研究成果の検索

2020

Antitumor activity of cyclin-dependent kinase inhibitor alsterpaullone in Epstein-Barr virus-associated lymphoproliferative disorders

Watanabe, T., Sato, Y., Masud, H. M. A. A., Takayama, M., Matsuda, H., Hara, Y., Yanagi, Y., Yoshida, M., Goshima, F., Murata, T. & Kimura, H., 01-01-2020, : : Cancer science. 111, 1, p. 279-287 9 p.

研究成果: Article

公開
Lymphoproliferative Disorders
Cyclin-Dependent Kinases
Human Herpesvirus 4
Therapeutic Uses
G1 Phase Cell Cycle Checkpoints

A patient with bullous pemphigoid with mucosal involvement serologically positive for anti-BP230 autoantibodies only

Taki, T., Takeichi, T., Kono, M., Sugiura, K., Sugimura, Y., Ishii, N., Hashimoto, T. & Akiyama, M., 01-01-2020, : : British Journal of Dermatology. 182, 1, p. 221-223 3 p.

研究成果: Letter

Bullous Pemphigoid
Autoantibodies

Evaluation of a weighted genetic risk score for the prediction of biomarkers of CYP2A6 activity

El-Boraie, A., Taghavi, T., Chenoweth, M. J., Fukunaga, K., Mushiroda, T., Kubo, M., Lerman, C., Nollen, N. L., Benowitz, N. L. & Tyndale, R. F., 01-01-2020, : : Addiction Biology. 25, 1, e12741.

研究成果: Article

Nicotine
Biomarkers
Cotinine
Phenotype
Smoking

Intermittent hypoxia, energy expenditure, and visceral adipocyte recovery

Umeda, A., Miyagawa, K., Mochida, A., Takeda, H., Takeda, K., Okada, Y. & Gozal, D., 02-2020, : : Respiratory Physiology and Neurobiology. 273, 103332.

研究成果: Article

Adipocytes
Energy Metabolism
White Adipocytes
Body Weight
Hypoxia
Neural networks
Lung
Multiple Pulmonary Nodules
Biopsy
Tuning

Polygenic risk scores in schizophrenia with clinically significant copy number variants

Taniguchi, S., Ninomiya, K., Kushima, I., Saito, T., Shimasaki, A., Sakusabe, T., Momozawa, Y., Kubo, M., Kamatani, Y., Ozaki, N., Ikeda, M. & Iwata, N., 01-01-2020, : : Psychiatry and clinical neurosciences. 74, 1, p. 35-39 5 p.

研究成果: Article

公開
Schizophrenia
Comparative Genomic Hybridization
Single Nucleotide Polymorphism

Prognostic impact of C-reactive protein-albumin ratio for the lethality in castration-resistant prostate cancer

Uchimoto, T., Komura, K., Fujiwara, Y., Saito, K., Tanda, N., Matsunaga, T., Ichihashi, A., Tsutsumi, T., Tsujino, T., Yoshikawa, Y., Nishimoto, Y., Takai, T., Minami, K., Taniguchi, K., Tanaka, T., Uehara, H., Hirano, H., Nomi, H., Ibuki, N., Takahara, K. および2人, Inamoto, T. & Azuma, H., 01-01-2020, : : Medical Oncology. 37, 1, 9.

研究成果: Article

Castration
C-Reactive Protein
Albumins
Prostatic Neoplasms
docetaxel
1 引用 (Scopus)

Scientific frontiers in faecal microbiota transplantation: joint document of Asia-Pacific Association of Gastroenterology (APAGE) and Asia-Pacific Society for Digestive Endoscopy (APSDE)

Ng, S. C., Kamm, M. A., Yeoh, Y. K., Chan, P. K. S., Zuo, T., Tang, W., Sood, A., Andoh, A., Ohmiya, N., Zhou, Y., Ooi, C. J., Mahachai, V., Wu, C. Y., Zhang, F., Sugano, K. & Chan, F. K. L., 01-01-2020, : : Gut. 69, 1, p. 83-91 9 p.

