Association of serum phytoestrogen concentration and dietary habits in a sample set of the JACC Study

Kotaro Ozasa, Masahiro Nakao, Yoshiyuki Watanabe, Kyohei Hayashi, Tsuneharu Miki, Kazuya Mikami, Mitsuru Mori, Fumio Sakauchi, Masakazu Washio, Yoshinori Ito, Koji Suzuki, Tatsuhiko Kubo, Kenji Wakai, Akiko Tamakoshi, Yutaka Motohashi, Ichiro Tsuji, Yosikazu Nakamura, Hiroyasu Iso, Haruo Mikami, Yutaka Inaba & 21 others Yoshiharu Hoshiyama, Hiroshi Suzuki, Hiroyuki Shimizu, Hideaki Toyoshima, Shinkan Tokudome, Shuji Hashimoto, Shogo Kikuchi, Akio Koizumi, Takashi Kawamura, Chigusa Date, Kiyomi Sakata, Takayuki Nose, Norihiko Hayakawa, Takesumi Yoshimura, Akira Shibata, Naoyuki Okamoro, Hideo Shio, Yoshiyuki Ohno, Tomoyuki Kitagawa, Toshio Kuroki, Kazuo Tajima

研究成果: Article

32 引用 (Scopus)

抄録

Background: Phytoestrogens may be associated with a reduced risk of hormone dependent neoplasms such as prostate and breast cancers. We tried to determine the validity of the association between serum phytoestrogen concentrations and dietary habits obtained from a food frequency questionnaire used in the Japan Collaborative Cohort Study (JACC Study) for Evaluation of Cancer Risk sponsored by the Ministry of Education, Science, Sports and Culture of Japan (Monbusho). Methods: The subjects were 151 male controls who were selected for a nested case-control study for evaluating prostate cancer risk as part of the JACC Study. Dietary habits were determined using a food frequency questionnaire at baseline, and the concentrations of genistein, daidzein, and equol in frozen-stored serum samples assayed in 2002 were compared. Results: Tofu intake showed a significant association with the serum concentrations of genistein and daidzein (Spearman's correlation coefficients (rs) =0.30 and 0.27, respectively), and miso soup showed a slight association with serum concentrations of these phytoestrogens. In contrast, serum concentrations of equol were not associated with dietary intake of tofu and miso soup. After adjustment for serum daidzein concentration, serum equol concentration was associated with the intake of foods containing fat, meat, and coffee, but not green tea. Conclusions: Serum genistein and daidzein concentrations were significantly associated with dietary intake of tofu, and slightly with intake of miso soup. Consumption of fat, meat, and coffee may be associated with equol production by intestinal microflora in this sample set.

元の言語English
ジャーナルJournal of epidemiology
15
発行部数SUPPL. 2
DOI
出版物ステータスPublished - 14-10-2005

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Phytoestrogens
Feeding Behavior
Soy Foods
Japan
Cohort Studies
Equol
Serum
Genistein
Coffee
Hormone-Dependent Neoplasms
Meat
Prostatic Neoplasms
Fats
Food
Tea
Sports
Case-Control Studies
Eating
Breast Neoplasms
Education

