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• Genetic polymorphism in the phenobarbital-responsive enhancer module of the UDP-glucuronosyltransferase 1A1 gene and irinotecan toxicity

  Kitagawa, C., Ando, M., Ando, Y., Sekido, Y., Wakai, K., Imaizumi, K., Shimokata, K. & Hasegawa, Y., 01-2005, In: Pharmacogenetics and genomics. 15, 1, p. 35-41 7 p.

  研究成果: Article › 査読

  • UGT1A1 enzyme
  • Irinotecan
  • Phenobarbital
  • Genetic Polymorphisms
  • Homozygote
  59 被引用数 (Scopus)

• Genetic polymorphism of interleukin-17A and -17F genes in gastric carcinogenesis

  Shibata, T., Tahara, T., Hirata, I. & Arisawa, T., 01-07-2009, In: Human Immunology. 70, 7, p. 547-551 5 p.

  研究成果: Article › 査読

  • Interleukin-17
  • Genetic Polymorphisms
  • Carcinogenesis
  • Stomach
  • Stomach Neoplasms
  117 被引用数 (Scopus)

• Genetic polymorphism of pri-microRNA 325, targeting SLC6A4 3′-UTR, is closely associated with the risk of functional dyspepsia in Japan

  Arisawa, T., Tahara, T., Fukuyama, T., Hayashi, R., Matsunaga, K., Hayashi, N., Nakamura, M., Toshikuni, N., Shiroeda, H. & Shibata, T., 01-10-2012, In: Journal of Gastroenterology. 47, 10, p. 1091-1098 8 p.

  研究成果: Article › 査読

  • 5' Untranslated Regions
  • Dyspepsia
  • Genetic Polymorphisms
  • 3' Untranslated Regions
  • MicroRNAs
  14 被引用数 (Scopus)

• Genetic polymorphisms in organic cation transporter 1 (OCT1) in Chinese and Japanese populations exhibit altered function

  Chen, L., Takizawa, M., Chen, E., Schlessinger, A., Segenthelar, J., Choi, J. H., Sali, A., Kubo, M., Nakamura, S., Iwamoto, Y., Iwasaki, N. & Giacomini, K. M., 10-2010, In: Journal of Pharmacology and Experimental Therapeutics. 335, 1, p. 42-50 9 p.

  研究成果: Article › 査読

  • Organic Cation Transporter 1
  • Genetic Polymorphisms
  • Metformin
  • Population
  • Green Fluorescent Proteins
  56 被引用数 (Scopus)

• Genetic polymorphisms in the 5-hydroxytryptamine type 3B receptor gene and paroxetine-induced nausea

  Tanaka, M., Kobayashi, D., Murakami, Y., Ozaki, N., Suzuki, T., Iwata, N., Haraguchi, K., Ieiri, I., Kinukawa, N., Hosoi, M., Ohtani, H., Sawada, Y. & Mine, K., 03-2008, In: International Journal of Neuropsychopharmacology. 11, 2, p. 261-267 7 p.

  研究成果: Article › 査読

  • Paroxetine
  • Serotonin Receptors
  • Genetic Polymorphisms
  • Nausea
  • Genes
  52 被引用数 (Scopus)

• Genetic polymorphisms in the long noncoding RNA MIR2052HG offer a pharmacogenomic basis for the response of breast cancer patients to aromatase inhibitor therapy

  Ingle, J. N., Xie, F., Ellis, M. J., Goss, P. E., Shepherd, L. E., Chapman, J. A. W., Chen, B. E., Kubo, M., Furukawa, Y., Momozawa, Y., Stearns, V., Pritchard, K. I., Barman, P., Carlson, E. E., Goetz, M. P., Weinshilboum, R. M., Kalari, K. R. & Wang, L., 01-12-2016, In: Cancer Research. 76, 23, p. 7012-7023 12 p.

  研究成果: Article › 査読

  • Aromatase Inhibitors
  • Long Noncoding RNA
  • Pharmacogenetics
  • Genetic Polymorphisms
  • Estrogen Receptors
  27 被引用数 (Scopus)

• Genetic polymorphisms in the promoter of the interferon gamma receptor 1 gene are associated with atopic cataracts

  Matsuda, A., Ebihara, N., Kumagai, N., Fukuda, K., Ebe, K., Hirano, K., Sotozono, C., Tei, M., Hasegawa, K., Shimizu, M., Tamari, M., Namba, K., Ohno, S., Mizuki, N., Ikezawa, Z., Shirakawa, T., Hamuro, J. & Kinoshita, S., 02-2007, In: Investigative Ophthalmology and Visual Science. 48, 2, p. 583-589 7 p.

