3 Tesla magnetic resonance imaging obtained 4 hours after intravenous gadolinium injection in patients with sudden deafness

Mitsuhiko Tagaya, Masaaki Teranishi, Shinji Naganawa, Tomoyuki Iwata, Tadao Yoshida, Hironao Otake, Seiichi Nakata, Michihiko Sone, Tsutomu Nakashima

研究成果: Article査読

45 被引用数 (Scopus)

抄録

Conclusion: 3 Tesla (3T) magnetic resonance imaging (MRI) performed 4 h after intravenous gadolinium (Gd) injection provides sufficient anatomic resolution of the inner ear fluid spaces in sudden deafness. The signal intensity ratio (SIR) between the cochlea and cerebellum may be a good indicator of disruption of the bloodlabyrinthine barrier. Objectives: We evaluated the inner ear 4 h after intravenous Gd injection to determine whether 3T MRI enables the acquisition of images of the affected inner ear in sudden deafness. Methods: Ten patients underwent 3T MRI scanning 4 h after intravenous Gd injection. Three-dimensional fluid-attenuated inversion recovery (3D-FLAIR) MRI was performed. Results: The SIR varied from 0.45 to 2.17 in 11 affected ears and from 0.43 to 1.48 in 9 unaffected ears. The difference of contrast (affected ear vs unaffected ear) could be detected in five of the nine patients with unilateral sudden deafness. The Gd distribution was recognized in the vestibule of 10 affected ears and in the cochlea of 5 affected ears, in which no significant hydrops was observed. In the remaining vestibules and cochleas of affected ears, the Gd enhancement was too faint to evaluate the endolymphatic hydrops.

本文言語English
ページ(範囲)665-669
ページ数5
ジャーナルActa Oto-Laryngologica
130
6
DOI
出版ステータスPublished - 06-2010
外部発表はい

All Science Journal Classification (ASJC) codes

  • 耳鼻咽喉科学

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