All Science Journal Classification (ASJC) codes

  • Epidemiology

これを引用

Ozasa, K., Nakao, M., Watanabe, Y., Hayashi, K., Miki, T., Mikami, K., ... Tajima, K. (2005). Association of serum phytoestrogen concentration and dietary habits in a sample set of the JACC Study. Journal of epidemiology, 15(SUPPL. 2). https://doi.org/10.2188/jea.15.S196
Ozasa, Kotaro ; Nakao, Masahiro ; Watanabe, Yoshiyuki ; Hayashi, Kyohei ; Miki, Tsuneharu ; Mikami, Kazuya ; Mori, Mitsuru ; Sakauchi, Fumio ; Washio, Masakazu ; Ito, Yoshinori ; Suzuki, Koji ; Kubo, Tatsuhiko ; Wakai, Kenji ; Tamakoshi, Akiko ; Motohashi, Yutaka ; Tsuji, Ichiro ; Nakamura, Yosikazu ; Iso, Hiroyasu ; Mikami, Haruo ; Inaba, Yutaka ; Hoshiyama, Yoshiharu ; Suzuki, Hiroshi ; Shimizu, Hiroyuki ; Toyoshima, Hideaki ; Tokudome, Shinkan ; Hashimoto, Shuji ; Kikuchi, Shogo ; Koizumi, Akio ; Kawamura, Takashi ; Date, Chigusa ; Sakata, Kiyomi ; Nose, Takayuki ; Hayakawa, Norihiko ; Yoshimura, Takesumi ; Shibata, Akira ; Okamoro, Naoyuki ; Shio, Hideo ; Ohno, Yoshiyuki ; Kitagawa, Tomoyuki ; Kuroki, Toshio ; Tajima, Kazuo. / Association of serum phytoestrogen concentration and dietary habits in a sample set of the JACC Study. :: Journal of epidemiology. 2005 ; 巻 15, 番号 SUPPL. 2.
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title = "Association of serum phytoestrogen concentration and dietary habits in a sample set of the JACC Study",
abstract = "Background: Phytoestrogens may be associated with a reduced risk of hormone dependent neoplasms such as prostate and breast cancers. We tried to determine the validity of the association between serum phytoestrogen concentrations and dietary habits obtained from a food frequency questionnaire used in the Japan Collaborative Cohort Study (JACC Study) for Evaluation of Cancer Risk sponsored by the Ministry of Education, Science, Sports and Culture of Japan (Monbusho). Methods: The subjects were 151 male controls who were selected for a nested case-control study for evaluating prostate cancer risk as part of the JACC Study. Dietary habits were determined using a food frequency questionnaire at baseline, and the concentrations of genistein, daidzein, and equol in frozen-stored serum samples assayed in 2002 were compared. Results: Tofu intake showed a significant association with the serum concentrations of genistein and daidzein (Spearman's correlation coefficients (rs) =0.30 and 0.27, respectively), and miso soup showed a slight association with serum concentrations of these phytoestrogens. In contrast, serum concentrations of equol were not associated with dietary intake of tofu and miso soup. After adjustment for serum daidzein concentration, serum equol concentration was associated with the intake of foods containing fat, meat, and coffee, but not green tea. Conclusions: Serum genistein and daidzein concentrations were significantly associated with dietary intake of tofu, and slightly with intake of miso soup. Consumption of fat, meat, and coffee may be associated with equol production by intestinal microflora in this sample set.",
author = "Kotaro Ozasa and Masahiro Nakao and Yoshiyuki Watanabe and Kyohei Hayashi and Tsuneharu Miki and Kazuya Mikami and Mitsuru Mori and Fumio Sakauchi and Masakazu Washio and Yoshinori Ito and Koji Suzuki and Tatsuhiko Kubo and Kenji Wakai and Akiko Tamakoshi and Yutaka Motohashi and Ichiro Tsuji and Yosikazu Nakamura and Hiroyasu Iso and Haruo Mikami and Yutaka Inaba and Yoshiharu Hoshiyama and Hiroshi Suzuki and Hiroyuki Shimizu and Hideaki Toyoshima and Shinkan Tokudome and Shuji Hashimoto and Shogo Kikuchi and Akio Koizumi and Takashi Kawamura and Chigusa Date and Kiyomi Sakata and Takayuki Nose and Norihiko Hayakawa and Takesumi Yoshimura and Akira Shibata and Naoyuki Okamoro and Hideo Shio and Yoshiyuki Ohno and Tomoyuki Kitagawa and Toshio Kuroki and Kazuo Tajima",
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Ozasa, K, Nakao, M, Watanabe, Y, Hayashi, K, Miki, T, Mikami, K, Mori, M, Sakauchi, F, Washio, M, Ito, Y, Suzuki, K, Kubo, T, Wakai, K, Tamakoshi, A, Motohashi, Y, Tsuji, I, Nakamura, Y, Iso, H, Mikami, H, Inaba, Y, Hoshiyama, Y, Suzuki, H, Shimizu, H, Toyoshima, H, Tokudome, S, Hashimoto, S, Kikuchi, S, Koizumi, A, Kawamura, T, Date, C, Sakata, K, Nose, T, Hayakawa, N, Yoshimura, T, Shibata, A, Okamoro, N, Shio, H, Ohno, Y, Kitagawa, T, Kuroki, T & Tajima, K 2005, 'Association of serum phytoestrogen concentration and dietary habits in a sample set of the JACC Study', Journal of epidemiology, 巻. 15, 番号 SUPPL. 2. https://doi.org/10.2188/jea.15.S196

Association of serum phytoestrogen concentration and dietary habits in a sample set of the JACC Study. / Ozasa, Kotaro; Nakao, Masahiro; Watanabe, Yoshiyuki; Hayashi, Kyohei; Miki, Tsuneharu; Mikami, Kazuya; Mori, Mitsuru; Sakauchi, Fumio; Washio, Masakazu; Ito, Yoshinori; Suzuki, Koji; Kubo, Tatsuhiko; Wakai, Kenji; Tamakoshi, Akiko; Motohashi, Yutaka; Tsuji, Ichiro; Nakamura, Yosikazu; Iso, Hiroyasu; Mikami, Haruo; Inaba, Yutaka; Hoshiyama, Yoshiharu; Suzuki, Hiroshi; Shimizu, Hiroyuki; Toyoshima, Hideaki; Tokudome, Shinkan; Hashimoto, Shuji; Kikuchi, Shogo; Koizumi, Akio; Kawamura, Takashi; Date, Chigusa; Sakata, Kiyomi; Nose, Takayuki; Hayakawa, Norihiko; Yoshimura, Takesumi; Shibata, Akira; Okamoro, Naoyuki; Shio, Hideo; Ohno, Yoshiyuki; Kitagawa, Tomoyuki; Kuroki, Toshio; Tajima, Kazuo.

