研究成果の検索

2019

5-HT 1A receptor agonist 8-OH-DPAT induces serotonergic behaviors in mice via interaction between PKCδ and p47phox

Tran, H. Q., Shin, E. J., Hoai Nguyen, B. C., Phan, D. H., Kang, M. J., Jang, C. G., Jeong, J. H., Nah, S. Y., Mouri, A., Saito, K., Nabeshima, T. & Kim, H. C., 01-01-2019, : : Food and Chemical Toxicology. 123, p. 125-141 17 p.

研究成果: Article

8-Hydroxy-2-(di-n-propylamino)tetralin
Receptor, Serotonin, 5-HT1A
serotonin
agonists
Serotonin

A case of dihydropyrimidinase deficiency incidentally detected by urine metabolome analysis

Tsuchiya, H., Akiyama, T., Kuhara, T., Nakajima, Y., Ohse, M., Kurahashi, H., Kato, T., Maeda, Y., Yoshinaga, H. & Kobayashi, K., 01-03-2019, : : Brain and Development. 41, 3, p. 280-284 5 p.

研究成果: Article

Metabolome
Urine
Mutation
Fluorouracil
Metabolomics

A case of early onset life-threatening epilepsy associated with a novel ATP1A3 gene variant

Ishihara, N., Inagaki, H., Miyake, M., Kawamura, Y., Yoshikawa, T. & Kurahashi, H., 01-03-2019, : : Brain and Development. 41, 3, p. 285-291 7 p.

研究成果: Article

Epilepsy
Mutation
Genes
Respiratory Insufficiency
Parents
Signet Ring Cell Carcinoma
Human papillomavirus 16
Cervix Uteri
Genome
Neoplasms
Cognition
Alzheimer Disease
Magnetic Resonance Imaging
Neuropsychological Tests
Atrophy

A constitutional jumping translocation involving the y and acrocentric chromosomes

Tsutsumi, M., Fujita, N., Suzuki, F., Mishima, T., Fujieda, S., Watari, M., Takahashi, N., Tonoki, H., Moriwaka, O., Endo, T. & Kurahashi, H., 01-01-2019, : : Asian Journal of Andrology. 21, 1, p. 101-103 3 p.

研究成果: Letter

Chromosomes
AMPA Receptors
Social Behavior
Ketamine
N-Methyl-D-Aspartate Receptors
Acids

A decision tree-based survival analysis of patients with a history of inappropriate implantable cardioverter-defibrillator therapy

Yamamoto, M., Okajima, K., Shimane, A., Ozawa, T., Morishima, I., Asai, T., Takagi, M., Kasai, A., Fujii, E., Kiyono, K., Watanabe, E. & Ozaki, Y., 01-01-2019, : : International heart journal. 60, 2, p. 318-326 9 p.

研究成果: Article

公開
Decision Trees
Implantable Defibrillators
Survival Analysis
Decision Support Techniques
Therapeutics

Adiposity and risk of decline in glomerular filtration rate: Meta-analysis of individual participant data in a global consortium

Chang, A. R., Grams, M. E., Ballew, S. H., Bilo, H., Correa, A., Evans, M., Gutierrez, O. M., Hosseinpanah, F., Iseki, K., Kenealy, T., Klein, B., Kronenberg, F., Lee, B. J., Ri, E., Miura, K., Navaneethan, S. D., Roderick, P. J., Valdivielso, J. M., Visseren, F. L. J., Zhang, L. および6人Gansevoort, R. T., Hallan, S. I., Levey, A. S., Matsushita, K., Shalev, V. & Woodward, M., 01-01-2019, : : BMJ (Online). 364, k5301.

