Apocrine papillary lesion: comparison of pathological findings from 22 years previously and the present

Yuki Nomoto, Heiji Yoshinaka, Yasuyo Ohi, Naoki Hayashi, Ayako Nagata, Kazunobu Sueyoshi, Yuka Eguchi, Yoshiaki Shinden, Yuko Kijima, Shoji Natsugoe

研究成果: Article査読

1 被引用数 (Scopus)

抄録

Apocrine papillary lesion (APL) is difficult to diagnose as benign or malignant. We experienced an APL remaining in the body for 22 years. We present a case of a 71-year-old woman who had undergone excisional biopsy 22 years previously at the first hospital that she visited. 1 year previously, she had undergone fine-needle aspiration cytology at a second hospital, and the lesion was diagnosed as potentially malignant. She underwent core-needle biopsy at a third hospital, but whether the lesion was benign or malignant could not be definitively diagnosed. We performed right mastectomy and sentinel lymph-node biopsy, because her tumor was suspected to be malignant based on imaging means, and malignancy could not be ruled out on either biopsy or cytology. The histopathological diagnosis was tiny foci of apocrine proliferative lesion with massive hemorrhagic necrosis and no tumor metastasis in two sentinel lymph nodes. Retrospectively, we compared all of the patient’s previous specimens with the present ones, and applied the recent pathological diagnostic criteria. Although the biopsy specimen excised 22 years ago suggested an encapsulated apocrine papillary carcinoma or a papilloma with apocrine ductal carcinoma in situ, neither infiltration nor metastasis has occurred. Furthermore, neither the pathological findings nor the clinical behavior has changed over time.

本文言語English
ページ(範囲)524-528
ページ数5
ジャーナルBreast Cancer
26
4
DOI
出版ステータスPublished - 01-07-2019
外部発表はい

All Science Journal Classification (ASJC) codes

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Pharmacology (medical)

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