研究成果の検索

2019
1 引用 (Scopus)

5-HT 1A receptor agonist 8-OH-DPAT induces serotonergic behaviors in mice via interaction between PKCδ and p47phox

Tran, H. Q., Shin, E. J., Hoai Nguyen, B. C., Phan, D. H., Kang, M. J., Jang, C. G., Jeong, J. H., Nah, S. Y., Mouri, A., Saito, K., Nabeshima, T. & Kim, H. C., 01-01-2019, : : Food and Chemical Toxicology. 123, p. 125-141 17 p.

研究成果: Article

8-Hydroxy-2-(di-n-propylamino)tetralin
Receptor, Serotonin, 5-HT1A
serotonin
agonists
Serotonin

A 20-year prospective longitudinal MRI study on cervical spine after whiplash injury: Follow-up of a cross-sectional study

Daimon, K., Fujiwara, H., Nishiwaki, Y., Okada, E., Nojiri, K., Shimizu, K., Ishihama, H., Fujita, N., Ichihara, D., Tsuji, T., Nakamura, M., Matsumoto, M. & Watanabe, K., 01-07-2019, : : Journal of Orthopaedic Science. 24, 4, p. 579-583 5 p.

研究成果: Article

Whiplash Injuries
Longitudinal Studies
Spine
Neck Pain
Cross-Sectional Studies

A case of dihydropyrimidinase deficiency incidentally detected by urine metabolome analysis

Tsuchiya, H., Akiyama, T., Kuhara, T., Nakajima, Y., Ohse, M., Kurahashi, H., Kato, T., Maeda, Y., Yoshinaga, H. & Kobayashi, K., 01-03-2019, : : Brain and Development. 41, 3, p. 280-284 5 p.

研究成果: Article

Metabolome
Urine
Mutation
Fluorouracil
Metabolomics
1 引用 (Scopus)

A case of early onset life-threatening epilepsy associated with a novel ATP1A3 gene variant

Ishihara, N., Inagaki, H., Miyake, M., Kawamura, Y., Yoshikawa, T. & Kurahashi, H., 01-03-2019, : : Brain and Development. 41, 3, p. 285-291 7 p.

研究成果: Article

Epilepsy
Mutation
Genes
Respiratory Insufficiency
Parents
公開
Lymphoproliferative Disorders
Leiomyosarcoma
Kidney Transplantation
Human Herpesvirus 4
Biopsy
Signet Ring Cell Carcinoma
Human papillomavirus 16
Cervix Uteri
Genome
Neoplasms

A case of uterine lymphangioleiomyomatosis in a young woman that was identified via peritonitis

Yoshizawa, H., Kawai, S., Hirota, Y., Ueda, T., Kuroda, M. & Fujii, T., 01-02-2019, : : Journal of Obstetrics and Gynaecology Research. 45, 2, p. 482-486 5 p.

研究成果: Article

Lymphangioleiomyomatosis
Peritonitis
Tuberous Sclerosis
Ovariectomy
Hysterectomy
Cognition
Alzheimer Disease
Magnetic Resonance Imaging
Neuropsychological Tests
Atrophy

A complementary scheme for automated detection of high-uptake regions on dedicated breast PET and whole-body PET/CT

Minoura, N., Teramoto, A., Ito, A., Yamamuro, O., Nishio, M., Saito, K. & Fujita, H., 01-09-2019, : : Radiological Physics and Technology. 12, 3, p. 260-267 8 p.

研究成果: Article

breast
Breast
tomography
Tomography
Axilla

A constitutional jumping translocation involving the y and acrocentric chromosomes

Tsutsumi, M., Fujita, N., Suzuki, F., Mishima, T., Fujieda, S., Watari, M., Takahashi, N., Tonoki, H., Moriwaka, O., Endo, T. & Kurahashi, H., 01-01-2019, : : Asian Journal of Andrology. 21, 1, p. 101-103 3 p.

研究成果: Letter

Chromosomes

Acquired expression of mutant mitofusin 2 causes progressive neurodegeneration and abnormal behavior

Ishikawa, K., Yamamoto, S., Takai, S., Nishimura, N., Tani, H., Mito, T., Matsumoto, H., Miyakawa, T. & Nakada, K., 27-02-2019, : : Journal of Neuroscience. 39, 9, p. 1588-1604 17 p.

研究成果: Article

Mitochondrial Dynamics
Neurodegenerative Diseases
Neurons
Memory Disorders
Learning

Activities of daily living among elderly persons with severe aortic stenosis

Fukui, S., Kawakami, M., Otaka, Y., Ishikawa, A., Yashima, F., Hayashida, K., Muraoka, K. & Liu, M., 01-01-2019, : : Disability and Rehabilitation.