  研究成果: Article › 査読

  Open Access

  • interferon gamma receptor
  • Genetic Polymorphisms
  • Atopic Dermatitis
  • Cataract
  • Eye
  18 被引用数 (Scopus)

• Genetic polymorphisms of CD14 and Toll-like receptor-2 (TLR2) in patients with ulcerative colitis

  Wang, F., Tahara, T., Arisawa, T., Shibata, T., Nakamura, M., Fujita, H., Iwata, M., Kamiya, Y., Nagasaka, M., Takahama, K., Watanabe, M., Hirata, I. & Nakano, H., 06-2007, In: Journal of Gastroenterology and Hepatology (Australia). 22, 6, p. 925-929 5 p.

  研究成果: Article › 査読

  • Toll-Like Receptor 2
  • Genetic Polymorphisms
  • Ulcerative Colitis
  • Colitis
  • Steroids
  24 被引用数 (Scopus)

• Genetic polymorphisms of cyclooxygenase-1 (COX-1) are associated with functional dyspepsia in Japanese women

  Arisawa, T., Tahara, T., Shibata, T., Nagasaka, M., Nakamura, M., Kamiya, Y., Fujita, H., Yoshioka, D., Arima, Y., Okubo, M., Hirata, I. & Nakano, H., 01-07-2008, In: Journal of Women's Health. 17, 6, p. 1039-1043 5 p.

  研究成果: Article › 査読

  • Cyclooxygenase 1
  • Dyspepsia
  • Genetic Polymorphisms
  • Prostaglandins
  • Genes
  24 被引用数 (Scopus)

• Genetic polymorphisms of IL17A and pri-microRNA-938, targeting IL17A 3'-UTR, influence susceptibility to gastric cancer

  Arisawa, T., Tahara, T., Shiroeda, H., Matsue, Y., Minato, T., Nomura, T., Yamada, H., Hayashi, R., Saito, T., Matsunaga, K., Fukuyama, T., Hayashi, N., Otsuka, T., Fukumura, A., Nakamura, M. & Shibata, T., 01-07-2012, In: Human Immunology. 73, 7, p. 747-752 6 p.

  研究成果: Article › 査読

  • Genetic Polymorphisms
  • 3' Untranslated Regions
  • Stomach Neoplasms
  • MicroRNAs
  • Single-Stranded Conformational Polymorphism
  61 被引用数 (Scopus)

• Genetic polymorphisms of MAFK, encoding a small Maf protein, are associated with susceptibility to ulcerative colitis in Japan

  Arisawa, T., Nakamura, M., Otsuka, T., Jing, W., Sakurai, N., Takano, H., Hayashi, T., Ota, M., Nomura, T., Hayashi, R., Shimasaki, T., Tahara, T. & Shibata, T., 07-08-2017, In: World Journal of Gastroenterology. 23, 29, p. 5364-5370 7 p.

  研究成果: Article › 査読

  • Maf Transcription Factors
  • protein K
  • Genetic Polymorphisms
  • Ulcerative Colitis
  • Japan
  1 被引用数 (Scopus)

• Genetic polymorphisms of molecules associated with inflammation and immune response in Japanese subjects with functional dyspepsia

  Arisawa, T., Tahara, T., Shibata, T., Nagasaka, M., Nakamura, M., Kamiya, Y., Fujita, H., Yoshioka, D., Arima, Y., Okubo, M., Hirata, I. & Nakano, H., 01-11-2007, In: International Journal of Molecular Medicine. 20, 5, p. 717-723 7 p.

  研究成果: Article › 査読

  • Dyspepsia
  • Interleukin-17
  • Genetic Polymorphisms
  • Inflammation
  • Helicobacter pylori
  50 被引用数 (Scopus)

• Genetic polymorphisms of molecules associated with innate immune responses, TRL2 and MBL2 genes in Japanese subjects with functional dyspepsia

  Tahara, T., Shibata, T., Wang, F., Yamashita, H., Hirata, I. & Arisawa, T., 11-2010, In: Journal of Clinical Biochemistry and Nutrition. 47, 3, p. 217-223 7 p.

  研究成果: Article › 査読

  • Toll-Like Receptor 2
  • Polymorphism
  • Dyspepsia
  • Genetic Polymorphisms
  • Molecules
  16 被引用数 (Scopus)

• Genetic polymorphisms of SCN10A are associated with functional dyspepsia in Japanese subjects

  Arisawa, T., Tahara, T., Shiroeda, H., Minato, T., Matsue, Y., Saito, T., Fukuyama, T., Otsuka, T., Fukumura, A., Nakamura, M. & Shibata, T., 01-01-2013, In: Journal of Gastroenterology. 48, 1, p. 73-80 8 p.

