坪井 良樹

研究成果

年別の研究成果 2018 2022 2022

• 17 Article
• 1 Comment/debate
• 1 Review article

年別の研究成果

年別の研究成果

検索結果

• 2022

  Association between serum carotenoids and premature mortality in a population-based case-control study

  Fujii, R., Suzuki, K., Yamada, H., Kawado, M., Hashimoto, S., Tsuboi, Y., Wakai, K., Iso, H., Watanabe, Y., Fujino, Y. & Tamakoshi, A., 2022, In: Nagoya journal of medical science. 84, 3, p. 607-620 14 p.

  研究成果: Article › 査読

  • Cryptoxanthins 100%
  • Carotenoids 97%
  • Premature Mortality 94%
  • Case-Control Studies 65%
  • Provitamins 64%

• Association between the Extent of Peripheral Blood DNA Methylation of HIF3A and Accumulation of Adiposity in community-dwelling Women: The Yakumo Study

  Mizuno, G., Yamada, H., Munetsuna, E., Yamazaki, M., Ando, Y., Fujii, R., Tsuboi, Y., Teshigawara, A., Kageyama, I., Osakabe, K., Sugimoto, K., Ishikawa, H., Ichino, N., Ohta, Y., Ohashi, K., Hashimoto, S. & Suzuki, K., 2022, In: Endocrine Research. 47, 3-4, p. 130-137 8 p.

  研究成果: Article › 査読

  • Adiposity 100%
  • Independent Living 98%
  • DNA Methylation 94%
  • Body Mass Index 34%
  • Intra-Abdominal Fat 17%

• Association of drinking behaviors with TXNIP DNA methylation levels in leukocytes among the general Japanese population

  Maeda, K., Yamada, H., Munetsuna, E., Fujii, R., Yamazaki, M., Ando, Y., Mizuno, G., Ishikawa, H., Ohashi, K., Tsuboi, Y., Hattori, Y., Ishihara, Y., Hashimoto, S., Hamajima, N. & Suzuki, K., 2022, In: American Journal of Drug and Alcohol Abuse. 48, 3, p. 302-310 9 p.

  研究成果: Article › 査読

  • Drinking Behavior 100%
  • Thioredoxins 97%
  • DNA Methylation 76%
  • Leukocytes 61%
  • alcohol 59%
  1 被引用数 (Scopus)

• Associations of Genome-Wide Polygenic Risk Score and Risk Factors with Hypertension in a Japanese Population

  Fujii, R., Hishida, A., Nakatochi, M., Tsuboi, Y., Suzuki, K., Kondo, T., Ikezaki, H., Hara, M., Okada, R., Tamura, T., Shimoshikiryo, I., Suzuki, S., Koyama, T., Kuriki, K., Takashima, N., Arisawa, K., Momozawa, Y., Kubo, M., Takeuchi, K. & Wakai, K., 01-08-2022, In: Circulation. Genomic and precision medicine. 15, 4, p. E003612

  研究成果: Article › 査読

  • Genome 100%
  • Hypertension 95%
  • Blood Pressure 66%
  • Population 57%
  • Japan 17%

• Increased brain-derived neurotrophic factor in the serum of persons with nonalcoholic fatty liver disease

  Hattori, Y., Yamada, H., Munetsuna, E., Ando, Y., Mizuno, G., Fujii, R., Tsuboi, Y., Ichino, N., Osakabe, K., Sugimoto, K., Ishikawa, H., Ohashi, K. & Suzuki, K., 2022, In: endocrine journal. 69, 8, p. 999-1006 8 p.

  研究成果: Article › 査読

  Open Access

  • Non-alcoholic Fatty Liver Disease 100%
  • Brain-Derived Neurotrophic Factor 98%
  • Serum 42%
  • Fatty Liver 11%
  • Liver 10%
  1 被引用数 (Scopus)

• Increased risk of cancer mortality by smoking-induced aryl hydrocarbon receptor repressor DNA hypomethylation in Japanese population: A long-term cohort study

  Tsuboi, Y., Yamada, H., Munetsuna, E., Fujii, R., Yamazaki, M., Ando, Y., Mizuno, G., Hattori, Y., Ishikawa, H., Ohashi, K., Hashimoto, S., Hamajima, N. & Suzuki, K., 06-2022, In: Cancer Epidemiology. 78, 102162.

