年別の研究成果
年別の研究成果
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2022
Andrographolide, isolated from Andrographis paniculata, induces apoptosis in monocytic leukemia and multiple myeloma cells via augmentation of reactive oxygen species production
Akiyama, H., Doi, H., Matsui, T., Dijkstra, J. M., Ogasawara, A., Higashimoto, Y., Imamura, S., Ohye, T., Takematsu, H. & Katsuda, I., 2022, In: F1000Research. 10, 542.研究成果: Article › 査読
Open Access -
Target enrichment long-read sequencing with adaptive sampling can determine the structure of the small supernumerary marker chromosomes
Mariya, T., Kato, T., Sugimoto, T., Miyai, S., Inagaki, H., Ohye, T., Sugihara, E., Muramatsu, Y., Mizuno, S. & Kurahashi, H., 06-2022, In: Journal of Human Genetics. 67, 6, p. 363-368 6 p.研究成果: Article › 査読
4 被引用数 (Scopus) -
2021
Andrographolide, isolated from Andrographis paniculata, induces apoptosis in monocytic leukemia and multiple myeloma cells via augmentation of reactive oxygen species production
Doi, H., Matsui, T., Dijkstra, J. M., Ogasawara, A., Higashimoto, Y., Imamura, S., Ohye, T., Takematsu, H., Katsuda, I. & Akiyama, H., 2021, In: F1000Research. 10, p. 542 1 p.研究成果: Article › 査読
Open Access1 被引用数 (Scopus) -
Coinfection with Human Herpesvirus (HHV)-6B in Immunocompetent, Healthy Individuals with Chromosomally Integrated HHV-6A
Miura, H., Ohye, T., Kozawa, K., Hattori, F., Kawamura, Y., Ihira, M., Kurahashi, H. & Yoshikawa, T., 01-02-2021, In: Journal of the Pediatric Infectious Diseases Society. 10, 2, p. 175-178 4 p.研究成果: Article › 査読
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Inherited Chromosomally Integrated Human Herpesvirus 6 Is a Risk Factor for Spontaneous Abortion
Miura, H., Kawamura, Y., Ohye, T., Hattori, F., Kozawa, K., Ihira, M., Yatsuya, H., Nishizawa, H., Kurahashi, H. & Yoshikawa, T., 15-05-2021, In: Journal of Infectious Diseases. 223, 10, p. 1717-1723 7 p.研究成果: Article › 査読
10 被引用数 (Scopus) -
Tyrosine hydroxylase conditional KO mice reveal peripheral tissue-dependent differences in dopamine biosynthetic pathways
Miyajima, K., Kawamoto, C., Hara, S., Mori-Kojima, M., Ohye, T., Sumi-Ichinose, C., Saito, N., asaoka, T., Metzger, D. & Ichinose, H., 01-01-2021, In: Journal of Biological Chemistry. 296, 100544.研究成果: Article › 査読
Open Access2 被引用数 (Scopus) -
2020
Inherited chromosomally integrated human herpesvirus-6 in a patient with XIAP deficiency
Inoue, K., Miura, H., Hoshino, A., Kamiya, T., Tanita, K., Ohye, T., Park, M. J., Yanagimachi, M., Takagi, M., Imai, K., Morio, T., Yoshikawa, T. & Kanegane, H., 01-10-2020, In: Transplant Infectious Disease. 22, 5, e13331.研究成果: Article › 査読
5 被引用数 (Scopus) -
2018
Chromosomally integrated human herpesvirus 6 in the Japanese population
Miura, H., Kawamura, Y., Hattori, F., Kozawa, K., Ihira, M., Ohye, T., Kurahashi, H. & Yoshikawa, T., 10-2018, In: Journal of Medical Virology. 90, 10, p. 1636-1642 7 p.研究成果: Article › 査読
14 被引用数 (Scopus) -
2017
Analysis of the origin of inherited chromosomally integrated human herpesvirus 6 in the Japanese population
Kawamura, Y., Ohye, T., Miura, H., Ihira, M., Kato, Y., Kurahashi, H. & Yoshikawa, T., 07-2017, In: Journal of General Virology. 98, 7, p. 1823-1830 8 p., 000834.研究成果: Article › 査読