  研究成果: Article › 査読

  • Dyspepsia
  • Genetic Polymorphisms
  • Unmyelinated Nerve Fibers
  • Homozygote
  • Alleles
  21 被引用数 (Scopus)

• Genetic polymorphisms of the adenosine triphosphate-binding cassette transporters (abcg2, abcb1) and gefitinib toxicity

  Tamura, M., Kondo, M., Horio, M., Ando, M., Saito, H., Yamamoto, M., Horio, Y. & Hasegawa, Y., 01-12-2012, In: Nagoya journal of medical science. 74, 1-2, p. 133-140 8 p.

  研究成果: Article › 査読

  • Gefitinib
  • Genetic Polymorphisms
  • Adenosine Triphosphate
  • Exanthema
  • Alleles
  32 被引用数 (Scopus)

• Genetic predictors associated with improvement of asthma symptoms in response to inhaled corticosteroids

  Park, H. W., Dahlin, A., Tse, S., Duan, Q. L., Schuemann, B., Martinez, F. D., Peters, S. P., Szefler, S. J., Lima, J. J., Kubo, M., Tamari, M. & Tantisira, K. G., 03-2014, In: Journal of Allergy and Clinical Immunology. 133, 3, p. 664-669.e5

  研究成果: Article › 査読

  • Adrenal Cortex Hormones
  • Asthma
  • Genome-Wide Association Study
  • Single Nucleotide Polymorphism
  • European Continental Ancestry Group
  51 被引用数 (Scopus)

• Genetic Predisposition to Ischemic Stroke: A Polygenic Risk Score

  Hachiya, T., Kamatani, Y., Takahashi, A., Hata, J., Furukawa, R., Shiwa, Y., Yamaji, T., Hara, M., Tanno, K., Ohmomo, H., Ono, K., Takashima, N., Matsuda, K., Wakai, K., Sawada, N., Iwasaki, M., Yamagishi, K., Ago, T., Ninomiya, T., Fukushima, A. & 21 others, Hozawa, A., Minegishi, N., Satoh, M., Endo, R., Sasaki, M., Sakata, K., Kobayashi, S., Ogasawara, K., Nakamura, M., Hitomi, J., Kita, Y., Tanaka, K., Iso, H., Kitazono, T., Kubo, M., Tanaka, H., Tsugane, S., Kiyohara, Y., Yamamoto, M., Sobue, K. & Shimizu, A., 01-02-2017, In: Stroke. 48, 2, p. 253-258 6 p.

  研究成果: Article › 査読

  • Genetic Predisposition to Disease
  • Stroke
  • Datasets
  • Confidence Intervals
  • Risk Management
  33 被引用数 (Scopus)

• Genetic profiles of fluoroquinolone-resistant Escherichia coli isolates obtained from patients with cystitis: Phylogeny, virulence factors, PAIusp subtypes, and mutation patterns

  Takahashi, A., Muratani, T., Yasuda, M., Takahashi, S., Monden, K., Ishikawa, K., Kiyota, H., Arakawa, S., Matsumoto, T., Shima, H., Kurazono, H. & Yamamoto, S., 03-2009, In: Journal of clinical microbiology. 47, 3, p. 791-795 5 p.

  研究成果: Article › 査読

  Open Access

  • Genetic Profile
  • Cystitis
  • Fluoroquinolones
  • Virulence Factors
  • Escherichia coli
  28 被引用数 (Scopus)

• Genetic regulation of slowly progressing mild muscle atrophy in fast- twitch muscles of BUF/Mna rats

  Amo, H., Saito, M., Nagao, S., Yagiu, S., Takahashi, H., Morita, H., Morita, T. M. & Matsuyama, M., 1997, In: Muscle and Nerve. 20, 10, p. 1258-1263 6 p.

  研究成果: Article › 査読

  • Inbred BUF Rats
  • Muscular Atrophy
  • Muscles
  • Dominant Genes
  • Oculomotor Muscles
  6 被引用数 (Scopus)

• Genetic risk factors of ischemic stroke identified by a genome-wide association study

  Kubo, M., 01-11-2008, In: Brain and Nerve. 60, 11, p. 1339-1346 8 p.