  研究成果: Article › 査読

  Open Access

  • Aryl Hydrocarbon Receptors 100%
  • Smoking 56%
  • Cohort Studies 53%
  • DNA 43%
  • Mortality 39%

• Intake of vegetables and fruits rich in provitamin A is positively associated with aryl hydrocarbon receptor repressor DNA methylation in a Japanese population

  Tsuboi, Y., Yamada, H., Munetsuna, E., Fujii, R., Yamazaki, M., Ando, Y., Mizuno, G., Hattori, Y., Ishikawa, H., Ohashi, K., Hashimoto, S., Hamajima, N. & Suzuki, K., 11-2022, In: Nutrition Research. 107, p. 206-217 12 p.

  研究成果: Article › 査読

  • Provitamins 100%
  • Aryl Hydrocarbon Receptors 80%
  • Vegetables 61%
  • DNA Methylation 61%
  • Fruit 58%
• 2021

  Analysis of Repeated Measurements of Serum Carotenoid Levels and All-Cause and Cause-Specific Mortality in Japan

  Fujii, R., Tsuboi, Y., Maeda, K., Ishihara, Y. & Suzuki, K., 11-06-2021, In: JAMA network open. 4, 6, e2113369.

  研究成果: Article › 査読

  Open Access

  • Carotenoids 100%
  • Japan 68%
  • Mortality 41%
  • Serum 37%
  • Cardiovascular Diseases 27%
  4 被引用数 (Scopus)

• Association between circulating microRNAs and changes in kidney function: A five-year prospective study among Japanese adults without CKD

  Fujii, R., Yamada, H., Tsuboi, Y., Ando, Y., Munetsuna, E., Yamazaki, M., Ohashi, K., Ishikawa, H., Ishihara, Y., Hashimoto, S., Hamajima, N. & Suzuki, K., 10-2021, In: Clinica Chimica Acta. 521, p. 97-103 7 p.

  研究成果: Article › 査読

  • Circulating MicroRNA 100%
  • MicroRNA 87%
  • Chronic Renal Insufficiency 65%
  • Serum Level 48%
  • MicroRNAs 48%
  1 被引用数 (Scopus)

• Dietary fish and ω-3 polyunsaturated fatty acids are associated with leukocyte ABCA1 DNA methylation levels

  Fujii, R., Yamada, H., Munetsuna, E., Yamazaki, M., Mizuno, G., Ando, Y., Maeda, K., Tsuboi, Y., Ohashi, K., Ishikawa, H., Hagiwara, C., Wakai, K., Hashimoto, S., Hamajima, N. & Suzuki, K., 01-2021, In: Nutrition. 81, 110951.

  研究成果: Article › 査読

  • ATP-Binding Cassette Transporters 100%
  • Unsaturated Fatty Acids 90%
  • DNA Methylation 83%
  • Fishes 77%
  • Leukocytes 66%
  13 被引用数 (Scopus)

• Global DNA hypermethylation in peripheral blood mononuclear cells and cardiovascular disease risk: A population-based propensity score-matched cohort study

  Tsuboi, Y., Yamada, H., Munetsuna, E., Fujii, R., Yamazaki, M., Ando, Y., Mizuno, G., Ishikawa, H., Ohashi, K., Hashimoto, S., Hamajima, N. & Suzuki, K., 01-09-2021, In: Journal of Epidemiology and Community Health. 75, 9, p. 890-895 6 p.

  研究成果: Article › 査読

  • cardiovascular disease 100%
  • Propensity Score 85%
  • Blood Cells 65%
  • Cardiovascular Diseases 57%
  • DNA Methylation 55%
  1 被引用数 (Scopus)
• 2020

  Association of smoking habits with TXNIP DNA methylation levels in leukocytes among general Japanese population

  Maeda, K., Yamada, H., Munetsuna, E., Fujii, R., Yamazaki, M., Ando, Y., Mizuno, G., Ishikawa, H., Ohashi, K., Tsuboi, Y., Hashimoto, S., Hamajima, N. & Suzuki, K., 07-2020, In: PloS one. 15, 7, e0235486.

