ジブカイン塩酸塩による接触皮膚炎の 2 例

Case 1 was a 66- year-old man. After he used the disinfectant“Skin Aid^R ”on a right lower leg bruise, erythema with itching developed on the same region. Patch testing was performed with the ingredients of“Skin Aid”. A positive reaction was noted for dibucaine hydrochloride. Case 2 was a 9-year-old male. After he used the disinfectant“MEMO-A ^R ”for a left knee abrasion, small blisters developed on the same region. Patch testing was performed with the ingredients of “MEMO-A ^R ”. A positive reaction was noted for dibucaine hydrochloride. Both cases were diagnosed as contact dermatitis to dibucaine hydrochloride. Dibucaine hydrochloride is an amide-type quinoline derivative, and cross-reactions with other local anesthetics do not occur. However, as there was a report of positive reactions with multiple systems of local anesthesia on patch testing, we need to use local anesthetics carefully.