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A Clinical Trial Evaluating the Usefulness of Tailored Antimicrobial Prophylaxis Using Rectal-culture Screening Media Prior to Transrectal Prostate Biopsy: A Multicenter, Randomized Controlled Trial

  • Takuya Sadahira
  • , Yuki Maruyama
  • , Yoshiki Hiyama
  • , Hiroyuki Kitano
  • , Hiroki Yamada
  • , Takayuki Goto
  • , Tsubasa Kondo
  • , Katsumi Shigemura
  • , Yosuke Mitsui
  • , Takehiro Iwata
  • , Kohei Edamura
  • , Motoo Araki
  • , Masami Watanabe
  • , Tadasu Takenaka
  • , Jun Teishima
  • , Yasuyoshi Miyata
  • , Kiyohito Ishikawa
  • , Ei Ichiro Takaoka
  • , Jun Miyazaki
  • , Satoshi Takahashi
  • Naoya Masumori, Hiroshi Kiyota, Masato Fujisawa, Shingo Yamamoto, Takafumi Sakuma, Norihiro Kusumi, Takaharu Ichikawa, Toyohiko Watanabe, Yoshitsugu Nasu, Masaya Tsugawa, Yasutomo Nasu, Koichiro Wada

研究成果: ジャーナルへの寄稿学術論文査読

2   !!Link opens in a new tab 被引用数 (Scopus)

抄録

The aim of this report is to introduce an on-going, multicenter, randomized controlled trial to evaluate whether tailored antimicrobial prophylaxis guided by rectal culture screening prevents acute bacterial prostatitis following transrectal prostate biopsy (TRPB). Patients will be randomized into an intervention or non-intervention group; tazobactam-piperacillin or levofloxacin will be prophylactically administered according to the results of rectal culture prior to TRPB in the intervention group whereas levofloxacin will be routinely given in the non-intervention group. The primary endpoint is the occurrence rate of acute bacterial prostatitis after TRPB. Recruitment begins in April, 2021 and the target total sample size is 5,100 participants.

本文言語英語
ページ(範囲)663-667
ページ数5
ジャーナルActa Medica Okayama
75
5
出版ステータス出版済み - 2021
外部発表はい

All Science Journal Classification (ASJC) codes

  • 生化学、遺伝学、分子生物学一般

フィンガープリント

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