A case of acquired hepatocerebral degeneration with prominent improvement of parkinsonism and cognitive deficits after living-donor liver transplantation

Tetsuro Ishihara, Mizuki Ito, Hirohisa Watanabe, Masatoshi Ishigami, Tetsuya Kiuchi, Gen Sobue

研究成果: ジャーナルへの寄稿学術論文査読

1 被引用数 (Scopus)

抄録

A 53-year-old woman visited us for a neurological consultation before her liver transplantation. She had a history of primary biliary cirrhosis that began at 37 years of age. She showed falling episodes and met with a traffic accident at 52 years old. Since then, her symptoms had worsened. The neurological examination showed masked face, rigidity on bilateral arms and legs, and lack of balance. Her Mini-Mental State Examination Score was 28/30, but she suffered from loss of memory and had trouble with executive function in detailed examinations. Her T1 weighted image showed hyperintensity in bilateral globus pallidus, putamen, dentate nucleus and cerebral peduncle. There was a significant improvement in intellectual function and neurological signs 6 months after her orthotopic liver transplantation. In addition, post-liver transplantation images showed a decrease in the area of hyperintensities. This case suggests that even in a patient with severe liver cirrhosis a complete cure of neurological manifestations can be obtained after the liver transplantation.

本文言語英語
ページ(範囲)581-584
ページ数4
ジャーナルClinical Neurology
52
8
DOI
出版ステータス出版済み - 08-2012
外部発表はい

All Science Journal Classification (ASJC) codes

  • 臨床神経学

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