研究成果: Article

公開
Gastroenterology
Endoscopy
Joints
Microbiota
Tissue Donors

The difference in determinant factor of six-minute walking distance between sarcopenic and non-sarcopenic elderly patients with heart failure

Kono, Y., Izawa, H., Aoyagi, Y., Ishikawa, A., Sugiura, T., Mori, E., Ueda, S., Fujiwara, W., Hayashi, M. & Saitoh, E., 01-2020, : : Journal of cardiology. 75, 1, p. 42-46 5 p.

研究成果: Article

Sarcopenia
Walking
Heart Failure
Muscle Strength
Knee

The quantification of task-difficulty of upper limb motor function skill based on Rasch analysis

Miyasaka, H., Kondo, I., Yamamura, C., Fujita, N., Orand, A. & Sonoda, S., 02-01-2020, : : Topics in Stroke Rehabilitation. 27, 1, p. 49-56 8 p.

研究成果: Article

Motor Skills
Upper Extremity
Paralysis
Stroke
Numismatics
2019
2 引用 (Scopus)

5-HT 1A receptor agonist 8-OH-DPAT induces serotonergic behaviors in mice via interaction between PKCδ and p47phox

Tran, H. Q., Shin, E. J., Hoai Nguyen, B. C., Phan, D. H., Kang, M. J., Jang, C. G., Jeong, J. H., Nah, S. Y., Mouri, A., Saito, K., Nabeshima, T. & Kim, H. C., 01-01-2019, : : Food and Chemical Toxicology. 123, p. 125-141 17 p.

研究成果: Article

8-Hydroxy-2-(di-n-propylamino)tetralin
Receptor, Serotonin, 5-HT1A
serotonin
agonists
Serotonin

A 20-year prospective longitudinal MRI study on cervical spine after whiplash injury: Follow-up of a cross-sectional study

Daimon, K., Fujiwara, H., Nishiwaki, Y., Okada, E., Nojiri, K., Shimizu, K., Ishihama, H., Fujita, N., Ichihara, D., Tsuji, T., Nakamura, M., Matsumoto, M. & Watanabe, K., 01-07-2019, : : Journal of Orthopaedic Science. 24, 4, p. 579-583 5 p.

研究成果: Article

Whiplash Injuries
Longitudinal Studies
Spine
Neck Pain
Cross-Sectional Studies

A case of dihydropyrimidinase deficiency incidentally detected by urine metabolome analysis

Tsuchiya, H., Akiyama, T., Kuhara, T., Nakajima, Y., Ohse, M., Kurahashi, H., Kato, T., Maeda, Y., Yoshinaga, H. & Kobayashi, K., 01-03-2019, : : Brain and Development. 41, 3, p. 280-284 5 p.

研究成果: Article

Metabolome
Urine
Mutation
Fluorouracil
Metabolomics
1 引用 (Scopus)

A case of early onset life-threatening epilepsy associated with a novel ATP1A3 gene variant

Ishihara, N., Inagaki, H., Miyake, M., Kawamura, Y., Yoshikawa, T. & Kurahashi, H., 01-03-2019, : : Brain and Development. 41, 3, p. 285-291 7 p.

研究成果: Article

Epilepsy
Mutation
Genes
Respiratory Insufficiency
Parents
公開
Lymphoproliferative Disorders
Leiomyosarcoma
Kidney Transplantation
Human Herpesvirus 4
Biopsy
Signet Ring Cell Carcinoma
Human papillomavirus 16
Cervix Uteri
Genome
Neoplasms

A case of uterine lymphangioleiomyomatosis in a young woman that was identified via peritonitis

Yoshizawa, H., Kawai, S., Hirota, Y., Ueda, T., Kuroda, M. & Fujii, T., 01-02-2019, : : Journal of Obstetrics and Gynaecology Research. 45, 2, p. 482-486 5 p.

研究成果: Article

Lymphangioleiomyomatosis
Peritonitis
Tuberous Sclerosis
Ovariectomy
Hysterectomy

A CO2 removal system using extracorporeal lung and renal assist device with an acid and alkaline infusion

Takahashi, N., Nakada, T. A., Sakai, T., Kato, Y., Moriyama, K., Nishida, O. & Oda, S., 01-01-2019, (Accepted/In press) : : Journal of Artificial Organs.