  研究成果: Article › 査読

  • Genome-Wide Association Study
  • Stroke
  • protein kinase C eta
  • Single Nucleotide Polymorphism
  • Genes
  6 被引用数 (Scopus)

• Genetic risk for coronary artery disease in individuals with or without type 2 diabetes

  Yamada, Y., Ichihara, S., Izawa, H., Tanaka, M. & Yokota, M., 04-2004, In: Molecular Genetics and Metabolism. 81, 4, p. 282-290 9 p.

  研究成果: Article › 査読

  • Medical problems
  • Genes
  • Coronary Artery Disease
  • Type 2 Diabetes Mellitus
  • Polymorphism
  33 被引用数 (Scopus)

• Genetic risk for restenosis after coronary balloon angioplasty

  Horibe, H., Yamada, Y., Ichihara, S., Watarai, M., Yanase, M., Takemoto, K., Shimizu, S., Izawa, H., Takatsu, F. & Yokota, M., 05-2004, In: Atherosclerosis. 174, 1, p. 181-187 7 p.

  研究成果: Article › 査読

  • Coronary Balloon Angioplasty
  • Balloon Angioplasty
  • Genes
  • Coronary Vessels
  • NADH oxidase
  16 被引用数 (Scopus)

• Genetic risk score based on the prevalence of vertebral fracture in Japanese women with osteoporosis

  Zhou, H., Mori, S., Ishizaki, T., Takahashi, A., Matsuda, K., Koretsune, Y., Minami, S., Higashiyama, M., Imai, S., Yoshimori, K., Doita, M., Yamada, A., Nagayama, S., Kaneko, K., Asai, S., Shiono, M., Kubo, M. & Ito, H., 01-12-2016, In: Bone Reports. 5, p. 168-172 5 p.

  研究成果: Article › 査読

  • Osteoporosis
  • Single Nucleotide Polymorphism
  • Alleles
  • Confidence Intervals
  • Genetic Models
  6 被引用数 (Scopus)

• Genetic risk variants of schizophrenia associated with left superior temporal gyrus volume

  Ohi, K., Hashimoto, R., Ikeda, M., Yamashita, F., Fukunaga, M., Nemoto, K., Ohnishi, T., Yamamori, H., Yasuda, Y., Fujimoto, M., Umeda-Yano, S., Watanabe, Y., Iwata, N., Weinberger, D. R. & Takeda, M., 09-2014, In: Cortex. 58, p. 23-26 4 p.

  研究成果: Letter › 査読
  14 被引用数 (Scopus)

• Genetics and reverse genetics of rotavirus

  Taniguchi, K. & Komoto, S., 08-2012, In: Current Opinion in Virology. 2, 4, p. 399-407 9 p.

  研究成果: Review article › 査読

  • Reverse Genetics
  • Rotavirus
  • Helper Viruses
  • Reoviridae
  • Genome
  13 被引用数 (Scopus)

• Genetic shifts in methicillin-resistant Staphylococcus aureus epidemic clones and toxin gene profiles in Japan: Comparative analysis among pre-epidemic, epidemic and post-epidemic phases

  Osaka, S., Okuzumi, K., Koide, S., Tamai, K., Sato, T., Tanimoto, K., Tomita, H., Suzuki, M., Nagano, Y., Shibayama, K., Arakawa, Y. & Nagano, N., 03-2018, In: Journal of Medical Microbiology. 67, 3, p. 392-399 8 p., 000687.

  研究成果: Article › 査読

  Open Access

  • Methicillin-Resistant Staphylococcus aureus
  • Epidemics
  • Japan
  • Clone Cells
  • Genes
  5 被引用数 (Scopus)

