• 8611 引用
  • 48 h指数
1985 …2020
Pureに変更を加えた場合、すぐここに表示されます。

研究成果 1985 2020

フィルター
Article
2020

Indoleamine-2,3-dioxygenase-1 is a molecular target for the protective activity of mood stabilizers against mania-like behavior induced by d-amphetamine

Tran, H. Q., Shin, E. J., Saito, K., Tran, T. V., Phan, D. H., Sharma, N., Kim, D. W., Choi, S. Y., Jeong, J. H., Jang, C. G., Cheong, J. H., Nabeshima, T. & Kim, H. C., 02-2020, : : Food and Chemical Toxicology. 136, 110986.

研究成果: Article

Indoleamine-Pyrrole 2,3,-Dioxygenase
amphetamine
Dextroamphetamine
emotions
Bipolar Disorder
1 引用 (Scopus)
Neural networks
Lung
Multiple Pulmonary Nodules
Biopsy
Tuning
2019
2 引用 (Scopus)

5-HT 1A receptor agonist 8-OH-DPAT induces serotonergic behaviors in mice via interaction between PKCδ and p47phox

Tran, H. Q., Shin, E. J., Hoai Nguyen, B. C., Phan, D. H., Kang, M. J., Jang, C. G., Jeong, J. H., Nah, S. Y., Mouri, A., Saito, K., Nabeshima, T. & Kim, H. C., 01-01-2019, : : Food and Chemical Toxicology. 123, p. 125-141 17 p.

研究成果: Article

8-Hydroxy-2-(di-n-propylamino)tetralin
Receptor, Serotonin, 5-HT1A
serotonin
agonists
Serotonin

A complementary scheme for automated detection of high-uptake regions on dedicated breast PET and whole-body PET/CT

Minoura, N., Teramoto, A., Ito, A., Yamamuro, O., Nishio, M., Saito, K. & Fujita, H., 01-09-2019, : : Radiological Physics and Technology. 12, 3, p. 260-267 8 p.

研究成果: Article

breast
Breast
tomography
Tomography
Axilla
2 引用 (Scopus)

Alteration of specific cytokine expression patterns in patients with breast cancer

Kawaguchi, K., Sakurai, M., Yamamoto, Y., Suzuki, E., Tsuda, M., Kataoka, T. R., Hirata, M., Nishie, M., Nojiri, T., Kumazoe, M., Saito, K. & Toi, M., 01-12-2019, : : Scientific reports. 9, 1, 2924.

研究成果: Article

公開
Breast Neoplasms
Cytokines
Healthy Volunteers
Interleukin-1
Interleukin-9
公開
Kynurenine
Knockout Mice
Biomarkers
Attention Deficit Disorder with Hyperactivity
Impulsive Behavior
machine learning
Mammography
breast
lesions
Breast
2 引用 (Scopus)

Automated classification of benign and malignant cells from lung cytological images using deep convolutional neural network

Teramoto, A., Yamada, A., Kiriyama, Y., Tsukamoto, T., Yan, K., Zhang, L., Imaizumi, K., Saito, K. & Fujita, H., 2019, : : Informatics in Medicine Unlocked. 16, 100205.

研究成果: Article

公開
Lung
Lenses
Cell Biology
Cause of Death
Lung Neoplasms
6 引用 (Scopus)
Tomography
Biopsy
Neural networks
Lung
Lung Neoplasms
Wave filters
chest
bones
Bone
Thorax

Changes in tryptophan metabolism during pregnancy and postpartum periods: Potential involvement in postpartum depressive symptoms

Teshigawara, T., Mouri, A., Kubo, H., Nakamura, Y., Shiino, T., Okada, T., Morikawa, M., Nabeshima, T., Ozaki, N., Yamamoto, Y. & Saito, K., 01-08-2019, : : Journal of Affective Disorders. 255, p. 168-176 9 p.

研究成果: Article

Tryptophan
Postpartum Period
Kynurenine
Depression
Pregnancy

Changes of liver fibrosis markers in patients with treatment by antiviral therapy

Ishidalr, H., Suetsugu, A., Furuta, N., Nohisa, Y., Takemura, M., Saito, K., Shirakam, Y. & Itou, H., 04-2019, : : Japanese Journal of Clinical Chemistry. 48, 2, p. 137-143 7 p.

