Takematsu Hiromu

2022

Andrographolide, isolated from Andrographis paniculata, induces apoptosis in monocytic leukemia and multiple myeloma cells via augmentation of reactive oxygen species production

Akiyama, H., Doi, H., Matsui, T., Dijkstra, J. M., Ogasawara, A., Higashimoto, Y., Imamura, S., Ohye, T., Takematsu, H. & Katsuda, I., 2022, In: F1000Research. 10, 542.

研究成果: Article › 査読

Open Access

A Novel Mouse Model of Idiopathic Nephrotic Syndrome Induced by Immunization with the Podocyte Protein Crb2

Hada, I., Shimizu, A., Takematsu, H., Nishibori, Y., Kimura, T., Fukutomi, T., Kudo, A., Ito-Nitta, N., Kiuchi, Z., Patrakka, J., Mikami, N., Leclerc, S., Akimoto, Y., Hirayama, Y., Mori, S., Takano, T. & Yan, K., 11-2022, In: Journal of the American Society of Nephrology. 33, 11, p. 2008-2025 18 p.

研究成果: Article › 査読

2 被引用数 (Scopus)

Coordinated changes in glycosylation regulate the germinal center through CD22

Enterina, J. R., Sarkar, S., Streith, L., Jung, J., Arlian, B. M., Meyer, S. J., Takematsu, H., Xiao, C., Baldwin, T. A., Nitschke, L., Shlomchick, M. J., Paulson, J. C. & Macauley, M. S., 15-03-2022, In: Cell Reports. 38, 11, 110512.

研究成果: Article › 査読

Open Access

2 被引用数 (Scopus)

The inhibitory coreceptor CD22 restores B cell signaling by developmentally regulating Cd45^−/− immunodeficient B cells

Akatsu, C., Deh Sheikh, A. A., Matsubara, N., Takematsu, H., Schweizer, A., Abdu-Allah, H. H. M., Tedder, T. F., Nitschke, L., Ishida, H. & Tsubata, T., 01-03-2022, In: Science Signaling. 15, 723, eabf9570.

研究成果: Article › 査読

USP40 deubiquitinates HINT1 and stabilizes p53 in podocyte damage

Takahashi, S., Fukuhara, D., Kimura, T., Fukutomi, T., Tanaka, E., Mikami, N., Hada, I., Takematsu, H., Nishibori, Y., Akimoto, Y., Kiyonari, H., Abe, T., Huber, O. & Yan, K., 23-07-2022, In: Biochemical and Biophysical Research Communications. 614, p. 198-206 9 p.

研究成果: Article › 査読

2021

A Guillain-Barré syndrome-associated SIGLEC10 rare variant impairs its recognition of gangliosides

Alborzian Deh Sheikh, A., Gomaa, S., Li, X., Routledge, M., Saigoh, K., Numoto, N., Angata, T., Hitomi, Y., Takematsu, H., Tsuiji, M., Ito, N., Kusunoki, S. & Tsubata, T., 01-2021, In: Journal of Autoimmunity. 116, 102571.

研究成果: Article › 査読

7 被引用数 (Scopus)

Andrographolide, isolated from Andrographis paniculata, induces apoptosis in monocytic leukemia and multiple myeloma cells via augmentation of reactive oxygen species production

Doi, H., Matsui, T., Dijkstra, J. M., Ogasawara, A., Higashimoto, Y., Imamura, S., Ohye, T., Takematsu, H., Katsuda, I. & Akiyama, H., 2021, In: F1000Research. 10, p. 542 1 p.

研究成果: Article › 査読

Open Access

1 被引用数 (Scopus)

N-glycolylneuraminic acid in animal models for human influenza a virus

Spruit, C. M., Nemanichvili, N., Okamatsu, M., Takematsu, H., Boons, G. J. & de Vries, R. P., 05-2021, In: Viruses. 13, 5, 815.

