• 4981 引用
  • 33 h指数
1989 …2018

年単位の研究成果

Pureに変更を加えた場合、すぐここに表示されます。

研究成果

  • 4981 引用
  • 33 h指数
  • 73 Article
  • 2 Review article
  • 1 Comment/debate
フィルター
Article
2017
15 引用 (Scopus)
2016
17 引用 (Scopus)
2014

Intravenous administration of Bone marrow mononuclear cells alleviates hearing loss after transient cochlear ischemia through paracrine effects

Takagi, T., Yoshida, T., Okada, M., Hata, R., Hato, N., Gyo, K. & Hakuba, N., 01-01-2014, : : Neuroreport. 25, 11, p. 807-813 7 p.

研究成果: Article

2013

Modeling Alzheimer's disease with iPSCs reveals stress phenotypes associated with intracellular Aβ and differential drug responsiveness

Kondo, T., Asai, M., Tsukita, K., Kutoku, Y., Ohsawa, Y., Sunada, Y., Imamura, K., Egawa, N., Yahata, N., Okita, K., Takahashi, K., Asaka, I., Aoi, T., Watanabe, A., Watanabe, K., Kadoya, C., Nakano, R., Watanabe, D., Maruyama, K., Hori, O. および23人, Hibino, S., Choshi, T., Nakahata, T., Hioki, H., Kaneko, T., Naitoh, M., Yoshikawa, K., Yamawaki, S., Suzuki, S., Hata, R., Ueno, S. I., Seki, T., Kobayashi, K., Toda, T., Murakami, K., Irie, K., Klein, W. L., Mori, H., Asada, T., Takahashi, R., Iwata, N., Yamanaka, S. & Inoue, H., 04-04-2013, : : Cell Stem Cell. 12, 4, p. 487-496 10 p.

研究成果: Article

437 引用 (Scopus)
2012

Targeted disruption of organic cation transporter 3 (Oct3) ameliorates ischemic brain damage through modulating histamine and regulatory T cells

Zhu, P., Hata, R., Ogasawara, M., Cao, F., Kameda, K., Yamauchi, K., Schinkel, A. H., Maeyama, K. & Sakanaka, M., 10-2012, : : Journal of Cerebral Blood Flow and Metabolism. 32, 10, p. 1897-1908 12 p.

研究成果: Article

16 引用 (Scopus)
2011

Reduced ischemic brain injury by partial rejuvenation of bone marrow cells in aged rats

Taguchi, A., Zhu, P., Cao, F., Kikuchi-Taura, A., Kasahara, Y., Stern, D. M., Soma, T., Matsuyama, T. & Hata, R., 01-03-2011, : : Journal of Cerebral Blood Flow and Metabolism. 31, 3, p. 855-867 13 p.

研究成果: Article

22 引用 (Scopus)

Risk of progression from mild memory impairment to clinically diagnosable Alzheimer's disease in a Japanese community (from the Nakayama Study)

Sonobe, N., Hata, R., Ishikawa, T., Sonobe, K., Matsumoto, T., Toyota, Y., Mori, T., Fukuhara, R., Komori, K., Ueno, S. I., Tanimukai, S. & Ikeda, M., 06-2011, : : International Psychogeriatrics. 23, 5, p. 772-779 8 p.

研究成果: Article

3 引用 (Scopus)
2010

Conditional deletion of Stat3 promotes neurogenesis and inhibits astrogliogenesis in neural stem cells

Cao, F., Hata, R., Zhu, P., Nakashiro, K. I. & Sakanaka, M., 09-04-2010, : : Biochemical and Biophysical Research Communications. 394, 3, p. 843-847 5 p.

研究成果: Article

54 引用 (Scopus)

Delayed neuronal cell death in brainstem after transient brainstem ischemia in gerbils

Cao, F., Hata, R., Zhu, P., Takeda, S., Yoshida, T., Hakuba, N., Sakanaka, M. & Gyo, K., 14-09-2010, : : BMC Neuroscience. 11, 115.

研究成果: Article

3 引用 (Scopus)
2009

Ischemic tolerance in the cochlea

Takeda, S., Hata, R., Cao, F., Yoshida, T., Hakuba, N., Hato, N. & Gyo, K., 25-09-2009, : : Neuroscience Letters. 462, 3, p. 263-266 4 p.

研究成果: Article

5 引用 (Scopus)

Up-regulation of syntaxin1 in ischemic cortex after permanent focal ischemia in rats

Cao, F., Hata, R., Zhu, P., Niinobe, M. & Sakanaka, M., 26-05-2009, : : Brain Research. 1272, p. 52-61 10 p.

