抄録
Introduction: DNA methylation in the CpG sites of intron 1 of HIF3A is associated with body mass index (BMI). This cross-sectional study investigated correlations between DNA methylation of HIF3A and BMI or adiposity parameters in the Japanese population. Method: DNA methylation of HIF3A was quantified via pyrosequencing. Result: DNA methylation of HIF3A differed only in women; DNA methylation level at cg27146050 was associated with visceral adipose tissue thickness and correlated with BMI and percent (%) body fat after excluding smokers. Conclusion: Peripheral blood DNA methylation at the CpG site (cg27146050) of HIF3A correlated with VAT thickness in Japanese women.
本文言語 | 英語 |
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ページ(範囲) | 130-137 |
ページ数 | 8 |
ジャーナル | Endocrine Research |
巻 | 47 |
号 | 3-4 |
DOI | |
出版ステータス | 出版済み - 2022 |
All Science Journal Classification (ASJC) codes
- 内分泌学