研究成果: Article

Liver Cirrhosis
Liver
Antiviral Agents
Therapeutics
Serum
1 引用 (Scopus)
Nucleus Accumbens
Depression
Prefrontal Cortex
Hippocampus
Tyrosine 3-Monooxygenase
1 引用 (Scopus)
Glial Fibrillary Acidic Protein
Cerebrospinal Fluid
Biomarkers
Interleukin-27
Cytokines

Decline of plasma concentrations of interleukin-18 in severely malnourished patients with anorexia nervosa: Exploratory analysis

Tanaka, S., Oya-Ito, T., Murakami, Y., Saito, K., Furuta, S., Yu, Y., Imaeda, M., Kunimoto, S. & Ozaki, N., 03-2019, : : Nutrients. 11, 3, 540.

研究成果: Article

公開
interleukin-18
Interleukin-18
anorexia nervosa
Anorexia Nervosa
Malnutrition
2 引用 (Scopus)

Effect of antidepressant treatment on plasma levels of neuroinflammation-associated molecules in patients with somatic symptom disorder with predominant pain around the orofacial region

Miyauchi, T., Tokura, T., Kimura, H., Ito, M., Umemura, E., Sato (Boku), A., Nagashima, W., Tonoike, T., Yamamoto, Y., Saito, K., Kurita, K. & Ozaki, N., 01-07-2019, : : Human Psychopharmacology. 34, 4, e2698.

研究成果: Article

公開
Facial Pain
Burning Mouth Syndrome
Antidepressive Agents
Toothache
Macrophage Inflammatory Proteins
公開
Indoleamine-Pyrrole 2,3,-Dioxygenase
Lewis Lung Carcinoma
Tryptophan
Growth
Neoplasms
公開
kynurenine-oxoglutarate transaminase
Glycyrrhizic Acid
Kynurenic Acid
Kynurenine
Carbenoxolone
Kynurenine
Drug Discovery
Tryptophan
2018
10 引用 (Scopus)

Astroglial major histocompatibility complex class I following immune activation leads to behavioral and neuropathological changes

Sobue, A., Ito, N., Nagai, T., Shan, W., Hada, K., Nakajima, A., Murakami, Y., Mouri, A., Yamamoto, Y., Nabeshima, T., Saito, K. & Yamada, K., 01-05-2018, : : GLIA. 66, 5, p. 1034-1052 19 p.

研究成果: Article

Major Histocompatibility Complex
Astrocytes
Exosomes
Prefrontal Cortex
Poly I-C
7 引用 (Scopus)
Brain-Derived Neurotrophic Factor
Fructose
Epigenomics
Mothers
DNA Methylation
1 引用 (Scopus)

Higher levels of progranulin in cerebrospinal fluid of patients with lymphoma and carcinoma with CNS metastasis

Kimura, A., Takemura, M., Serrero, G., Yoshikura, N., Hayashi, Y., Saito, K. & Inuzuka, T., 01-05-2018, : : Journal of Neuro-Oncology. 137, 3, p. 455-462 8 p.

研究成果: Article

Cerebrospinal Fluid
Lymphoma
Central Nervous System
Neoplasm Metastasis
Carcinoma
7 引用 (Scopus)

IL-6 knockout mice are protected from cocaine-induced kindling behaviors; possible involvement of JAK2/STAT3 and PACAP signalings

Mai, H. N., Chung, Y. H., Shin, E. J., Sharma, N., Jeong, J. H., Jang, C. G., Saito, K., Nabeshima, T., Reglodi, D. & Kim, H. C., 01-06-2018, : : Food and Chemical Toxicology. 116, p. 249-263 15 p.