10 被引用数 (Scopus) -
Transmission of chromosomally integrated human herpesvirus 6 via cord blood transplantation
Yamada, Y., Osumi, T., Imadome, K. I., Takahashi, E., Ohye, T., Yoshikawa, T., Tomizawa, D., Kato, M. & Matsumoto, K., 01-02-2017, In: Transplant Infectious Disease. 19, 1, e12636.研究成果: Article › 査読
6 被引用数 (Scopus) -
2016
A simple cytogenetic method to detect chromosomally integrated human herpesvirus-6
Ohye, T., Kawamura, Y., Inagaki, H., Yoshikawa, A., Ihira, M., Yoshikawa, T. & Kurahashi, H., 01-02-2016, In: Journal of Virological Methods. 228, p. 74-78 5 p.研究成果: Article › 査読
9 被引用数 (Scopus) -
2015
Identification of novel FATP4 mutations in a Japanese patient with ichthyosis prematurity syndrome
Tsuge, I., Morishita, M., Kato, T., Tsutsumi, M., Inagaki, H., Mori, Y., Yamawaki, K., Inuo, C., Ieda, K., Ohye, T., Hayakawa, A. & Kurahashi, H., 12-02-2015, In: Human Genome Variation. 2, 15003.研究成果: Article › 査読
Open Access6 被引用数 (Scopus) -
Intragenic duplication in the PHKD1 gene in autosomal recessive polycystic kidney disease
Miyazaki, J., Ito, M., Nishizawa, H., Kato, T., Minami, Y., Inagaki, H., Ohye, T., Miyata, M., Boda, H., Kiriyama, Y., Kuroda, M., Sekiya, T., Kurahashi, H. & Fujii, T., 26-10-2015, In: BMC Medical Genetics. 16, 1, 98.研究成果: Article › 査読
Open Access3 被引用数 (Scopus) -
Virological analysis of inherited chromosomally integrated human herpesvirus-6 in three hematopoietic stem cell transplant patients
Miura, H., Kawamura, Y., Kudo, K., Ihira, M., Ohye, T., Kurahashi, H., Kawashima, N., Miyamura, K., Yoshida, N., Kato, K., Takahashi, Y., Kojima, S. & Yoshikawa, T., 10-2015, In: Transplant Infectious Disease. 17, 5, p. 728-731 4 p.研究成果: Article › 査読
12 被引用数 (Scopus) -
2014
[Positive and negative aspects of genetic testing for familial cancer].
Oe, T. & Kurahashi, H., 01-01-2014, In: Unknown Journal. 115, 1, p. 34-38 5 p.研究成果: Article › 査読
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Acute eosinophilic pneumonia occurring in a dedicator of cytokinesis 8 (DOCK8) deficient patient
Tsuge, I., Ito, K., Ohye, T., Kando, N., Kondo, Y., Nakajima, Y., Inuo, C., Kurahashi, H. & Urisu, A., 03-2014, In: Pediatric Pulmonology. 49, 3, p. E52-E55研究成果: Article › 査読
6 被引用数 (Scopus) -
Age-related decrease of meiotic cohesins in human oocytes
Tsutsumi, M., Fujiwara, R., Nishizawa, H., Ito, M., Kogo, H., Inagaki, H., Ohye, T., Kato, T., Fujii, T. & Kurahashi, H., 07-05-2014, In: PloS one. 9, 5, e96710.研究成果: Article › 査読
Open Access98 被引用数 (Scopus) -
A MEN2A family with two asymptomatic carriers affected by unilateral renal agenesis
Hibi, Y., Ohye, T., Ogawa, K., Shimizu, Y., Shibata, M., Kagawa, C., Mizuno, Y., Kurahashi, H. & Iwase, K., 2014, In: endocrine journal. 61, 1, p. 19-23 5 p.研究成果: Article › 査読
9 被引用数 (Scopus) -
An immunocompetent child with chromosomally integrated human herpesvirus 6B accidentally identified during the care of Mycoplasma pneumoniae infection
Oikawa, J., Tanaka, J., Yoshikawa, T., Morita, Y., Hishiki, H., Ishiwada, N., Ohye, T., Kurahashi, H. & Kohno, Y., 01-2014, In: Journal of Infection and Chemotherapy. 20, 1, p. 65-67 3 p.研究成果: Article › 査読
