• 8834 引用
  • 48 h指数
1985 …2020

Research output per year

Pureに変更を加えた場合、すぐここに表示されます。

研究成果

フィルター
Article
2020
1 引用 (Scopus)
公開

Indoleamine-2,3-dioxygenase-1 is a molecular target for the protective activity of mood stabilizers against mania-like behavior induced by d-amphetamine

Tran, H. Q., Shin, E. J., Saito, K., Tran, T. V., Phan, D. H., Sharma, N., Kim, D. W., Choi, S. Y., Jeong, J. H., Jang, C. G., Cheong, J. H., Nabeshima, T. & Kim, H. C., 02-2020, : : Food and Chemical Toxicology. 136, 110986.

研究成果: Article

1 引用 (Scopus)

Kynurenine plays an immunosuppressive role in 2,4,6-trinitrobenzene sulfate-induced colitis in mice

Tashita, C., Hoshi, M., Hirata, A., Nakamoto, K., Ando, T., Hattori, T., Yamamoto, Y., Tezuka, H., Tomita, H., Hara, A. & Saito, K., 07-03-2020, : : World Journal of Gastroenterology. 26, 9, p. 918-932 15 p.

研究成果: Article

公開

Kynurenine produced by indoleamine 2,3-dioxygenase 2 exacerbates acute liver injury by carbon tetrachloride in mice

Hoshi, M., Osawa, Y., Nakamoto, K., Morita, N., Yamamoto, Y., Ando, T., Tashita, C., Nabeshima, T. & Saito, K., 30-05-2020, : : Toxicology. 438, 152458.

研究成果: Article

Lithium attenuates d-amphetamine-induced hyperlocomotor activity in mice via inhibition of interaction between cyclooxygenase-2 and indoleamine-2,3-dioxygenase

Phan, D. H., Shin, E. J., Jeong, J. H., Tran, H. Q., Sharma, N., Nguyen, B. T., Jung, T. W., Nah, S. Y., Saito, K., Nabeshima, T. & Kim, H. C., 01-05-2020, : : Clinical and Experimental Pharmacology and Physiology. 47, 5, p. 790-797 8 p.

研究成果: Article

3 引用 (Scopus)

Serum Metabolic Profiles of the Tryptophan-Kynurenine Pathway in the high risk subjects of major depressive disorder

Sakurai, M., Yamamoto, Y., Kanayama, N., Hasegawa, M., Mouri, A., Takemura, M., Matsunami, H., Miyauchi, T., Tokura, T., Kimura, H., Ito, M., Umemura, E., Boku, A. S., Nagashima, W., Tonoike, T., Kurita, K., Ozaki, N., Nabeshima, T. & Saito, K., 01-12-2020, : : Scientific reports. 10, 1, 1961.

研究成果: Article

公開
2019

5-HT 1A receptor agonist 8-OH-DPAT induces serotonergic behaviors in mice via interaction between PKCδ and p47phox

Tran, H. Q., Shin, E. J., Hoai Nguyen, B. C., Phan, D. H., Kang, M. J., Jang, C. G., Jeong, J. H., Nah, S. Y., Mouri, A., Saito, K., Nabeshima, T. & Kim, H. C., 01-01-2019, : : Food and Chemical Toxicology. 123, p. 125-141 17 p.

研究成果: Article

4 引用 (Scopus)

A complementary scheme for automated detection of high-uptake regions on dedicated breast PET and whole-body PET/CT

Minoura, N., Teramoto, A., Ito, A., Yamamuro, O., Nishio, M., Saito, K. & Fujita, H., 01-09-2019, : : Radiological Physics and Technology. 12, 3, p. 260-267 8 p.

研究成果: Article

Alteration of specific cytokine expression patterns in patients with breast cancer

Kawaguchi, K., Sakurai, M., Yamamoto, Y., Suzuki, E., Tsuda, M., Kataoka, T. R., Hirata, M., Nishie, M., Nojiri, T., Kumazoe, M., Saito, K. & Toi, M., 01-12-2019, : : Scientific reports. 9, 1, 2924.

研究成果: Article

公開
3 引用 (Scopus)
公開

Automated classification of benign and malignant cells from lung cytological images using deep convolutional neural network

Teramoto, A., Yamada, A., Kiriyama, Y., Tsukamoto, T., Yan, K., Zhang, L., Imaizumi, K., Saito, K. & Fujita, H., 2019, : : Informatics in Medicine Unlocked. 16, 100205.

