A fluorogenic peptide probe developed by in vitro selection using tRNA carrying a fluorogenic amino acid

Wei Wang; Takanori Uzawa; Naoya Tochio; Jumpei Hamatsu; Yoshinori Hirano; Seiichi Tada; Hisao Saneyoshi; Takanori Kigawa; Nobuhiro Hayashi; Yutaka Ito; Makoto Taiji; Toshiro Aigaki; Yoshihiro Ito

doi:10.1039/c3cc47624c

A fluorogenic peptide probe developed by in vitro selection using tRNA carrying a fluorogenic amino acid

Wei Wang
, Takanori Uzawa
, Naoya Tochio
, Jumpei Hamatsu
, Yoshinori Hirano
, Seiichi Tada
, Hisao Saneyoshi
, Takanori Kigawa
, Nobuhiro Hayashi
, Yutaka Ito
, Makoto Taiji
, Toshiro Aigaki
, Yoshihiro Ito

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

28 被引用数 (Scopus)

抄録

A peptide that binds and emits fluorescence in response to conformational change in a target protein was developed by in vitro selection using tRNA carrying a fluorogenic amino acid. This technology could prove to be useful for the development of separation-free immunoassays and bio-imaging analyses.

本文言語	英語
ページ（範囲）	2962-2964
ページ数	3
ジャーナル	Chemical Communications
巻	50
号	22
DOI	https://doi.org/10.1039/c3cc47624c
出版ステータス	出版済み - 18-02-2014
外部発表	はい

All Science Journal Classification (ASJC) codes

電子材料、光学材料、および磁性材料
触媒
セラミックおよび複合材料
化学一般
表面、皮膜および薄膜
金属および合金
材料化学

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10.1039/c3cc47624c

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引用スタイル

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author = "Wei Wang and Takanori Uzawa and Naoya Tochio and Jumpei Hamatsu and Yoshinori Hirano and Seiichi Tada and Hisao Saneyoshi and Takanori Kigawa and Nobuhiro Hayashi and Yutaka Ito and Makoto Taiji and Toshiro Aigaki and Yoshihiro Ito",

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AU - Wang, Wei

AU - Uzawa, Takanori

AU - Tochio, Naoya

AU - Hamatsu, Jumpei

AU - Hirano, Yoshinori

AU - Tada, Seiichi

AU - Saneyoshi, Hisao

AU - Kigawa, Takanori

AU - Hayashi, Nobuhiro

AU - Ito, Yutaka

AU - Taiji, Makoto

AU - Aigaki, Toshiro

AU - Ito, Yoshihiro

PY - 2014/2/18

Y1 - 2014/2/18

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AB - A peptide that binds and emits fluorescence in response to conformational change in a target protein was developed by in vitro selection using tRNA carrying a fluorogenic amino acid. This technology could prove to be useful for the development of separation-free immunoassays and bio-imaging analyses.

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JO - Chemical Communications

JF - Chemical Communications

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ER -

A fluorogenic peptide probe developed by in vitro selection using tRNA carrying a fluorogenic amino acid

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