TY - JOUR
T1 - Biochemical and physical analysis of subcellular membranes in rat parotid gland enlarged by chronic isoproterenol administration
AU - Mizuno, Masako
AU - Yashiro, Koji
AU - Kameyama, Yasunaga
AU - Hayashi, Shigeo
AU - Sakashita, Yuzuru
AU - Yokota, Yutaka
N1 - Funding Information:
Acknowledgements--We are thankful to Ms Teruyo Tanahashi for her helpful assistance. This study was supported in part by a grant from Miyata Science Research Foundation of Asahi University and Grant-in-Aid for Scientific research from the Ministry of Education, Science and Culture, Japan.
PY - 1990
Y1 - 1990
N2 - 1. 1. Chronic administration of isoproterenol caused similar alterations of membrane lipid profile in at least two rat parotid subcellular fractions, secretory granular and microsomal. 2. 2. Typical changes in phospholipid classes and fatty-acyl chain groups were an increase of phosphatidylcholine and a decrease of sphingomyelin, and an increase of octadecadienoyl chain and a decreaes of eicosatetraenoyl chain, respectively. 3. 3. Electron spin resonance study showed that the isoproterenol-treatment also affected a membrane physical property, which may be through these compositional changes in membrane constituents.
AB - 1. 1. Chronic administration of isoproterenol caused similar alterations of membrane lipid profile in at least two rat parotid subcellular fractions, secretory granular and microsomal. 2. 2. Typical changes in phospholipid classes and fatty-acyl chain groups were an increase of phosphatidylcholine and a decrease of sphingomyelin, and an increase of octadecadienoyl chain and a decreaes of eicosatetraenoyl chain, respectively. 3. 3. Electron spin resonance study showed that the isoproterenol-treatment also affected a membrane physical property, which may be through these compositional changes in membrane constituents.
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U2 - 10.1016/0305-0491(90)90358-Z
DO - 10.1016/0305-0491(90)90358-Z
M3 - Article
C2 - 2364669
AN - SCOPUS:0025265281
SN - 0305-0491
VL - 96
SP - 171
EP - 176
JO - Comparative Biochemistry and Physiology -- Part B: Biochemistry and
JF - Comparative Biochemistry and Physiology -- Part B: Biochemistry and
IS - 1
ER -