研究成果: Article

Pituitary Adenylate Cyclase-Activating Polypeptide
cocaine
Cocaine
Knockout Mice
interleukin-6
2 引用 (Scopus)
Indoleamine-Pyrrole 2,3,-Dioxygenase
STAT3 Transcription Factor
Lipopolysaccharides
Shock
Interleukin-6
7 引用 (Scopus)
Dextromethorphan
Receptor, Serotonin, 5-HT1A
Knockout Mice
Protein Kinase C
Up-Regulation
2017
5 引用 (Scopus)
Kynurenine 3-Monooxygenase
Myocarditis
Kynurenine
Encephalomyocarditis virus
Mortality
8 引用 (Scopus)

Association between increased serum GP88 (progranulin) concentrations and prognosis in patients with malignant lymphomas

Yamamoto, Y., Goto, N., Takemura, M., Yamasuge, W., Yabe, K., Takami, T., Miyazaki, T., Takeuchi, T., Shiraki, M., Shimizu, M., Adachi, S., Saito, K., Shibata, Y., Nakamura, N., Hara, T., Serrero, G., Saito, K. & Tsurumi, H., 10-2017, : : Clinica Chimica Acta. 473, p. 139-146 8 p.

研究成果: Article

Tumors
Lymphoma
Serum
Tissue
Proteins
4 引用 (Scopus)

Association between naturally occurring anti-amyloid β autoantibodies and medial temporal lobe atrophy in Alzheimer's disease

Kimura, A., Takemura, M., Saito, K., Yoshikura, N., Hayashi, Y. & Inuzuka, T., 01-02-2017, : : Journal of Neurology, Neurosurgery and Psychiatry. 88, 2, p. 126-131 6 p.

研究成果: Article

Temporal Lobe
Amyloid
Autoantibodies
Atrophy
Alzheimer Disease
4 引用 (Scopus)

Comparison of cerebrospinal fluid profiles in Alzheimer’s disease with multiple cerebral microbleeds and cerebral amyloid angiopathy-related inflammation

Kimura, A., Takemura, M., Saito, K., Yoshikura, N., Hayashi, Y., Harada, N., Nishida, H., Nakajima, H. & Inuzuka, T., 01-02-2017, : : Journal of Neurology. 264, 2, p. 373-381 9 p.

研究成果: Article

Cerebral Amyloid Angiopathy
Cerebrospinal Fluid
Alzheimer Disease
Inflammation
Magnetic Resonance Imaging
7 引用 (Scopus)

Effect of water-immersion restraint stress on tryptophan catabolism through the kynurenine pathway in rat tissues

Ohta, Y., Kubo, H., Yashiro, K., Ohashi, K., Tsuzuki, Y., Wada, N., Yamamoto, Y. & Saito, K., 01-05-2017, : : Journal of Physiological Sciences. 67, 3, p. 361-372 12 p.

研究成果: Article

Indoleamine-Pyrrole 2,3,-Dioxygenase
Kynurenine
Tryptophan Oxygenase
Immersion
Tryptophan
8 引用 (Scopus)

Increased cerebrospinal fluid progranulin correlates with interleukin-6 in the acute phase of neuromyelitis optica spectrum disorder

Kimura, A., Takemura, M., Saito, K., Serrero, G., Yoshikura, N., Hayashi, Y. & Inuzuka, T., 15-04-2017, : : Journal of Neuroimmunology. 305, p. 175-181 7 p.

研究成果: Article

Neuromyelitis Optica
Cerebrospinal Fluid
Interleukin-6
Multiple Sclerosis
Cerebrospinal Fluid Proteins
8 引用 (Scopus)
Kynurenine 3-Monooxygenase
Antidepressive Agents
Knockout Mice
Kynurenine
Tryptophan
3 引用 (Scopus)

Sake lees extract improves hepatic lipid accumulation in high fat diet-fed mice

Kubo, H., Hoshi, M., Matsumoto, T., Irie, M., Oura, S., Tsutsumi, H., Hata, Y., Yamamoto, Y. & Saito, K., 03-06-2017, : : Lipids in Health and Disease. 16, 1, 106.

研究成果: Article

High Fat Diet
Nutrition
Liver
Fats
Lipids

Serum concentrations of l-kynurenine predict clinical outcomes of patients with peripheral T-cell lymphoma, not otherwise specified

Shibata, Y., Hara, T., Matsumoto, T., Nakamura, N., Nakamura, H., Ninomiya, S., Kitagawa, J., Goto, N., Nannya, Y., Ito, H., Kito, Y., Miyazaki, T., Takeuchi, T., Saito, K., Seishima, M., Takami, T., Moriwaki, H., Shimizu, M. & Tsurumi, H., 12-2017, : : Hematological Oncology. 35, 4, p. 637-644 8 p.

