TY - JOUR
T1 - An autopsy case report of fulminant myocarditis
T2 - Following mRNA COVID-19 vaccination
AU - Hoshino, Naoki
AU - Yanase, Masanobu
AU - Ichiyasu, Taisuke
AU - Kuwahara, Kazuhiko
AU - Kawai, Hideki
AU - Muramatsu, Takashi
AU - Ishii, Hideki
AU - Tsukamoto, Tetsuya
AU - Morimoto, Shin ichiro
AU - Izawa, Hideo
N1 - Funding Information:
The authors would like to thank MARUZEN-YUSHODO Co. Ltd. (https://kw.maruzen.co.jp/kousei-honyaku/) for the English language editing.
Publisher Copyright:
© 2022 Elsevier Ltd
PY - 2022/12
Y1 - 2022/12
N2 - There have been few case reports on fatal outcomes in patients with acute myocarditis after mRNA coronavirus disease 2019 (COVID-19) vaccination. In most cases of myocarditis after mRNA COVID-19 vaccination, the myocarditis is mild, and the prognosis is good. Here we report an autopsy case of fulminant myocarditis following mRNA COVID-19 vaccination. Learning objective: The global distribution of the mRNA coronavirus disease 2019 vaccine requires consideration of appropriate treatment for postvaccination myocarditis. Eosinophil-mediated immunological injury to cardiomyocytes can be involved in the cause of fulminant inflammation from the pathological findings of postvaccination myocarditis.
AB - There have been few case reports on fatal outcomes in patients with acute myocarditis after mRNA coronavirus disease 2019 (COVID-19) vaccination. In most cases of myocarditis after mRNA COVID-19 vaccination, the myocarditis is mild, and the prognosis is good. Here we report an autopsy case of fulminant myocarditis following mRNA COVID-19 vaccination. Learning objective: The global distribution of the mRNA coronavirus disease 2019 vaccine requires consideration of appropriate treatment for postvaccination myocarditis. Eosinophil-mediated immunological injury to cardiomyocytes can be involved in the cause of fulminant inflammation from the pathological findings of postvaccination myocarditis.
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U2 - 10.1016/j.jccase.2022.06.006
DO - 10.1016/j.jccase.2022.06.006
M3 - Article
AN - SCOPUS:85134796480
VL - 26
SP - 391
EP - 394
JO - Journal of Cardiology Cases
JF - Journal of Cardiology Cases
SN - 1878-5409
IS - 6
ER -