@article{07ee9d4ec03341328f9354437b383972,
title = "Association between the Extent of Peripheral Blood DNA Methylation of HIF3A and Accumulation of Adiposity in community-dwelling Women: The Yakumo Study",
abstract = "Introduction: DNA methylation in the CpG sites of intron 1 of HIF3A is associated with body mass index (BMI). This cross-sectional study investigated correlations between DNA methylation of HIF3A and BMI or adiposity parameters in the Japanese population. Method: DNA methylation of HIF3A was quantified via pyrosequencing. Result: DNA methylation of HIF3A differed only in women; DNA methylation level at cg27146050 was associated with visceral adipose tissue thickness and correlated with BMI and percent (%) body fat after excluding smokers. Conclusion: Peripheral blood DNA methylation at the CpG site (cg27146050) of HIF3A correlated with VAT thickness in Japanese women.",
author = "Genki Mizuno and Hiroya Yamada and Eiji Munetsuna and Mirai Yamazaki and Yoshitaka Ando and Ryosuke Fujii and Yoshiki Tsuboi and Atsushi Teshigawara and Itsuki Kageyama and Keisuke Osakabe and Keiko Sugimoto and Hiroaki Ishikawa and Naohiro Ichino and Yoshiji Ohta and Koji Ohashi and Shuji Hashimoto and Koji Suzuki",
note = "Funding Information: This work was supported by the Japan Society for the Promotion of Science (JSPS) under Grants-in-Aid for Scientific Research under Grant numbers 26293144, 17K09139, 16H06277 and 20K10515. We thank the participants and staff of the Health Examination Program for Residents of Yakumo, Hokkaido, Japan. We also appreciate bioRxiv for accepting this article as a preprint; the preprint doi is 10.1101/2020.11.30.403709. Publisher Copyright: {\textcopyright} 2022 Taylor & Francis Group, LLC.",
year = "2022",
doi = "10.1080/07435800.2022.2121967",
language = "English",
volume = "47",
pages = "130--137",
journal = "Endocrine Research",
issn = "0743-5800",
publisher = "Informa Healthcare",
number = "3-4",
}