• Genetics of rheumatoid arthritis contributes to biology and drug discovery

  Okada, Y., Wu, D., Trynka, G., Raj, T., Terao, C., Ikari, K., Kochi, Y., Ohmura, K., Suzuki, A., Yoshida, S., Graham, R. R., Manoharan, A., Ortmann, W., Bhangale, T., Denny, J. C., Carroll, R. J., Eyler, A. E., Greenberg, J. D., Kremer, J. M., Pappas, D. A. & 75 others, Jiang, L., Yin, J., Ye, L., Su, D. F., Yang, J., Xie, G., Keystone, E., Westra, H. J., Esko, T., Metspalu, A., Zhou, X., Gupta, N., Mirel, D., Stahl, E. A., Diogo, D., Cui, J., Liao, K., Guo, M. H., Myouzen, K., Kawaguchi, T., Coenen, M. J. H., Van Riel, P. L. C. M., Van De Laar, M. A. F. J., Guchelaar, H. J., Huizinga, T. W. J., Dieudé, P., Mariette, X., Bridges, S. L., Zhernakova, A., Toes, R. E. M., Tak, P. P., Miceli-Richard, C., Bang, S. Y., Lee, H. S., Martin, J., Gonzalez-Gay, M. A., Rodriguez-Rodriguez, L., Rantapää-Dahlqvist, S., Ärlestig, L., Choi, H. K., Kamatani, Y., Galan, P., Lathrop, M., Eyre, S., Bowes, J., Barton, A., De Vries, N., Moreland, L. W., Criswell, L. A., Karlson, E. W., Taniguchi, A., Yamada, R., Kubo, M., Liu, J. S., Bae, S. C., Worthington, J., Padyukov, L., Klareskog, L., Gregersen, P. K., Raychaudhuri, S., Stranger, B. E., De Jager, P. L., Franke, L., Visscher, P. M., Brown, M. A., Yamanaka, H., Mimori, T., Takahashi, A., Xu, H., Behrens, T. W., Siminovitch, K. A., Momohara, S., Matsuda, F., Yamamoto, K. & Plenge, R. M., 2014, In: Nature. 506, 7488, p. 376-381 6 p.

  研究成果: Article › 査読

  • Drug Discovery
  • Rheumatoid Arthritis
  • Quantitative Trait Loci
  • Multifactorial Inheritance
  • Human Genetics
  1040 被引用数 (Scopus)

• Genetic Spectrum of EYS-associated Retinal Disease in a Large Japanese Cohort: Identification of Disease-associated Variants with Relatively High Allele Frequency

  JEGC study group, 01-12-2020, In: Scientific reports. 10, 1, 5497.

  研究成果: Article › 査読

  Open Access

  • Retinal Diseases
  • Gene Frequency
  • Cone-Rod Dystrophies
  • Leber Congenital Amaurosis
  • Whole Exome Sequencing
  3 被引用数 (Scopus)

• Genetic studies of body mass index yield new insights for obesity biology

  Lifelines Cohort Study & ADIPOGen Consortium; AGEN-BMI Working Group; CARDIOGRAMplusC4D Consortium; CKDGen Consortium; GLGC; ICBP; MAGIC Investigators; MuTHER Consortium; MIGen Consortium; PAGE Consortium; ReproGen Consortium; GENIE Consortium; International Endogene Consortium, 12-02-2015, In: Nature. 518, 7538, p. 197-206 10 p.

  研究成果: Article › 査読

  • Body Mass Index
  • Obesity
  • Adipogenesis
  • Genome-Wide Association Study
  • Adiposity
  1828 被引用数 (Scopus)

• Genetic studies on substance dependence

  Ujiie, H., Inada, T., Harano, M., Komiyayama, T., Yamada, M., Sekine, Y., Sora, I., Iwata, N., Iyo, M. & Ozaki, N., 01-12-2004, In: Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica. 106, 12, p. 1598-1603 6 p.

  研究成果: Review article › 査読
  3 被引用数 (Scopus)

• Genetic tests in clinical testing

  Takeda, M. & Funato, T., 10-12-2008, In: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine. 97, 12, p. 2920-2926 7 p.

  研究成果: Article › 査読

  Open Access

• Genetic variant of prodynorphin gene is risk factor for methamphetamine dependence

  Nomura, A., Ujike, H., Tanaka, Y., Otani, K., Morita, Y., Kishimoto, M., Morio, A., Harano, M., Inada, T., Yamada, M., Komiyama, T., Sekine, Y., Iwata, N., Sora, I., Iyo, M., Ozaki, N. & Kuroda, S., 29-05-2006, In: Neuroscience Letters. 400, 1-2, p. 158-162 5 p.

  研究成果: Article › 査読

  • preproenkephalin
  • Methamphetamine
  • Genes
  • Alleles
  • Substance-Related Disorders
  22 被引用数 (Scopus)

• Genetic variant of the p22PH0X component of NADPH oxidase C242T and the incidence of gastric cancer in Japan

  Tahara, T., Arisawa, T., Shibata, T., Nakamura, M., Wang, F., Yoshioka, D., Okubo, M., Maruyama, N., Kamano, T., Kamiya, Y., Nakamura, M., Fujita, H., Nagasaka, M., Iwata, M., Takahama, K., Watanabe, M., Yamashita, H., Nakano, H. & Hirata, I., 11-2008, In: Hepato-gastroenterology. 55, 88, p. 2273-2276 4 p.

