TY - JOUR
T1 - 過誤腫性ポリポーシスの診断と治療
AU - Ohmiya, Naoki
AU - Nakamura, Masanao
AU - Shibata, Tomoyuki
N1 - Publisher Copyright:
© 2021 Japan Gastroenterological Endoscopy Society. All rights reserved.
PY - 2021
Y1 - 2021
N2 - The hamartomatous polyposis syndromes are a group of inherited disorders that include Peutz-Jeghers syndrome (PJS), juvenile polyposis syndrome, Cowden syndrome, and tuberous sclerosis complex (TSC). PJS, Cowden syndrome, and TSC are characterized by phenotypic manifestations, which may be a clue to their diagnosis. The most frequent complications of PJS are intussusception and chronic anemia. Earlier entire small bowel examination with capsule endoscopy and balloon-assisted enteroscopy enabling accurate diagnosis and subsequent endoscopic polyp removal obviates the need for unnecessary multiple surgeries. Patients with a hamartomatous polyposis syndrome are at an elevated risk for gastrointestinal and extragastrointestinal malignancies; therefore periodic surveillance is needed. Here, we describe the clinical features, diagnostics, and therapeutics of hamartomatous polyposis syndromes.
AB - The hamartomatous polyposis syndromes are a group of inherited disorders that include Peutz-Jeghers syndrome (PJS), juvenile polyposis syndrome, Cowden syndrome, and tuberous sclerosis complex (TSC). PJS, Cowden syndrome, and TSC are characterized by phenotypic manifestations, which may be a clue to their diagnosis. The most frequent complications of PJS are intussusception and chronic anemia. Earlier entire small bowel examination with capsule endoscopy and balloon-assisted enteroscopy enabling accurate diagnosis and subsequent endoscopic polyp removal obviates the need for unnecessary multiple surgeries. Patients with a hamartomatous polyposis syndrome are at an elevated risk for gastrointestinal and extragastrointestinal malignancies; therefore periodic surveillance is needed. Here, we describe the clinical features, diagnostics, and therapeutics of hamartomatous polyposis syndromes.
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U2 - 10.11280/gee.63.1323
DO - 10.11280/gee.63.1323
M3 - 学術論文
AN - SCOPUS:85112640828
SN - 0387-1207
VL - 63
SP - 1323
EP - 1335
JO - GASTROENTEROLOGICAL ENDOSCOPY
JF - GASTROENTEROLOGICAL ENDOSCOPY
IS - 7
ER -