Analysis of facial skin-resident microbiota in Japanese acne patients

Shigeki Numata, Hirohiko Akamatsu, Narifumi Akaza, Akiko Yagami, Satoru Nakata, Kayoko Matsunaga

研究成果: Article

11 引用 (Scopus)

抄録

Objectives: We investigated the facial skin microbiota of Japanese acne patients. Methods: Skin swab samples were obtained from 100 acne patients and 28 healthy controls to evaluate Propionibacterium and Staphylococcus spp. using a culture method. Malassezia spp. were evaluated using a nonculture method. Antibiotic resistance of Propionibacterium spp. was also examined. Results: Acne patients and controls did not show significant differences in Propionibacterium and Staphylococcus spp. populations. However, the number of Malassezia globosa from patients was greater than that from controls. Moreover, the number of Propionibacterium spp. from patients carrying antibiotic-resistant strains was significantly greater than that from patients not carrying them. Conclusions: The present study characterized the facial skin microbiota of Japanese acne patients, suggesting a correlation between acne and quantitative differences in Malassezia microbiota. It was also found that the antibiotic resistance of Propionibacterium spp. may affect its abundance in the skin.

元の言語English
ページ(範囲)86-92
ページ数7
ジャーナルDermatology
228
発行部数1
DOI
出版物ステータスPublished - 01-02-2014

Fingerprint

Microbiota
Acne Vulgaris
Propionibacterium
Skin
Malassezia
Microbial Drug Resistance
Staphylococcus
Anti-Bacterial Agents
Population

All Science Journal Classification (ASJC) codes

  • Dermatology

これを引用

Numata, S., Akamatsu, H., Akaza, N., Yagami, A., Nakata, S., & Matsunaga, K. (2014). Analysis of facial skin-resident microbiota in Japanese acne patients. Dermatology, 228(1), 86-92. https://doi.org/10.1159/000356777
Numata, Shigeki ; Akamatsu, Hirohiko ; Akaza, Narifumi ; Yagami, Akiko ; Nakata, Satoru ; Matsunaga, Kayoko. / Analysis of facial skin-resident microbiota in Japanese acne patients. :: Dermatology. 2014 ; 巻 228, 番号 1. pp. 86-92.
@article{bc400cdf9c8d437490688866b59012ab,
title = "Analysis of facial skin-resident microbiota in Japanese acne patients",
abstract = "Objectives: We investigated the facial skin microbiota of Japanese acne patients. Methods: Skin swab samples were obtained from 100 acne patients and 28 healthy controls to evaluate Propionibacterium and Staphylococcus spp. using a culture method. Malassezia spp. were evaluated using a nonculture method. Antibiotic resistance of Propionibacterium spp. was also examined. Results: Acne patients and controls did not show significant differences in Propionibacterium and Staphylococcus spp. populations. However, the number of Malassezia globosa from patients was greater than that from controls. Moreover, the number of Propionibacterium spp. from patients carrying antibiotic-resistant strains was significantly greater than that from patients not carrying them. Conclusions: The present study characterized the facial skin microbiota of Japanese acne patients, suggesting a correlation between acne and quantitative differences in Malassezia microbiota. It was also found that the antibiotic resistance of Propionibacterium spp. may affect its abundance in the skin.",
author = "Shigeki Numata and Hirohiko Akamatsu and Narifumi Akaza and Akiko Yagami and Satoru Nakata and Kayoko Matsunaga",
year = "2014",
month = "2",
day = "1",
doi = "10.1159/000356777",
language = "English",
volume = "228",
pages = "86--92",
journal = "Dermatology",
issn = "1018-8665",
publisher = "S. Karger AG",
number = "1",

}

Numata, S, Akamatsu, H, Akaza, N, Yagami, A, Nakata, S & Matsunaga, K 2014, 'Analysis of facial skin-resident microbiota in Japanese acne patients', Dermatology, 巻. 228, 番号 1, pp. 86-92. https://doi.org/10.1159/000356777

Analysis of facial skin-resident microbiota in Japanese acne patients. / Numata, Shigeki; Akamatsu, Hirohiko; Akaza, Narifumi; Yagami, Akiko; Nakata, Satoru; Matsunaga, Kayoko.

:: Dermatology, 巻 228, 番号 1, 01.02.2014, p. 86-92.

研究成果: Article

TY - JOUR

T1 - Analysis of facial skin-resident microbiota in Japanese acne patients

AU - Numata, Shigeki

AU - Akamatsu, Hirohiko

AU - Akaza, Narifumi

AU - Yagami, Akiko

AU - Nakata, Satoru

AU - Matsunaga, Kayoko

PY - 2014/2/1

Y1 - 2014/2/1

N2 - Objectives: We investigated the facial skin microbiota of Japanese acne patients. Methods: Skin swab samples were obtained from 100 acne patients and 28 healthy controls to evaluate Propionibacterium and Staphylococcus spp. using a culture method. Malassezia spp. were evaluated using a nonculture method. Antibiotic resistance of Propionibacterium spp. was also examined. Results: Acne patients and controls did not show significant differences in Propionibacterium and Staphylococcus spp. populations. However, the number of Malassezia globosa from patients was greater than that from controls. Moreover, the number of Propionibacterium spp. from patients carrying antibiotic-resistant strains was significantly greater than that from patients not carrying them. Conclusions: The present study characterized the facial skin microbiota of Japanese acne patients, suggesting a correlation between acne and quantitative differences in Malassezia microbiota. It was also found that the antibiotic resistance of Propionibacterium spp. may affect its abundance in the skin.

AB - Objectives: We investigated the facial skin microbiota of Japanese acne patients. Methods: Skin swab samples were obtained from 100 acne patients and 28 healthy controls to evaluate Propionibacterium and Staphylococcus spp. using a culture method. Malassezia spp. were evaluated using a nonculture method. Antibiotic resistance of Propionibacterium spp. was also examined. Results: Acne patients and controls did not show significant differences in Propionibacterium and Staphylococcus spp. populations. However, the number of Malassezia globosa from patients was greater than that from controls. Moreover, the number of Propionibacterium spp. from patients carrying antibiotic-resistant strains was significantly greater than that from patients not carrying them. Conclusions: The present study characterized the facial skin microbiota of Japanese acne patients, suggesting a correlation between acne and quantitative differences in Malassezia microbiota. It was also found that the antibiotic resistance of Propionibacterium spp. may affect its abundance in the skin.

UR - http://www.scopus.com/inward/record.url?scp=84896721431&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84896721431&partnerID=8YFLogxK

U2 - 10.1159/000356777

DO - 10.1159/000356777

M3 - Article

C2 - 24356463

AN - SCOPUS:84896721431

VL - 228

SP - 86

EP - 92

JO - Dermatology

JF - Dermatology

SN - 1018-8665

IS - 1

ER -