研究成果: Article › 査読

Open Access

2 被引用数 (Scopus)

The protein tyrosine phosphatase SHP-1 (PTPN6) but Not CD45 (PTPRC) is essential for the ligand-mediated regulation of CD22 in BCR-ligated b cells

Sheikh, A. A. D., Akatsu, C., Abdu-Allah, H. H. M., Suganuma, Y., Imamura, A., Ando, H., Takematsu, H., Ishida, H. & Tsubata, T., 01-06-2021, In: Journal of Immunology. 206, 11, p. 2544-2551 8 p.

研究成果: Article › 査読

4 被引用数 (Scopus)

2020

Distinct cell surface expression patterns of n-glycosylation site mutants of ampa-type glutamate receptor under the homo-oligomeric expression conditions

Morise, J., Yamamoto, S., Midorikawa, R., Takamiya, K., Nonaka, M., Takematsu, H. & Oka, S., 02-07-2020, In: International journal of molecular sciences. 21, 14, p. 1-11 11 p., 5101.

研究成果: Article › 査読

Open Access

1 被引用数 (Scopus)

2019

AMPA receptors in the synapse turnover by monomer diffusion

Morise, J., Suzuki, K. G. N., Kitagawa, A., Wakazono, Y., Takamiya, K., Tsunoyama, T. A., Nemoto, Y. L., Takematsu, H., Kusumi, A. & Oka, S., 01-12-2019, In: Nature communications. 10, 1, 5245.

研究成果: Article › 査読

Open Access

15 被引用数 (Scopus)

GLCCI1 is a novel protector against glucocorticoid-induced apoptosis in T cells

Kiuchi, Z., Nishibori, Y., Kutsuna, S., Kotani, M., Hada, I., Kimura, T., Fukutomi, T., Fukuhara, D., Ito-Nitta, N., Kudo, A., Takata, T., Ishigaki, Y., Tomosugi, N., Tanaka, H., Matsushima, S., Ogasawara, S., Hirayama, Y., Takematsu, H. & Yan, K., 01-06-2019, In: FASEB Journal. 33, 6, p. 7387-7402 16 p.

研究成果: Article › 査読

9 被引用数 (Scopus)

Site-specific HNK-1 epitope on alternatively spliced fibronectin type-III repeats in tenascin-C promotes neurite outgrowth of hippocampal neurons through contactin-1

Nakamura, A., Morise, J., Yabuno-Nakagawa, K., Hashimoto, Y., Takematsu, H. & Oka, S., 01-2019, In: PloS one. 14, 1, e0210193.

研究成果: Article › 査読

Open Access

7 被引用数 (Scopus)

2018

CD22-binding synthetic sialosides regulate B lymphocyte proliferation through CD22 ligand-dependent and independent pathways, and enhance antibody production in mice

Matsubara, N., Imamura, A., Yonemizu, T., Akatsu, C., Yang, H., Ueki, A., Watanabe, N., Abdu-Allah, H., Numoto, N., Takematsu, H., Kitazume, S., Tedder, T. F., Marth, J. D., Ito, N., Ando, H., Ishida, H., Kiso, M. & Tsubata, T., 19-04-2018, In: Frontiers in Immunology. 9, APR, 820.

研究成果: Article › 査読

Open Access

15 被引用数 (Scopus)

Proximity labeling of cis-ligands of CD22/Siglec-2 reveals stepwise α2,6 sialic acid-dependent and -independent interactions

Alborzian Deh Sheikh, A., Akatsu, C., Imamura, A., Abdu-Allah, H. H. M., Takematsu, H., Ando, H., Ishida, H. & Tsubata, T., 01-01-2018, In: Biochemical and Biophysical Research Communications. 495, 1, p. 854-859 6 p.

研究成果: Article › 査読

16 被引用数 (Scopus)

Ribosomal protein uS7/Rps5 serine-223 in protein kinase-mediated phosphorylation and ribosomal small subunit maturation

Tomioka, M., Shimobayashi, M., Kitabatake, M., Ohno, M., Kozutsumi, Y., Oka, S. & Takematsu, H., 01-12-2018, In: Scientific reports. 8, 1, 1244.

研究成果: Article › 査読

Open Access

6 被引用数 (Scopus)

2017

Ecm33 is a novel factor involved in efficient glucose uptake for nutrition-responsive TORC1 signaling in yeast

Umekawa, M., Ujihara, M., Nakai, D., Takematsu, H. & Wakayama, M., 11-2017, In: FEBS Letters. 591, 22, p. 3721-3729 9 p.

