Acceleration of Phagocytosis in Human Neutrophils Incubated with Gabexate Mesilate

K. Mikawa, H. Akamatsu, N. Maekawa, K. Nishina, H. Obara, Y. Niwa

研究成果: Article査読

7 被引用数 (Scopus)

抄録

It has recently been shown that gabexate mesilate inhibited human neutrophil functions including chemotaxis and reactive oxygen species production. In the present study, the effects of gabexate mesilate on phagocytosis by human neutrophils in vitro were investigated. Gabexate mesilate significantly enhanced neutrophil phagocytosis in a dose-dependent manner. This characteristic of gabexate mesilate may facilitate protection against infecting micro-organisms, although the inhibition of reactive oxygen species production by neutrophils may be a disadvantage for host-defense against infection.

本文言語English
ページ(範囲)292-295
ページ数4
ジャーナルJournal of International Medical Research
22
5
DOI
出版ステータスPublished - 09-1994
外部発表はい

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Cell Biology
  • Biochemistry, medical

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