研究成果: Article

公開
6 引用 (Scopus)
11 引用 (Scopus)

Changes in tryptophan metabolism during pregnancy and postpartum periods: Potential involvement in postpartum depressive symptoms

Teshigawara, T., Mouri, A., Kubo, H., Nakamura, Y., Shiino, T., Okada, T., Morikawa, M., Nabeshima, T., Ozaki, N., Yamamoto, Y. & Saito, K., 01-08-2019, : : Journal of Affective Disorders. 255, p. 168-176 9 p.

研究成果: Article

1 引用 (Scopus)

Changes of liver fibrosis markers in patients with treatment by antiviral therapy

Ishidalr, H., Suetsugu, A., Furuta, N., Nohisa, Y., Takemura, M., Saito, K., Shirakam, Y. & Itou, H., 04-2019, : : Japanese Journal of Clinical Chemistry. 48, 2, p. 137-143 7 p.

研究成果: Article

5 引用 (Scopus)
2 引用 (Scopus)

Decline of plasma concentrations of interleukin-18 in severely malnourished patients with anorexia nervosa: Exploratory analysis

Tanaka, S., Oya-Ito, T., Murakami, Y., Saito, K., Furuta, S., Yu, Y., Imaeda, M., Kunimoto, S. & Ozaki, N., 03-2019, : : Nutrients. 11, 3, 540.

研究成果: Article

公開
1 引用 (Scopus)

Effect of antidepressant treatment on plasma levels of neuroinflammation-associated molecules in patients with somatic symptom disorder with predominant pain around the orofacial region

Miyauchi, T., Tokura, T., Kimura, H., Ito, M., Umemura, E., Sato (Boku), A., Nagashima, W., Tonoike, T., Yamamoto, Y., Saito, K., Kurita, K. & Ozaki, N., 07-2019, : : Human Psychopharmacology. 34, 4, e2698.

研究成果: Article

公開
2 引用 (Scopus)

Indoleamine 2,3-dioxygenase 2 depletion suppresses tumor growth in a mouse model of Lewis lung carcinoma

Yamasuge, W., Yamamoto, Y., Fujigaki, H., Hoshi, M., Nakamoto, K., Kunisawa, K., Mouri, A., Nabeshima, T. & Saito, K., 01-10-2019, : : Cancer science. 110, 10, p. 3061-3067 7 p.

研究成果: Article

公開

Selective and competitive inhibition of kynurenine aminotransferase 2 by glycyrrhizic acid and its analogues

Yoshida, Y., Fujigaki, H., Kato, K., Yamazaki, K., Fujigaki, S., Kunisawa, K., Yamamoto, Y., Mouri, A., Oda, A., Nabeshima, T. & Saito, K., 01-12-2019, : : Scientific reports. 9, 1, 10243.

研究成果: Article

公開
1 引用 (Scopus)
2018

Astroglial major histocompatibility complex class I following immune activation leads to behavioral and neuropathological changes

Sobue, A., Ito, N., Nagai, T., Shan, W., Hada, K., Nakajima, A., Murakami, Y., Mouri, A., Yamamoto, Y., Nabeshima, T., Saito, K. & Yamada, K., 05-2018, : : GLIA. 66, 5, p. 1034-1052 19 p.

研究成果: Article

14 引用 (Scopus)
10 引用 (Scopus)

Higher levels of progranulin in cerebrospinal fluid of patients with lymphoma and carcinoma with CNS metastasis

Kimura, A., Takemura, M., Serrero, G., Yoshikura, N., Hayashi, Y., Saito, K. & Inuzuka, T., 01-05-2018, : : Journal of Neuro-Oncology. 137, 3, p. 455-462 8 p.

研究成果: Article

3 引用 (Scopus)

IL-6 knockout mice are protected from cocaine-induced kindling behaviors; possible involvement of JAK2/STAT3 and PACAP signalings

Mai, H. N., Chung, Y. H., Shin, E. J., Sharma, N., Jeong, J. H., Jang, C. G., Saito, K., Nabeshima, T., Reglodi, D. & Kim, H. C., 01-06-2018, : : Food and Chemical Toxicology. 116, p. 249-263 15 p.