研究成果: Article

Aortic Valve Stenosis
Activities of Daily Living
Cerebrovascular Disorders
Heart Failure
Nutritional Status
AMPA Receptors
Social Behavior
Ketamine
N-Methyl-D-Aspartate Receptors
Acids

ADAMTS8 Promotes the Development of Pulmonary Arterial Hypertension and Right Ventricular Failure: A Possible Novel Therapeutic Target

Omura, J., Satoh, K., Kikuchi, N., Satoh, T., Kurosawa, R., Nogi, M., Ohtsuki, T., Al-Mamun, M. E., Siddique, M. A. H., Yaoita, N., Sunamura, S., Miyata, S., Hoshikawa, Y., Okada, Y. & Shimokawa, H., 25-10-2019, : : Circulation research. 125, 10, p. 884-906 23 p.

研究成果: Article

Pulmonary Hypertension
Smooth Muscle Myocytes
Pulmonary Artery
Therapeutics
Cell Proliferation

A decision tree-based survival analysis of patients with a history of inappropriate implantable cardioverter-defibrillator therapy

Yamamoto, M., Okajima, K., Shimane, A., Ozawa, T., Morishima, I., Asai, T., Takagi, M., Kasai, A., Fujii, E., Kiyono, K., Watanabe, E. & Ozaki, Y., 01-01-2019, : : International heart journal. 60, 2, p. 318-326 9 p.

研究成果: Article

公開
Decision Trees
Implantable Defibrillators
Survival Analysis
Decision Support Techniques
Therapeutics
8 引用 (Scopus)

Adiposity and risk of decline in glomerular filtration rate: Meta-analysis of individual participant data in a global consortium

Chang, A. R., Grams, M. E., Ballew, S. H., Bilo, H., Correa, A., Evans, M., Gutierrez, O. M., Hosseinpanah, F., Iseki, K., Kenealy, T., Klein, B., Kronenberg, F., Lee, B. J., Li, Y., Miura, K., Navaneethan, S. D., Roderick, P. J., Valdivielso, J. M., Visseren, F. L. J., Zhang, L. および6人, Gansevoort, R. T., Hallan, S. I., Levey, A. S., Matsushita, K., Shalev, V. & Woodward, M., 01-01-2019, : : BMJ (Online). 364, k5301.

研究成果: Article

Adiposity
Glomerular Filtration Rate
Meta-Analysis
Body Mass Index
Waist Circumference
Intraabdominal Infections
Colistin
Acinetobacter baumannii
Carbapenems
Bacteremia

Admission heart rate is a determinant of effectiveness of beta-blockers in acute myocardial infarction patients

on behalf of J-MINUET Investigators, 01-01-2019, : : Circulation Journal. 83, 5, p. 1054-1063 10 p.

研究成果: Article

公開
Heart Rate
Myocardial Infarction
Bradycardia
Unstable Angina
Tachycardia
1 引用 (Scopus)
Indigo Carmine
Ulcerative Colitis
Pulmonary Hypertension
Intussusception
Liver Diseases
公開
Hypogonadism
Testicular Neoplasms
Multicenter Studies
Drug Therapy
Survivors
1 引用 (Scopus)

A genome-wide association study of coping behaviors suggests FBXO45 is associated with emotional expression

Shimanoe, C., Hachiya, T., Hara, M., Nishida, Y., Tanaka, K., Sutoh, Y., Shimizu, A., Hishida, A., Kawai, S., Okada, R., Tamura, T., Matsuo, K., Ito, H., Ozaki, E., Matsui, D., Ibusuki, R., Shimoshikiryo, I., Takashima, N., Kadota, A., Arisawa, K. および12人, Uemura, H., Suzuki, S., Watanabe, M., Kuriki, K., Endoh, K., Mikami, H., Nakamura, Y., Momozawa, Y., Kubo, M., Nakatochi, M., Naito, M. & Wakai, K., 01-02-2019, : : Genes, Brain and Behavior. 18, 2, e12481.

研究成果: Article

Genome-Wide Association Study
Psychological Adaptation
Genes
Regulator Genes
Synapses
公開
Inbred C57BL Mouse
Locomotion
Fear
Startle Reflex
Anxiety

Alteration of specific cytokine expression patterns in patients with breast cancer

Kawaguchi, K., Sakurai, M., Yamamoto, Y., Suzuki, E., Tsuda, M., Kataoka, T. R., Hirata, M., Nishie, M., Nojiri, T., Kumazoe, M., Saito, K. & Toi, M., 01-12-2019, : : Scientific reports. 9, 1, 2924.