4 被引用数 (Scopus) -
Dual roles for the telomeric repeats in chromosomally integrated human herpesvirus-6
Ohye, T., Inagaki, H., Ihira, M., Higashimoto, Y., Kato, K., Oikawa, J., Yagasaki, H., Niizuma, T., Takahashi, Y., Kojima, S., Yoshikawa, T. & Kurahashi, H., 02-04-2014, In: Scientific reports. 4, 4559.研究成果: Article › 査読
Open Access21 被引用数 (Scopus) -
Molecular and virological evidence of viral activation from chromosomally integrated human herpesvirus 6A in a patient with X-linked severe combined immunodeficiency
Endo, A., Watanabe, K., Ohye, T., Suzuki, K., Matsubara, T., Shimizu, N., Kurahashi, H., Yoshikawa, T., Katano, H., Inoue, N., Imai, K., Takagi, M., Morio, T. & Mizutani, S., 15-08-2014, In: Clinical Infectious Diseases. 59, 4, p. 545-548 4 p.研究成果: Article › 査読
Open Access102 被引用数 (Scopus) -
Pheochromocytoma as the first manifestation of MEN2A with RET mutation S891A: report of a case
Hibi, Y., Ohye, T., Ogawa, K., Shimizu, Y., Shibata, M., Kagawa, C., Mizuno, Y., Uchino, S., Kosugi, S., Kurahashi, H. & Iwase, K., 11-10-2014, In: Surgery Today. 44, 11, p. 2195-2200 6 p.研究成果: Article › 査読
Open Access2 被引用数 (Scopus) -
Signature of backward replication slippage at the copy number variation junction
Ohye, T., Inagaki, H., Ozaki, M., Ikeda, T. & Kurahashi, H., 05-2014, In: Journal of Human Genetics. 59, 5, p. 247-250 4 p.研究成果: Article › 査読
3 被引用数 (Scopus) -
2013
Definition and refinement of the 7q36.3 duplication region associated with schizophrenia
Aleksic, B., Kushima, I., Ohye, T., Ikeda, M., Kunimoto, S., Nakamura, Y., Yoshimi, A., Koide, T., Iritani, S., Kurahashi, H., Iwata, N. & Ozaki, N., 2013, In: Scientific reports. 3, 2587.研究成果: Article › 査読
Open Access5 被引用数 (Scopus) -
Identification of an enhancer region for immune activation in the human GTP cyclohydrolase i gene
Liang, Y., Inagaki, H., Hao, Q., Sakamoto, M., Ohye, T., Suzuki, T. & Ichinose, H., 06-12-2013, In: Biochemical and Biophysical Research Communications. 442, 1-2, p. 72-78 7 p.研究成果: Article › 査読
2 被引用数 (Scopus) -
Two sequential cleavage reactions on cruciform DNA structures cause palindrome-mediated chromosomal translocations
Inagaki, H., Ohye, T., Kogo, H., Tsutsumi, M., Kato, T., Tong, M., Emanuel, B. S. & Kurahashi, H., 2013, In: Nature communications. 4, 1592.研究成果: Article › 査読
Open Access35 被引用数 (Scopus) -
2012
Failure of homologous synapsis and sex-specific reproduction problems
Kurahashi, H., Kogo, H., Tsutsumi, M., Inagaki, H. & Ohye, T., 2012, In: Frontiers in Genetics. 3, JUN, Article 112.研究成果: Article › 査読
27 被引用数 (Scopus) -
HORMAD1-dependent checkpoint/surveillance mechanism eliminates asynaptic oocytes
Kogo, H., Tsutsumi, M., Ohye, T., Inagaki, H., Abe, T. & Kurahashi, H., 06-2012, In: Genes to Cells. 17, 6, p. 439-454 16 p.研究成果: Article › 査読
46 被引用数 (Scopus) -
HORMAD2 is essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity
Kogo, H., Tsutsumi, M., Inagaki, H., Ohye, T., Kiyonari, H. & Kurahashi, H., 11-2012, In: Genes to Cells. 17, 11, p. 897-912 16 p.研究成果: Article › 査読
42 被引用数 (Scopus) -
Molecular basis of maternal age-related increase in oocyte aneuploidy
