Atsuko Niimi

2023

LASP1, CERS6, and Actin Form a Ternary Complex That Promotes Cancer Cell Migration

Niimi, A., Limsirichaikul, S., Kano, K., Mizutani, Y., Takeuchi, T., Sawangsri, P., Tran, D. Q., Kawamoto, Y. & Suzuki, M., 05-2023, In: Cancers. 15, 10, 2781.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

2 被引用数 (Scopus)

2022

Alanine-Serine-Cysteine Transporter 2 Inhibition Suppresses Prostate Cancer Cell Growth In Vitro

Saruta, M., Takahara, K., Yoshizawa, A., Niimi, A., Takeuchi, T., Nukaya, T., Takenaka, M., Zennami, K., Ichino, M., Sasaki, H., Kusaka, M., Suzuki, M., Sumitomo, M. & Shiroki, R., 09-2022, In: Journal of Clinical Medicine. 11, 18, 5466.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

1 被引用数 (Scopus)

Antitumor effect of polyphyllin D on liver metastases of neuroblastoma

Kondo, Y., Watanabe, S., Naoe, A., Takeuchi, T., Niimi, A., Suzuki, M., Asai, N., Okada, S., Tsuchiya, T., Murayama, M., Yasui, T., Inoue, M. & Suzuki, T., 08-2022, In: Pediatric Surgery International. 38, 8, p. 1157-1163 7 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

1 被引用数 (Scopus)

Enzyme-labeled Antigen Method: Factors Influencing the Deterioration of Antigen-binding Activity of Specific Antibodies during Formalin Fixation and Paraffin Embedding

Mizutani, Y., Shiogama, K., Inada, K. I., Takeuchi, T., Niimi, A., Suzuki, M. & Tsutsumi, Y., 2022, In: Acta Histochemica et Cytochemica. 55, 5, p. 129-148 20 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

2021

CEBPγ facilitates lamellipodia formation and cancer cell migration through CERS6 upregulation

Shi, H., Niimi, A., Takeuchi, T., Shiogama, K., Mizutani, Y., Kajino, T., Inada, K., Hase, T., Hatta, T., Shibata, H., Fukui, T., Chen-Yoshikawa, T. F., Nagano, K., Murate, T., Kawamoto, Y., Tomida, S., Takahashi, T. & Suzuki, M., 07-2021, In: Cancer science. 112, 7, p. 2770-2780 11 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

9 被引用数 (Scopus)

Combined α-methylacyl-CoA racemase inhibition and docetaxel treatment reduce cell proliferation and decrease expression of heat shock protein 27 in androgen receptor-variant-7–positive prostate cancer cells

Yoshizawa, A., Takahara, K., Saruta, M., Zennami, K., Nukaya, T., Fukaya, K., Ichino, M., Fukami, N., Niimi, A., Sasaki, H., Kusaka, M., Suzuki, M., Sumitomo, M. & Shiroki, R., 03-2021, In: Prostate International. 9, 1, p. 18-24 7 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

5 被引用数 (Scopus)

2020

CERS6 required for cell migration and metastasis in lung cancer

Suzuki, M., Cao, K., Kato, S., Mizutani, N., Tanaka, K., Arima, C., Tai, M. C., Nakatani, N., Yanagisawa, K., Takeuchi, T., Shi, H., Mizutani, Y., Niimi, A., Taniguchi, T., Fukui, T., Yokoi, K., Wakahara, K., Hasegawa, Y., Mizutani, Y. & Iwaki, S. & 7 others, Fujii, S., Satou, A., Tamiya-Koizumi, K., Murate, T., Kyogashima, M., Tomida, S. & Takahashi, T., 01-10-2020, In: Journal of Cellular and Molecular Medicine. 24, 20, p. 11949-11959 11 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

15 被引用数 (Scopus)

2019

Clustered DNA double-strand break formation and the repair pathway following heavy-ion irradiation

Hagiwara, Y., Oike, T., Niimi, A., Yamauchi, M., Sato, H., Limsirichaikul, S., Held, K. D., Nakano, T. & Shibata, A., 01-01-2019, In: Journal of Radiation Research. 60, 1, p. 69-79 11 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

63 被引用数 (Scopus)

2018

Analysis of programmed death-ligand 1 expression in primary normal human dermal fibroblasts after DNA damage

Hagiwara, Y., Sato, H., Permata, T. B. M., Niimi, A., Yamauchi, M., Oike, T., Nakano, T. & Shibata, A., 08-2018, In: Human Immunology. 79, 8, p. 627-631 5 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

7 被引用数 (Scopus)

2017

3D-structured illumination microscopy reveals clustered DNA double-strand break formation in widespread γH2AX foci after high LET heavy-ion particle radiation

