Biochemical markers of bone turnover. New aspect. Biochemical markers of bone turnover in long term treatment with bisphosphonate

Shogo Asano, Atsushi Suzuki, Mitsuyasu Itoh

研究成果: Review article査読

抄録

Bisphosphonates (BPs) are now widely used for the prevention of osteoporotic fracture. The elevation of bone turnover markers (BTM) is an independent risk factor for the bone fracture, and their significant decrease with BPs treatment is considered to reflect BPs' efficacy to "adjust" bone turnover. A large-scale study so far showed that BPs continuously suppress both BTM levels and the incidence of fracture as long as 7 to 10 years, though possible deterioration of bone strength with long-term severe suppression of BTM has been pointed out.

本文言語English
ページ(範囲)1179-1185
ページ数7
ジャーナルClinical calcium
19
8
出版ステータスPublished - 08-2009

All Science Journal Classification (ASJC) codes

  • 医学(全般)

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