研究成果: Article › 査読

Open Access

7 被引用数 (Scopus)

Physiological exploration of the long term evolutionary selection against expression of N-Glycolylneuraminic Acid in the Brain

Naito-Matsui, Y., Davies, L. R. L., Takematsu, H., Chou, H. H., Tangvoranuntakul, P., Carlin, A. F., Verhagen, A., Heyser, C. J., Yoo, S. W., Choudhury, B., Paton, J. C., Paton, A. W., Varki, N. M., Schnaar, R. L. & Varki, A., 17-02-2017, In: Journal of Biological Chemistry. 292, 7, p. 2557-2570 14 p.

研究成果: Article › 査読

Open Access

26 被引用数 (Scopus)

USP40 gene knockdown disrupts glomerular permeability in zebrafish

Takagi, H., Nishibori, Y., Katayama, K., Katada, T., Takahashi, S., Kiuchi, Z., Takahashi, S. I., Kamei, H., Kawakami, H., Akimoto, Y., Kudo, A., Asanuma, K., Takematsu, H. & Yan, K., 04-2017, In: American Journal of Physiology - Renal Physiology. 312, 4, p. F702-F715

研究成果: Article › 査読

Open Access

8 被引用数 (Scopus)

2016

Psychosine-triggered endomitosis is modulated by membrane sphingolipids through regulation of phosphoinositide 4,5-bisphosphate production at the cleavage furrow

Watanabe, H., Okahara, K., Naito-Matsui, Y., Abe, M., Go, S., Inokuchi, J., Okazaki, T., Kobayashi, T., Kozutsumi, Y., Oka, S. & Takematsu, H., 01-07-2016, In: Molecular Biology of the Cell. 27, 13, p. 2037-2050 14 p.

研究成果: Article › 査読

Open Access

6 被引用数 (Scopus)

The signaling pathways underlying starvation-induced upregulation of α-mannosidase Ams1 in Saccharomyces cerevisiae

Umekawa, M., Ujihara, M., Makishima, K., Yamamoto, S., Takematsu, H. & Wakayama, M., 01-06-2016, In: Biochimica et Biophysica Acta - General Subjects. 1860, 6, p. 1192-1201 10 p.

研究成果: Article › 査読

5 被引用数 (Scopus)

2015

A sulfated glycosaminoglycan linkage region is a novel type of human natural killer-1 (HNK-1) epitope expressed on aggrecan in perineuronal nets

Yabuno, K., Morise, J., Kizuka, Y., Hashii, N., Kawasaki, N., Takahashi, S., Miyata, S., Izumikawa, T., Kitagawa, H., Takematsu, H. & Oka, S., 01-12-2015, In: PloS one. 10, 12, e0144560.

研究成果: Article › 査読

Open Access

16 被引用数 (Scopus)

Ectopic clustering of Cajal-Retzius and subplate cells is an initial pathological feature in Pomgnt2-knockout mice, a model of dystroglycanopathy

Nakagawa, N., Yagi, H., Kato, K., Takematsu, H. & Oka, S., 10-06-2015, In: Scientific reports. 5, 11163.

研究成果: Article › 査読

Open Access

13 被引用数 (Scopus)

Enhancement of neutrophil autophagy by an IVIG preparation against multidrug-resistant bacteria as well as drug-sensitive strains

Itoh, H., Matsuo, H., Kitamura, N., Yamamoto, S., Higuchi, T., Takematsu, H., Kamikubo, Y., Kondo, T., Yamashita, K., Sasada, M., Takaori-Kondo, A. & Adachi, S., 01-07-2015, In: Journal of Leukocyte Biology. 98, 1, p. 107-117 11 p.

研究成果: Article › 査読

Open Access

22 被引用数 (Scopus)

Major glycan structure underlying expression of the Lewis X epitope in the developing brain is O-mannose-linked glycans on phosphacan/RPTPβ

Yaji, S., Manya, H., Nakagawa, N., Takematsu, H., Endo, T., Kannagi, R., Yoshihara, T., Asano, M. & Oka, S., 01-04-2015, In: Glycobiology. 25, 4, p. 376-385 10 p.