Hagiwara, Y., Niimi, A., Isono, M., Yamauchi, M., Yasuhara, T., Limsirichaikul, S., Oike, T., Sato, H., Held, K. D., Nakano, T. & Shibata, A., 2017, In: Oncotarget. 8, 65, p. 109370-109381 12 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

47 被引用数 (Scopus)

BRCA1 Directs the Repair Pathway to Homologous Recombination by Promoting 53BP1 Dephosphorylation

Isono, M., Niimi, A., Oike, T., Hagiwara, Y., Sato, H., Sekine, R., Yoshida, Y., Isobe, S. Y., Obuse, C., Nishi, R., Petricci, E., Nakada, S., Nakano, T. & Shibata, A., 10-01-2017, In: Cell Reports. 18, 2, p. 520-532 13 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

135 被引用数 (Scopus)

DNA double-strand break repair pathway regulates PD-L1 expression in cancer cells

Sato, H., Niimi, A., Yasuhara, T., Permata, T. B. M., Hagiwara, Y., Isono, M., Nuryadi, E., Sekine, R., Oike, T., Kakoti, S., Yoshimoto, Y., Held, K. D., Suzuki, Y., Kono, K., Miyagawa, K., Nakano, T. & Shibata, A., 01-12-2017, In: Nature communications. 8, 1, 1751.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

504 被引用数 (Scopus)

Inhibition of the HDAC/Suv39/G9a pathway restores the expression of DNA damage-dependent major histocompatibility complex class I-related chain A and B in cancer cells

Nakajima, N. I., Niimi, A., Isono, M., Oike, T., Sato, H., Nakano, T. & Shibata, A., 08-2017, In: Oncology reports. 38, 2, p. 693-702 10 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

25 被引用数 (Scopus)

Mitotic catastrophe is a putative mechanism underlying the weak correlation between sensitivity to carbon ions and cisplatin

Kobayashi, D., Oike, T., Shibata, A., Niimi, A., Kubota, Y., Sakai, M., Amornwhichet, N., Yoshimoto, Y., Hagiwara, Y., Kimura, Y., Hirota, Y., Sato, H., Isono, M., Yoshida, Y., Kohno, T., Ohno, T. & Nakano, T., 16-01-2017, In: Scientific reports. 7, 40588.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

27 被引用数 (Scopus)

Regulation of pairing between broken DNA-containing chromatin regions by Ku80, DNA-PKcs, ATM, and 53BP1

Yamauchi, M., Shibata, A., Suzuki, K., Suzuki, M., Niimi, A., Kondo, H., Miura, M., Hirakawa, M., Tsujita, K., Yamashita, S. & Matsuda, N., 03-02-2017, In: Scientific reports. 7, 41812.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

14 被引用数 (Scopus)

2016

Identification of DNA double strand breaks at chromosome boundaries along the track of particle irradiation

Niimi, A., Yamauchi, M., Limsirichaikul, S., Sekine, R., Oike, T., Sato, H., Suzuki, K., Held, K. D., Nakano, T. & Shibata, A., 01-08-2016, In: Genes Chromosomes and Cancer. 55, 8, p. 650-660 11 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

8 被引用数 (Scopus)

Visualization of complex DNA double-strand breaks in a tumor treated with carbon ion radiotherapy

Oike, T., Niimi, A., Okonogi, N., Murata, K., Matsumura, A., Noda, S. E., Kobayashi, D., Iwanaga, M., Tsuchida, K., Kanai, T., Ohno, T., Shibata, A. & Nakano, T., 01-03-2016, In: Scientific reports. 6, 22275.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

53 被引用数 (Scopus)

2015

The BAH domain of BAF180 is required for PCNA ubiquitination

Niimi, A., Hopkins, S. R., Downs, J. A. & Masutani, C., 01-09-2015, In: Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 779, p. 16-23 8 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

15 被引用数 (Scopus)

2013

Firefly luciferase as the reporter for transcriptional response to the environment in Escherichia coli

Ryo, M., Oshikoshi, Y., Doi, S., Motoki, S., Niimi, A. & Aoki, S., 2013, In: Analytical Biochemistry. 443, 2, p. 211-213 3 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

1 被引用数 (Scopus)

2012

A role for chromatin remodellers in replication of damaged DNA

Niimi, A., Chambers, A. L., Downs, J. A. & Lehmann, A. R., 08-2012, In: Nucleic acids research. 40, 15, p. 7393-7403 11 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

45 被引用数 (Scopus)

2010

Functions of base selection step in human DNA polymerase α

Tanaka, S., Cao, K., Niimi, A., Limsirichaikul, S., Miao, H. Q., Nakamura, N., Murate, T., Hasegawa, Y., Takahashi, T. & Suzuki, M., 04-05-2010, In: DNA Repair. 9, 5, p. 534-541 8 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