研究成果: Article

10 引用 (Scopus)
2008

Postischemic mild hypothermia alleviates hearing loss because of transient ischemia

Takeda, S., Hakuba, N., Yoshida, T., Fujita, K., Hato, N., Hata, R., Hyodo, J. & Gyo, K., 27-08-2008, : : Neuroreport. 19, 13, p. 1325-1328 4 p.

研究成果: Article

6 引用 (Scopus)

Ramified microglial cells promote astrogliogenesis and maintenance of neural stem cells through activation of Stat3 function

Zhu, P., Hata, R., Cao, F., Gu, F., Hanakawa, Y., Hashimoto, K. & Sakanaka, M., 01-11-2008, : : FASEB Journal. 22, 11, p. 3866-3877 12 p.

研究成果: Article

41 引用 (Scopus)
2007

Ginsenoside Rb1 protects against damage to the spiral ganglion cells after cochlear ischemia

Fujita, K., Hakuba, N., Hata, R., Morizane, I., Yoshida, T., Shudou, M., Sakanaka, M. & Gyo, K., 26-03-2007, : : Neuroscience Letters. 415, 2, p. 113-117 5 p.

研究成果: Article

39 引用 (Scopus)

Hematopoietic stem cells prevent hair cell death after transient cochlear ischemia through paracrine effects

Yoshida, T., Hata, R., Hakuba, N., Cao, F., Zhu, P., Sakanaka, M. & Gyo, K., 13-11-2007, : : Journal of Cerebral Blood Flow and Metabolism. 27, SUPPL. 1, p. BP27-07H

研究成果: Article

Hematopoietic stem cells prevent hair cell death after transient cochlear ischemia through paracrine effects

Yoshida, T., Hakuba, N., Morizane, I., Fujita, K., Cao, F., Zhu, P., Uchida, N., Kameda, K., Sakanaka, M., Gyo, K. & Hata, R., 30-03-2007, : : Neuroscience. 145, 3, p. 923-930 8 p.

研究成果: Article

25 引用 (Scopus)

Intravenous infusion of dihydroginsenoside Rb1 prevents compressive spinal cord injury and ischemic brain damage through upregulation of VEGF and Bcl-xL

Sakanaka, M., Zhu, P., Zhang, B., Wen, T. C., Cao, F., Ma, Y. J., Samukawa, K., Mitsuda, N., Tanaka, J., Kuramoto, M., Uno, H. & Hata, R., 01-06-2007, : : Journal of Neurotrauma. 24, 6, p. 1037-1054 18 p.

研究成果: Article

38 引用 (Scopus)

Overexpression of Stat3 promotes neuronal cell death through activation of microglia

Hata, R., Zhu, P., Cao, F. & Sakanaka, M., 13-11-2007, : : Journal of Cerebral Blood Flow and Metabolism. 27, SUPPL. 1, p. BO04-02

研究成果: Article

2006

Overexpression of SOCS3 inhibits astrogliogenesis and promotes maintenance of neural stem cells

Cao, F., Hata, R., Zhu, P., Ma, Y. J., Tanaka, J., Hanakawa, Y., Hashimoto, K., Niinobe, M., Yoshikawa, K. & Sakanaka, M., 07-2006, : : Journal of neurochemistry. 98, 2, p. 459-470 12 p.

研究成果: Article

30 引用 (Scopus)

Prevention of ischemic neuronal death by intravenous infusion of a ginseng saponin, ginsenoside Rb1, that upregulates Bcl-xL expression

Zhang, B., Hata, R., Zhu, P., Sato, K., Wen, T. C., Yang, L., Fujita, H., Mitsuda, N., Tanaka, J., Samukawa, K., Maeda, N. & Sakanaka, M., 01-05-2006, : : Journal of Cerebral Blood Flow and Metabolism. 26, 5, p. 708-721 14 p.

研究成果: Article

59 引用 (Scopus)
2005

Identification of hippocampus-related candidate genes for Alzheimer's disease

Taguchi, K., Yamagata, H. D., Zhong, W., Kamino, K., Akatsu, H., Hata, R., Yamamoto, T., Kosaka, K., Takeda, M., Kondo, I. & Miki, T., 01-04-2005, : : Annals of Neurology. 57, 4, p. 585-588 4 p.