研究成果: Article

Membranes
Kidney
Equipment and Supplies
Lung
Acids
Cognition
Alzheimer Disease
Magnetic Resonance Imaging
Neuropsychological Tests
Atrophy

A complementary scheme for automated detection of high-uptake regions on dedicated breast PET and whole-body PET/CT

Minoura, N., Teramoto, A., Ito, A., Yamamuro, O., Nishio, M., Saito, K. & Fujita, H., 01-09-2019, : : Radiological Physics and Technology. 12, 3, p. 260-267 8 p.

研究成果: Article

breast
Breast
tomography
Tomography
Axilla

A constitutional jumping translocation involving the y and acrocentric chromosomes

Tsutsumi, M., Fujita, N., Suzuki, F., Mishima, T., Fujieda, S., Watari, M., Takahashi, N., Tonoki, H., Moriwaka, O., Endo, T. & Kurahashi, H., 01-01-2019, : : Asian Journal of Andrology. 21, 1, p. 101-103 3 p.

研究成果: Letter

Chromosomes

Acquired expression of mutant mitofusin 2 causes progressive neurodegeneration and abnormal behavior

Ishikawa, K., Yamamoto, S., Hattori, S., Nishimura, N., Tani, H., Mito, T., Matsumoto, H., Miyakawa, T. & Nakada, K., 27-02-2019, : : Journal of Neuroscience. 39, 9, p. 1588-1604 17 p.

研究成果: Article

Mitochondrial Dynamics
Neurodegenerative Diseases
Neurons
Memory Disorders
Learning

Activities of daily living among elderly persons with severe aortic stenosis

Fukui, S., Kawakami, M., Otaka, Y., Ishikawa, A., Yashima, F., Hayashida, K., Muraoka, K. & Liu, M., 01-01-2019, : : Disability and Rehabilitation.

研究成果: Article

Aortic Valve Stenosis
Activities of Daily Living
Cerebrovascular Disorders
Heart Failure
Nutritional Status
AMPA Receptors
Social Behavior
Ketamine
N-Methyl-D-Aspartate Receptors
Acids

ADAMTS8 Promotes the Development of Pulmonary Arterial Hypertension and Right Ventricular Failure: A Possible Novel Therapeutic Target

Omura, J., Satoh, K., Kikuchi, N., Satoh, T., Kurosawa, R., Nogi, M., Ohtsuki, T., Al-Mamun, M. E., Siddique, M. A. H., Yaoita, N., Sunamura, S., Miyata, S., Hoshikawa, Y., Okada, Y. & Shimokawa, H., 25-10-2019, : : Circulation research. 125, 10, p. 884-906 23 p.

研究成果: Article

Pulmonary Hypertension
Smooth Muscle Myocytes
Pulmonary Artery
Therapeutics
Cell Proliferation

A decision tree-based survival analysis of patients with a history of inappropriate implantable cardioverter-defibrillator therapy

Yamamoto, M., Okajima, K., Shimane, A., Ozawa, T., Morishima, I., Asai, T., Takagi, M., Kasai, A., Fujii, E., Kiyono, K., Watanabe, E. & Ozaki, Y., 01-01-2019, : : International heart journal. 60, 2, p. 318-326 9 p.

研究成果: Article

公開
Decision Trees
Implantable Defibrillators
Survival Analysis
Decision Support Techniques
Therapeutics
13 引用 (Scopus)

Adiposity and risk of decline in glomerular filtration rate: Meta-analysis of individual participant data in a global consortium

Chang, A. R., Grams, M. E., Ballew, S. H., Bilo, H., Correa, A., Evans, M., Gutierrez, O. M., Hosseinpanah, F., Iseki, K., Kenealy, T., Klein, B., Kronenberg, F., Lee, B. J., Li, Y., Miura, K., Navaneethan, S. D., Roderick, P. J., Valdivielso, J. M., Visseren, F. L. J., Zhang, L. および6人, Gansevoort, R. T., Hallan, S. I., Levey, A. S., Matsushita, K., Shalev, V. & Woodward, M., 01-01-2019, : : BMJ (Online). 364, k5301.

研究成果: Article

Adiposity
Glomerular Filtration Rate
Meta-Analysis
Body Mass Index
Waist Circumference
Intraabdominal Infections
Colistin
Acinetobacter baumannii
Carbapenems
Bacteremia

Admission heart rate is a determinant of effectiveness of beta-blockers in acute myocardial infarction patients

on behalf of J-MINUET Investigators, 01-01-2019, : : Circulation Journal. 83, 5, p. 1054-1063 10 p.