研究成果: Article

Adiposity
Glomerular Filtration Rate
Meta-Analysis
Body Mass Index
Waist Circumference
Intraabdominal Infections
Colistin
Acinetobacter baumannii
Carbapenems
Bacteremia
公開
Hypogonadism
Testicular Neoplasms
Multicenter Studies
Drug Therapy
Survivors

A genome-wide association study of coping behaviors suggests FBXO45 is associated with emotional expression

Shimanoe, C., Hachiya, T., Hara, M., Nishida, Y., Tanaka, K., Sutoh, Y., Shimizu, A., Hishida, A., Kawai, S., Okada, R., Tamura, T., Matsuo, K., Ito, H., Ozaki, E., Matsui, D., Ibusuki, R., Shimoshikiryo, I., Takashima, N., Kadota, A., Arisawa, K. および12人Uemura, H., Suzuki, S., Watanabe, M., Kuriki, K., Endoh, K., Mikami, H., Nakamura, Y., Momozawa, Y., Kubo, M., Nakatochi, M., Naito, M. & Wakai, K., 01-02-2019, : : Genes, Brain and Behavior. 18, 2, e12481.

研究成果: Article

Genome-Wide Association Study
Psychological Adaptation
Genes
Regulator Genes
Synapses

Altered regulation of serum lysosomal acid hydrolase activities in Parkinson's disease: A potential peripheral biomarker?

Niimi, Y., Ito, S., Mizutani, Y., Murate, K., Shima, S., Ueda, A., Satake, W., Hattori, N., Toda, T. & Mutoh, T., 01-04-2019, : : Parkinsonism and Related Disorders. 61, p. 132-137 6 p.

研究成果: Article

Galactosidases
Hydrolases
Parkinson Disease
Parkinsonian Disorders
Biomarkers

A multicenter trial of extracorporeal cardiac shock wave therapy for refractory angina pectoris: report of the highly advanced medical treatment in Japan

Kikuchi, Y., Ito, K., Shindo, T., Hao, K., Shiroto, T., Matsumoto, Y., Takahashi, J., Matsubara, T., Yamada, A., Ozaki, Y., Hiroe, M., Misumi, K., Ota, H., Takanami, K., Hiraide, T., Takase, K., Tanji, F., Tomata, Y., Tsuji, I. & Shimokawa, H., 22-01-2019, : : Heart and Vessels. 34, 1, p. 104-113 10 p.

研究成果: Article

Convulsive Therapy
Angina Pectoris
Multicenter Studies
Japan
Heart Ventricles

Analysis of multiscale entropy characteristics of heart rate variability in patients with permanent atrial fibrillation for predicting ischemic stroke risk

Matsuoka, R., Yoshino, K., Watanabe, E. & Kiyono, K., 21-01-2019, Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018. Schmidt, H., Griol, D., Wang, H., Baumbach, J., Zheng, H., Callejas, Z., Hu, X., Dickerson, J. & Zhang, L. (版). Institute of Electrical and Electronics Engineers Inc., 1 p. 8621178. (Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018).

研究成果: Conference contribution

Entropy
Atrial Fibrillation
Heart Rate
Stroke
Probability density function

Anaphylaxis to xylitol diagnosed by skin prick test and basophil activation test

Okamoto, K., Kagami, M., Kawai, M., Mori, Y., Yamawaki, K., Nakajima, Y., Kondo, Y. & Tsuge, I., 01-01-2019, : : Allergology International. 68, 1, p. 130-131 2 p.

研究成果: Letter

Xylitol
Basophils
Anaphylaxis
Skin Tests

Anastrozole Aromatase Inhibitor Plasma Drug Concentration Genome-Wide Association Study: Functional Epistatic Interaction Between SLC38A7 and ALPPL2

Dudenkov, T. M., Liu, D., Cairns, J., Devarajan, S., Zhuang, Y., Ingle, J. N., Buzdar, A. U., Robson, M. E., Kubo, M., Batzler, A., Barman, P., Jenkins, G. D., Carlson, E. E., Goetz, M. P., Northfelt, D. W., Moreno-Aspitia, A., Desta, Z., Reid, J. M., Kalari, K. R., Wang, L. および1人Weinshilboum, R. M., 01-01-2019, : : Clinical Pharmacology and Therapeutics.