研究成果: Article

32 引用 (Scopus)

Neural stem cells suppress the hearing threshold shift caused by cochlear ischemia

Hakuba, N., Hata, R., Morizane, I., Feng, G., Shimizu, Y., Fujita, K., Yoshida, T., Sakanaka, M. & Gyo, K., 28-09-2005, : : NeuroReport. 16, 14, p. 1545-1549 5 p.

研究成果: Article

30 引用 (Scopus)

Suppression of Stat3 promotes neurogenesis in cultured neural stem cells

Gu, F., Hata, R., Ma, Y. J., Tanaka, J., Mitsuda, N., Kumon, Y., Hanakawa, Y., Hashimoto, K., Nakajima, K. & Sakanaka, M., 15-07-2005, : : Journal of Neuroscience Research. 81, 2, p. 163-171 9 p.

研究成果: Article

95 引用 (Scopus)
2004

Possible inhibition of focal cerebral ischemia by angiotensin II type 2 receptor stimulation

Iwai, M., Liu, H. W., Chen, R., Ide, A., Okamoto, S., Hata, R., Sakanaka, M., Shiuchi, T. & Horiuchi, M., 17-08-2004, : : Circulation. 110, 7, p. 843-848 6 p.

研究成果: Article

210 引用 (Scopus)

Protective effect of vitamin E against focal brain ischemia and neuronal death through induction of target genes of hypoxia-inducible factor-1

Zhang, B., Tanaka, J., Yang, L., Yang, L., Sakanaka, M., Hata, R., Maeda, N. & Mitsuda, N., 2004, : : Neuroscience. 126, 2, p. 433-440 8 p.

研究成果: Article

77 引用 (Scopus)
2003

Testosterone up-regulates aquaporin-4 expression in cultured astrocytes

Gu, F., Hata, R., Toku, K., Yang, L., Ma, Y. J., Maeda, N., Sakanaka, M. & Tanaka, J., 15-06-2003, : : Journal of Neuroscience Research. 72, 6, p. 709-715 7 p.

研究成果: Article

52 引用 (Scopus)
2002

Characterizing CGI-94 (comparative gene identification-94) which is down-regulated in the hippocampus of early stage Alzheimer's disease brain

Heese, K., Nakayama, T., Hata, R., Masumura, M., Akatsu, H., Li, F., Nagai, Y., Yamamoto, T., Kosaka, K., Suemoto, T. & Sawada, T., 31-12-2002, : : European Journal of Neuroscience. 15, 1, p. 79-86 8 p.

研究成果: Article

7 引用 (Scopus)

Erythropoietin protects neurons against chemical hypoxia and cerebral ischemic injury by up-regulating Bcl-xL expression

Wen, T. C., Sadamoto, Y., Tanaka, J., Zhu, P. X., Nakata, K., Yong-Jie, M., Hata, R. & Sakanaka, M., 15-03-2002, : : Journal of Neuroscience Research. 67, 6, p. 795-803 9 p.

研究成果: Article

182 引用 (Scopus)
2001

Aggravation of brain injury after transient focal ischemia in p53-deficient mice

Maeda, K., Hata, R., Gillardon, F. & Hossmann, K. A., 31-03-2001, : : Molecular Brain Research. 88, 1-2, p. 54-61 8 p.

研究成果: Article

31 引用 (Scopus)
19 引用 (Scopus)

Gene expressions after thrombolytic treatment of middle cerebral artery clot embolism in mice

Hara, T., Mies, G., Hata, R. & Hossmann, K. A., 01-01-2001, : : Stroke. 32, 8, p. 1912-1919 8 p.

研究成果: Article

13 引用 (Scopus)

Increasing in situ nick end labeling of oligodendrocytes in white matter of patients with Binswanger's disease

Masumura, M., Hata, R., Akatsu, H., Kosaka, K., Yamamoto, T., Nagai, Y. & Sawada, T., 01-01-2001, : : Journal of Stroke and Cerebrovascular Diseases. 10, 2, p. 55-62 8 p.

研究成果: Article

2 引用 (Scopus)

Induction of phosphorylated-Stat3 following focal cerebral ischemia in mice

Wen, T. C., Peng, H., Hata, R., Desaki, J. & Sakanaka, M., 11-05-2001, : : Neuroscience Letters. 303, 3, p. 153-156 4 p.

研究成果: Article

46 引用 (Scopus)

In vivo gene transfer to cerebral white matter lesions with a recombinant adenovirus vector

Masumura, M., Hata, R., Uetsuki, T., Nishimura, I., Nagai, Y. & Sawada, T., 21-09-2001, : : Biochemical and Biophysical Research Communications. 287, 2, p. 440-444 5 p.