Kurahashi, H., Tsutsumi, M., Nishiyama, S., Kogo, H., Inagaki, H. & Ohye, T., 03-2012, In: Congenital anomalies. 52, 1, p. 8-15 8 p.研究成果: Article › 査読
31 被引用数 (Scopus) -
Screening of genes involved in chromosome segregation during meiosis I: In vitro gene transfer to mouse fetal oocytes
Tsutsumi, M., Kowa-Sugiyama, H., Bolor, H., Kogo, H., Inagaki, H., Ohye, T., Yamada, K., Taniguchi-Ikeda, M., Toda, T. & Kurahashi, H., 08-2012, In: Journal of Human Genetics. 57, 8, p. 515-522 8 p.研究成果: Article › 査読
4 被引用数 (Scopus) -
2011
Characterization of a novel mouse gene encoding an SYCP3-like protein that relocalizes from the XY body to the nucleolus during prophase of male meiosis I
Tsutsumi, M., Kogo, H., Kowa-Sugiyama, H., Inagaki, H., Ohye, T. & Kurahashi, H., 01-07-2011, In: Biology of Reproduction. 85, 1, p. 165-171 7 p.研究成果: Article › 査読
15 被引用数 (Scopus) -
DNA secondary structure is influenced by genetic variation and alters susceptibility to de novo translocation
Kato, T., Inagaki, H., Tong, M., Kogo, H., Ohye, T., Yamada, K., Tsutsumi, M., Emanuel, B. S. & Kurahashi, H., 2011, In: Molecular Cytogenetics. 4, 1, 18.研究成果: Article › 査読
Open Access7 被引用数 (Scopus) -
2010
Paternal origin of the de novo constitutional t(11;22)(q23;q11)
Ohye, T., Inagaki, H., Kogo, H., Tsutsumi, M., Kato, T., Tong, M., MacVille, M. V. E., Medne, L., Zackai, E. H., Emanuel, B. S. & Kurahashi, H., 07-2010, In: European Journal of Human Genetics. 18, 7, p. 783-787 5 p.研究成果: Article › 査読
Open Access27 被引用数 (Scopus) -
Polymorphisms of the 22q11.2 breakpoint region influence the frequency of de novo constitutional t(11;22)s in sperm
Tong, M., Kato, T., Yamada, K., Inagaki, H., Kogo, H., Ohye, T., Tsutsumi, M., Wang, J., Emanuel, B. S. & Kurahashi, H., 13-04-2010, In: Human molecular genetics. 19, 13, p. 2630-2637 8 p., ddq150.研究成果: Article › 査読
Open Access16 被引用数 (Scopus) -
Screening of genes involved in chromosome segregation during meiosis I: Toward the identification of genes responsible for infertility in humans
Kogo, H., Kowa-Sugiyama, H., Yamada, K., Bolor, H., Tsutsumi, M., Ohye, T., Inagaki, H., Taniguchi, M., Toda, T. & Kurahashi, H., 05-2010, In: Journal of Human Genetics. 55, 5, p. 293-299 7 p.研究成果: Article › 査読
18 被引用数 (Scopus) -
2009
Chromosomal instability mediated by non-B DNA: Cruciform conformation and not DNA sequence is responsible for recurrent translocation in humans
Inagaki, H., Ohye, T., Kogo, H., Kato, T., Bolor, H., Taniguchi, M., Shaikh, T. H., Emanuel, B. S. & Kurahashi, H., 02-2009, In: Genome Research. 19, 2, p. 191-198 8 p.研究成果: Article › 査読
Open Access66 被引用数 (Scopus) -
Impaired DNA replication prompts deletions within palindromic sequences, but does not induce translocations in human cells
Kurahashi, H., Inagaki, H., Kato, T., Hosoba, E., Kogo, H., Ohye, T., Tsutsumi, M., Bolor, H., Tong, M. & Emanuel, B. S., 2009, In: Human molecular genetics. 18, 18, p. 3397-3406 10 p.研究成果: Article › 査読
Open Access14 被引用数 (Scopus) -
Mutations of the SYCP3 Gene in Women with Recurrent Pregnancy Loss
Bolor, H., Mori, T., Nishiyama, S., Ito, Y., Hosoba, E., Inagaki, H., Kogo, H., Ohye, T., Tsutsumi, M., Kato, T., Tong, M., Nishizawa, H., Pryor-Koishi, K., Kitaoka, E., Sawada, T., Nishiyama, Y., Udagawa, Y. & Kurahashi, H., 09-01-2009, In: American Journal of Human Genetics. 84, 1, p. 14-20 7 p.研究成果: Article › 査読
