A case of laryngotracheal amyloidosis treated with laryngotracheoplasty

Localized laryngotracheal amyloidosis is rare, and therapeutic strategy yet to be determined. We report a case of localized laryngotracheal amyloidosis as an intraluminal tracheal mass compromising respiration. A 53-year-old woman was seen for severe dyspnea. Flexible laryngoscopy indicated subglottic stenosis, with computed tomography and magnetic resonance imaging showing a large mass lesion in the tracheal membrane. After tracheotomy, laryngotracheofissure was done for biopsy and to reduce the mass at the trachea and subglottic region, preserving as much mucosa as possible. Postoperative pathology was amyloidosis. Due to the limited effect of surgical reduction, another laryngotracheal fissure was done to completely remove the tracheal mass. The raw postresection surface was covered by atelocollagen sheet, with posterior cricoid split added to enlarge the subglottic area. The Postoperative airway was sufficient and the tracheostoma closed. No recurrence has been found 6 months after final surgery. Complete resection using laryngotracheal fissure and simultaneous laryngotracheal reconstruction with atelocollagen sheet is thus effective in treating of laryngotrahceal amyloidosis and resolving airway stenosis.