, Y., Ogura, A., Lu, B. & Kojima, M., 2009, In: Molecular brain. 2, 1, 27.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access162 被引用数 (Scopus) -
Neuroprotective protein and carboxypeptidase E
Koshimizu, H., Senatorov, V., Loh, Y. P. & Gozes, I., 09-2009, In: Journal of Molecular Neuroscience. 39, 1-2, p. 1-8 8 p.研究成果: ジャーナルへの寄稿 › 総説 › 査読
18 被引用数 (Scopus) -
2008
Absence of carboxypeptidase E leads to adult hippocampal neuronal degeneration and memory deficits
Woronowicz, A., Koshimizu, H., Chang, S. Y., Cawley, N. X., Hill, J. M., Rodriguiz, R. M., Abebe, D., Dorfman, C., Senatorov, V., Zhou, A., Xiong, Z. G., Wetsel, W. C. & Loh, Y. P., 2008, In: Hippocampus. 18, 10, p. 1051-1063 13 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access55 被引用数 (Scopus) -
2007
Brain-derived neurotrophic factor regulates cholesterol metabolism for synapse development
Suzuki, S., Kiyosue, K., Hazama, S., Ogura, A., Kashihara, M., Hara, T., Koshimizu, H. & Kojima, M., 13-06-2007, In: Journal of Neuroscience. 27, 24, p. 6417-6427 11 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access140 被引用数 (Scopus) -
2005
Expression of cystatin C prevents oxidative stress-induced death in PC12 cells
Nishiyama, K., Konishi, A., Nishio, C., Araki-Yoshida, K., Hatanaka, H., Kojima, M., Ohmiya, Y., Yamada, M. & Koshimizu, H., 30-09-2005, In: Brain Research Bulletin. 67, 1-2, p. 94-99 6 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
38 被引用数 (Scopus) -
2004
BDNF-induced recruitment of TrkB receptor into neuronal lipid rafts: Roles in synaptic modulation
Suzuki, S., Numakawa, T., Shimazu, K., Koshimizu, H., Hara, T., Hatanaka, H., Mei, L., Lu, B. & Kojima, M., 20-12-2004, In: Journal of Cell Biology. 167, 6, p. 1205-1215 11 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access170 被引用数 (Scopus) -
Neuronal roles of the integrin-associated protein (IAP/ CD47) in developing cortical neurons
Numakawa, T., Ishimoto, T., Suzuki, S., Numakawa, Y., Adachi, N., Matsumoto, T., Yokomaku, D., Koshimizu, H., Fujimori, K. E., Hashimoto, R., Taguchi, T. & Kunugi, H., 08-10-2004, In: Journal of Biological Chemistry. 279, 41, p. 43245-43253 9 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access34 被引用数 (Scopus) -
2003
Apoptosis-signal regulating kinase-1 is involved in the low potassium-induced activation of p38 mitogen-activated protein kinase and c-Jun in cultured cerebellar granule neurons
Yamagishi, S., Yamada, M., Koshimizu, H., Takai, S., Hatanaka, H., Takeda, K., Ichijo, H., Shimoke, K. & Ikeuchi, T., 01-06-2003, In: Journal of Biochemistry. 133, 6, p. 719-724 6 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
17 被引用数 (Scopus) -
2002
Distinct usages of phospholipase Cγ and Shc in intracellular signaling stimulated by neurotrophins
Yamada, M., Numakawa, T., Koshimizu, H., Tanabe, K., Wada, K., Koizumi, S. & Hatanaka, H., 15-11-2002, In: Brain Research. 955, 1-2, p. 183-190 8 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
15 被引用数 (Scopus) -
Expression of CD47/integrin-associated protein induces death of cultured cerebral cortical neurons
Koshimizu, H., Araki, T., Takai, S., Yokomaku, D., Ishikawa, Y., Kubota, M., Sano, S. I., Hatanaka, H. & Yamada, M., 2002, In: Journal of neurochemistry. 82, 2, p. 249-257 9 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
24 被引用数 (Scopus) -
Shp-2 positively regulates brain-derived neurotrophic factor-promoted survival of cultured ventral mesencephalic dopaminergic neurons through a brain immunoglobulin-like molecule with tyrosine-based activation motifs/Shp substrate-1
Takai, S., Yamada, M., Araki, T., Koshimizu, H., Nawa, H. & Hatanaka, H., 2002, In: Journal of neurochemistry. 82, 2, p. 353-364 12 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
Open Access17 被引用数 (Scopus) -
2001
Roles of amino acid residues near the chromophore of photoactive yellow protein
Imamoto, Y., Koshimizu, H., Mihara, K., Hisatomi, O., Mizukami, T., Tsujimoto, K., Kataoka, M. & Tokunaga, F., 17-04-2001, In: Biochemistry. 40, 15, p. 4679-4685 7 p.研究成果: ジャーナルへの寄稿 › 学術論文 › 査読
53 被引用数 (Scopus)