A case of a diabetic patient with alcoholic liver cirrhosis in which glucose intolerance has improved markedly after Hassab's operation for portal hypertension

Seiko Takefuji, Shouko Nakajima, Miyuki Shibata, Mariko Itoh, Masaaki Matsunaga, Noriko Kusada, Takao Kunoh, Yoshio Nomura

研究成果: Article査読

抄録

The patient was a 60-year-old Japanese man with chronic alcoholism who presented with lower limb edema, abdominal distension and hyperglycemia(plasma glucose, 501 mg/dl;HbA1c, 9.2 %). A diagnosis of diabetes mellitus with liver cirrhosis was made and insulin therapy (48-64 IU/day) was started in 2010. For half a year the patient was under good diabetic control, however, his condition deteriorated (FPG; 408 mg/dl and HbA1c; 11.5 %). He was admitted with portal hypertension and Hassabs' surgery was performed in 2011. Following surgery, he made a recovery from portal hypertension and an improvement was observed in his diabetic-control. His glucose intolerance improved and insulin therapy was discontinued. He was discharged under good diabetic control (HbA1c; 5.5 %) with glimepiride treatment (0.5 mg/day). The glimepiride treatment was eventually ceased. We hope this case report will help some readers treat patients with portal hypertension and insulin-resistant diabetes mellitus more effectively.

本文言語English
ページ(範囲)458-464
ページ数7
ジャーナルJournal of the Japan Diabetes Society
58
7
出版ステータスPublished - 2015
外部発表はい

All Science Journal Classification (ASJC) codes

  • 内科学
  • 内分泌学、糖尿病および代謝内科学
  • 内分泌学

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