研究成果: Article

公開
Aromatase Inhibitors
Genome-Wide Association Study
Single Nucleotide Polymorphism
Pharmaceutical Preparations
Breast Neoplasms
2 引用 (Scopus)
Major Histocompatibility Complex
Vertebrates
Peptides
Amphibians
Zebrafish

An effective and promising treatment with adalimumab for impetigo herpetiformis with postpartum flare-up

Yamashita, T., Hamada, T., Maruta, Y., Kajita, A., Hirai, Y., Morizane, S., Watanabe, S., Sugiura, K. & Iwatsuki, K., 01-03-2019, : : International Journal of Dermatology. 58, 3, p. 350-353 4 p.

研究成果: Article

Impetigo
Postpartum Period
Adalimumab
1 引用 (Scopus)

Antimicrobial treatment challenges in the era of carbapenem resistance

Peri, A. M., Doi, Y., Potoski, B. A., Harris, P. N. A., Paterson, D. L. & Righi, E., 01-01-2019, : : Diagnostic Microbiology and Infectious Disease.

研究成果: Review article

Carbapenems
Anti-Bacterial Agents
Enterobacteriaceae Infections
Colistin
Aminoglycosides
1 引用 (Scopus)

A Pharmacogenetic Prediction Model of Progression-Free Survival in Breast Cancer using Genome-Wide Genotyping Data from CALGB 40502 (Alliance)

Rashkin, S. R., Chua, K. C., Ho, C., Mulkey, F., Jiang, C., Mushiroda, T., Kubo, M., Friedman, P. N., Rugo, H. S., McLeod, H. L., Ratain, M. J., Castillos, F., Naughton, M., Overmoyer, B., Toppmeyer, D., Witte, J. S., Owzar, K. & Kroetz, D. L., 01-03-2019, : : Clinical Pharmacology and Therapeutics. 105, 3, p. 738-745 8 p.

研究成果: Article

Pharmacogenetics
Disease-Free Survival
Area Under Curve
Genome
Breast Neoplasms

A prospective study of acinetobacter baumannii complex isolates and colistin susceptibility monitoring by mass spectrometry of microbial membrane glycolipids

Leung, L. M., McElheny, C. L., Gardner, F. M., Chandler, C. E., Bowler, S. L., Mettus, R. T., Spychala, C. N., Fowler, E. L., Opene, B. N. A., Myers, R. A., Goodlett, D. R., Doi, Y. & Ernst, R. K., 01-03-2019, : : Journal of clinical microbiology. 57, 3, e01100-18.

研究成果: Article

Colistin
Acinetobacter baumannii
Glycolipids
Mass Spectrometry
Prospective Studies

Association of Circulatory Iron Deficiency With an Enlarged Heart in Patients With End-Stage Kidney Disease

Hayashi, T., Tanaka, Y., Iwasaki, M., Hase, H., Yamamoto, H., Komatsu, Y., Ando, R., Ikeda, M., Inaguma, D., Sakaguchi, T., Shinoda, T., Koiwa, F., Negi, S., Yamaka, T., Shigematsu, T. & Joki, N., 01-01-2019, : : Journal of Renal Nutrition. 29, 1, p. 39-47 9 p.

研究成果: Article

Cardiomegaly
Chronic Kidney Failure
Iron
Hemoglobins
Transferrin

Association of gamma-glutamyl transferase and alanine aminotransferase with type 2 diabetes mellitus incidence in middle-aged Japanese men: 12-year follow up

Kaneko, K., Yatsuya, H., Ri, E., Uemura, M., Chiang, C., Hirakawa, Y., Ota, A., Tamakoshi, K. & Aoyama, A., 01-05-2019, : : Journal of Diabetes Investigation. 10, 3, p. 837-845 9 p.

