1,25-Dihydroxyvitamin D-mediated hypercalcemia in ovarian dysgerminoma

Hibi Masahito; Fujio Hara; Hirokazu Tomishige; Yoshihisa Nishida; Takazumi Kato; Naotake Okumura; Takashi Hashimoto; Ryoichi Kato

doi:10.1080/08880010701774033

1,25-Dihydroxyvitamin D-mediated hypercalcemia in ovarian dysgerminoma

Hibi Masahito
, Fujio Hara
, Hirokazu Tomishige
, Yoshihisa Nishida
, Takazumi Kato
, Naotake Okumura
, Takashi Hashimoto
, Ryoichi Kato

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

45 被引用数 (Scopus)

抄録

Humoral hypercalcemia of malignancy (HHM) is a rare complication of malignant pediatric tumors, specifically those that secrete humoral factor(s), such as parathyroid hormone-related peptide (PTHrP). The authors report a case of severe hypercalcemia associated with ovarian dysgerminoma in a 10-year-old girl. In this case, the humoral factor was considered to be 1,25- dihydroxyvitamin D. HHM is extremely resistant to medical therapy. Therefore, tumor resection or volume reduction is necessary to control serum calcium levels.

本文言語	英語
ページ（範囲）	73-78
ページ数	6
ジャーナル	Pediatric Hematology and Oncology
巻	25
号	1
DOI	https://doi.org/10.1080/08880010701774033
出版ステータス	出版済み - 01-2008
外部発表	はい

All Science Journal Classification (ASJC) codes

小児科学、周産期医学および子どもの健康
血液学
腫瘍学

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10.1080/08880010701774033

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abstract = "Humoral hypercalcemia of malignancy (HHM) is a rare complication of malignant pediatric tumors, specifically those that secrete humoral factor(s), such as parathyroid hormone-related peptide (PTHrP). The authors report a case of severe hypercalcemia associated with ovarian dysgerminoma in a 10-year-old girl. In this case, the humoral factor was considered to be 1,25- dihydroxyvitamin D. HHM is extremely resistant to medical therapy. Therefore, tumor resection or volume reduction is necessary to control serum calcium levels.",

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AU - Masahito, Hibi

AU - Hara, Fujio

AU - Tomishige, Hirokazu

AU - Nishida, Yoshihisa

AU - Kato, Takazumi

AU - Okumura, Naotake

AU - Hashimoto, Takashi

AU - Kato, Ryoichi

PY - 2008/1

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N2 - Humoral hypercalcemia of malignancy (HHM) is a rare complication of malignant pediatric tumors, specifically those that secrete humoral factor(s), such as parathyroid hormone-related peptide (PTHrP). The authors report a case of severe hypercalcemia associated with ovarian dysgerminoma in a 10-year-old girl. In this case, the humoral factor was considered to be 1,25- dihydroxyvitamin D. HHM is extremely resistant to medical therapy. Therefore, tumor resection or volume reduction is necessary to control serum calcium levels.

AB - Humoral hypercalcemia of malignancy (HHM) is a rare complication of malignant pediatric tumors, specifically those that secrete humoral factor(s), such as parathyroid hormone-related peptide (PTHrP). The authors report a case of severe hypercalcemia associated with ovarian dysgerminoma in a 10-year-old girl. In this case, the humoral factor was considered to be 1,25- dihydroxyvitamin D. HHM is extremely resistant to medical therapy. Therefore, tumor resection or volume reduction is necessary to control serum calcium levels.

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UR - https://www.scopus.com/pages/publications/38649139108#tab=citedBy

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JO - Pediatric Hematology and Oncology

JF - Pediatric Hematology and Oncology

IS - 1

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1,25-Dihydroxyvitamin D-mediated hypercalcemia in ovarian dysgerminoma

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