研究成果: Article

5 引用 (Scopus)
36 引用 (Scopus)

Protective effect of a prosaposin-derived, 18-mer peptide on slowly progressive neuronal degeneration after brief ischemia

Morita, F., Wen, T. C., Tanaka, J., Hata, R., Desaki, J., Sato, K., Nakata, K., Ma, Y. J. & Sakanaka, M., 01-01-2001, : : Journal of Cerebral Blood Flow and Metabolism. 21, 11, p. 1295-1302 8 p.

研究成果: Article

16 引用 (Scopus)

Relationship between metabolic dysfunctions, gene responses and delayed cell death after mild focal cerebral ischemia in mice

Hermann, D. M., Kilic, E., Hata, R., Hossmann, K. A. & Mies, G., 03-07-2001, : : Neuroscience. 104, 4, p. 947-955 9 p.

研究成果: Article

84 引用 (Scopus)

Up-regulation of calcineurin aβ mRNA in the Alzheimer's disease brain: Assessment by cDNA microarray

Hata, R., Masumura, M., Akatsu, H., Li, F., Fujita, H., Nagai, Y., Yamamoto, T., Okada, H., Kosaka, K., Sakanaka, M. & Sawada, T., 01-01-2001, : : Biochemical and Biophysical Research Communications. 284, 2, p. 310-316 7 p.

研究成果: Article

101 引用 (Scopus)
2000

Altered expression of amyloid precursor proteins after traumatic brain injury in rats: In situ hybridization and immunohistochemical study

Masumura, M., Hata, R., Uramoto, H., Murayama, N., Ohno, T. & Sawada, T., 02-2000, : : Journal of Neurotrauma. 17, 2, p. 123-134 12 p.

研究成果: Article

31 引用 (Scopus)

Caspase-3 activation and inflammatory responses in rat hippocampus inoculated with a recombinant adenovirus expressing the Alzheimer amyloid precursor protein

Masumura, M., Hata, R., Nishimura, I., Uetsuki, T., Sawada, T. & Yoshikawa, K., 15-09-2000, : : Molecular Brain Research. 80, 2, p. 219-227 9 p.

研究成果: Article

37 引用 (Scopus)

Dynamics of regional brain metabolism and gene expression after middle cerebral artery occlusion in mice

Hata, R., Maeda, K., Hermann, D., Mies, G. & Hossmann, K. A., 01-01-2000, : : Journal of Cerebral Blood Flow and Metabolism. 20, 2, p. 306-315 10 p.

研究成果: Article

113 引用 (Scopus)

Evolution of brain infarction after transient focal cerebral ischemia in mice

Hata, R., Maeda, K., Hermann, D., Mies, G. & Hossmann, K. A., 01-01-2000, : : Journal of Cerebral Blood Flow and Metabolism. 20, 6, p. 937-946 10 p.

研究成果: Article

154 引用 (Scopus)

Microglial and astrocytic reactions prior to onset of thalamic cell death after traumatic lesion of the rat sensorimotor cortex

Hermann, D. M., Mies, G., Hata, R. & Hossmann, K. A., 02-2000, : : Acta Neuropathologica. 99, 2, p. 147-153 7 p.

研究成果: Article

21 引用 (Scopus)
1999

Diffusion- and perfusion-weighted MR imaging of transient focal cerebral ischaemia in mice

Van Dorsten, F. A., Hata, R., Maeda, K., Franke, C., Eis, M., Hossmann, K. A. & Hoehn, M., 01-12-1999, : : NMR in Biomedicine. 12, 8, p. 525-534 10 p.

研究成果: Article

48 引用 (Scopus)
60 引用 (Scopus)
54 引用 (Scopus)

Targeted disruption of the bcl-2 gene in mice exacerbates focal ischemic brain injury

Hata, R., Gillardon, F., Michaelidis, T. M. & Hossmann, K. A., 14-09-1999, : : Metabolic Brain Disease. 14, 2, p. 117-124 8 p.

研究成果: Article

71 引用 (Scopus)
1998
29 引用 (Scopus)

Brainstem auditory evoked potentials during brainstem ischemia and reperfusion in gerbils

Hata, R., Matsumoto, M., Matsuyama, T., Yamamoto, K., Hatakeyama, T., Kubo, T., Mikoshiba, K., Sakaki, S., Sugita, M. & Yanagihara, T., 03-1998, : : Neuroscience. 83, 1, p. 201-213 13 p.

研究成果: Article

5 引用 (Scopus)