Bar-shaped nuclear chromatin in conjunctival samples: With cytologic features and ultrastructural correlation

Tadao K. Kobayashi, Youichi Ishida, Chiyuki Kaneko, Kazuo Tsubota

研究成果: Article査読

4 被引用数 (Scopus)

抄録

OBJECTIVE: To study the cytomorphologic features of bar-shaped chromatin in conjunctival samples and assess whether there are morphologic similarities between nuclear grooves seen in thyroid papillary carcinoma and bar-shaped chromatin. STUDY DESIGN: A total of 10 conjunctival samples from five volunteers were studied cytologically. Of the 10 samples, 2 showed bar- shaped chromatin. This chromatin was studied using a light microscope, scanning electron microscope (SEM) and transmission electron microscope (TEM). RESULTS: On SEM, bar-shaped chromatin was observed as a fissure or shallow cracks. On TEM the bar-shaped chromatin existed both in the center of the nuclei and in the nuclear membrane and cytoplasm. It was surrounded by outer and inner membranes. CONCLUSION: It seems that bar-shaped chromatin is formed by the nuclear membrane and that these changes are essentially the same configuration as cytoplasmic invaginations commonly present in papillary carcinoma of the thyroid.

本文言語English
ページ(範囲)1129-1132
ページ数4
ジャーナルActa Cytologica
42
5
DOI
出版ステータスPublished - 01-01-1998

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Histology

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