研究成果: Article

Transferases
Alanine Transaminase
Diabetes Mellitus
Incidence
Triglycerides

Association of genetic polymorphisms in DNMT3A with the progression of gastric mucosal atrophy and susceptibility to gastric cancer in Japan

Jing, W., Otsuka, T., Nakamura, M., Sakurai, N., Takano, H., Hayashi, T., Ota, M., Nomura, T., Hayashi, R., Shimasaki, T., Tahara, T., Shibata, T. & Arisawa, T., 01-03-2019, : : Oncology Letters. 17, 3, p. 3482-3488 7 p.

研究成果: Article

公開
Genetic Polymorphisms
Stomach Neoplasms
Atrophy
Stomach
Japan

Associations of coronary plaque characteristics by integrated backscatter intravascular ultrasound with detectability of vessel external elastic lamina using optical frequency domain imaging in human coronary arteries: A sub-analysis of the MISTIC-1 trial

Ishikawa, M., Muramatsu, T., Nanasato, M., Nagasaka, R., Takatsu, H., Yoshiki, Y., Hashimoto, Y., Ohota, M., Okumura, M., Naruse, H., Ishii, J., Ito, K., Takahashi, H., Kamiya, H., Yoshida, Y. & Ozaki, Y., 01-01-2019, : : Catheterization and Cardiovascular Interventions.

研究成果: Article

Stents
Coronary Vessels
Lipids
Light
Atherosclerotic Plaques

Associations of serum microRNA-20a, -27a, and -103a with cognitive function in a Japanese population: The Yakumo study

Kondo, M., Yamada, H., Munetsuna, E., Yamazaki, M., Hatta, T., Iwahara, A., Ohashi, K., Ishikawa, H., Tsuboi, Y., Inoue, T., Fujii, R. & Suzuki, K., 01-05-2019, : : Archives of Gerontology and Geriatrics. 82, p. 155-160 6 p.

研究成果: Article

MicroRNAs
Cognition
examination
Serum
Population
1 引用 (Scopus)

Astrocytic mobilization of glutathione peroxidase-1 contributes to the protective potential against cocaine kindling behaviors in mice via activation of JAK2/STAT3 signaling

Mai, H. N., Nguyen, L. T. T., Shin, E. J., Kim, D. J., Jeong, J. H., Chung, Y. H., Lei, X. G., Sharma, N., Jang, C. G., Nabeshima, T. & Kim, H. C., 01-02-2019, : : Free Radical Biology and Medicine. 131, p. 408-431 24 p.

研究成果: Article

Cocaine
Chemical activation
Glial Fibrillary Acidic Protein
Oxidative stress
Hippocampus

Automated Feedback Messages With Shichifukujin Characters Using IoT System-Improved Glycemic Control in People With Diabetes: A Prospective, Multicenter Randomized Controlled Trial

Kobayashi, T., Tsushita, K., Nomura, E., Muramoto, A., Kato, A., Eguchi, Y., Onoue, T., Goto, M., Muto, S., Yatsuya, H. & Arima, H., 01-01-2019, : : Journal of Diabetes Science and Technology.

研究成果: Letter

Tomography
Biopsy
Neural networks
Lung
Lung Neoplasms

Bacterial stabilization of a panel of picornaviruses

Aguilera, E. R., Nguyen, Y., Sasaki, J. & Pfeiffer, J. K., 01-03-2019, : : mSphere. 4, 2, e00183-19.

研究成果: Article

公開
Picornaviridae
Poliovirus
Enterovirus
Kobuvirus
Bacteria

Bactericidal/Permeability-Increasing Fold-Containing Family B Member 4 May Be Associated with NSAID-Induced Enteropathy

Fujimori, S., Fukunaga, K., Takahashi, A., Mushiroda, T., Kubo, M., Hanada, R., Hayashida, M., Sakurai, T., Iwakiri, K. & Sakamoto, C., 15-02-2019, : : Digestive Diseases and Sciences. 64, 2, p. 401-408 8 p.