  研究成果: Article › 査読

  • NADPH Oxidases
  • Stomach Neoplasms
  • Japan
  • Incidence
  • Genotype
  1 被引用数 (Scopus)

• Genetic variants associated with angiotensin-converting enzyme inhibitor-associated angioedema

  Pare, G., Kubo, M., Byrd, J. B., McCarty, C. A., Woodard-Grice, A., Teo, K. K., Anand, S. S., Zuvich, R. L., Bradford, Y., Ross, S., Nakamura, Y., Ritchie, M. & Brown, N. J., 09-2013, In: Pharmacogenetics and genomics. 23, 9, p. 470-478 9 p.

  研究成果: Article › 査読

  • Angioedema
  • Angiotensin-Converting Enzyme Inhibitors
  • Telmisartan
  • Ramipril
  • MME
  49 被引用数 (Scopus)

• Genetic variants associated with uncontrolled blood pressure on thiazide diuretic/β-blocker combination therapy in the PEAR (Pharmacogenomic Evaluation Of Antihypertensive Responses) and INVEST (International Verapamil-SR Trandolapril Study) trials

  Magvanjav, O., Gong, Y., McDonough, C. W., Chapman, A. B., Turner, S. T., Gums, J. G., Bailey, K. R., Boerwinkle, E., Beitelshees, A. L., Tanaka, T., Kubo, M., Pepine, C. J., Cooper-DeHoff, R. M. & Johnson, J. A., 01-11-2017, In: Journal of the American Heart Association. 6, 11, e006522.

  研究成果: Article › 査読

  • trandolapril
  • Sodium Chloride Symporter Inhibitors
  • Pharmacogenetics
  • Verapamil
  • Antihypertensive Agents
  3 被引用数 (Scopus)

• Genetic variants associated with warfarin dose in African-American individuals: A genome-wide association study

  Perera, M. A., Cavallari, L. H., Limdi, N. A., Gamazon, E. R., Konkashbaev, A., Daneshjou, R., Pluzhnikov, A., Crawford, D. C., Wang, J., Liu, N., Tatonetti, N., Bourgeois, S., Takahashi, H., Bradford, Y., Burkley, B. M., Desnick, R. J., Halperin, J. L., Khalifa, S. I., Langaee, T. Y., Lubitz, S. A. & 22 others, Nutescu, E. A., Oetjens, M., Shahin, M. H., Patel, S. R., Sagreiya, H., Tector, M., Weck, K. E., Rieder, M. J., Scott, S. A., Wu, A. H. B., Burmester, J. K., Wadelius, M., Deloukas, P., Wagner, M. J., Mushiroda, T., Kubo, M., Roden, D. M., Cox, N. J., Altman, R. B., Klein, T. E., Nakamura, Y. & Johnson, J. A., 2013, In: The Lancet. 382, 9894, p. 790-796 7 p.

  研究成果: Article › 査読

  • Genome-Wide Association Study
  • Warfarin
  • African Americans
  • Cytochrome P-450 CYP2C9
  • Pharmacogenetics
  168 被引用数 (Scopus)

• Genetic variants in CPA6 and PRPF31 are associated with variation in response to metformin in individuals with type 2 diabetes

  Rotroff, D. M., Yee, S. W., Zhou, K., Marvel, S. W., Shah, H. S., Jack, J. R., Havener, T. M., Hedderson, M. M., Kubo, M., Herman, M. A., Gao, H., Mychaleckyi, J. C., McLeod, H. L., Doria, A., Giacomini, K. M., Pearson, E. R., Wagner, M. J., Buse, J. B. & Motsinger-Reif, A. A., 07-2018, In: Diabetes. 67, 7, p. 1428-1440 13 p.

  研究成果: Article › 査読

  • Metformin
  • Type 2 Diabetes Mellitus
  • Glucose
  • Feeding Behavior
  • Knockout Mice
  9 被引用数 (Scopus)

• Genetic variants in GPR126 are associated with adolescent idiopathic scoliosis

  Kou, I., Takahashi, Y., Johnson, T. A., Takahashi, A., Guo, L., Dai, J., Qiu, X., Sharma, S., Takimoto, A., Ogura, Y., Jiang, H., Yan, H., Kono, K., Kawakami, N., Uno, K., Ito, M., Minami, S., Yanagida, H., Taneichi, H., Hosono, N. & 21 others, Tsuji, T., Suzuki, T., Sudo, H., Kotani, T., Yonezawa, I., Londono, D., Gordon, D., Herring, J. A., Watanabe, K., Chiba, K., Kamatani, N., Jiang, Q., Hiraki, Y., Kubo, M., Toyama, Y., Tsunoda, T., Wise, C. A., Qiu, Y., Shukunami, C., Matsumoto, M. & Ikegawa, S., 06-2013, In: Nature Genetics. 45, 6, p. 676-679 4 p.