研究成果: Article

7 引用 (Scopus)
3 引用 (Scopus)

PKCδ Knockout Mice Are Protected from Dextromethorphan-Induced Serotonergic Behaviors in Mice: Involvements of Downregulation of 5-HT1A Receptor and Upregulation of Nrf2-Dependent GSH Synthesis

Tran, H. Q., Lee, Y., Shin, E. J., Jang, C. G., Jeong, J. H., Mouri, A., Saito, K., Nabeshima, T. & Kim, H. C., 01-10-2018, : : Molecular Neurobiology. 55, 10, p. 7802-7821 20 p.

研究成果: Article

9 引用 (Scopus)
2017

Absence of kynurenine 3-monooxygenase reduces mortality of acute viral myocarditis in mice

Kubo, H., Hoshi, M., Mouri, A., Tashita, C., Yamamoto, Y., Nabeshima, T. & Saito, K., 01-01-2017, : : Immunology Letters. 181, p. 94-100 7 p.

研究成果: Article

8 引用 (Scopus)

Association between increased serum GP88 (progranulin) concentrations and prognosis in patients with malignant lymphomas

Yamamoto, Y., Goto, N., Takemura, M., Yamasuge, W., Yabe, K., Takami, T., Miyazaki, T., Takeuchi, T., Shiraki, M., Shimizu, M., Adachi, S., Saito, K., Shibata, Y., Nakamura, N., Hara, T., Serrero, G., Saito, K. & Tsurumi, H., 10-2017, : : Clinica Chimica Acta. 473, p. 139-146 8 p.

研究成果: Article

10 引用 (Scopus)

Association between naturally occurring anti-amyloid β autoantibodies and medial temporal lobe atrophy in Alzheimer's disease

Kimura, A., Takemura, M., Saito, K., Yoshikura, N., Hayashi, Y. & Inuzuka, T., 01-02-2017, : : Journal of Neurology, Neurosurgery and Psychiatry. 88, 2, p. 126-131 6 p.

研究成果: Article

5 引用 (Scopus)

Comparison of cerebrospinal fluid profiles in Alzheimer’s disease with multiple cerebral microbleeds and cerebral amyloid angiopathy-related inflammation

Kimura, A., Takemura, M., Saito, K., Yoshikura, N., Hayashi, Y., Harada, N., Nishida, H., Nakajima, H. & Inuzuka, T., 01-02-2017, : : Journal of Neurology. 264, 2, p. 373-381 9 p.

研究成果: Article

4 引用 (Scopus)

Effect of water-immersion restraint stress on tryptophan catabolism through the kynurenine pathway in rat tissues

Ohta, Y., Kubo, H., Yashiro, K., Ohashi, K., Tsuzuki, Y., Wada, N., Yamamoto, Y. & Saito, K., 01-05-2017, : : Journal of Physiological Sciences. 67, 3, p. 361-372 12 p.

研究成果: Article

9 引用 (Scopus)

Increased cerebrospinal fluid progranulin correlates with interleukin-6 in the acute phase of neuromyelitis optica spectrum disorder

Kimura, A., Takemura, M., Saito, K., Serrero, G., Yoshikura, N., Hayashi, Y. & Inuzuka, T., 15-04-2017, : : Journal of Neuroimmunology. 305, p. 175-181 7 p.

研究成果: Article

9 引用 (Scopus)
10 引用 (Scopus)

Sake lees extract improves hepatic lipid accumulation in high fat diet-fed mice

Kubo, H., Hoshi, M., Matsumoto, T., Irie, M., Oura, S., Tsutsumi, H., Hata, Y., Yamamoto, Y. & Saito, K., 03-06-2017, : : Lipids in Health and Disease. 16, 1, 106.

研究成果: Article

4 引用 (Scopus)

Serum concentrations of l-kynurenine predict clinical outcomes of patients with peripheral T-cell lymphoma, not otherwise specified

Shibata, Y., Hara, T., Matsumoto, T., Nakamura, N., Nakamura, H., Ninomiya, S., Kitagawa, J., Goto, N., Nannya, Y., Ito, H., Kito, Y., Miyazaki, T., Takeuchi, T., Saito, K., Seishima, M., Takami, T., Moriwaki, H., Shimizu, M. & Tsurumi, H., 12-2017, : : Hematological Oncology. 35, 4, p. 637-644 8 p.