研究成果: Article

公開
Heart Rate
Myocardial Infarction
Bradycardia
Unstable Angina
Tachycardia
1 引用 (Scopus)
Indigo Carmine
Ulcerative Colitis
Pulmonary Hypertension
Intussusception
Liver Diseases
公開
Hypogonadism
Testicular Neoplasms
Multicenter Studies
Survivors
Drug Therapy

A female patient with retinoblastoma and severe intellectual disability carrying an X;13 balanced translocation without rearrangement in the RB1 gene: A case report

Tsutsumi, M., Hattori, H., Akita, N., Maeda, N., Kubota, T., Horibe, K., Fujita, N., Kawai, M., Shinkai, Y., Kato, M., Kato, T., Kawamura, R., Suzuki, F. & Kurahashi, H., 05-12-2019, : : BMC Medical Genomics. 12, 1, 182.

研究成果: Article

公開
Retinoblastoma
Intellectual Disability
X Chromosome Inactivation
Genes
Cytogenetic Analysis
2 引用 (Scopus)

A genome-wide association study of coping behaviors suggests FBXO45 is associated with emotional expression

Shimanoe, C., Hachiya, T., Hara, M., Nishida, Y., Tanaka, K., Sutoh, Y., Shimizu, A., Hishida, A., Kawai, S., Okada, R., Tamura, T., Matsuo, K., Ito, H., Ozaki, E., Matsui, D., Ibusuki, R., Shimoshikiryo, I., Takashima, N., Kadota, A., Arisawa, K. および12人, Uemura, H., Suzuki, S., Watanabe, M., Kuriki, K., Endoh, K., Mikami, H., Nakamura, Y., Momozawa, Y., Kubo, M., Nakatochi, M., Naito, M. & Wakai, K., 01-02-2019, : : Genes, Brain and Behavior. 18, 2, e12481.

研究成果: Article

Genome-Wide Association Study
Psychological Adaptation
Genes
Regulator Genes
Synapses
公開
Inbred C57BL Mouse
Locomotion
Fear
Startle Reflex
Anxiety

Allergic contact dermatitis caused by tetrahydrofurfuryl acrylate in the adhesive of clip-on earrings

Suzuki, K., Matsunaga, K., Sasaki, K. & Yagami, A., 01-01-2019, (Accepted/In press) : : Contact Dermatitis. 82, 2, p. 131-133 3 p.

研究成果: Article

Allergic Contact Dermatitis
Contact Dermatitis
Surgical Instruments
Adhesives
acrylic acid
2 引用 (Scopus)

Alteration of specific cytokine expression patterns in patients with breast cancer

Kawaguchi, K., Sakurai, M., Yamamoto, Y., Suzuki, E., Tsuda, M., Kataoka, T. R., Hirata, M., Nishie, M., Nojiri, T., Kumazoe, M., Saito, K. & Toi, M., 01-12-2019, : : Scientific reports. 9, 1, 2924.

研究成果: Article

公開
Breast Neoplasms
Cytokines
Healthy Volunteers
Interleukin-1
Interleukin-9
公開
Kynurenine
Knockout Mice
Biomarkers
Attention Deficit Disorder with Hyperactivity
Impulsive Behavior
2 引用 (Scopus)

Altered regulation of serum lysosomal acid hydrolase activities in Parkinson's disease: A potential peripheral biomarker?

Niimi, Y., Ito, S., Mizutani, Y., Murate, K., Shima, S., Ueda, A., Satake, W., Hattori, N., Toda, T. & Mutoh, T., 01-04-2019, : : Parkinsonism and Related Disorders. 61, p. 132-137 6 p.

研究成果: Article

Galactosidases
Hydrolases
Parkinson Disease
Parkinsonian Disorders
Biomarkers
Textbooks
Information use
Lung
Education
Students
公開
Ascites
Albumins
Therapeutics
Serum Albumin
Paracentesis
machine learning
Mammography
breast
lesions
Breast

Amplified association between blood pressure and albuminuria in overweight patients with biopsy-proven hypertensive nephrosclerosis

Research Group of Diabetic Nephropathy and Nephrosclerosis, Ministry of Health, Labour and Welfare of Japan & Japan Agency for Medical Research and Development, 01-01-2019, : : American Journal of Hypertension. 32, 5, p. 486-491 6 p.