研究成果: Article

公開
Breast Neoplasms
Cytokines
Healthy Volunteers
Interleukin-1
Interleukin-9
1 引用 (Scopus)

Altered regulation of serum lysosomal acid hydrolase activities in Parkinson's disease: A potential peripheral biomarker?

Niimi, Y., Ito, S., Mizutani, Y., Murate, K., Shima, S., Ueda, A., Satake, W., Hattori, N., Toda, T. & Mutoh, T., 01-04-2019, : : Parkinsonism and Related Disorders. 61, p. 132-137 6 p.

研究成果: Article

Galactosidases
Hydrolases
Parkinson Disease
Parkinsonian Disorders
Biomarkers
Textbooks
Information use
Lung
Education
Students
公開
Ascites
Albumins
Therapeutics
Serum Albumin
Paracentesis

Amplified association between blood pressure and albuminuria in overweight patients with biopsy-proven hypertensive nephrosclerosis

Research Group of Diabetic Nephropathy and Nephrosclerosis, Ministry of Health, Labour and Welfare of Japan & Japan Agency for Medical Research and Development, 01-01-2019, : : American Journal of Hypertension. 32, 5, p. 486-491 6 p.

研究成果: Article

Nephrosclerosis
Albuminuria
Blood Pressure
Biopsy
Glomerular Filtration Rate

A multicenter, open-label, single-arm study of anamorelin (ONO-7643) in advanced gastrointestinal cancer patients with cancer cachexia

Hamauchi, S., Furuse, J., Takano, T., Munemoto, Y., Furuya, K., Baba, H., Takeuchi, M., Choda, Y., Higashiguchi, T., Naito, T., Muro, K., Takayama, K., Oyama, S., Takiguchi, T., Komura, N. & Tamura, K., 01-01-2019, (Accepted/In press) : : Cancer.

研究成果: Article

公開
Cachexia
Gastrointestinal Neoplasms
Neoplasms
Appetite
Body Weight

A multicenter trial of extracorporeal cardiac shock wave therapy for refractory angina pectoris: report of the highly advanced medical treatment in Japan

Kikuchi, Y., Ito, K., Shindo, T., Hao, K., Shiroto, T., Matsumoto, Y., Takahashi, J., Matsubara, T., Yamada, A., Ozaki, Y., Hiroe, M., Misumi, K., Ota, H., Takanami, K., Hiraide, T., Takase, K., Tanji, F., Tomata, Y., Tsuji, I. & Shimokawa, H., 22-01-2019, : : Heart and Vessels. 34, 1, p. 104-113 10 p.

研究成果: Article

Convulsive Therapy
Angina Pectoris
Multicenter Studies
Japan
Heart Ventricles

Analysis of multiscale entropy characteristics of heart rate variability in patients with permanent atrial fibrillation for predicting ischemic stroke risk

Matsuoka, R., Yoshino, K., Watanabe, E. & Kiyono, K., 21-01-2019, Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018. Schmidt, H., Griol, D., Wang, H., Baumbach, J., Zheng, H., Callejas, Z., Hu, X., Dickerson, J. & Zhang, L. (版). Institute of Electrical and Electronics Engineers Inc., 1 p. 8621178. (Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018).

研究成果: Conference contribution

Entropy
Atrial Fibrillation
Heart Rate
Stroke
Probability density function

Anaphylaxis to xylitol diagnosed by skin prick test and basophil activation test

Okamoto, K., Kagami, M., Kawai, M., Mori, Y., Yamawaki, K., Nakajima, Y., Kondo, Y. & Tsuge, I., 01-2019, : : Allergology International. 68, 1, p. 130-131 2 p.

研究成果: Letter

Xylitol
Basophils
Anaphylaxis
Skin Tests

Anastrozole Aromatase Inhibitor Plasma Drug Concentration Genome-Wide Association Study: Functional Epistatic Interaction Between SLC38A7 and ALPPL2

Dudenkov, T. M., Liu, D., Cairns, J., Devarajan, S., Zhuang, Y., Ingle, J. N., Buzdar, A. U., Robson, M. E., Kubo, M., Batzler, A., Barman, P., Jenkins, G. D., Carlson, E. E., Goetz, M. P., Northfelt, D. W., Moreno-Aspitia, A., Desta, Z., Reid, J. M., Kalari, K. R., Wang, L. および1人, Weinshilboum, R. M., 01-07-2019, : : Clinical Pharmacology and Therapeutics. 106, 1, p. 219-227 9 p.