研究成果: Article

Depressive symptoms as a side effect of Interferon-α therapy induced by induction of indoleamine 2,3-dioxygenase 1

Murakami, Y., Ishibashi, T., Tomita, E., Imamura, Y., Tashiro, T., Watcharanurak, K., Nishikawa, M., Takahashi, Y., Takakura, Y., Mitani, S., Fujigaki, H., Ohta, Y., Kubo, H., Mamiya, T., Nabeshima, T., Kim, H. C., Yamamoto, Y. & Saito, K., 20-07-2016, : : Scientific reports. 6, 29920.

研究成果: Article

23 引用 (Scopus)

High serum concentration of L-kynurenine predicts unfavorable outcomes in patients with acute myeloid leukemia

Mabuchi, R., Hara, T., Matsumoto, T., Shibata, Y., Nakamura, N., Nakamura, H., Kitagawa, J., Kanemura, N., Goto, N., Shimizu, M., Ito, H., Yamamoto, Y., Saito, K., Moriwaki, H. & Tsurumi, H., 02-01-2016, : : Leukemia and Lymphoma. 57, 1, p. 92-98 7 p.

研究成果: Article

18 引用 (Scopus)

The Deficiency of indoleamine 2,3-Dioxygenase aggravates the CCl4 -Induced liver fibrosis in mice

Ogiso, H., Ito, H., Ando, T., Arioka, Y., Kanbe, A., Ando, K., Ishikawa, T., Saito, K., Hara, A., Moriwaki, H., Shimizu, M. & Seishima, M., 09-2016, : : PloS one. 11, 9, e0162183.

研究成果: Article

9 引用 (Scopus)

The role of indoleamine 2,3-dioxygenase in diethylnitrosamine-induced liver carcinogenesis

Shibata, Y., Hara, T., Nagano, J., Nakamura, N., Ohno, T., Ninomiya, S., Ito, H., Tanaka, T., Saito, K., Seishima, M., Shimizu, M., Moriwaki, H. & Tsurumi, H., 04-01-2016, : : PloS one. 11, 1, e0146279.

研究成果: Article

8 引用 (Scopus)
2015

Early microlesion of viral encephalitis confirmed by galectin-3 expression after a virus inoculation

Kobayashi, K., Niwa, M., Hoshi, M., Saito, K., Hisamatsu, K., Hatano, Y., Tomita, H., Miyazaki, T. & Hara, A., 01-04-2015, : : Neuroscience Letters. 592, p. 107-112 6 p.

研究成果: Article

8 引用 (Scopus)

Effects of indoleamine 2,3-dioxygenase inhibitor in non-Hodgkin lymphoma model mice

Nakamura, N., Hara, T., Shimizu, M., Mabuchi, R., Nagano, J., Ohno, T., Kochi, T., Kubota, M., Shirakami, Y., Goto, N., Ito, H., Saito, K., Tanaka, T., Moriwaki, H. & Tsurumi, H., 13-09-2015, : : International Journal of Hematology. 102, 3, p. 327-334 8 p.

研究成果: Article

8 引用 (Scopus)

Expression of indoleamine 2,3-dioxygenase in leukemic cells indicates an unfavorable prognosis in acute myeloid leukemia patients with intermediate-risk cytogenetics

Fukuno, K., Hara, T., Tsurumi, H., Shibata, Y., Mabuchi, R., Nakamura, N., Kitagawa, J., Shimizu, M., Ito, H., Saito, K. & Moriwaki, H., 01-05-2015, : : Leukemia and Lymphoma. 56, 5, p. 1398-1405 8 p.

研究成果: Article

22 引用 (Scopus)

Inhibition of indoleamine 2,3-dioxygenase 1 expression alters immune response in colon tumor microenvironment in mice

Takamatsu, M., Hirata, A., Ohtaki, H., Hoshi, M., Ando, T., Ito, H., Hatano, Y., Tomita, H., Kuno, T., Saito, K., Seishima, M. & Hara, A., 01-08-2015, : : Cancer science. 106, 8, p. 1008-1015 8 p.

研究成果: Article

24 引用 (Scopus)

Inhibition of indoleamine 2,3-dioxygenase activity accelerates skin wound healing

Ito, H., Ando, T., Ogiso, H., Arioka, Y., Saito, K. & Seishima, M., 01-06-2015, : : Biomaterials. 53, p. 221-228 8 p.

研究成果: Article

6 引用 (Scopus)