TY - JOUR
T1 - A Retrospective Analysis of the Relationship Between the Result of BRCA1/2 Genetic Testing and Surgical Method Selection in Japan
AU - Registration Committee of the Japanese HBOC consortium
AU - Inuzuka, Mayuko
AU - Watanabe, Chie
AU - Yokoyama, Shiro
AU - Kuwayama, Takashi
AU - Akashi-Tanaka, Sadako
AU - Arai, Masami
AU - Nakamura, Seigo
AU - Enomoto, Takayuki
AU - Nomizu, Tadashi
AU - Sakurai, Akihiro
AU - Sekine, Masayuki
AU - Nomura, Hiroyuki
AU - Ohkawa, Megumi
AU - Yotsumoto, Junko
N1 - Publisher Copyright:
© 2020 Elsevier Inc.
PY - 2021/2
Y1 - 2021/2
N2 - This study examined the relationship between BRCA1/2 genetic testing results and surgical method selection in patients with primary unilateral breast cancer in Japan. Compared with those without a mutation, patients with mutations tended to choose mastectomy. Additionally, all patients who underwent contralateral risk-reducing mastectomy were diagnosed with breast cancer before the age of 50 years.
AB - This study examined the relationship between BRCA1/2 genetic testing results and surgical method selection in patients with primary unilateral breast cancer in Japan. Compared with those without a mutation, patients with mutations tended to choose mastectomy. Additionally, all patients who underwent contralateral risk-reducing mastectomy were diagnosed with breast cancer before the age of 50 years.
KW - BRCA
KW - Breast cancer
KW - Prevention
KW - Risk-reducing surgery
KW - Surgical method selection
UR - http://www.scopus.com/inward/record.url?scp=85090746556&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85090746556&partnerID=8YFLogxK
U2 - 10.1016/j.clbc.2020.08.004
DO - 10.1016/j.clbc.2020.08.004
M3 - Article
C2 - 32928640
AN - SCOPUS:85090746556
SN - 1526-8209
VL - 21
SP - e48-e52
JO - Clinical Breast Cancer
JF - Clinical Breast Cancer
IS - 1
ER -