研究成果: Article

公開
Aromatase Inhibitors
Genome-Wide Association Study
Single Nucleotide Polymorphism
Pharmaceutical Preparations
Breast Neoplasms
4 引用 (Scopus)
Major Histocompatibility Complex
Vertebrates
Peptides
Amphibians
Zebrafish

An effective and promising treatment with adalimumab for impetigo herpetiformis with postpartum flare-up

Yamashita, T., Hamada, T., Maruta, Y., Kajita, A., Hirai, Y., Morizane, S., Watanabe, S., Sugiura, K. & Iwatsuki, K., 01-03-2019, : : International Journal of Dermatology. 58, 3, p. 350-353 4 p.

研究成果: Article

Impetigo
Postpartum Period
Adalimumab

An epilepsy-associated glioneuronal tumor with mixed morphology harboring FGFR1 mutation

Yamada, S., Nobusawa, S., Yamazaki, T., Teranishi, T., Watanabe, S., Murayama, K., Ohba, S., Okabe, A., Sakurai, K., Urano, M., Tsukamoto, T., Yokoo, H., Hirose, Y. & Abe, M., 01-01-2019, : : Pathology International. 69, 6, p. 372-377 6 p.

研究成果: Article

Epilepsy
Mutation
Oligodendroglia
Neoplasms
Neuroepithelial Neoplasms

An initial genetic analysis of gemcitabine-induced high-grade neutropenia in pancreatic cancer patients in CALGB 80303 (Alliance)

Innocenti, F., Jiang, C., Sibley, A. B., Denning, S., Etheridge, A. S., Watson, D., Niedzwiecki, D., Hatch, A. J., Hurwitz, H. I., Nixon, A. B., Furukawa, Y., Kubo, M., Crona, D. J., Kindler, H. L., McLeod, H. L., Ratain, M. J. & Owzar, K., 01-08-2019, : : Pharmacogenetics and Genomics. 29, 6, p. 123-131 9 p.

研究成果: Article

gemcitabine
Neutropenia
Pancreatic Neoplasms
Genome
Confidence Intervals

A novel intragenic deletion in OPHN1 in a Japanese patient with Dandy-Walker malformation

Iida, A., Takeshita, E., Kosugi, S., Kamatani, Y., Momozawa, Y., Kubo, M., Nakagawa, E., Kurosawa, K., Inoue, K. & Goto, Y. I., 01-12-2019, : : Human Genome Variation. 6, 1, 1.

研究成果: Article

公開
Dandy-Walker Syndrome
Exons
Fourth Ventricle
Intellectual Disability
Dilatation
2 引用 (Scopus)

Antimicrobial treatment challenges in the era of carbapenem resistance

Peri, A. M., Doi, Y., Potoski, B. A., Harris, P. N. A., Paterson, D. L. & Righi, E., 08-2019, : : Diagnostic Microbiology and Infectious Disease. 94, 4, p. 413-425 13 p.

研究成果: Review article

Carbapenems
Anti-Bacterial Agents
Enterobacteriaceae Infections
Colistin
Aminoglycosides

A patient with bullous pemphigoid with mucosal involvement serologically positive for anti-BP230 autoantibodies only

Taki, T., Takeichi, T., Kono, M., Sugiura, K., Sugimura, Y., Ishii, N., Hashimoto, T. & Akiyama, M., 01-01-2019, (Accepted/In press) : : British Journal of Dermatology.

研究成果: Letter

Bullous Pemphigoid
Autoantibodies
3 引用 (Scopus)

A Pharmacogenetic Prediction Model of Progression-Free Survival in Breast Cancer using Genome-Wide Genotyping Data from CALGB 40502 (Alliance)

Rashkin, S. R., Chua, K. C., Ho, C., Mulkey, F., Jiang, C., Mushiroda, T., Kubo, M., Friedman, P. N., Rugo, H. S., McLeod, H. L., Ratain, M. J., Castillos, F., Naughton, M., Overmoyer, B., Toppmeyer, D., Witte, J. S., Owzar, K. & Kroetz, D. L., 01-03-2019, : : Clinical Pharmacology and Therapeutics. 105, 3, p. 738-745 8 p.

研究成果: Article

Pharmacogenetics
Disease-Free Survival
Area Under Curve
Genome
Breast Neoplasms
Artificial Intelligence
Radiology
Technology
Research
Lung Neoplasms
2 引用 (Scopus)

A Primer on AmpC β-Lactamases: Necessary Knowledge for an Increasingly Multidrug-resistant World

Tamma, P. D., Doi, Y., Bonomo, R. A., Johnson, J. K. & Simner, P. J., 27-09-2019, : : Clinical Infectious Diseases. 69, 8, p. 1446-1455 10 p.

