Analysis of facial skin-resident microbiota in Japanese acne patients

Shigeki Numata, Hirohiko Akamatsu, Narifumi Akaza, Akiko Yagami, Satoru Nakata, Kayoko Matsunaga

研究成果: Article査読

16 被引用数 (Scopus)


Objectives: We investigated the facial skin microbiota of Japanese acne patients. Methods: Skin swab samples were obtained from 100 acne patients and 28 healthy controls to evaluate Propionibacterium and Staphylococcus spp. using a culture method. Malassezia spp. were evaluated using a nonculture method. Antibiotic resistance of Propionibacterium spp. was also examined. Results: Acne patients and controls did not show significant differences in Propionibacterium and Staphylococcus spp. populations. However, the number of Malassezia globosa from patients was greater than that from controls. Moreover, the number of Propionibacterium spp. from patients carrying antibiotic-resistant strains was significantly greater than that from patients not carrying them. Conclusions: The present study characterized the facial skin microbiota of Japanese acne patients, suggesting a correlation between acne and quantitative differences in Malassezia microbiota. It was also found that the antibiotic resistance of Propionibacterium spp. may affect its abundance in the skin.

出版ステータスPublished - 01-02-2014

All Science Journal Classification (ASJC) codes

  • Dermatology

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