研究成果: Article › 査読

Open Access

19 被引用数 (Scopus)

Role of site-specific N-glycans expressed on GluA2 in the regulation of cell surface expression of AMPA-type glutamate receptors

Takeuchi, Y., Morise, J., Morita, I., Takematsu, H. & Oka, S., 13-08-2015, In: PloS one. 10, 8, e0135644.

研究成果: Article › 査読

Open Access

18 被引用数 (Scopus)

2014

Fpk1/2 kinases regulate cellular sphingoid long-chain base abundance and alter cellular resistance to LCB elevation or depletion

Yamane-Sando, Y., Shimobayashi, E., Shimobayashi, M., Kozutsumi, Y., Oka, S. & Takematsu, H., 04-2014, In: MicrobiologyOpen. 3, 2, p. 196-212 17 p.

研究成果: Article › 査読

Open Access

10 被引用数 (Scopus)

Functional evaluation of activation-dependent alterations in the sialoglycan composition of T cells

Naito-Matsui, Y., Takada, S., Kano, Y., Iyoda, T., Sugai, M., Shimizu, A., Inaba, K., Nitschke, L., Tsubata, T., Oka, S., Kozutsumi, Y. & Takematsu, H., 17-01-2014, In: Journal of Biological Chemistry. 289, 3, p. 1564-1579 16 p.

研究成果: Article › 査読

Open Access

22 被引用数 (Scopus)

Structural and biochemical characterization of O-mannose-linked human natural killer-1 glycan expressed on phosphacan in developing mouse brains

Morise, J., Kizuka, Y., Yabuno, K., Tonoyama, Y., Hashii, N., Kawasaki, N., Manya, H., Miyagoe-Suzuki, Y., Takeda, SI., Endo, T., Maeda, N., Takematsu, H. & Oka, S., 03-2014, In: Glycobiology. 24, 3, p. 314-324 11 p.

研究成果: Article › 査読

Open Access

30 被引用数 (Scopus)

2013

HNK-1 sulfotransferase-dependent sulfation regulating laminin-binding glycans occurs in the post-phosphoryl moiety on α-dystroglycan

Nakagawa, N., Takematsu, H. & Oka, S., 09-2013, In: Glycobiology. 23, 9, p. 1066-1074 9 p.

研究成果: Article › 査読

Open Access

14 被引用数 (Scopus)

2012

CD22 serves as a receptor for soluble IgM

Adachi, T., Harumiya, S., Takematsu, H., Kozutsumi, Y., Wabl, M., Fujimoto, M. & Tedder, T. F., 01-2012, In: European Journal of Immunology. 42, 1, p. 241-247 7 p.

研究成果: Article › 査読

32 被引用数 (Scopus)

Orm protein phosphoregulation mediates transient sphingolipid biosynthesis response to heat stress via the Pkh-Ypk and Cdc55-PP2A pathways

Sun, Y., Miao, Y., Yamane, Y., Zhang, C., Shokat, K. M., Takematsu, H., Kozutsumi, Y. & Drubin, D. G., 15-06-2012, In: Molecular Biology of the Cell. 23, 12, p. 2388-2398 11 p.

研究成果: Article › 査読

Open Access

100 被引用数 (Scopus)

2011

Analysis of multiple compound-protein interactions reveals novel bioactive molecules

Yabuuchi, H., Niijima, S., Takematsu, H., Ida, T., Hirokawa, T., Hara, T., Ogawa, T., Minowa, Y., Tsujimoto, G. & Okuno, Y., 2011, In: Molecular Systems Biology. 7, 472.

研究成果: Article › 査読

Open Access

112 被引用数 (Scopus)

CD22-Antagonists with nanomolar potency: The synergistic effect of hydrophobic groups at C-2 and C-9 of sialic acid scaffold

Abdu-Allah, H. H. M., Watanabe, K., Completo, G. C., Sadagopan, M., Hayashizaki, K., Takaku, C., Tamanaka, T., Takematsu, H., Kozutsumi, Y., Paulson, J. C., Tsubata, T., Ando, H., Ishida, H. & Kiso, M., 15-03-2011, In: Bioorganic and Medicinal Chemistry. 19, 6, p. 1966-1971 6 p.