  研究成果: Article › 査読

  Open Access

  • Thioredoxins 100%
  • DNA Methylation 78%
  • Leukocytes 63%
  • Smoking 57%
  • Smokers 33%
  7 被引用数 (Scopus)
• 2019

  Associations between dietary vitamin intake, ABCA1 gene promoter DNA methylation, and lipid profiles in a Japanese population

  Fujii, R., Yamada, H., Munetsuna, E., Yamazaki, M., Ando, Y., Mizuno, G., Tsuboi, Y., Ohashi, K., Ishikawa, H., Hagiwara, C., Maeda, K., Hashimoto, S. & Suzuki, K., 01-11-2019, In: American Journal of Clinical Nutrition. 110, 5, p. 1213-1219 7 p.

  研究成果: Article › 査読

  • ATP-Binding Cassette Transporters 100%
  • Vitamins 83%
  • DNA Methylation 83%
  • Lipids 55%
  • Cardiovascular Diseases 38%
  17 被引用数 (Scopus)

• Associations of serum microRNA-20a, -27a, and -103a with cognitive function in a Japanese population: The Yakumo study

  Kondo, M., Yamada, H., Munetsuna, E., Yamazaki, M., Hatta, T., Iwahara, A., Ohashi, K., Ishikawa, H., Tsuboi, Y., Inoue, T., Fujii, R. & Suzuki, K., 01-05-2019, In: Archives of Gerontology and Geriatrics. 82, p. 155-160 6 p.

  研究成果: Article › 査読

  • mental state 100%
  • MicroRNAs 93%
  • Mental Status and Dementia Tests 91%
  • Cognition 87%
  • cognitive impairment 81%
  15 被引用数 (Scopus)

• Dietary vegetable intake is inversely associated with ATP-binding cassette protein A1 (ABCA1) DNA methylation levels among Japanese women

  Fujii, R., Yamada, H., Munetsuna, E., Yamazaki, M., Mizuno, G., Tsuboi, Y., Ohashi, K., Ishikawa, H., Ando, Y., Hagiwara, C., Maeda, K., Hashimoto, S., Hamajima, N. & Suzuki, K., 09-2019, In: Nutrition. 65, p. 1-5 5 p.

  研究成果: Article › 査読

  • Vegetables 100%
  • DNA Methylation 99%
  • Carrier Proteins 85%
  • Adenosine Triphosphate 78%
  • Cardiovascular Diseases 27%
  7 被引用数 (Scopus)
• 2018

  Association of subcutaneous and visceral fat with circulating microRNAs in a middle-aged Japanese population

  Munetsuna, E., Yamada, H., Ando, Y., Yamazaki, M., Tsuboi, Y., Kondo, M., Mizuno, G., Ishikawa, H., Sugimoto, K., Osakabe, K., Ichino, N., Ohashi, K., Hamajima, N. & Suzuki, K., 01-07-2018, In: Annals of Clinical Biochemistry. 55, 4, p. 437-445 9 p.

  研究成果: Article › 査読

  • Circulating MicroRNA 100%
  • MicroRNA 87%
  • Subcutaneous Fat 80%
  • Intra-Abdominal Fat 80%
  • Fat 70%
  15 被引用数 (Scopus)

• Relationship between long interspersed nuclear element-1 DNA methylation in leukocytes and dyslipidemia in the Japanese general population

  Tsuboi, Y., Yamada, H., Munetsuna, E., Yamazaki, M., Mizuno, G., Murase, Y., Ohashi, K., Ishikawa, H., Kondo, M., Inoue, T., Hashimoto, S., Hamajima, N. & Suzuki, K., 2018, In: Journal of atherosclerosis and thrombosis. 25, 12, p. 1231-1239 9 p.

  研究成果: Article › 査読

  • DNA Methylation 100%
  • Dyslipidemias 99%
  • Leukocytes 80%
  • Lipid 69%
  • Odds Ratio 65%
  14 被引用数 (Scopus)