研究成果: Review article

Lactams
Enterobacteriaceae
Enterobacter cloacae
Selection Bias
Cephalosporins

A Prospective Study Evaluating the Clinical Utility of the Tag-Less Patency Capsule with Extended Time for Confirming Functional Patency

Watanabe, K., Omiya, N., Nakamura, M. & Fujiwara, Y., 01-01-2019, (Accepted/In press) : : Digestion.

研究成果: Article

Capsules
Prospective Studies
Capsule Endoscopy
Information Services
Pathologic Constriction
2 引用 (Scopus)

A prospective study of acinetobacter baumannii complex isolates and colistin susceptibility monitoring by mass spectrometry of microbial membrane glycolipids

Leung, L. M., McElheny, C. L., Gardner, F. M., Chandler, C. E., Bowler, S. L., Mettus, R. T., Spychala, C. N., Fowler, E. L., Opene, B. N. A., Myers, R. A., Goodlett, D. R., Doi, Y. & Ernst, R. K., 01-03-2019, : : Journal of clinical microbiology. 57, 3, e01100-18.

研究成果: Article

Colistin
Acinetobacter baumannii
Glycolipids
Mass Spectrometry
Prospective Studies

A randomized phase II study of nutritional and exercise treatment for elderly patients with advanced non-small cell lung or pancreatic cancer: The NEXTAC-TWO study protocol

Miura, S., Naito, T., Mitsunaga, S., Omae, K., Mori, K., Inano, T., Yamaguchi, T., Tatematsu, N., Okayama, T., Morikawa, A., Mouri, T., Tanaka, H., Kimura, M., Imai, H., Mizukami, T., Imoto, A., Kondoh, C., Shiotsu, S., Okuyama, H., Ueno, M. および6人, Takahashi, T., Tsuji, T., Aragane, H., Inui, A., Higashiguchi, T. & Takayama, K., 31-05-2019, : : BMC Cancer. 19, 1, 528.

研究成果: Article

公開
Pancreatic Neoplasms
Non-Small Cell Lung Carcinoma
Exercise
Neoplasms
Cachexia

Artificial intelligence predicts the progression of diabetic kidney disease using big data machine learning

Makino, M., Yoshimoto, R., Ono, M., Itoko, T., Katsuki, T., Koseki, A., Kudo, M., Haida, K., Kuroda, J., Yanagiya, R., Saito, E., Hoshinaga, K., Yuzawa, Y. & Suzuki, A., 01-12-2019, : : Scientific reports. 9, 1, 11862.

研究成果: Article

公開
Artificial Intelligence
Diabetic Nephropathies
Renal Dialysis
Natural Language Processing
Electronic Health Records

A single-nucleotide polymorphism influences brain morphology in drug-näve patients with major depressive disorder

Katsuki, A., Kakeda, S., Watanabe, K., Igata, R., Otsuka, Y., Kishi, T., Nguyen, L. H., Ueda, I., Iwata, N., Korogi, Y. & Yoshimura, R., 01-01-2019, : : Neuropsychiatric Disease and Treatment. 15, p. 2425-2432 8 p.

研究成果: Article

公開
Major Depressive Disorder
Single Nucleotide Polymorphism
Brain
Pharmaceutical Preparations
Genotype

Assessment of factors associated with mizoribine responsiveness in children with steroid-dependent nephrotic syndrome

Kondoh, T., Ikezumi, Y., Yokoi, K., Nakajima, Y., Matsumoto, Y., Kaneko, M., Hasegawa, H., Yamada, T., Kumagai, N., Ito, T. & Yoshikawa, T., 01-09-2019, : : Clinical and Experimental Nephrology. 23, 9, p. 1154-1160 7 p.

研究成果: Article

Nephrotic Syndrome
Steroids
Body Weight
Immunosuppressive Agents
bredinin
Frail Elderly
Mastication
Nursing Homes
Diet
Food
1 引用 (Scopus)

Association between Genetic Risk and Development of Type 2 Diabetes in a General Japanese Population: The Hisayama Study

Inaishi, J., Hirakawa, Y., Horikoshi, M., Akiyama, M., Higashioka, M., Yoshinari, M., Hata, J., Mukai, N., Kamatani, Y., Momozawa, Y., Kubo, M. & Ninomiya, T., 19-06-2019, : : Journal of Clinical Endocrinology and Metabolism. 104, 8, p. 3213-3222 10 p.

研究成果: Article

Medical problems
Type 2 Diabetes Mellitus
Population
Hazards
Precision Medicine