1,25-Dihydroxyvitamin D-mediated hypercalcemia in ovarian dysgerminoma

Hibi Masahito, Fujio Hara, Hirokazu Tomishige, Yoshihisa Nishida, Takazumi Kato, Naotake Okumura, Takashi Hashimoto, Ryoichi Kato

研究成果: Article査読

27 被引用数 (Scopus)

抄録

Humoral hypercalcemia of malignancy (HHM) is a rare complication of malignant pediatric tumors, specifically those that secrete humoral factor(s), such as parathyroid hormone-related peptide (PTHrP). The authors report a case of severe hypercalcemia associated with ovarian dysgerminoma in a 10-year-old girl. In this case, the humoral factor was considered to be 1,25- dihydroxyvitamin D. HHM is extremely resistant to medical therapy. Therefore, tumor resection or volume reduction is necessary to control serum calcium levels.

本文言語English
ページ(範囲)73-78
ページ数6
ジャーナルPediatric Hematology and Oncology
25
1
DOI
出版ステータスPublished - 01-2008

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology

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