Open Access77 被引用数 (Scopus) -
2008
Two different forms of palindrome resolution in the human genome: Deletion or translocation
Kato, T., Inagaki, H., Kogo, H., Ohye, T., Yamada, K., Emanuel, B. S. & Kurahashi, H., 15-04-2008, In: Human molecular genetics. 17, 8, p. 1184-1191 8 p.研究成果: Article › 査読
17 被引用数 (Scopus) -
2007
Age has no effect on de novo constitutional t(11;22) translocation frequency in sperm
Kato, T., Yamada, K., Inagaki, H., Kogo, H., Ohye, T., Emanuel, B. S. & Kurahashi, H., 11-2007, In: Fertility and Sterility. 88, 5, p. 1446-1448 3 p.研究成果: Article › 査読
Open Access16 被引用数 (Scopus) -
Cruciform extrusion propensity of human translocation-mediating palindromic AT-rich repeats
Kogo, H., Inagaki, H., Ohye, T., Kato, T., Emanuel, B. S. & Kurahashi, H., 02-2007, In: Nucleic acids research. 35, 4, p. 1198-1208 11 p.研究成果: Article › 査読
Open Access29 被引用数 (Scopus) -
Molecular cloning of a translocation breakpoint hotspot in 22q11
Kurahashi, H., Inagaki, H., Hosoba, E., Kato, T., Ohye, T., Kogo, H. & Emanuel, B. S., 04-2007, In: Genome Research. 17, 4, p. 461-469 9 p.研究成果: Article › 査読
40 被引用数 (Scopus) -
2006
Genetic variation affects de novo translocation frequency
Kato, T., Inagaki, H., Yamada, K., Kogo, H., Ohye, T., Kowa, H., Nagaoka, K., Taniguchi, M., Emanuel, B. S. & Kurahashi, H., 17-02-2006, In: Science. 311, 5763, p. 971 1 p.研究成果: Article › 査読
60 被引用数 (Scopus) -
Palindrome-mediated chromosomal translocations in humans
Kurahashi, H., Inagaki, H., Ohye, T., Kogo, H., Kato, T. & Emanuel, B. S., 08-09-2006, In: DNA Repair. 5, 9-10, p. 1136-1145 10 p.研究成果: Article › 査読
79 被引用数 (Scopus) -
2005
Palindromic AT-rich repeat in the NF1 gene is hypervariable in humans and evolutionarily conserved in primates
Inagaki, H., Ohye, T., Kogo, H., Yamada, K., Kowa, H., Shaikh, T. H., Emanuel, B. S. & Kurahashi, H., 10-2005, In: Human Mutation. 26, 4, p. 332-342 11 p.研究成果: Article › 査読
33 被引用数 (Scopus) -
2004
Cruciform DNA structure underlies the etiology for palindrome-mediated human chromosomal translocations
Kurahashi, H., Inagaki, H., Yamada, K., Ohye, T., Taniguchi, M., Emanuel, B. S. & Toda, T., 20-08-2004, In: Journal of Biological Chemistry. 279, 34, p. 35377-35383 7 p.研究成果: Article › 査読
Open Access97 被引用数 (Scopus) -
2003
Biopterin metabolism in patients with malignant syndrome
Ichinose, H., Ohye, T., Shinotoh, H., Arai, K., Yamazaki, S., Mizuta, E., Kuno, S. & Nagatsu, T., 04-2003, In: Parkinsonism and Related Disorders. 9, SUPPL. 1, p. 11-14 4 p.研究成果: Article › 査読
1 被引用数 (Scopus) -
2002
Localization of sepiapterin reductase in the human brain
Ikemoto, K., Suzuki, T., Ichinose, H., Ohye, T., Nishimura, A., Nishi, K., Nagatsu, I. & Nagatsu, T., 08-11-2002, In: Brain Research. 954, 2, p. 237-246 10 p.研究成果: Article › 査読
8 被引用数 (Scopus) -
2001
A new splicing variant for human tyrosine hydroxylase in the adrenal medulla
Ohye, T., Ichinose, H., Yoshizawa, T., Kanazawa, I. & Nagatsu, T., 26-10-2001, In: Neuroscience Letters. 312, 3, p. 157-160 4 p.研究成果: Article › 査読
15 被引用数 (Scopus)