研究成果: Article

Single Nucleotide Polymorphism
Permeability
Anti-Inflammatory Agents
Genome-Wide Association Study
Celecoxib
1 引用 (Scopus)
公開
metastasis
cancer
Neoplasm Metastasis
Proteins
Messenger RNA

Can electric fields explain inter-individual variability in transcranial direct current stimulation of the motor cortex?

Laakso, I., Mikkonen, M., Koyama, S., Hirata, A. & Tanaka, S., 01-12-2019, : : Scientific Reports. 9, 1, 626.

研究成果: Article

Motor Cortex
Motor Evoked Potentials
Individuality
Cross-Over Studies
Transcranial Direct Current Stimulation

Capsule endoscopy findings for the diagnosis of Crohn’s disease: a nationwide case–control study

Esaki, M., Matsumoto, T., Omiya, N., Washio, E., Morishita, T., Sakamoto, K., Abe, H., Yamamoto, S., Kinjo, T., Togashi, K., Watanabe, K., Hirai, F., Nakamura, M., Nouda, S., Ashizuka, S., Omori, T., Kochi, S., Yanai, S., Fuyuno, Y., Hirano, A. および6人Umeno, J., Kitazono, T., Kinjo, F., Watanabe, M., Matsui, T. & Suzuki, Y., 15-03-2019, : : Journal of Gastroenterology. 54, 3, p. 249-260 12 p.

研究成果: Article

Capsule Endoscopy
Crohn Disease
Ulcer
Observer Variation
Early Diagnosis

Carotid artery plaque screening using abdominal aortic calcification on lumbar radiographs

Kobayashi, K., Ando, K., Seki, T., Hamada, T., Suzuki, K., Ishiguro, N., Hasegawa, Y. & Imagama, S., 01-01-2019, : : PLoS One. 14, 1, e0209175.

研究成果: Article

carotid arteries
Carotid Stenosis
calcification
Medical problems
Screening

Case of anaphylaxis caused by black ginger in a dietary supplement

Hayashi, E., Sowa-Osako, J., Fukai, K., Natsumi, A., Yagami, A., Sato, N., Shimojo, N., Nakamura, M., Matsunaga, K. & Tsuruta, D., 01-02-2019, : : Journal of Dermatology. 46, 2, p. e56-e57

研究成果: Letter

Ginger
Anaphylaxis
Dietary Supplements

Case of generalized pustular psoriasis with coexisting mutations in IL36RN and CARD14

Sawabe, Y., Hayashi, K., Kamata, M., Nagata, M., Fukaya, S., Fukuyasu, A., Tanaka, T., Ishikawa, T., Ohnishi, T., Komatsu, H., Tanaka, M., Sugiura, K. & Tada, Y., 01-01-2019, : : Journal of Dermatology.

研究成果: Letter

Psoriasis
Mutation

CD36 gene polymorphism (rs1761667) is associated with dietary monounsaturated fatty acid intake and hypertension in a Japanese population

Fujii, R., Hishida, A., Suzuki, K., Imaeda, N., Goto, C., Hamajima, N., Wakai, K. & Kondo, T., 01-01-2019, : : British Journal of Nutrition.

研究成果: Article

Monounsaturated Fatty Acids
Blood Pressure
Hypertension
Population
Genes

Chronic cerebral hypoperfusion upregulates leptin receptor expression in astrocytes and tau phosphorylation in tau transgenic mice

Shimada, T., Shindo, A., Matsuyama, H., Yata, K., Niwa, A., Sasaki, R., Ayaki, T., Maki, T., Wakita, H. & Tomimoto, H., 21-06-2019, : : Neuroscience Letters. 704, p. 133-140 8 p.

