Amino acid sequence of a putative transposase protein of the medaka fish transposable element Tol2 deduced from mRNA nucleotide sequences

Akihiko Koga, Miho Suzuki, Yuki Maruyama, Makiko Tsutsumi, Hiroshi Hori

研究成果: ジャーナルへの寄稿学術論文査読

26 被引用数 (Scopus)

抄録

Tol2 is a terminal-inverted repeat transposable element of the medaka fish Oryzias latipes. It is one of a few elements of this class so far demonstrated to be active in vertebrates, thus providing a unique tool for establishing a gene tagging system. For the purpose of identifying its transposase, we analyzed the structures of mRNAs originating from the Tol2 element. The results indicated that transcription of Tol2 is initiated at several sites, the four open reading frames in Tol2 roughly corresponding to exons, and that two main forms of mRNAs, covering exons 1-4 and exons 2-4, are present in medaka fish cells. One or both of these mRNAs are likely to encode a transposase, the amino acid sequence of which was deduced. Copyright (C) 1999 Federation of European Biochemical Societies.

本文言語英語
ページ(範囲)295-298
ページ数4
ジャーナルFEBS Letters
461
3
DOI
出版ステータス出版済み - 19-11-1999
外部発表はい

All Science Journal Classification (ASJC) codes

  • 生物理学
  • 構造生物学
  • 生化学
  • 分子生物学
  • 遺伝学
  • 細胞生物学

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