研究成果: Article

Nephrosclerosis
Albuminuria
Blood Pressure
Biopsy
Glomerular Filtration Rate
1 引用 (Scopus)

A multicenter, open-label, single-arm study of anamorelin (ONO-7643) in advanced gastrointestinal cancer patients with cancer cachexia

Hamauchi, S., Furuse, J., Takano, T., Munemoto, Y., Furuya, K., Baba, H., Takeuchi, M., Choda, Y., Higashiguchi, T., Naito, T., Muro, K., Takayama, K., Oyama, S., Takiguchi, T., Komura, N. & Tamura, K., 01-12-2019, : : Cancer. 125, 23, p. 4294-4302 9 p.

研究成果: Article

公開
Cachexia
Gastrointestinal Neoplasms
Neoplasms
Appetite
Body Weight

A multicenter trial of extracorporeal cardiac shock wave therapy for refractory angina pectoris: report of the highly advanced medical treatment in Japan

Kikuchi, Y., Ito, K., Shindo, T., Hao, K., Shiroto, T., Matsumoto, Y., Takahashi, J., Matsubara, T., Yamada, A., Ozaki, Y., Hiroe, M., Misumi, K., Ota, H., Takanami, K., Hiraide, T., Takase, K., Tanji, F., Tomata, Y., Tsuji, I. & Shimokawa, H., 22-01-2019, : : Heart and Vessels. 34, 1, p. 104-113 10 p.

研究成果: Article

Convulsive Therapy
Angina Pectoris
Multicenter Studies
Japan
Heart Ventricles

Analysis of multiscale entropy characteristics of heart rate variability in patients with permanent atrial fibrillation for predicting ischemic stroke risk

Matsuoka, R., Yoshino, K., Watanabe, E. & Kiyono, K., 21-01-2019, Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018. Schmidt, H., Griol, D., Wang, H., Baumbach, J., Zheng, H., Callejas, Z., Hu, X., Dickerson, J. & Zhang, L. (版). Institute of Electrical and Electronics Engineers Inc., 1 p. 8621178. (Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018).

研究成果: Conference contribution

Entropy
Atrial Fibrillation
Heart Rate
Stroke
Probability density function
Induced Pluripotent Stem Cells
Dendritic Cells
Monocytes
Mites
HLA-DR Antigens

Anaphylaxis to xylitol diagnosed by skin prick test and basophil activation test

Okamoto, K., Kagami, M., Kawai, M., Mori, Y., Yamawaki, K., Nakajima, Y., Kondo, Y. & Tsuge, I., 01-2019, : : Allergology International. 68, 1, p. 130-131 2 p.

研究成果: Letter

Xylitol
Basophils
Anaphylaxis
Skin Tests

Anastrozole Aromatase Inhibitor Plasma Drug Concentration Genome-Wide Association Study: Functional Epistatic Interaction Between SLC38A7 and ALPPL2

Dudenkov, T. M., Liu, D., Cairns, J., Devarajan, S., Zhuang, Y., Ingle, J. N., Buzdar, A. U., Robson, M. E., Kubo, M., Batzler, A., Barman, P., Jenkins, G. D., Carlson, E. E., Goetz, M. P., Northfelt, D. W., Moreno-Aspitia, A., Desta, Z., Reid, J. M., Kalari, K. R., Wang, L. および1人, Weinshilboum, R. M., 01-07-2019, : : Clinical Pharmacology and Therapeutics. 106, 1, p. 219-227 9 p.

研究成果: Article

公開
Aromatase Inhibitors
Genome-Wide Association Study
Single Nucleotide Polymorphism
Pharmaceutical Preparations
Breast Neoplasms
4 引用 (Scopus)
Major Histocompatibility Complex
Vertebrates
Peptides
Amphibians
Zebrafish

An effective and promising treatment with adalimumab for impetigo herpetiformis with postpartum flare-up

Yamashita, T., Hamada, T., Maruta, Y., Kajita, A., Hirai, Y., Morizane, S., Watanabe, S., Sugiura, K. & Iwatsuki, K., 03-2019, : : International Journal of Dermatology. 58, 3, p. 350-353 4 p.

研究成果: Article

Impetigo
Postpartum Period
Adalimumab