  研究成果: Article › 査読

  • Scoliosis
  • G-Protein-Coupled Receptors
  • Genome-Wide Association Study
  • Single Nucleotide Polymorphism
  • Chromosomes
  128 被引用数 (Scopus)

• Genetic variants in transcription factors are associated with the pharmacokinetics and pharmacodynamics of metformin

  Goswami, S., Yee, S. W., Stocker, S., Mosley, J. D., Kubo, M., Castro, R., Mefford, J. A., Wen, C., Liang, X., Witte, J., Brett, C., Maeda, S., Simpson, M. D., Hedderson, M. M., Davis, R. L., Roden, D. M., Giacomini, K. M. & Savic, R. M., 09-2014, In: Clinical Pharmacology and Therapeutics. 96, 3, p. 370-379 10 p.

  研究成果: Article › 査読

  • Metformin
  • Pharmacokinetics
  • Transcription Factors
  • Hepatocyte Nuclear Factor 4
  • Sp1 Transcription Factor
  46 被引用数 (Scopus)

• Genetic variants of calcium and vitamin D metabolism in kidney stone disease

  Howles, S. A., Wiberg, A., Goldsworthy, M., Bayliss, A. L., Gluck, A. K., Ng, M., Grout, E., Tanikawa, C., Kamatani, Y., Terao, C., Takahashi, A., Kubo, M., Matsuda, K., Thakker, R. V., Turney, B. W. & Furniss, D., 01-12-2019, In: Nature Communications. 10, 1, 5175.

  研究成果: Article › 査読

  Open Access

  • calciferol
  • kidney stones
  • Calcium-Sensing Receptors
  • Nephrolithiasis
  • Metabolism
  4 被引用数 (Scopus)

• Genetic variants of D2 but not D3 or D4 dopamine receptor gene are associated with rapid onset and poor prognosis of methamphetamine psychosis

  Ujike, H., Katsu, T., Okahisa, Y., Takaki, M., Kodama, M., Inada, T., Uchimura, N., Yamada, M., Iwata, N., Sora, I., Iyo, M., Ozaki, N. & Kuroda, S., 15-06-2009, In: Progress in Neuro-Psychopharmacology and Biological Psychiatry. 33, 4, p. 625-629 5 p.

  研究成果: Article › 査読

  • Dopamine D4 Receptors
  • Dopamine D3 Receptors
  • Methamphetamine
  • Psychotic Disorders
  • Genes
  29 被引用数 (Scopus)

• Genetic variants of RAMP2 and CLR are associated with stroke

  Koyama, T., Kuriyama, N., Ozaki, E., Matsui, D., Watanabe, I., Takeshita, W., Iwai, K., Watanabe, Y., Nakatochi, M., Shimanoe, C., Tanaka, K., Oze, I., Ito, H., Uemura, H., Katsuura-Kamano, S., Ibusuki, R., Shimoshikiryo, I., Takashima, N., Kadota, A., Kawai, S. & 14 others, Sasakabe, T., Okada, R., Hishida, A., Naito, M., Kuriki, K., Endoh, K., Furusyo, N., Ikezaki, H., Suzuki, S., Hosono, A., Mikami, H., Nakamura, Y., Kubo, M. & Wakai, K., 2017, In: Journal of atherosclerosis and thrombosis. 24, 12, p. 1267-1281 15 p.

  研究成果: Article › 査読

  • Calcitonin Receptor-Like Protein
  • Polymorphism
  • Single Nucleotide Polymorphism
  • Nucleotides
  • Stroke
  4 被引用数 (Scopus)

• Genetic variants of SLC17A1 are associated with cholesterol homeostasis and hyperhomocysteinaemia in Japanese men

  Koyama, T., Matsui, D., Kuriyama, N., Ozaki, E., Tanaka, K., Oze, I., Hamajima, N., Wakai, K., Okada, R., Arisawa, K., Mikami, H., Shimatani, K., Hirata, A., Takashima, N., Suzuki, S., Nagata, C., Kubo, M. & Tanaka, H., 03-11-2015, In: Scientific reports. 5, 15888.