研究成果: Article › 査読

27 被引用数 (Scopus)

Quantitative transcriptomic profiling of branching in a glycosphingolipid biosynthetic pathway

Takematsu, H., Yamamoto, H., Naito-Matsui, Y., Fujinawa, R., Tanaka, K., Okuno, Y., Tanaka, Y., Kyogashima, M., Kannagi, R. & Kozutsumi, Y., 05-08-2011, In: Journal of Biological Chemistry. 286, 31, p. 27214-27224 11 p.

研究成果: Article › 査読

Open Access

11 被引用数 (Scopus)

Sphingosylphosphorylcholine and lysosulfatide have inverse regulatory functions in monocytic cell differentiation into macrophages

Yamamoto, H., Naito, Y., Okano, M., Kanazawa, T., Takematsu, H. & Kozutsumi, Y., 01-02-2011, In: Archives of Biochemistry and Biophysics. 506, 1, p. 83-91 9 p.

研究成果: Article › 査読

8 被引用数 (Scopus)

2010

Binding to gangliosides containing N-acetylneuraminic acid is sufficient to mediate the immunomodulatory properties of the nontoxic mucosal adjuvant LT-IIb(T13I)

Nawar, H. F., Berenson, C. S., Hajishengallis, G., Takematsu, H., Mandell, L., Clare, R. L. & Connell, T. D., 06-2010, In: Clinical and Vaccine Immunology. 17, 6, p. 969-978 10 p.

研究成果: Article › 査読

Open Access

11 被引用数 (Scopus)

Identification of Ypk1 as a novel selective substrate for nitrogen starvation-triggered proteolysis requiring autophagy system and endosomal sorting complex required for transport (ESCRT) machinery components

Shimobayashi, M., Takematsu, H., Eiho, K., Yamane, Y. & Kozutsumi, Y., 19-11-2010, In: Journal of Biological Chemistry. 285, 47, p. 36984-36994 11 p.

研究成果: Article › 査読

Open Access

12 被引用数 (Scopus)

Immunological property of antibodies against N-glycolylneuraminic acid epitopes in cytidine monophospho - N-acetylneuraminic acid hydroxylase-deficient mice

Tahara, H., Ide, K., Basnet, N. B., Tanaka, Y., Matsuda, H., Takematsu, H., Kozutsumi, Y. & Ohdan, H., 15-03-2010, In: Journal of Immunology. 184, 6, p. 3269-3275 7 p.

研究成果: Article › 査読

Open Access

36 被引用数 (Scopus)

Regulation and function of sialic acid modifications in B lymphocytes

Takematsu, H., 01-12-2010, In: Seikagaku. 82, 8, p. 735-740 6 p.

研究成果: Article › 査読

1 被引用数 (Scopus)

Synthesis and binding analysis of unique AG2 pentasaccharide to human Siglec-2 using NMR techniques

Hanashima, S., Sato, K. I., Naito, Y., Takematsu, H., Kozutsumi, Y., Ito, Y. & Yamaguchi, Y., 01-06-2010, In: Bioorganic and Medicinal Chemistry. 18, 11, p. 3720-3725 6 p.

研究成果: Article › 査読

13 被引用数 (Scopus)

2009

B cell antigen receptor signal strength and peripheral B cell development are regulated by a 9-O-acetyl sialic acid esterase

Cariappa, A., Takematsu, H., Liu, H., Diaz, S., Haider, K., Boboila, C., Kalloo, G., Connole, M., Shi, H. N., Varki, N., Varki, A. & Pillai, S., 16-01-2009, In: Journal of Experimental Medicine. 206, 1, p. 125-138 14 p.

研究成果: Article › 査読

Open Access

97 被引用数 (Scopus)

Glycosphingolipids are not pivotal receptors for Subtilase cytotoxin in vivo: Sensitivity analysis with glycosylation-defective mutant mice

Kondo, Y., Tokuda, N., Fan, X., Yamashita, T., Honke, K., Takematsu, H., Togayachi, A., Ohta, M., Kotzusumi, Y., Narimatsu, H., Tajima, O., Furukaw, K. & Furukawa, K., 09-01-2009, In: Biochemical and Biophysical Research Communications. 378, 2, p. 179-181 3 p.

