A retrospective study of UFT and oral leucovorin plus PSK combination adjuvant chemotherapy in patients with stage III colon cancer

Kenji Tomizawa, Tsutomu Kumamoto, Yutaka Hanaoka, Shigeo Toda, Jin Moriyama, Shuichiro Matoba, Hiroya Kuroyanagi, Masaji Hashimoto, Harushi Udagawa, Goro Watanabe, Toshihito Sawada

研究成果: ジャーナルへの寄稿学術論文査読

抄録

Objective: To perform a retrospective analysis of UFT and oral leucovorin plus PSK combination adjuvant chemotherapy for stage III colon cancer in order to evaluate both treatment efficacy and toxicity. Subjects: Between 2003 and 2009, 273 stage III colon cancer patients underwent surgery in our institute, and we studied 156 of them. Results: Patients' median age was 72 years old; 87 men and 69 women. Of all patients, 119 had stage IIIa and 37 had stage IIIb. The 3-year disease, free survival rates for stage III, stage IIIa and stage IIIb patients were 73.9% and 80.6% and 51.4%, respectively, and the 3-year overall survival rates for stage III was 97.6%. With regard to toxicity, liver function disorder was observed in 9.6% of the patients as the most frequent adverse event, but there was no grade 3 or 4 toxicity. Conclusion: UFT and oral leucovorin plus PSK combination adjuvant chemotherapy for stage III colon cancer showed a good response especially for stage IIIa.

本文言語英語
ページ(範囲)571-575
ページ数5
ジャーナルJapanese Journal of Cancer and Chemotherapy
39
4
出版ステータス出版済み - 04-2012
外部発表はい

All Science Journal Classification (ASJC) codes

  • 腫瘍学
  • 癌研究

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