  研究成果: Article › 査読

  • Hyperhomocysteinemia
  • Homeostasis
  • Cholesterol
  • Odds Ratio
  • Confidence Intervals
  3 被引用数 (Scopus)

• Genetic Variants on 3q21 and in the Sp8 Transcription Factor Gene (SP8) as Susceptibility Loci for Psychotic Disorders: A Genetic Association Study

  Kondo, K., Ikeda, M., Kajio, Y., Saito, T., Iwayama, Y., Aleksic, B., Yamada, K., Toyota, T., Hattori, E., Ujike, H., Inada, T., Kunugi, H., Kato, T., Yoshikawa, T., Ozaki, N. & Iwata, N., 13-08-2013, In: PloS one. 8, 8, e70964.

  研究成果: Article › 査読

  • Polymorphism
  • schizophrenia
  • Genetic Association Studies
  • Bipolar Disorder
  • single nucleotide polymorphism
  15 被引用数 (Scopus)

• Genetic variation affects de novo translocation frequency

  Kato, T., Inagaki, H., Yamada, K., Kogo, H., Ohye, T., Kowa, H., Nagaoka, K., Taniguchi, M., Emanuel, B. S. & Kurahashi, H., 17-02-2006, In: Science. 311, 5763, p. 971 1 p.

  研究成果: Article › 査読

  • Chromosomes, Human, Pair 11
  • Meiosis
  • Human Chromosomes
  • Genetic Variation
  • Alleles
  57 被引用数 (Scopus)

• Genetic variation determines VEGF-A plasma levels in cancer patients

  Innocenti, F., Jiang, C., Sibley, A. B., Etheridge, A. S., Hatch, A. J., Denning, S., Niedzwiecki, D., Shterev, I. D., Lin, J., Furukawa, Y., Kubo, M., Kindler, H. L., Auman, J. T., Venook, A. P., Hurwitz, H. I., McLeod, H. L., Ratain, M. J., Gordan, R., Nixon, A. B. & Owzar, K., 01-12-2018, In: Scientific reports. 8, 1, 16332.

  研究成果: Article › 査読

  • Genetic Variation
  • Vascular Endothelial Growth Factor A
  • Angiogenic Proteins
  • Colorectal Neoplasms
  • Neoplasms
  3 被引用数 (Scopus)

• Genetic Variation in the Indoleamine 2,3-Dioxygenase Gene in Pre-eclampsia

  Nishizawa, H., Kato, T., Ota, S., Nishiyama, S., Pryor-Koishi, K., Suzuki, M., Tsutsumi, M., Inagaki, H., Kurahashi, H. & Udagawa, Y., 01-07-2010, In: American Journal of Reproductive Immunology. 64, 1, p. 68-76 9 p.

  研究成果: Article › 査読

  • Indoleamine-Pyrrole 2,3,-Dioxygenase
  • Pre-Eclampsia
  • Genetic Variation
  • Homozygote
  • Genes
  8 被引用数 (Scopus)

• Genetic Variation in the Indoleamine 2,3-Dioxygenase Gene in Pre-eclampsia (Reply)

  Nishizawa, H. & Kurahashi, H., 01-11-2010, In: American Journal of Reproductive Immunology. 64, 5, p. 317 1 p.

  研究成果: Letter › 査読

• Genetic Variation in the SLC8A1 Calcium Signaling Pathway Is Associated with Susceptibility to Kawasaki Disease and Coronary Artery Abnormalities

  Shimizu, C., Eleftherohorinou, H., Wright, V. J., Kim, J., Alphonse, M. P., Perry, J. C., Cimaz, R., Burgner, D., Dahdah, N., Hoang, L. T., Khor, C. C., Salgado, A., Tremoulet, A. H., Davila, S., Kuijpers, T. W., Hibberd, M. L., Johnson, T. A., Takahashi, A., Tsunoda, T., Kubo, M. & 6 others, Tanaka, T., Onouchi, Y., Yeung, R. S. M., Coin, L. J. M., Levin, M. & Burns, J. C., 01-12-2016, In: Circulation: Cardiovascular Genetics. 9, 6, p. 559-568 10 p.

  研究成果: Article › 査読

  • Mucocutaneous Lymph Node Syndrome
  • Calcium Signaling
  • Genetic Variation
  • Genome-Wide Association Study
  • Coronary Vessels
  24 被引用数 (Scopus)

• Genetic variation of blood proteins within and between local populations of grivet monkey (Cercopithecus aethiops aethiops) in Central ethiopia

  Shimada, M. K. & Shotake, T., 10-1997, In: Primates. 38, 4, p. 399-414 16 p.

  研究成果: Article › 査読

  • Cercopithecus aethiops
  • Ethiopia
  • blood proteins
  • monkeys
  • genetic variation
  10 被引用数 (Scopus)