10 被引用数 (Scopus)

Regulation of Translesion Synthesis DNA Polymerase η by Monoubiquitination

Bienko, M., Green, C. M., Sabbioneda, S., Crosetto, N., Matic, I., Hibbert, R. G., Begovic, T., Niimi, A., Mann, M., Lehmann, A. R. & Dikic, I., 12-02-2010, In: Molecular Cell. 37, 3, p. 396-407 12 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

141 被引用数 (Scopus)

Three DNA Polymerases, Recruited by Different Mechanisms, Carry Out NER Repair Synthesis in Human Cells

Ogi, T., Limsirichaikul, S., Overmeer, R. M., Volker, M., Takenaka, K., Cloney, R., Nakazawa, Y., Niimi, A., Miki, Y., Jaspers, N. G., Mullenders, L. H. F., Yamashita, S., Fousteri, M. I. & Lehmann, A. R., 12-03-2010, In: Molecular Cell. 37, 5, p. 714-727 14 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

295 被引用数 (Scopus)

2009

A rapid non-radioactive technique for measurement of repair synthesis in primary human fibroblasts by incorporation of ethynyl deoxyuridine (EdU)

Limsirichaikul, S., Niimi, A., Fawcett, H., Lehmann, A., Yamashita, S. & Ogi, T., 2009, In: Nucleic acids research. 37, 4, e31.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

97 被引用数 (Scopus)

PCNA mono-ubiquitination and activation of translesion DNA polymerases by DNA polymerase α

Suzuki, M., Niimi, A., Limsirichaikul, S., Tomida, S., Miao Huang, Q., Izuta, S., Usukura, J., Itoh, Y., Hishida, T., Akashi, T., Nakagawa, Y., Kikuchi, A., Pavlov, Y., Murate, T. & Takahashi, T., 07-2009, In: Journal of Biochemistry. 146, 1, p. 13-21 9 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

12 被引用数 (Scopus)

2008

Regulation of proliferating cell nuclear antigen ubiquitination in mammalian cells

Niimi, A., Brown, S., Sabbioneda, S., Kannouche, P. L., Scott, A., Yasui, A., Green, C. M. & Lehmann, A. R., 21-10-2008, In: Proceedings of the National Academy of Sciences of the United States of America. 105, 42, p. 16125-16130 6 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

151 被引用数 (Scopus)

2007

Inhibitors of the proteasome suppress homologous DNA recombination in mammalian cells

Murakawa, Y., Sonoda, E., Barber, L. J., Zeng, W., Yokomori, K., Kimura, H., Niimi, A., Lehmann, A., Guang, Y. Z., Hochegger, H., Boulton, S. J. & Takeda, S., 15-09-2007, In: Cancer Research. 67, 18, p. 8536-8543 8 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

94 被引用数 (Scopus)

Translesion synthesis: Y-family polymerases and the polymerase switch

Lehmann, A. R., Niimi, A., Ogi, T., Brown, S., Sabbioneda, S., Wing, J. F., Kannouche, P. L. & Green, C. M., 01-07-2007, In: DNA Repair. 6, 7, p. 891-899 9 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

330 被引用数 (Scopus)

2006

Evidence that errors made by DNA polymerase α are corrected by DNA polymerase δ

Pavlov, Y. I., Frahm, C., McElhinny, S. A. N., Niimi, A., Suzuki, M. & Kunkel, T. A., 24-01-2006, In: Current Biology. 16, 2, p. 202-207 6 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

147 被引用数 (Scopus)

2004

Palm Mutants in DNA Polymerases α and η Alter DNA Replication Fidelity and Translesion Activity

Niimi, A., Limsirichaikul, S., Yoshida, S., Iwai, S., Masutani, C., Hanaoka, F., Kool, E. T., Nishiyama, Y. & Suzuki, M., 04-2004, In: Molecular and Cellular Biology. 24, 7, p. 2734-2746 13 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

75 被引用数 (Scopus)

2003

Distinct function of conserved amino acids in the fingers of Saccharomyces cerevisiae DNA polymerase α

Ogawa, M., Limsirichaikul, S., Niimi, A., Iwai, S., Yoshida, S. & Suzuki, M., 23-05-2003, In: Journal of Biological Chemistry. 278, 21, p. 19071-19078 8 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

15 被引用数 (Scopus)

The Gly-952 residue of Saccharomyces cerevisiae DNA polymerase α is important in discriminating correct deoxyribonucleotides from incorrect ones

Limsirichaikul, S., Ogawa, M., Niimi, A., Iwai, S., Murate, T., Yoshida, S. & Suzuki, M., 23-05-2003, In: Journal of Biological Chemistry. 278, 21, p. 19079-19086 8 p.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

Open Access

7 被引用数 (Scopus)

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