Adult-onset Still's Disease complicated by autoimmune hepatitis: Successful treatment with infliximab

Kenji Fujii, Ryo Rokutanda, Yasuhiro Osugi, Yoshinobu Koyama, Toshiyuki Ota

研究成果: Article査読

20 被引用数 (Scopus)

抄録

A 17-year-old woman was previously diagnosed with autoimmune hepatitis (AIH) by liver biopsy. Adultonset Still's disease (AOSD) was subsequently diagnosed on the basis of high fever, arthralgia, erythema, leukocytosis (>80% granulocytes), cervical lymph node swelling, splenomegaly, and hyperferritinemia. Her symptoms and liver dysfunction improved with prednisolone of 60 mg daily and subsequently methotrexate was added. However her symptoms and liver dysfunction relapsed when prednisolone was tapered to 20 mg/ day. Therefore infliximab was introduced additionally and her symptoms and liver dysfunction subsided. To our knowledge, this is the first reported case of AOSD with AIH diagnosed by liver biopsy.

本文言語English
ページ(範囲)1125-1128
ページ数4
ジャーナルInternal Medicine
51
9
DOI
出版ステータスPublished - 2012
外部発表はい

All Science Journal Classification (ASJC) codes

  • Internal Medicine

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