研究成果: Article

Peripheral T-Cell Lymphoma
Kynurenine
Serum
Indoleamine-Pyrrole 2,3,-Dioxygenase
Essential Amino Acids
2016
Personal Health Records
Precision Medicine
Biomarkers
Medicine
Health
Medicine
Databases
Health
Personal Health Records
Reproductive Medicine
22 引用 (Scopus)

Depressive symptoms as a side effect of Interferon-α therapy induced by induction of indoleamine 2,3-dioxygenase 1

Murakami, Y., Ishibashi, T., Tomita, E., Imamura, Y., Tashiro, T., Watcharanurak, K., Nishikawa, M., Takahashi, Y., Takakura, Y., Mitani, S., Fujigaki, H., Ohta, Y., Kubo, H., Mamiya, T., Nabeshima, T., Kim, H. C., Yamamoto, Y. & Saito, K., 20-07-2016, : : Scientific reports. 6, 29920.

研究成果: Article

Indoleamine-Pyrrole 2,3,-Dioxygenase
Interferons
Kynurenine
Tryptophan
Depression
16 引用 (Scopus)

High serum concentration of L-kynurenine predicts unfavorable outcomes in patients with acute myeloid leukemia

Mabuchi, R., Hara, T., Matsumoto, T., Shibata, Y., Nakamura, N., Nakamura, H., Kitagawa, J., Kanemura, N., Goto, N., Shimizu, M., Ito, H., Yamamoto, Y., Saito, K., Moriwaki, H. & Tsurumi, H., 02-01-2016, : : Leukemia and Lymphoma. 57, 1, p. 92-98 7 p.

研究成果: Article

Kynurenine
Acute Myeloid Leukemia
Serum
Indoleamine-Pyrrole 2,3,-Dioxygenase
Leukocyte Count
7 引用 (Scopus)

The Deficiency of indoleamine 2,3-Dioxygenase aggravates the CCl4 -Induced liver fibrosis in mice

Ogiso, H., Ito, H., Ando, T., Arioka, Y., Kanbe, A., Ando, K., Ishikawa, T., Saito, K., Hara, A., Moriwaki, H., Shimizu, M. & Seishima, M., 09-2016, : : PloS one. 11, 9, e0162183.

研究成果: Article

Indoleamine-Pyrrole 2,3,-Dioxygenase
liver cirrhosis
Liver Cirrhosis
Liver
mice
8 引用 (Scopus)

The role of indoleamine 2,3-dioxygenase in diethylnitrosamine-induced liver carcinogenesis

Shibata, Y., Hara, T., Nagano, J., Nakamura, N., Ohno, T., Ninomiya, S., Ito, H., Tanaka, T., Saito, K., Seishima, M., Shimizu, M., Moriwaki, H. & Tsurumi, H., 04-01-2016, : : PloS one. 11, 1, e0146279.

研究成果: Article

Indoleamine-Pyrrole 2,3,-Dioxygenase
Diethylnitrosamine
Liver
carcinogenesis
Carcinogenesis
2015
7 引用 (Scopus)

Early microlesion of viral encephalitis confirmed by galectin-3 expression after a virus inoculation

Kobayashi, K., Niwa, M., Hoshi, M., Saito, K., Hisamatsu, K., Hatano, Y., Tomita, H., Miyazaki, T. & Hara, A., 01-04-2015, : : Neuroscience Letters. 592, p. 107-112 6 p.

研究成果: Article

Viral Encephalitis
Galectin 3
Encephalomyocarditis virus
Viruses
Virus Diseases
7 引用 (Scopus)

Effects of indoleamine 2,3-dioxygenase inhibitor in non-Hodgkin lymphoma model mice

Nakamura, N., Hara, T., Shimizu, M., Mabuchi, R., Nagano, J., Ohno, T., Kochi, T., Kubota, M., Shirakami, Y., Goto, N., Ito, H., Saito, K., Tanaka, T., Moriwaki, H. & Tsurumi, H., 13-09-2015, : : International Journal of Hematology. 102, 3, p. 327-334 8 p.