:: Journal of epidemiology, 巻 15, 番号 SUPPL. 2, 14.10.2005.

研究成果: Article

TY - JOUR

T1 - Association of serum phytoestrogen concentration and dietary habits in a sample set of the JACC Study

AU - Ozasa, Kotaro

AU - Nakao, Masahiro

AU - Watanabe, Yoshiyuki

AU - Hayashi, Kyohei

AU - Miki, Tsuneharu

AU - Mikami, Kazuya

AU - Mori, Mitsuru

AU - Sakauchi, Fumio

AU - Washio, Masakazu

AU - Ito, Yoshinori

AU - Suzuki, Koji

AU - Kubo, Tatsuhiko

AU - Wakai, Kenji

AU - Tamakoshi, Akiko

AU - Motohashi, Yutaka

AU - Tsuji, Ichiro

AU - Nakamura, Yosikazu

AU - Iso, Hiroyasu

AU - Mikami, Haruo

AU - Inaba, Yutaka

AU - Hoshiyama, Yoshiharu

AU - Suzuki, Hiroshi

AU - Shimizu, Hiroyuki

AU - Toyoshima, Hideaki

AU - Tokudome, Shinkan

AU - Hashimoto, Shuji

AU - Kikuchi, Shogo

AU - Koizumi, Akio

AU - Kawamura, Takashi

AU - Date, Chigusa

AU - Sakata, Kiyomi

AU - Nose, Takayuki

AU - Hayakawa, Norihiko

AU - Yoshimura, Takesumi

AU - Shibata, Akira

AU - Okamoro, Naoyuki

AU - Shio, Hideo

AU - Ohno, Yoshiyuki

AU - Kitagawa, Tomoyuki

AU - Kuroki, Toshio

AU - Tajima, Kazuo

PY - 2005/10/14

Y1 - 2005/10/14

N2 - Background: Phytoestrogens may be associated with a reduced risk of hormone dependent neoplasms such as prostate and breast cancers. We tried to determine the validity of the association between serum phytoestrogen concentrations and dietary habits obtained from a food frequency questionnaire used in the Japan Collaborative Cohort Study (JACC Study) for Evaluation of Cancer Risk sponsored by the Ministry of Education, Science, Sports and Culture of Japan (Monbusho). Methods: The subjects were 151 male controls who were selected for a nested case-control study for evaluating prostate cancer risk as part of the JACC Study. Dietary habits were determined using a food frequency questionnaire at baseline, and the concentrations of genistein, daidzein, and equol in frozen-stored serum samples assayed in 2002 were compared. Results: Tofu intake showed a significant association with the serum concentrations of genistein and daidzein (Spearman's correlation coefficients (rs) =0.30 and 0.27, respectively), and miso soup showed a slight association with serum concentrations of these phytoestrogens. In contrast, serum concentrations of equol were not associated with dietary intake of tofu and miso soup. After adjustment for serum daidzein concentration, serum equol concentration was associated with the intake of foods containing fat, meat, and coffee, but not green tea. Conclusions: Serum genistein and daidzein concentrations were significantly associated with dietary intake of tofu, and slightly with intake of miso soup. Consumption of fat, meat, and coffee may be associated with equol production by intestinal microflora in this sample set.

AB - Background: Phytoestrogens may be associated with a reduced risk of hormone dependent neoplasms such as prostate and breast cancers. We tried to determine the validity of the association between serum phytoestrogen concentrations and dietary habits obtained from a food frequency questionnaire used in the Japan Collaborative Cohort Study (JACC Study) for Evaluation of Cancer Risk sponsored by the Ministry of Education, Science, Sports and Culture of Japan (Monbusho). Methods: The subjects were 151 male controls who were selected for a nested case-control study for evaluating prostate cancer risk as part of the JACC Study. Dietary habits were determined using a food frequency questionnaire at baseline, and the concentrations of genistein, daidzein, and equol in frozen-stored serum samples assayed in 2002 were compared. Results: Tofu intake showed a significant association with the serum concentrations of genistein and daidzein (Spearman's correlation coefficients (rs) =0.30 and 0.27, respectively), and miso soup showed a slight association with serum concentrations of these phytoestrogens. In contrast, serum concentrations of equol were not associated with dietary intake of tofu and miso soup. After adjustment for serum daidzein concentration, serum equol concentration was associated with the intake of foods containing fat, meat, and coffee, but not green tea. Conclusions: Serum genistein and daidzein concentrations were significantly associated with dietary intake of tofu, and slightly with intake of miso soup. Consumption of fat, meat, and coffee may be associated with equol production by intestinal microflora in this sample set.

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U2 - 10.2188/jea.15.S196

DO - 10.2188/jea.15.S196

M3 - Article

VL - 15

JO - Journal of Epidemiology

JF - Journal of Epidemiology

SN - 0917-5040

IS - SUPPL. 2

ER -