Adherence of lyme disease spirochetes to rat lymphocytes

Donato Fumarola; M. Costanza Cedola; Ginevra Guanti; Akihiro Matsuura; Toshimistu Uede; Emilio Jirillo

doi:10.1016/S0176-6724(86)80117-1

Adherence of lyme disease spirochetes to rat lymphocytes

Donato Fumarola
, M. Costanza Cedola
, Ginevra Guanti
, Akihiro Matsuura
, Toshimistu Uede
, Emilio Jirillo

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

4 被引用数 (Scopus)

抄録

In the present work, the capacity of Lyme disease (LD) Spirochetes to spontaneously adhere to rat lymphocytes has been evaluated. Borrelia organisms adhere to thymus, spleen, Payer's patches and peripheral blood lymphocytes in a higher frequency than that observed with Salmonella minnesota R345 (Rb) used as reference strain. Employing enriched splenic T and B cell populations, Spirochete binding to B lymphocytes is more elevated than that obtained with Salmonella, while similar percentage of T cells forms rosettes with both microorganisms. Taken together, these findings provide evidence for a novel mode of interaction between LD Spirochetes and host immune system.

本文言語	英語
ページ（範囲）	146-150
ページ数	5
ジャーナル	Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology
巻	263
号	1-2
DOI	https://doi.org/10.1016/S0176-6724(86)80117-1
出版ステータス	出版済み - 1986
外部発表	はい

All Science Journal Classification (ASJC) codes

免疫学

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10.1016/S0176-6724(86)80117-1

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引用スタイル

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title = "Adherence of lyme disease spirochetes to rat lymphocytes",

abstract = "In the present work, the capacity of Lyme disease (LD) Spirochetes to spontaneously adhere to rat lymphocytes has been evaluated. Borrelia organisms adhere to thymus, spleen, Payer's patches and peripheral blood lymphocytes in a higher frequency than that observed with Salmonella minnesota R345 (Rb) used as reference strain. Employing enriched splenic T and B cell populations, Spirochete binding to B lymphocytes is more elevated than that obtained with Salmonella, while similar percentage of T cells forms rosettes with both microorganisms. Taken together, these findings provide evidence for a novel mode of interaction between LD Spirochetes and host immune system.",

author = "Donato Fumarola and Cedola, \{M. Costanza\} and Ginevra Guanti and Akihiro Matsuura and Toshimistu Uede and Emilio Jirillo",

year = "1986",

doi = "10.1016/S0176-6724(86)80117-1",

language = "English",

volume = "263",

pages = "146--150",

journal = "Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology",

issn = "0176-6724",

publisher = "Gustav Fischer Verlag",

number = "1-2",

}

Adherence of lyme disease spirochetes to rat lymphocytes. / Fumarola, Donato; Cedola, M. Costanza; Guanti, Ginevra その他.
In: Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology, Vol. 263, No. 1-2, 1986, p. 146-150.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

TY - JOUR

T1 - Adherence of lyme disease spirochetes to rat lymphocytes

AU - Fumarola, Donato

AU - Cedola, M. Costanza

AU - Guanti, Ginevra

AU - Matsuura, Akihiro

AU - Uede, Toshimistu

AU - Jirillo, Emilio

PY - 1986

Y1 - 1986

N2 - In the present work, the capacity of Lyme disease (LD) Spirochetes to spontaneously adhere to rat lymphocytes has been evaluated. Borrelia organisms adhere to thymus, spleen, Payer's patches and peripheral blood lymphocytes in a higher frequency than that observed with Salmonella minnesota R345 (Rb) used as reference strain. Employing enriched splenic T and B cell populations, Spirochete binding to B lymphocytes is more elevated than that obtained with Salmonella, while similar percentage of T cells forms rosettes with both microorganisms. Taken together, these findings provide evidence for a novel mode of interaction between LD Spirochetes and host immune system.

AB - In the present work, the capacity of Lyme disease (LD) Spirochetes to spontaneously adhere to rat lymphocytes has been evaluated. Borrelia organisms adhere to thymus, spleen, Payer's patches and peripheral blood lymphocytes in a higher frequency than that observed with Salmonella minnesota R345 (Rb) used as reference strain. Employing enriched splenic T and B cell populations, Spirochete binding to B lymphocytes is more elevated than that obtained with Salmonella, while similar percentage of T cells forms rosettes with both microorganisms. Taken together, these findings provide evidence for a novel mode of interaction between LD Spirochetes and host immune system.

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UR - https://www.scopus.com/pages/publications/0022892519#tab=citedBy

U2 - 10.1016/S0176-6724(86)80117-1

DO - 10.1016/S0176-6724(86)80117-1

M3 - Article

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AN - SCOPUS:0022892519

SN - 0176-6724

VL - 263

SP - 146

EP - 150

JO - Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology

JF - Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology

IS - 1-2

ER -

Adherence of lyme disease spirochetes to rat lymphocytes

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