TY - JOUR
T1 - 若年者の一般用医薬品による急性薬物中毒の現状
AU - Hirose, Masayuki
AU - Hirakawa, Akihiko
AU - Niwa, Wakana
AU - Higashiguchi, Takahiko
AU - Tajima, Kousuke
AU - Kato, Takahiro
AU - Yamada, Shigeki
N1 - Publisher Copyright:
© 2021 The Pharmaceutical Society of Japan
PY - 2021
Y1 - 2021
N2 - We discuss the current status of, and possible countermeasures for, acute drug poisoning among adolescents using OTC drugs. In the last 10 years, 36 patients aged < 20 years who overdosed on OTC drugs were examined for the type of drug ingested, its active ingredients in cases of lethal dose intake, and the relevant place of purchase. Patients aged < 20 years accounted for 30% of all the cases. The ingestion of multi-ingredient common-cold medication was the highest at 23%, and no ingestion of any first-class OTC drugs was observed. Caffeine accounted for 54% of the cases of lethal dose intake. At 80%, the most common method of drug purchase was from drugstores and other OTC vendors. In recent years, the number of adolescents patients who take lethal doses of OTC drugs has been increasing, and new measures are needed to avoid such cases. School pharmacists and vendors play a major role in reducing the incidences of drug poisoning. As drugs can be easily purchased over the counter, increasing the vendors' awareness of the problem throughout society may be the quickest way to reduce the incidences of acute drug poisoning among adolescents.
AB - We discuss the current status of, and possible countermeasures for, acute drug poisoning among adolescents using OTC drugs. In the last 10 years, 36 patients aged < 20 years who overdosed on OTC drugs were examined for the type of drug ingested, its active ingredients in cases of lethal dose intake, and the relevant place of purchase. Patients aged < 20 years accounted for 30% of all the cases. The ingestion of multi-ingredient common-cold medication was the highest at 23%, and no ingestion of any first-class OTC drugs was observed. Caffeine accounted for 54% of the cases of lethal dose intake. At 80%, the most common method of drug purchase was from drugstores and other OTC vendors. In recent years, the number of adolescents patients who take lethal doses of OTC drugs has been increasing, and new measures are needed to avoid such cases. School pharmacists and vendors play a major role in reducing the incidences of drug poisoning. As drugs can be easily purchased over the counter, increasing the vendors' awareness of the problem throughout society may be the quickest way to reduce the incidences of acute drug poisoning among adolescents.
UR - http://www.scopus.com/inward/record.url?scp=85121028846&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85121028846&partnerID=8YFLogxK
U2 - 10.1248/YAKUSHI.21-00147
DO - 10.1248/YAKUSHI.21-00147
M3 - 学術論文
C2 - 34853209
AN - SCOPUS:85121028846
SN - 0031-6903
VL - 141
SP - 1389
EP - 1392
JO - Yakugaku Zasshi
JF - Yakugaku Zasshi
IS - 12
ER -