研究成果: Article › 査読

12 被引用数 (Scopus)

Potent small molecule mouse CD22-inhibitors: Exploring the interaction of the residue at C-2 of sialic acid scaffold

Abdu-Allah, H. H. M., Watanabe, K., Hayashizaki, K., Takaku, C., Tamanaka, T., Takematsu, H., Kozutsumi, Y., Tsubata, T., Ishida, H. & Kiso, M., 01-10-2009, In: Bioorganic and Medicinal Chemistry Letters. 19, 19, p. 5573-5575 3 p.

研究成果: Article › 査読

15 被引用数 (Scopus)

Synthesis of biotinylated sialoside to probe CD22-ligand interactions

Abdu-Allah, H. H. M., Watanabe, K., Hayashizaki, K., Iwayama, Y., Takematsu, H., Kozutsumi, Y., Tsubata, T., Ishida, H. & Kiso, M., 05-08-2009, In: Tetrahedron Letters. 50, 31, p. 4488-4491 4 p.

研究成果: Article › 査読

10 被引用数 (Scopus)

2008

Establishment of the culture model system that reflects the process of terminal differentiation of connective tissue-type mast cells

Takano, H., Nakazawa, S., Okuno, Y., Shirata, N., Tsuchiya, S., Kainoh, T., Takamatsu, S., Furuta, K., Taketomi, Y., Naito, Y., Takematsu, H., Kozutsumi, Y., Tsujimoto, G., Murakami, M., Kudo, I., Ichikawa, A., Nakayama, K., Sugimoto, Y. & Tanaka, S., 30-04-2008, In: FEBS Letters. 582, 10, p. 1444-1450 7 p.

研究成果: Article › 査読

Open Access

34 被引用数 (Scopus)

Wheat germ agglutinin stains dispersed post-golgi vesicles after treatment with the cytokinesis inhibitor psychosine

Kanazawa, T., Takematsu, H., Yamamoto, A., Yamamoto, H. & Kozutsumi, Y., 01-05-2008, In: Journal of Cellular Physiology. 215, 2, p. 517-525 9 p.

研究成果: Article › 査読

13 被引用数 (Scopus)

2007

Correlation index-based responsible-enzyme gene screening (CIRES), a novel DNA microarray-based method for enzyme gene involved in glycan biosynthesis

Yamamoto, H., Takematsu, H., Fujinawa, R., Naito, Y., Okuno, Y., Tsujimoto, G., Suzuki, A. & Kozutsumi, Y., 28-11-2007, In: PloS one. 2, 11, e1232.

研究成果: Article › 査読

Open Access

13 被引用数 (Scopus)

Germinal center marker GL7 probes activation-dependent repression of N-glycolylneuraminic acid, a sialic acid species involved in the negative modulation of B-cell activation

Naito, Y., Takematsu, H., Koyama, S., Miyake, S., Yamamoto, H., Fujinawa, R., Sugai, M., Okuno, Y., Tsujimoto, G., Yamaji, T., Hashimoto, Y., Itohara, S., Kawasaki, T., Suzuki, A. & Kozutsumi, Y., 04-2007, In: Molecular and Cellular Biology. 27, 8, p. 3008-3022 15 p.

研究成果: Article › 査読

Open Access

139 被引用数 (Scopus)

Human B-lymphocytes express α2-6-sialylated 6-sulfo-N- acetyllactosamine serving as a preferred ligand for CD22/siglec-2

Kimura, N., Ohmori, K., Miyazaki, K., Izawa, M., Matsuzaki, Y., Yasuda, Y., Takematsu, H., Kozutsumi, Y., Moriyama, A. & Kannagi, R., 02-11-2007, In: Journal of Biological Chemistry. 282, 44, p. 32200-32207 8 p.

研究成果: Article › 査読

Open Access

60 被引用数 (Scopus)

竹松 弘

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竹松弘