研究成果: Article

Indoleamine-Pyrrole 2,3,-Dioxygenase
Non-Hodgkin's Lymphoma
Cyclophosphamide
Kynurenine
Tryptophan
17 引用 (Scopus)

Expression of indoleamine 2,3-dioxygenase in leukemic cells indicates an unfavorable prognosis in acute myeloid leukemia patients with intermediate-risk cytogenetics

Fukuno, K., Hara, T., Tsurumi, H., Shibata, Y., Mabuchi, R., Nakamura, N., Kitagawa, J., Shimizu, M., Ito, H., Saito, K. & Moriwaki, H., 01-05-2015, : : Leukemia and Lymphoma. 56, 5, p. 1398-1405 8 p.

研究成果: Article

Indoleamine-Pyrrole 2,3,-Dioxygenase
Acute Myeloid Leukemia
Cytogenetics
Messenger RNA
Polymerase Chain Reaction
21 引用 (Scopus)

Inhibition of indoleamine 2,3-dioxygenase 1 expression alters immune response in colon tumor microenvironment in mice

Takamatsu, M., Hirata, A., Ohtaki, H., Hoshi, M., Ando, T., Ito, H., Hatano, Y., Tomita, H., Kuno, T., Saito, K., Seishima, M. & Hara, A., 01-08-2015, : : Cancer science. 106, 8, p. 1008-1015 8 p.

研究成果: Article

Indoleamine-Pyrrole 2,3,-Dioxygenase
Tumor Microenvironment
Colon
Neoplasms
Pharmacology
6 引用 (Scopus)

Inhibition of indoleamine 2,3-dioxygenase activity accelerates skin wound healing

Ito, H., Ando, T., Ogiso, H., Arioka, Y., Saito, K. & Seishima, M., 01-06-2015, : : Biomaterials. 53, p. 221-228 8 p.

研究成果: Article

Indoleamine-Pyrrole 2,3,-Dioxygenase
Tryptophan
Wound Healing
Skin
Kynurenine
15 引用 (Scopus)

Inhibition of indoleamine 2,3-dioxygenase activity enhances the anti-tumour effects of a Toll-like receptor 7 agonist in an established cancer model

Ito, H., Ando, T., Arioka, Y., Saito, K. & Seishima, M., 01-04-2015, : : Immunology. 144, 4, p. 621-630 10 p.

研究成果: Article

Toll-Like Receptor 7
Indoleamine-Pyrrole 2,3,-Dioxygenase
imiquimod
Toll-Like Receptors
Neoplasms
2014
Medicine
15 引用 (Scopus)

Blockade of indoleamine 2,3-dioxygenase reduces mortality from peritonitis and sepsis in mice by regulating functions of CD11b+ peritoneal cells

Hoshi, M., Osawa, Y., Ito, H., Ohtaki, H., Ando, T., Takamatsu, M., Hara, A., Saito, K. & Seishima, M., 01-01-2014, : : Infection and Immunity. 82, 11, p. 4487-4495 9 p.

研究成果: Article

Indoleamine-Pyrrole 2,3,-Dioxygenase
Peritonitis
Sepsis
Mortality
Punctures
9 引用 (Scopus)

Effects of upregulated indoleamine 2, 3-dioxygenase 1 by interferon γ gene transfer on interferon γ-mediated antitumor activity

Watcharanurak, K., Zang, L., Nishikawa, M., Yoshinaga, K., Yamamoto, Y., Takahashi, Y., Ando, M., Saito, K., Watanabe, Y. & Takakura, Y., 01-09-2014, : : Gene therapy. 21, 9, p. 794-801 8 p.

研究成果: Article

Indoleamine-Pyrrole 2,3,-Dioxygenase
Interferons
Lewis Lung Carcinoma
Genes
Neoplasms
16 引用 (Scopus)

Effects of various phytochemicals on indoleamine 2,3-dioxygenase 1 activity: Galanal is a novel, competitive inhibitor of the enzyme

Yamamoto, R., Yamamoto, Y., Imai, S., Fukutomi, R., Ozawa, Y., Abe, M., Matuo, Y. & Saito, K., 12-02-2014, : : PloS one. 9, 2, e88789.

研究成果: Article

Indoleamine-Pyrrole 2,3,-Dioxygenase
enzyme inhibitors
Plant Extracts
Phytochemicals
Enzyme Inhibitors