Abnormalities in the upper gastrointestinal tract in inflammatory bowel disease

T. Ando, K. Nobata, O. Watanabe, K. Kusugami, O. Maeda, K. Ishiguro, N. Ohmiya, Y. Niwa, H. Goto

研究成果: Review article査読

7 被引用数 (Scopus)

抄録

The predominant histopathologic feature of inflammatory bowel disease is the infiltration of acute and chronic inflammatory cells, including polymorphonuclear neutrophils, macrophages and lymphocytes, in the affected intestine. Helicobacter pylori is recognized as the most common cause of upper gastrointestinal lesions, and Helicobacter pylori-associated gastritis is characterized by increased numbers of acute and chronic inflammatory cells. The pathogenesis of inflammatory bowel disease or Helicobacter pylori-associated gastritis involves immunological abnormalities, including the deficient or excessive expression of cytokines. The chronic inflammatory process in patients with Crohn's disease may affect any part of the gastrointestinal tract, whereas ulcerative colitis affects mainly the colon and rectum. Here, we discuss abnormalities in the upper gastrointestinal tract in inflammatory bowel disease. Although the prevalence rate of Helicobacter pylori infection is low in Crohn's disease, these patients often have abnormalities in the upper gastrointestinal tract.

本文言語English
ページ(範囲)101-104
ページ数4
ジャーナルInflammopharmacology
15
3
DOI
出版ステータスPublished - 06-2007
外部発表はい

All Science Journal Classification (ASJC) codes

  • Immunology
  • Pharmacology
  • Pharmacology (medical)

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