研究成果: Article

Leptin Receptors
Astrocytes
Transgenic Mice
Up-Regulation
Phosphorylation

Classification of factors involved in nonreportable results of noninvasive prenatal testing (NIPT) and prediction of success rate of second NIPT

Suzumori, N., Sekizawa, A., Takeda, E., Samura, O., Sasaki, A., Akaishi, R., Wada, S., Hamanoue, H., Hirahara, F., Kuriki, H., Sawai, H., Nakamura, H., Yamada, T., Miura, K., Masuzaki, H., Yamashita, T., Kamei, Y., Namba, A., Murotsuki, J., Tanemoto, T. および36人Fukushima, A., Haino, K., Tairaku, S., Matsubara, K., Maeda, K., Kaji, T., Ogawa, M., Osada, H., Nishizawa, H., Okamoto, Y., Kanagawa, T., Kakigano, A., Endo, M., Kitagawa, M., Ogawa, M., Izumi, S., Katagiri, Y., Takeshita, N., Kasai, Y., Naruse, K., Neki, R., Masuyama, H., Hyodo, M., Kawano, Y., Ohba, T., Ichizuka, K., Nagamatsu, T., Watanabe, A., Nishikawa, N., Hamajima, N., Shirato, N., Yotsumoto, J., Nishiyama, M., Koide, K., Hirose, T. & Sago, H., 01-01-2019, : : Prenatal Diagnosis. 39, 2, p. 100-106 7 p.

研究成果: Article

High-Throughput Nucleotide Sequencing
DNA
Mothers
Pregnant Women
Heparin
B-Lymphoid Precursor Cells
Gene Fusion
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
CD5 Antigens

Clostridioides difficile: A potential source of NpmA in the clinical environment

Marsh, J. W., Pacey, M. P., Ezeonwuka, C., Ohm, S. L., Snyder, D., Cooper, V. S., Harrison, L. H., Doi, Y. & Mustapha, M. M., 01-02-2019, : : Journal of Antimicrobial Chemotherapy. 74, 2, p. 521-523 3 p.

研究成果: Letter

c-Met Expression Is a Useful Marker for Prognosis Prediction in IDH-Mutant Lower-Grade Gliomas and IDH-Wildtype Glioblastomas

Oba, S., Yamada, Y., Murayama, K., Sandika, E., Sasaki, H., Yamada, S., Abe, M., Hasegawa, M. & Hirose, Y., 01-01-2019, : : World Neurosurgery.

研究成果: Article

Astrocytoma
Glioblastoma
Glioma
Oligodendroglioma
Neoplasms

Co-existence of ossification of the nuchal ligament is associated with severity of ossification in the whole spine in patients with cervical ossification of the posterior longitudinal ligament -A multi-center CT study-

Yoshii, T., Hirai, T., Iwanami, A., Nagoshi, N., Takeuchi, K., Mori, K., Yamada, T., Seki, S., Tsuji, T., Fujiyoshi, K., Furukawa, M., Nishimura, S., Wada, K., Koda, M., Furuya, T., Matsuyama, Y., Hasegawa, T., Takeshita, K., Kimura, A., Abematsu, M. および15人Haro, H., Ohba, T., Watanabe, M., Katoh, H., Watanabe, K., Ozawa, H., Kanno, H., Imagama, S., Ando, K., Fujibayashi, S., Matsumoto, M., Nakamura, M., Yamazaki, M., Okawa, A. & Kawaguchi, Y., 01-01-2019, : : Journal of Orthopaedic Science. 24, 1, p. 35-41 7 p.

研究成果: Article

Ossification of Posterior Longitudinal Ligament
Ligaments
Osteogenesis
Spine
Tomography
Bipolar Disorder
Randomized Controlled Trials
Placebos
Incidence
Network Meta-Analysis
Intratracheal Intubation
Critical Illness
Cross-Over Studies
Bacterial Load
Aspiration Pneumonia
Polyribosomes
Endoplasmic Reticulum
Protein Biosynthesis
Protein Splicing
Messenger RNA
Congenic Mice
Tryptophan Hydroxylase
Serotonin
Alleles
Amino Acids